Contemporary view on the nature of deficient states in early age children by N. V. Banadyha

“…The daily excretion of copper in all surveyed was significantly lower compared to the control. Significant reduction in serum zinc was found in children with iron deficiency anemia (12.18 ± 0.34) mmol/l and the downward trend of zinc daily excretion of urine (341.11 ± 11.56) mg/day. …”
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Nutraceuticals for Age-Related Macular Degeneration: Formulation Optimization Focused on Safety by E. K. Pedanova

“…Age-related macular degeneration (AMD) is a multifactorial disease, with oxidative stress as a main pathogenetic factor in the development and progression. …”
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Characterisation of a peripheral neuropathic component of the rat monoiodoacetate model of osteoarthritis. by Matthew Thakur, Wahida Rahman, Carl Hobbs, Anthony H Dickenson, David L H Bennett

“…At the 7 day timepoint, ATF-3 signal was significantly smaller in 1 mg MIA treated animals than in the 2 mg treated group. 2 mg, but not 1 mg, intra-articular MIA was also associated with a significant reduction in intra-epidermal nerve fibre density in plantar hindpaw skin, and produced spinal cord dorsal and ventral horn microgliosis. …”
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EFFECT OF ETHYL METHANE SULPHONATE ON IMPROVING THE PHYSIOLOGICAL AND BIOCHEMICAL PROPERTIES OF TWO STRAWBERRY CULTIVARS by R. E. Y. AL-Hayali, S. I. Neamah

“…While the same cultivar Rubigim recorded the lowest significant reduction in H2O2 content at the two concentrations of 3.0% PEG and 3.0% EMS, which reached 0.540 µg g-1 FW. …”
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Land water availability altered by historical land use and land cover change by Tao Tang, Jun Ge, Junji Cao, Haiyun Shi

“…Here we show that historical LULCC caused an insignificant reduction in global P–ET, mainly in wet regions. Locally, P–ET tends to decrease (increase) in deforestation (reforestation) regions mainly due to the dominant role of precipitation. …”
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Survivability and behavior of probiotic bacteria encapsulated by internal gelation in non-dairy matrix and In Vitro GIT conditions. by Safdar Nazir, Muhammad Afzaal, Farhan Saeed, Aftab Ahmad, Huda Ateeq, Ali Ikram, Amara Rasheed, Faiza Kiran, Noor Akram, Faiyaz Ahmed, Aasma Asghar, Mahbubur Rahman Khan

“…Notably, encapsulated probiotics exhibited a decrease of 1.24 log CFU and 0.94 log CFU, while free cells experienced a reduction of 3.43 log CFU and 6.24 log CFU in mango juice over the storage period. …”
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Pathogenic effects of plasma thiols in patients with psoriasis on background of arterial hypertension by G. I. Makurina

“…During examination the patients with combined pathology of psoriasis and essential hypertension in the progressive phase of the disease revealed significant changes in glutathione systems and free-radical oxidation, characterized by a significantly decrease in the content of reduced glutathione (16,5±0,48 mmol/l) and increased content of oxidized glutathione (3,23±0,06 mol/l), while reducing the activity of the enzyme superoxide dismutase (24,21±1,44 conventional units /mg protein/min) and reduction ratio of the recovered / oxidized glutathione to 5,1±0,26 conventional units. …”
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P57 | SELONSERTIB (ASK1 INHIBITOR) IN SKIN TISSUE REPAIR OF OBESE MICE

“… Obesity can impair skin wound healing due to an increase in the oxidative stress that activates apoptosis signal-regulating kinase 1 (ASK1), an enzyme involved in cell death pathways. …”
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Trimetazidine in chronic heart failure patients aged above 75 years by I. V. Ignatenko, A. L. Pirogov, D. A. Altman, A. S. Prazdnov, N. K. Vereina

“…Results. Significant СHF PC reduction, physical stress tolerance increase, QoL and myocardial contractility improvement were registered in СHF patients aged above 75 years, with endothelial function improvement in intervention group. …”
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Evaluation of the Impact of Different Irrigation Deficit Treatments on the Yield, Yield Components, and Water Use Productivity of Autumn Wheat (Case Study: Shahrekord) by B. Naderi-Samani, M. Ghobadinia1, B. Haghighati, S.M.R. Hosseini-Vardanjani, A.R. Ahmadpour-Samani

“…Awareness of the impact of water deficit stress on the quantitative and qualitative performance of agricultural products, considering the recent recurrent droughts and reduced precipitation, is essential for water consumption management. …”
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Effect of dialysate glucose on synthesis of serum hepcidin in patients on maintenance hemodialysis by Hua Rui-xue, Zou Lu-xi, Wu Yu, Sun Ling

