A New Model of Bone Remodelling by Justyna MIODOWSKA, Jan BIELSKI, Magdalena KROMKA-SZYDEK

“…The created model is used to predict the stress-stimulated change in callus density. …”
Get full text

Autocrine interferon poisoning mediates ADAR1-dependent synthetic lethality in BRCA1/2-mutant cancers by Roman M. Chabanon, Liudmila Shcherbakova, Magali Lacroix-Triki, Marine Aglave, Jean Zeghondy, Victor Kriaa, Antoine Gougé, Marlène Garrido, Elodie Edmond, Ludovic Bigot, Dragomir B. Krastev, Rachel Brough, Stephen J. Pettitt, Thibault Thomas-Bonafos, Robert Samstein, Christophe Massard, Marc Deloger, Andrew NJ Tutt, Fabrice Barlesi, Yohann Loriot, Suzette Delaloge, Marcel Tawk, Cindy Degerny, Yea-Lih Lin, Barbara Pistilli, Philippe Pasero, Christopher J. Lord, Sophie Postel-Vinay

“…Abstract ADAR1 is an RNA editing enzyme which prevents autoimmunity by blocking interferon responses triggered by cytosolic RNA sensors, and is a potential target in immuno-oncology. However, predictive biomarkers for ADAR1 inhibition are lacking. …”
Get full text

Effect of bio-psychosocial nursing intervention on emotional status, body image, and quality of life of women with polycystic ovarian syndrome: a quasi-experimental study by Hanaa M. Abo Shereda, Eman A. Shokr, Hanaa A. Radwan, Doaa Lotfi Afifi Alqersh, Shereen Roushdy Hashem, Ashraf Mohamed El-Saiyed Konsouh, Zeinab A. Kasemy, Hanan E. Nada

“…It frequently results in emotional stress, a low quality of life, and body image issues. …”
Get full text

Impaired DNAJB2 Response to Heat Shock in Fibroblasts from a Neuropathy Patient with <i>DNAJB2/HSJ1</i> Mutation: Cystamine as a Potential Therapeutic Intervention by Raj Kumar Pradhan, Nikolas G. Kinney, Brigid K. Jensen, Hristelina Ilieva

“…While homozygous mutations in DNAJB2/HSJ1 have been linked to early-onset neuropathy, a heterozygous DNAJB2 c.823+6C>T was discovered in an adult patient with severe sensory–motor polyneuropathy. This mutation is predicted to affect both isoforms of the protein. DNAJB2 (HSP40), a key member of the heat shock protein family, plays a critical role in cellular protection and stress, including response to heat shock. …”
Get full text

Carry-over effects in Culex species along a land use gradient with differences in microclimatic conditions by Carmen Villacañas de Castro, Johann Musculus, Esther Timmermann, Renke Lühken, Ellen Kiel, Felix Gregor Sauer

“…Results A piecewise structural equation model (SEM) was employed to simultaneously estimate the linear regression coefficients for various predicted relationships. The findings from the bivariate results align with the theoretical model derived from the SEM analysis. …”
Get full text

Perioperative factors influencing post-appendectomy outcomes in adults: a single-center prospective study in the North of Palestine by Alaa Zayed, Khaled Demyati, Abdulsalam Alkaiyat, Alaa Omari, Eliana Masri, Zain Saqfalhait, Yazan.N.A.Abdallah, Obayda Darawsha, Mohammed Hajhamad

“…Furthermore, the significant role of anxiety and depression in post-operative outcomes suggests that stress-reduction strategies and mental health support should be integrated into patient care. …”
Get full text

Hemodynamic assessment of rupture risk during growth stages in middle cerebral artery aneurysms treated with coiling by Rifaqat Ali, Hana Ihsan Hassan, Aman Sharma, Aashim Dhawan, P. Sharma, Waam Mohammed Taher, Mariem Alwan, Ali Fawzi Al-Hussainy, Mahmood Jasem Jawad, Hiba Mushtaq

“…In contrast, coiling consistently suppressed these metrics across all volumes: peak WSS fell below 100 Pa, average WSS remained under 5 Pa, and OSI was reduced to below 0.03. AWSS and OSI reductions indicated dampened flow oscillations and reduced biomechanical stress. …”
Get full text

Combining whole genome and transcriptome sequencing to analyze the pathogenic mechanism of Diplodia sapinea blight in Pinus sylvestris var. mongolica Litv. by Ruiqi Wang, Yuting Wang, Sina Fu, Shixian Liao, Tingbo Jiang, Boru Zhou

“…Differently expressed genes (DEGs) -based protein-protein interaction (PPI) network was constructed that included 163 pairs of significantly positively correlated proteins, forming three highly interacting gene clusters, and the PPI network was predicted to be associated with the replication and propagation processes of the fungus. …”
Get full text

Loudness Assessment of Musical Tones Equalized in A-weighted Level by Despina KLONARI, Konstantinos PASTIADIS, Georgios PAPADELIS, George PAPANIKOLAOU

“…Consequently, the use of elaborate computational prediction is stressed, in view of the necessity for thorough investigation of factors affecting the perception of loudness of musical sounds.…”
Get full text

