The Pathophysiology of Vasovagal Syncope and New Approaches to its Pharmacological Treatment by Dalyia Abu-Ghazaleh MD, David A. Taylor PhD, Louise Roberts PhD, Indu Singh PhD, Vinicius Cruzat PhD, Roselyn B. Rose’Meyer PhD

“…Syncope refers to the transient loss of consciousness and the most common type of syncope is vasovagal syncope (VVS), usually occurring when a person is in an upright position, and/or after exposure to intense stress. The sequelae of VVS is caused by an increase in sympathetic tone and heart rate combined with an underfilled left ventricular chamber that leads to stimulation of cardiac afferent C fibers ultimately leading to bradycardia and vasodilation causing a reduction in venous return, cerebral hypoperfusion and VVS. …”
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Evaluating biocide efficacy in mixed-species biofilms: insights from a dual anaerobic biofilm reactor by Liam Jones, Niall Hanrahan, Maria Salta, Torben Lund Skovhus, Kathryn Thomas, Timothy Illson, Julian Wharton, Jeremy Webb

“…Each biocide application led to an electronegative shift in E corr and a reduction in $${{\rm{H}}}_{2}{\rm{S}}$$ H 2 S concentration, suggesting partial suppression of microbial activity. …”
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The alteration of neuronal activities of the cuneiform nucleus in non-hypovolemic and hypovolemic hypotensive conditions by Reza Mohebbati, Hassan Abbassian, Mohammad Naser Shafei, Ali Gorji, Sajad Sahab Negah

“…Abstract Background: The cuneiform nucleus is located in the center of the circuit that mediates autonomic responses to stress. Hemorrhagic hypotension leads to chemoreceptor anoxia, which consequently results in the reduction of baroreceptor discharge and stimulation of the chemoreceptor. …”
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The Influence of Overheating Temperature on the Shape Change of Primary Silicon Crystals and the Mechanical Properties of AlSi17 Alloy by K.K. Hillebrandt-Szymańska, J. Piątkowski

“…Such a structure, improving mechanical properties, increases the application area of hypereutectic Al-Si alloys, especially in the automotive and aerospace industries for heavily loaded castings operating under extreme thermal-mechanical stress conditions.…”
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Structural Condition Assessment and Temperature Effect Analysis of Cable–Pylon Anchorage Zone Using Long-Term SHM Data by Hanhui Ye, Zhijian Chen

“…By analysing the daily temperature effect on the upstream and downstream pylon walls, the regression model proposed in this study can be used to predict the daily temperature effect at any time in the diurnal cycle. …”
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Anti-ischemic and antiarrhythmic effectiveness of long-term bisoprolol therapy in patients with myocardial infarction by R. T. Shukurov, R. D. Kurbanov

“…Long-term B treatment was associated with a significant reduction in angina attack rate (by 3,9 times) and in the number of nitroglycerin tablets per week (by 4,3 times). …”
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Molecular Mechanisms of Druze Formation in the Retina in Age-Related Macular Degeneration by E. F. Barinov

“…They include the reactivation of lipid carriers in RPE cells, ligand-receptor mechanisms that provide a reduction pH in lysosomes and maintaining functional activity of macrophages.…”
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Role of SOST in Response to Mechanical Stimulation in Bone and Extraosseous Organs by Minyou Chen, Wenjing Li, Le Lei, Lingli Zhang

“…Prolonged exercise induces bone adaptation to mechanical stress, resulting in diminished responsiveness of bone cells to exercise and a reduction in serum SOST levels. …”
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Adaptive fractal dynamics: a time-varying Hurst approach to volatility modeling in equity markets by Abe Webb, Siddharth Mahajan, Mateo Sandhu, Rohan Agarwal, Arjun Velan

“…Empirical results indicate a 12.3 % reduction in RMSE and a 9.8 % improvement in MAPE, with an out-of-sample R-squared exceeding 0.72 compared to benchmark models. …”
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Shear strength, compressibility, and consolidation behaviour of expansive clay soil stabilized with lime and silica fume by Sultan Almuaythir, Muhammad Syamsul Imran Zaini, Muzamir Hasan