“…ObjectiveAs an important regulator of iron homeostasis，hepcidin participates in the pathophysiology of anemia and cardiovascular events in maintenance hemodialysis （MHD） patients.This study was designed to compare the effect of glucose-free versus glucose-containing dialysate on the synthesis of hepcidin-25 during hemodialysis （HD） and elucidate its potential mechanism in MHD patients.MethodsIn a self-before and after control study of 31 stable MHD non-diabetics，serum hepcidin-25 and plasma catecholamines （adrenaline，noradrenaline &amp; dopamine） were measured at pre-dialysis，intra-dialysis （120th min of HD） and post-dialysis using glucose-free dialysate and then switched to 5.5 mmol/L glucose-containing dialysate.One-way analysis of variance was utilized for identifying the effect of two dialysates on intra-dialysis%changes of serum hepcidin-25 and plasma catecholamines.Pearson/Spearman’s correlation coefficients were utilized for examining the relationships between serum hepcidin-25 and plasma catecholamines.ResultsGlucose-free dialysate achieved a greater reduction of serum hepcidin-25 than 5.5 mmol/L glucose-containing dialysate during a single HD ［（-8.45±18.46）% <italic>vs</italic> （0.37±17.24）%，<italic>P</italic>=0.0308］.Serum level of hepcidin-25 was positively associated with plasma levels of catecholamines at pre-，intra- and post-HD （<italic>r</italic>=0.34，0.25，0.62，<italic>P</italic>&lt;0.05）.ConclusionGlucose-containing dialysate may up-regulate hepcidin synthesis and/or secretion via an activation of sympathetic nervous system or oxidative stress，possibly due to elevated catecholamines.Adequately designed studies are still required for elucidating the mechanisms of dialysate glucose on hepcidin kinetics during HD.…”
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Herbo-Mineral Medicine, Cardiogrit Gold, Exhibits Protective Effects in Caenorhabditis elegans Model of Doxorubicin-Induced Cardiotoxicity by Acharya Balkrishna, Saurabh Bhatti, Meenu Tomer, Sudeep Verma, Rishabh Dev, Anurag Varshney

“…CG treatment rescued N2 C. elegans from doxorubicin-induced reduction in their growth, reproduction, locomotory behavior, pharyngeal pumping, feeding ability, and increased ROS generation. …”
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Rutin attenuates complete Freund’s adjuvant-induced inflammatory pain in rats by Fatemeh Forouzanfar, Ali Mohammad Pourbagher-Shahri, Amir Mahmoud Ahmadzadeh

“…Malondialdehyde (MDA), thiol levels, catalase, and superoxide dismutase (SOD) activities were also evaluated as serum oxidative stress markers. Results: Rutin and indomethacin significantly suppressed alterations in paw edema, pain responses, and arthritis scores and reduced the loss of body weight in contrast to disease-control rats. …”
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PHYSICAL ACTIVITY AND ITS IMPORTANCE FOR THE PREVENTION OF CARDIOVASCULAR DISEASES by S. S. Yakushin, E. V. Filippov

“…Further increase of the PA (its duration and/or intensity) leads to a further reduction of risks. PA should take most days of the week and have a duration of more than 10 minutes a day. …”
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Exploring the Mechanical Properties of Bioprinted Multi-Layered Polyvinyl Alcohol Cryogel for Vascular Applications by Argyro Panieraki, Nasim Mahmoodi, Carl Anthony, Rosemary J. Dyson, Lauren E. J. Thomas-Seale

“…Stress–strain curves exhibited nonlinear characteristics, better captured by quadratic (as opposed to linear) fitting, within the tested strain range (≤40%). …”
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Impact of Defects on the Low-Field Electron Mobility in GaN-on-Si HEMTs by Ran Zhou, D. J. Gravesteijn, R. J. E. Hueting

“…This suggests that the relatively high dislocation density in the GaN layer, which is a consequence of the still imperfect buffer layer in the GaN-on-Si substrate that is used to accommodate the strain difference, has an impact on <inline-formula> <tex-math notation="LaTeX">$N_{\textrm {it}}$ </tex-math></inline-formula>, thus subthreshold swing, in addition to the mobility reduction.…”
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AGE- MACULAR DEGENERATION AND GLAUCOMA. EPIDEMIOLOGICAL AND CLINIC-PATHOGENETIC ASPECTS by A. Z. Fursova, O. G. Gusarevich, M. S. Tarasov, M. A. Vasilyeva, N. V. Chubar, N. V. Litvinova

“…The vascular theory of pathogenesis related to the reduction of the perfusion of the head of the optic nerve, retina and chorioidea defines the diagnostic importance of the layer thickness parameters of the peripapillar nervous fibers and ganglion cell in differential diagnostics of this pathology. …”
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Numerical investigation of cooling enhancement in double-layer fractal-like microchannel disk heat sinks via layer shifting and tertiary channels by Hosein Akhtari, Ardalan Shafiei Ghazani

“…Angular shifting alone offers a modest reduction in thermal resistance; however, its combination with tertiary channels delivers substantial gains, significantly lowering thermal resistance. …”
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Development and Dynamic Numerical Evaluation of a Lightweight Sports Helmet Using Topology Optimization and Advanced Architected Materials by Nikolaos Kladovasilakis, Konstantinos Tsongas, Eleftheria Maria Pechlivani, Dimitrios Tzetzis

“…Hence, in the last decades, the scientific interest has been focused on establishing head injury criteria and improving the helmet design with the ultimate goal of the reduction in injury probability and increasing the athlete’s performance. …”
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Neuropharmacological effects of Gastrodia elata Blume and its active ingredients by Dong Wang, Dong Wang, Wei Liu, MeiJuan Lu, Qiang Xu

“…Modern research has demonstrated that GE and its active components exhibit neuropharmacological effects, including neuron protection, reduction of neurotoxicity, and promotion of nerve regeneration and survival. …”
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