Antibacterial Evaluation of Tricyclic Antidepressants Against <i>S. aureus</i> and the Possible Pathways of the Mechanism of Action by Vitória Pessoa de Farias Cabral, Daniel Sampaio Rodrigues, Lívia Gurgel do Amaral Valente Sá, Lara Elloyse Almeida Moreira, Cecília Rocha da Silva, João Batista de Andrade Neto, Érica Rayanne Mota da Costa, Thais Lima Ferreira, Leilson Carvalho de Oliveira, Beatriz Oliveira de Souza, Dávylla Rênnia Saldanha Pinheiro, Bruno Coêlho Cavalcanti, Islay Lima Magalhães, Manoel Odorico de Moraes, Hélio Vitoriano Nobre Júnior

“…The mechanism of TCAs, isolated and combined with OXA, was associated with a reduction in cell viability, resulting from their action on the bacterial genetic material and generation of oxidative stress. …”
Get full text

Lifestyle modifications and non-pharmacological management in elderly hypertension by Hao-Yuan Tsai, Hung-Jui Chuang, Wei-Hsiang Liao, Yi-Jie Wang, Pei-Hsuan Li, Wen-Ting Wang, Shih-Cheng Liao, Chih-Fan Yeh, Pey-Rong Chen, Tai-Shuan Lai, Hung-Ju Lin, Shao-Yi Cheng, Wen-Jone Chen, Yen-Hung Lin, Yi-Yao Chang

“…Many studies have examined the effectiveness of lifestyle modifications such as exercise, diet, weight loss, and stress reduction in controlling hypertension in elderly individuals, and several meta-analyses have reported that both aerobic and resistance exercise can reduce blood pressure in this population. …”
Get full text

Anti-inflammatory therapy for tendinopathy using Il1rn mRNA encapsulated in SM102 lipid nanoparticles by Yuan Zhang, Yuan Zhang, Xu Li, Hao Li, Ruiyang Zhang, Ti Zhang, Talante Juma, Yongfei Zhou, Quanyi Guo, Hui Zhao, Yongping Cao

Get full text

Investigation of state anxiety levels of parents admitted to the paediatric emergency department by Ahmet Yeşil, Ahmet Butun

“…Abstract Introduction The psychological well-being of parents during their child’s emergency treatment can significantly influence the overall care experience and outcomes. Parental stress and anxiety may affect their ability to provide accurate information, make informed decisions, and support their child effectively during treatment. …”
Get full text

Effect of subsolvus and supersolvus solution treatments on the high temperature creep behavior of TC21 titanium alloy with basket-weave microstructure by L.M. Chen, L.R. Xiao, Y.F. Xu, L.R. Zeng, X.J. Zhao, S. Zhang, C. Liu, Z. Fu

Get full text

A nationwide comparative analysis of the prevalance and determinants of non-communicable diseases risk factors between Jordanian and displaced Syrian populations by Nour Abdo, Sharifeh Almasaid, Ahlam J. Alhemedi, Ahmad Abdalmajeed Alghzawi, Albaraa Abu Ata, Izzaldin Albojuq

“…Lower education was also associated with higher odds of HTN, DM, and dyslipidemia in Jordanian population only. …”
Get full text

Historical water environment changes in Chagan Lake (mid-19th to mid-20th century) inferred from sedimentary diatom records by Fengyang Sui, Fengyang Sui, Xinxin Du, Henglin Xiao, Henglin Xiao, Shuying Zang, Hongkuan Hui, Qi Lv, Yan Liu, Nannan Zhang, Yawen Fan

Get full text

Lycium barbarum Glycopeptide Alleviates Neomycin‐Induced Ototoxicity by Inhibiting Tryptophan Hydroxylase‐Mediated Serotonin Biosynthesis by Yunhao Wu, Li Zhang, Shengda Cao, Jingwen Zhang, Cheng Li, Yunlong Shan, Qiuping Liu, Zhexiong Yu, Qiaojun Fang, Yuhua Zhang, Xiaolong Fu, Kwok‐Fai So, Renjie Chai

Get full text

Comparative study of LPBF Ta–Ti alloy: microstructural evolution and deformation behavior by Zhenyu Yang, Yuanhong Qiu, Jiangqi Zhu, Zhifeng Huang, Shengbin Dai, Weihu Yang, Min Liu, Gang Wang, Xingchen Yan, Wenhua Huang

Get full text

Caregiving burdens of task time and task difficulty among paid and unpaid caregivers of persons living with dementia by Matthew Lee Smith, Matthew Lee Smith, Jodi L. Southerland, Malinee Neelamegam, Gang Han, Gang Han, Shinduk Lee, Shinduk Lee, Chung Lin Kew, Juanita-Dawne R. Bacsu, Elyse Couch, Steffi M. Kim, Monique J. Brown, Ayse Malatyali, Lucas Wilson, Zahra Rahemi, Jeremy Holloway, Marcia G. Ory, Marcia G. Ory

Get full text

Modelos de materiales hiperelásticos para el análisis de los elastómeros usando el MEF // Hyperelastic material models for the analysis of elastomers by using FEM. by R. A. González Carbonell, E. Álvarez García, J. L. Moya Rodríguez, K. Abreu González

“…</p><p>____________________________________________________________________________</p><p>Abstract<br />This researching deals with the material models used by Finite Elements software to predict the<br />behavior of the stress and strain of hyperelastic materials. …”
Get full text