Repurposing Rafoxanide: From Parasite Killer to Cancer Fighter by Teresa Pacifico, Lorenzo Tomassini, Livia Biancone, Giovanni Monteleone, Carmine Stolfi, Federica Laudisi

“…Preclinical studies in murine models have demonstrated significant reductions in tumor volume of up to 50% and a tumor-free rate exceeding 80%, with effective doses ranging from 7.5 to 40 mg/kg. …”
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Nutrient Availability Alters the Effect of Autophagy on Sulindac Sulfide-Induced Colon Cancer Cell Apoptosis by Shiun-Kwei Chiou, Neil Hoa, Lisheng Ge, Martin R. Jadus

“…Here, we show that inhibition of autophagy under serum-deprived conditions resulted in significant reductions of sulindac sulfide-induced apoptosis in HT-29 colon cancer cells. …”
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A comprehensive review of semantic web technologies supported life cycle management for road infrastructures by Rujie Zhang, Jianwei Wang, Haijiang Li, Xinhua Mao

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Emotional intelligence and its associated factors among case team leaders in health centers of East Gojam Zone, Northwest Ethiopia: an institutional based cross-sectional study by Endalew Minwuye Andargie, Seblewongel Gebretsadik Sertsewold, Tamiru Minwuye Andargie, Haimanot Wubale Tewabe, Asrat Kassaw, Yonas Fissha Adem, Wubshet D. Negash

“…Abstract Introduction Poor emotional intelligence (EI) among healthcare leaders resulted in ineffective communication and collaboration, misunderstandings and conflicts with team members, poor decision-making process, increased stress and burnout, reduced patient satisfaction and, decreased team performance. …”
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Prevalence of cardiovascular diseases and risk factor assessment in breast cancer survivors exposed to cardiotoxic therapy by Marina V. Vitsenya, Irina V. Barinova, Nana V. Pogosova, Tatevik A. Terteryan, David T. Kuchiev, Yulia V. Khrushcheva, Anna A. Gerasimova, Anastasiya Y. Filatova, Nursiyat M. Ibragimova, Olga O. Frolkova, Fail T. Ageev

“…The cardiorespiratory endurance was reduced, with median peak oxygen consumption being 71% of the predicted values. Anxiety symptoms were found in 45 (50%) patients, depressive symptoms in 16 (17.8%), high stress levels in 51 (56.7%), and sleep disorders in 80 (88.9%). …”
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Tumor Metastasis: Mechanistic Insights and Therapeutic Intervention by Lin Tang, Shao‐Cong Peng, Xiao‐Wan Zhuang, Yan He, Yu‐Xiang Song, Hao Nie, Can‐Can Zheng, Zhen‐Yu Pan, Alfred King‐Yin Lam, Ming‐Liang He, Xing‐Yuan Shi, Bin Li, Wen Wen Xu

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Coupled SWAT-MODFLOW model for assessing watershed responses to groundwater sustainability: A novel ensemble approach by Tarekegn Dejen Mengistu, Il-Moon Chung, Mingyu Kim, Sun Woo Chang

“…The performance of the integrated SWAT-MODFLOW model was assessed using the Parameter Estimation Tool (PEST) with streamflow and aquifer properties, and was found to be in reasonable agreement between the predicted and observed values. New hydrological insights: Annual ensemble values of exploitable amounts of groundwater discharge, minimum desirable flow, and groundwater recharge were used to compute the groundwater footprint and sustainability. …”
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Teaching and learning L2s in primary school

“…In conclusion, Babylonia 1/06 advocates for a comprehensive approach to foreign language instruction in primary education, highlighting the need for effective teaching strategies, supportive materials, and continuous professional development for educators. …”
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The impact of COVID-19 on young people's mental health, wellbeing and routine from a European perspective: A co-produced qualitative systematic review. by Lindsay H Dewa, Lily Roberts, Elizabeth Choong, Caroline Crandell, Ola Demkowicz, Emma Ashworth, Catia Branquinho, Steph Scott

“…Short-term impacts were related to the consequences of changing restrictions on social connection, day-to-day lifestyle, and education set-up. However, YP identified potential issues in these areas going forward, and therefore stressed the importance of ongoing long-term support in education, learning and mental health post-Covid-19.…”
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Spatial Platform for Periodontal Ligament Angulation and Regeneration: In Vivo Pilot Study by Min Guk Kim, Do-Yeon Kim, Hyoung-Gon Ko, Jin-Seok Byun, Joong-Hyun Kim, Chan Ho Park

