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12241
Extracellular acyl-CoA-binding protein as an independent biomarker of COVID-19 disease severity
Published 2025-01-01Get full text
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12242
Integrated multi-omics profiling reveals the role of the DNA methylation landscape in shaping biological heterogeneity and clinical behaviour of metastatic melanoma
Published 2025-07-01“…Abstract Background We developed an integrated multi-omics analysis in metastatic melanoma (MM) cohorts to associate DNA methylation profiles with tumor progression, survival, response to adjuvant immunotherapy, structure of the tumor immune microenvironment and transcriptional programs of immunity and melanoma differentiation. …”
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12243
The application of blockchain with a comparative approach and its impact on risk, flexibility and internal control evaluation
Published 2024-09-01“…Blockchain is essentially a public ledger, where groups of transactions or events are recorded and stored in a chain-like data structure; this approach creates a fast yet secure way to transfer funds. …”
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12244
Mannich Base Derived from Lawsone Inhibits PKM2 and Induces Neoplastic Cell Death
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12245
MSA-3D: Dissecting Galaxies at z ∼ 1 with High Spatial and Spectral Resolution
Published 2025-01-01“…Here we describe the multiplexed slit-stepping method, which is >15 times more efficient than the NIRSpec IFS mode for our program. As an example of the data quality, we present a case study of an individual galaxy at z = 1.104 (stellar mass M _* = 10 ^10.3 M _⊙ , star formation rate, SFR = 3 M _⊙ yr ^−1 ) with prominent face-on spiral structure. …”
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12246
A multi-omics reciprocal analysis for characterization of bacterial metabolism
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12248
How do individuals with mental health disorder and spinal cord injury gain access to participate in voluntary sport groups in Switzerland?
Published 2025-01-01“…The coaches’ point of view was included to have a complementary perspective compared to the athletes to produce comprehensive insights. A semi-structured interview guideline was developed, discussed with experts and tested in a pilot interview (Braun & Clarke, 2022; Smith & Sparkes, 2020). …”
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12249
A computational DNA methylation method to remove contaminated DNA from spent embryo culture medium for noninvasive preimplantation genetic testingResearch in context
Published 2025-04-01“…At the heart of ART success is preimplantation genetic testing (PGT), which enables the detection of chromosomal anomalies, single-gene disorders, and structural rearrangements, enhancing embryo selection and mitigating genetic risk. …”
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12250
exoALMA. XVII. Characterizing the Gas Dynamics around Dust Asymmetries
Published 2025-01-01“…While dust observations have revealed crescent structures in several disks, observations of their kinematic signatures are still lacking. …”
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12251
Dynamics of turnover of sugar-lowering drugs in the retail segment of the pharmaceutical market from 2020 to 2024
Published 2025-07-01“…Despite maintaining the leading position of metformin, the consumption structure is shifting towards more expensive schemes. …”
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12252
Psychometric evaluation of EQ-5D-5L in OHCA survivors from the TTM2 trial: a post hoc analysis
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12254
The Sant Pau Initiative on Neurodegeneration (SPIN) cohort: A data set for biomarker discovery and validation in neurodegenerative disorders
Published 2019-01-01“…Methods Participants of the SPIN cohort provide informed consent to donate blood and cerebrospinal fluid samples, receive detailed neurological and neuropsychological evaluations, and undergo a structural 3T brain MRI scan. A subset also undergoes other functional or imaging studies (video‐polysomnogram, 18F‐fluorodeoxyglucose PET, amyloid PET, Tau PET). …”
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概念為本跨領域課程發展之研究—以國際文憑組織中學階段課程為例 Concept-Based Interdisciplinary Curriculum Development in International Baccalaureate Schools in Taiwan– The International Baccalaureate Middle Years...
Published 2024-12-01“…These adjustments also promoted continual professional development and created reform momentum for teachers. (4) The development of concept-based interdisciplinary approaches varied across academic subjects because of differences in the systemic structures of their curriculum frameworks. For example, relative to the other subjects, Mathematics and Sciences underwent fewer adjustments in knowledge content. …”
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12257
Propuesta metodológica para la enseñanza de la biomedicina orientada a las herramientas de detección y diagnóstico molecular para estudiantes de Medicina
Published 2025-03-01“…Methods: The proposed structure is based on the requirements of basic science subjects that students must complete to understand molecular diagnostics. …”
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Relationship between prenatal anxiety, depression, pregnancy stress and their social determinants
Published 2025-08-01“…Given that psychological problems during pregnancy may lead to short-term and long-term adverse outcomes for both mothers and infants, clarifying their network structure and core social determinants holds important public health significance for formulating regional intervention strategies. …”
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12260
Evaluating snow depth retrievals from Sentinel-1 volume scattering over NASA SnowEx sites
Published 2024-11-01Get full text
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