Amphotericin B tissue penetration and pharmacokinetics in healthy and Candida albicans-infected rats: insights from microdialysis and population modeling by Valdeene Vieira Santos, Valdeene Vieira Santos, Laiz Campos Pereira, Laiz Campos Pereira, Jackeline Marley Santos de Araújo, Jackeline Marley Santos de Araújo, Matheus Antônio da Hora Borges, Matheus Antônio da Hora Borges, Carolina Magalhães Brandão, Luisa Oliveira Santos, Luisa Oliveira Santos, Cristiane Flora Villarreal, Francine Johansson Azeredo

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Development of entrustable professional activities framework for clinical microbiology residency: a national multi-step consensus using modified Delphi study by Mennatallah H. Rizk, Niveen Ghoraba, Hanaa S. Elhoshy, Omayma Hamed

“…As the first step, a thorough literature review was undertaken to identify potential EPAs pertinent to clinical microbiology residency programs. Then, evaluation of EPAs for quality and structure using EQual rubric involved five experts in medical education and clinical microbiology, resulting in the confirmation of relevant EPAs. …”
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Rapid Genotyping of <i>FecB</i> Mutation in Sheep Using CRISPR-Cas12a Integrated with DNA Nanotree Biosensing Platform by Dongxia Pan, Mukaddas Mijit, Hui Wang, Chaoqun Sun, Bantan Pingcuo, Zhixue Yu, Benhai Xiong, Xiangfang Tang

“…A similar DNA origami technique-based fluorescence reporter nanotree structure was synthesized using gold nanomagnetic beads as carriers to amplify the fluorescence signal further. …”
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Early findings from the integration of hypertension care into differentiated service delivery models for HIV in Uganda: a mixed‐method study by John Baptist Kiggundu, Fred C. Semitala, Chelsea Faith Lipoto, Lilian Giibwa, Robert Twine, Savio Mwaka, Florence Ayebare, Christine Kiwala, Evelyn N. Magambo, Gerald Mutungi, Isaac Ssinabulya, Donna Spiegelman, James Kayima, Martin Muddu, Jeremy I. Schwartz, Anne R. Katahoire, Chris T. Longenecker

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Neuroimaging and kinematic biomarkers of post-stroke upper limb motor impairment by Joyce L. Chen, Timothy K. Lam, Melanie C. Baniña, Daniele Piscitelli, Mindy F. Levin

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Geohazard Features of the Ionian Calabrian Margin by S. Ceramicola, A. Cova, E. Forlin, N. Markezic, G. Mangano, D. Civile, M. Zecchin, F. Fanucci, E. Colizza, C. Corselli, D. Morelli, A. Savini, A. Caburlotto, O. Candoni, M. Coste, D. Cotterle, S. Critelli, A. Cuppari, M. Deponte, R. Dominici, L. Facchin, E. Gordini, M. Locatelli, F. Muto, D. Praeg, R. Romeo, C. Tessarolo

“…These include multiple coastal landslides, failure scars along open slopes, shelf-indenting retrogressive canyon headwalls and active fluid venting structures, that we investigated by integrating regional high-resolution multibeam sonar and sub-bottom profiling data. …”
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Deuterium retention in tungsten oxide: the role of oxide damage by Mykola Ialovega, Celine Martin, Cédric Pardanaud, Elodie Bernard, Martiane Cabié, Andrea Campos, Christian Grisolia, Marco Minissale, Thomas Neisius, Thierry Angot, Régis Bisson

“…The findings provide insight into the behavior of tungsten oxides under deuterium implantation, emphasizing the importance of considering its thermal stability and its structural modifications at the surface of tungsten plasma facing components.…”
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The issue of credibility between customers’ perceptions and the attitude toward Facebook advertising by Jassim Al-Gasawneh, Abdullah AlSokkar, Mahmoud Alghizzawi, Tahreer Abu Hmeidan, Deemah Alarabiat, Ahmed Alamro

“…This sample was chosen due to students’ high engagement with social media and their relevance as future marketing professionals, yielding 277 valid responses to be analyzed, and the hypotheses were tested using smart PLS through Structural Equation Modelling. The analysis revealed that Perceived Interactivity, Advertising Avoidance, and Privacy positively impacted attitudes towards Facebook advertisements, with coefficients and significance levels as follows: β = 0.122, t = 5.545, p &lt; 0.003, β = 0.324, t = 2.643, p &lt; 0.002, and β = 0.046, t = 3.833, p &lt; 0.003, respectively. …”
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High-quality bonds: serine acetyltransferase 2 gene revealed by GWAS is associated with grain protein content in spring durum wheat by Aleksey Ermolaev, Ludmila Bespalova, Varvara Korobkova, Aleksey Yanovsky, Lubov Nazarova, Aleksandra Kroupina, Anastasia Chernook, Aleksandra Mudrova, Viktoria Voronezhskaya, Viktoria Voronezhskaya, Pavel Kroupin, Gennady Karlov, Mikhail Divashuk, Mikhail Divashuk