“…Experimental results indicate that the inclusion of silica fume and lime leads to a 35% increase in shear strength and a 28% reduction in compressibility compared to untreated soil. …”
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Sustainable Concrete Innovation: Crumb Rubber as a Partial Fine Aggregate Replacement by Santosh Kumar DAS, Amit SHIULY, Suchayan DINDA, Satish Kumar MAHATO

“…Additionally, durability tests reveal that rubberized concrete shows reduced chloride ion penetration and improved resistance to acid attack, with 30% reduction in chloride penetration at 15% rubber content. …”
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Research on 3D stability algorithm of spatial concave slope by Li Yin, Dong Wang, Xiaoyu Xing, Xiangyu Meng, Yiming Wu

“…Furthermore, there is an exponential correlation between the three - dimensional stability coefficient and the radius of curvature; specifically, as the radius increases, the coefficient decreases gradually, with its rate of reduction becoming milder over time. This study successfully addresses the issue of three - dimensional stability on concave slopes and offers more dependable theoretical approaches for mining engineering.…”
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Pollination and fruit formation in tomato culture in protected ground by Valentin G. Korol

“…Relevance The structure of the flowers of tomatoes is very thin adapted to self-pollination, and any violations of the technology of cultivation in protected ground lead to a significant reduction in the ability of plants to pollinate and fruit set. …”
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Polylactic acid-lauryl functionalized nanocellulose nanocomposites: Microstructural, thermo-mechanical and gas transport properties by D. Rigotti, R. Checchetto, S. Tarter, D. Caretti, M. Rizzuto, L. Fambri, A. Pegoretti

“…Concurrently, as LNC content increased, both elastic and storage moduli at room temperature exhibited a sharp decrease up to 5 wt% of filler, and a lower reduction for LCN concentration of 10–20 wt.%. Nanocomposites with 3 and 5 wt% of LNC showed the highest strain at break and a large amount of plastic deformation due to a strong interfacial adhesion between the PLA and filler particles. …”
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Development and Validation of Stability Indicating RP-HPLC Method for the Determination of Metaxalone in Bulk and its Pharmaceutical Formulations by Prafulla Kumar Sahu, M. Mathrusri Annapurna, Sahoo Dillip Kumar

“…The specificity of the proposed method was performed whereby metaxalone undergoes different stress conditions like oxidation, reduction, photolysis, acid and alkaline hydrolysis.…”
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Cerebral Vasospasm Pharmacological Treatment: An Update by Ioannis Siasios, Eftychia Z. Kapsalaki, Kostas N. Fountas

“…Aneurysmal subarachnoid hemorrhage- (aSAH-) associated vasospasm constitutes a clinicopathological entity, in which reversible vasculopathy, impaired autoregulatory function, and hypovolemia take place, and lead to the reduction of cerebral perfusion and finally ischemia. …”
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Features of nonalcoholic fatty liver disease pharmacotherapy in patients with overweight and obesity by K. V. Pivtorak

“…Some attempts are made to use drugs with different mechanisms of action and emphasize the reduction of laboratory and morphological signs of NAFLD activity. …”
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Torsional vibration analysis of the power transmission system in a hydraulic rail engineering vehicle by XU Kun, LUO Yaoxiang, ZHANG Yayu, LI Huawei

“…The introduction of a torsional damper lead to a significant reduction in the torsional vibration responses of the crankshaft. …”
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Thermal Analyses and Responses of Bridge Deck Hydronic Snow Melting System by Junjie Feng, Guansheng Yin

“…For both optimum snowmelt efficiency and thermal cracking reduction, the pipe embedded depth of 7 cm and pipe spacing of 10 cm are recommended for HSMP with the inlet fluid temperature of 15°C.…”
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The Interplay Between Melatonin and Nitric Oxide: Mechanisms and Implications in Stroke Pathophysiology by Santos Blanco, María del Mar Muñoz-Gallardo, Raquel Hernández, María Ángeles Peinado

“…Its key mechanisms related to NO include (1) differential modulation of nitric oxide synthase isoforms, suppressing detrimental iNOS expression/activity while often preserving or enhancing beneficial eNOS; (2) direct scavenging of NO and, critically, highly reactive peroxynitrite, thereby attenuating nitrosative stress; (3) reduction in neuroinflammation, partly by promoting M2 (anti-inflammatory) microglia polarization; and (4) mitochondrial protection and decreased apoptosis. …”
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