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5741
“I became alright after birth”: Mechanisms driving improvements in mental health symptoms in the postpartum transition among persons at risk for HIV in South Africa
Published 2025-08-01“…Background: Pregnant and postpartum persons (PPPs) are at increased risk for HIV acquisition, and depression and posttraumatic stress disorder (PTSD) negatively impact engagement in HIV prevention behaviors like pre-exposure prophylaxis (PrEP) use, thereby increasing risk. …”
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5742
PO32 | Effect of the sodium-glucose co-transporter-2 (SGLT2) inhibitors on platelet activation and lipid peroxidation: results of a pilot study
Published 2025-08-01“…Results: In patients treated with gliflozins, we observed significant reductions markers of platelet activation and oxidative stress: 11-dehydro-TXB2 (p=0.032) (Figure 1, panel A), 8-iso-prostaglandin (PG)F2α (p=0.026) (Figure 1, panel B). …”
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5743
Nature-based virtual reality relaxation to improve mental health and sleep in undergraduate students: A randomized controlled trial
Published 2025-08-01“…The VR intervention group showed significant reductions in perceived stress levels ( p = .001) and improvements in subjective sleep patterns ( p = .046), with these effects sustained at follow-up. …”
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5744
Mitogen‐activated protein kinase activity drives cell trajectories in colorectal cancer
Published 2021-08-01“…Experimental targeting of EGFR‐BRAF‐MEK in cancer organoids affected signaling and gene expression contingent on predictive KRAS/BRAF mutations and induced cell plasticity overriding default developmental trajectories. …”
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5745
Single nuclei RNA-sequencing unveils alveolar macrophages as drivers of endothelial damage in obese HFpEF-related pulmonary hypertension
Published 2025-07-01“…In vitro experiments were performed to study the mechanisms underlying metabolic stress-induced macrophage dysfunction using palmitic acid (PA), co-culture experiments were used to investigate the crosstalk between macrophages and endothelial cells. …”
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5746
Calidad de sueño, salud mental y actividad física en estudiantes universitarios de la Amazonía peruana (Sleep quality, mental health and physical activity in university students fr...
Published 2024-12-01“…In the context of higher education, sleep quality, mental health, and physical activity are key variables for understanding the overall well-being of students. …”
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5747
Détermination de l'influence du trajet de déformation sur la courbe limite de formage
Published 1996-09-01“… The aim of this study is to predict the strain path influence on the forming limit diagram, from the limit stress curve. …”
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5748
Nutritional status, psychological status and quality of life of adolescents in selected childcare institutions in the Galle district of Sri Lanka
Published 2025-04-01“…Psychological status and QoL were assessed via validated Sinhala versions of the Depression Anxiety and Stress Scale (DASS 21) and Peds QLTM Generic 4.0 core scale, respectively. …”
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5749
Hygro-mechanical model for concrete pavement with long-term drying analysis
Published 2023-07-01“…The validation covers autogenous and drying strain on the slab. The models predict drying-induced tensile stress up to 3.3 MPa, inducing additional loading on the slab, uncaptured by current design methods. …”
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5750
Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures
Published 2017-02-01“…Using a pan‐cancer analysis of CNA data from patient tumors and experimental systems, here we show that principal component analysis‐defined CNA signatures are predictive of glycolytic phenotypes, including 18F‐fluorodeoxy‐glucose (FDG) avidity of patient tumors, and increased proliferation. …”
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5751
Cuproptosis: a novel therapeutic mechanism in lung cancer
Published 2025-06-01“…These elements are vital for evaluating clinical interventions for lung cancer patients, predicting risks, and recognizing drug resistance. Moreover, we identified that pharmaceuticals facilitating copper ion transport (elesclomol and disulfiram), copper-chelating agents (DPEN, ATTM, and TETA), and nanoparticles engineered to transport copper are capable of effectively adjusting copper ion concentrations in lung cancer cells, subsequently inducing cuproptosis as a prospective treatment strategy for lung cancer. …”
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5752
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5753
Muscle Spatial Transcriptomic Reveals Heterogeneous Profiles in Juvenile Dermatomyositis and Persistence of Abnormal Signature After Remission
Published 2025-06-01“…This work paves the way for a better understanding of the pathophysiology in affected muscle and the identification of biomarkers that predict relapse.…”
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5754
Viable Approach of Tuning Oxide Semiconductor Thin Films in Solution‐Processed Heterojunction Thin Films Transistors for Both Higher Performances and Stability
Published 2025-02-01“…However, trap‐limited conduction becomes dominant in the bilayer with an excessively thick top layer, thereby leading to a significant reduction in mobility and positive bias stability. …”
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5755
Composite single-cell protein as a sustainable fishmeal substitute: Enhancing growth and health in largemouth bass (Micropterus salmoides)
Published 2025-07-01“…Functional predictions indicated enhanced pathways in “Cell motility” and “Immune system,” with enrichment of the NOD-like receptor signaling pathway. …”
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5756
Brazilian Morus nigra Attenuated Hyperglycemia, Dyslipidemia, and Prooxidant Status in Alloxan-Induced Diabetic Rats
Published 2017-01-01“…Acute EEMn treatment reduced hyperglycemia, improved oral glucose tolerance, and minimized dyslipidemia and oxidative stress leading to a reduction in atherogenic index in alloxan-induced diabetic rats.…”
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5757
Independent and Combined Associations of Urinary Heavy Metal Exposures with Serum α-Klotho in Middle-Aged and Older Adults
Published 2025-03-01“…Environmental metal exposure has been associated with oxidative stress and aging, but its effect on α-Klotho levels remains unclear. …”
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5758
Effect of legacy and emerging pollutants on genome-wide methylation patterns in black hake (Merluccius polli) natural populations
Published 2025-06-01“…Elevated Pb was significantly associated with a reduction in hake condition factor. Differentially methylated loci were associated with diverse pathways associated to responses for all pollutants (e.g. immune response, gene expression regulation), pointing to signs of stress within the population. …”
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5759
Study on Macroscopic and Microscopic Mechanical Behavior of Magnetorheological Elastomers by Representative Volume Element Approach
Published 2014-01-01“…Then by introducing the Maxwell stress tensor, a two-dimensional plane stress RVE for the MRE is developed in COMSOL Multiphysics to study its response under a magnetic field. …”
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5760
The impact of ride hailing on parking (and vice versa)
Published 2019-02-01“…This includes building a classification tree-based model to predict the replaced driving trips as a function of car ownership, destination land type, parking stress, and demographics. …”
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