“…A missense mutation (Gly325Ser) in the ninth exon of sat2 was associated with a 1.33% GPC increase in spring durum wheat recombinant inbred lines. Structural analysis indicated that the Gly325Ser mutation alters the SAT2 protein’s C-terminal α-helix, potentially influencing enzyme activity. …”
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The HPV101 E7 protein shares host cellular targets and biological activities with high-risk HPV16 E7 by Maya K. Gelbard, Miranda Grace, Annika von Schoeler-Ames, Ida Gnanou, Karl Munger

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Organic and Synthetic Substitutes in Tracheal Reconstruction: A Scoping Review (2015–2025) by Ana Caroline dos Santos, Guilherme Machado Holzlsauer, João Paulo Ruiz Lucio de Lima Parra, Raí André Querino Candelária, Thamires Santos da Silva, Rodrigo da Silva Nunes Barreto, Maria Angelica Miglino

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Highly selective HPK1 inhibitor NDI-101150 mediates immune cell activation and robust antitumor responses, distinct from immune checkpoint blockade by Samantha Carreiro, Christine Loh, Neelu Kaila, Fu-Shan Kuo, Scott Boiko, David N Ciccone, Joshua J McElwee, Peter J Tummino

“…Genetic HPK1 kinase inactivation or knockout in mice leads to immune cell activation and tumor growth suppression, providing a strong rationale for targeting HPK1 kinase activity as an immuno-oncology therapy.Methods A structure-guided drug design approach was used to identify a highly potent and selective small molecule inhibitor of HPK1 kinase activity, NDI-101150. …”
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Epidemiological Aspects of Monitoring the Sensitivity of <i>Staphylococcus aureus</i> Strains by N. Kh. Otamuratova, G. K. Abdukhalilova, D. R. Akhmedova, Yu. A. Tursunova

“…Conclusion. In the general structure of microorganisms of the hospital, Staphylococcus aureus strains prevailed (50%). …”
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Epigenetic Modifiers to Treat Retinal Degenerative Diseases by Evgenya Y. Popova, Lisa Schneper, Aswathy Sebastian, Istvan Albert, Joyce Tombran-Tink, Colin J. Barnstable

“…To extend our findings, we tested the hypothesis that this effect was due to altered chromatin structure by using a range of inhibitors of chromatin condensation to prevent photoreceptor degeneration in the rd10 mouse model. …”
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Dysphagia in pediatric intensive care unit patients (review) by I. A. Lisitsa, Yu. S. Aleksandrovich, A. N. Zavyalova, O. V. Lisovskii, S. A. Razumov

“…The review analyzes the causes, features of diagnosis and treatment of dysphagia in pediatric patients with PIСS. 5 groups of causes in the structure of PIСS that can lead to the development of dysphagia were considered: infectious-trophic, vegetative-metabolic, neuromuscular, emotional-cognitivecomplications and decreased quality of life compared to the premorbid level. …”
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First rangewide density estimate of the endemic and isolated Luangwa giraffe in Zambia by Catherine Sun, Frederike Otten, Rigardt Hoffman, Courtney Marneweck, Howard Maimbo, Charles-Albert Petre, Dusty Joubert, Tom Riffel, Matthew S. Becker, Stephanie Fennessy, Julian Fennessy, Michael B. Brown

“…However, sparse monitoring since the early 1900s has limited inferences about population size, structure, and range. To address this, we conducted the most spatially extensive and systematic survey to date of Luangwa giraffe across its distribution, extending survey effort 120 km south of their officially recognized extent. …”
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Identification and Analysis of the Plasma Membrane H⁺-ATPase Gene Family in Cotton and Its Roles in Response to Salt Stress by Cong Cheng, Fengyuan Zhang, Li Li, Zhiyong Ni

“…Chromosomal localization and collinearity analyses elucidated the distribution characteristics of this gene family within the cotton genomes. Gene structure and phylogenetic analyses demonstrated the conservation of this family across cotton species, whereas the examination of <i>cis</i>-acting elements in gene promoters highlighted their involvement in environmental stress and hormone response categories. …”
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Informational and analytical support of planning processes of marketing actions in high-speed trains by E. A. Makarova, K. V. Surzhin, S. S. Morozov, S. V. Muktepavel, I. N. Spesivtseva

“…The functionality created on the basis of ACS “Express” is a flexible system of reports that are formed at the user's request, allowing you to view information on the structure of passenger traffic with varying degrees of detail for compiling programs to stimulate demand and analyze its effectiveness.…”
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Clinical and epidemiological characteristic of chronic hepatitis C in the republic of Tyva by A. A. Saryglar, S. O. Dongak, A. D. Ibrohimova, K. E. Novak, E. V. Esaulenko

“…The clinical profile of typical patients with chronic hepatitis C was established; whose share in the total structure of the examined was 38.4%.  Conclusion: There is a tendency to reduce the incidence of chronic hepatitis C in the Republic of Tyva. …”
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Grassland bird nest ecology and survival in upland habitat buffers near wooded edges by Ross R. Conover, L. Wes Burger Jr., Eric T. Linder

“…Nest survival was influenced by among‐ and within‐season temporal effects and local vegetation structure, but not by buffer width. Nest success varied substantially between years and within seasons for dickcissel (12.9% and 19.1% early in the seasons of 2003 and 2004, respectively), but not for red‐winged blackbird (15.1%). …”
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