“…The perio-complex scaffold exhibited predictable and controlled fibrous tissue alignment with specific angulations, ensuring spatial compartmentalization for PDL tissues and bone regenerations. …”
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Socio-ecological dynamics of Andean treelines in the 21st century by Gwendolyn Peyre, Enrique Zuñiga, Andrea Cornejo Paredes, Aremi Paja Medina, Jose Alfredo Sulla Torres, Manuel Zúñiga Carnero, Karina Rosas Paredes

“…This mini-review sheds light on the current state of Andean treelines today and suggests future pathways with anticipated opportunities for conservation and sustainable restoration. For instance, we stress the need for future research in species and community modelling to predict composition and distribution changes in forest and non-forest vegetation under global change scenarios.…”
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Numerical Simulation of the Effect of Pre-Strain on Fatigue Crack Growth in AA2024-T351 by Diogo M. Neto, Edmundo Sérgio, André Agra, Fernando V. Antunes

“…A numerical approach based on cumulative plastic strain at the crack tip was followed to predict FCG rate. The compressive pre-strain increased FCG rate, while the tensile pre-strain reduced the <i>da</i>/<i>dN</i> relative to the situation without pre-strain. …”
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Forecasting 3D Rupture Dynamics of the Alto Tiberina Low-Angle Normal Fault, Italy by Mathilde Marchandon, Alice-Agnes Gabriel, Lauro Chiaraluce, Elisa Tinti, Emanuele Casarotti, James Biemiller

“… The seismic potential of active low-angle normal faults (LANFs, <30° dip) remains enigmatic under Andersonian faulting theory, which predicts that normal faults dipping less than 30° should be inactive. …”
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Determinants of Behavioral Intention and Compliance Behavior Among Transportation Network Vehicle Service Drivers During the COVID-19 Pandemic by Ma. Janice J. Gumasing

“…In turn, behavioral intention strongly predicts compliance behavior (β = 0.643, <i>p</i> < 0.001), confirming its mediating role in linking influencing factors to actual adherence. …”
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Supporting student mental health while enhancing self-care: Evaluating the efficacy of a Graduate Teaching Assistant training module by Kristen A. Archbell, Kristin M. Brown

“…However, GTAs play dual roles as educators and students, who face their own stress and mental health challenges. …”
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Achieving excellent mechanical properties in CoNiCrMo multi-principal element alloys: A comprehensive approach integrating mean square atomic displacement and machine learning meth... by Yang Long, Wei Fang, Haoyang Yu, Tiexu Peng, Cong Li, Weiguang Liu, Chang Liu, Qinghe Jia, Yushui Chen, Jia Li, Fuxing Yin

“…The results indicate electronegativity difference is the descriptor of the highest importance in the lattice distortion prediction of the ML model. Meanwhile, the MSAD value is basically the same as the electronegativity difference value with compositional variation, which provides an important reference for alloy design. …”
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Monitoring the state of public health in the conditions of a full-scale war in Ukraine by O.M.

“…A change in a person’s health affects their quality of life, work productivity, the educational process, the mortality rate, and economic processes in general. …”
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The "Power Elite" and Environmental-Energy Policy in Japan by Iida Tetsunari, Andrew DeWit

“…They sought to persuade Kan and his government not to abandon the 2008 to 2012 Kyoto Protocol approach to securing carbon reductions via explicit and compulsory targets. Their concern was well grounded. …”
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Development of a wear coefficient equation for the A A7075-B4C composite – steel interface by Venkatrami Reddy Veduru, Ranjith R, Kanulla Karthik, P Sasirekha

“…The presence of reinforcement hinders dislocation movement led to an augmentation in the composites’ hardness, while an elevation in temperature resulted in a decline in hardness due to the reduction of Pierls stresses. Owing to the formation of a Mechanical Mixed Layer (MML), the wear rate decreases with addition of volume fraction of B _4 C particles until 7.5%, beyond this MML break down and wear rate transit from mild to severe due to the direct metal contact. …”
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Case Report: Phenotypic and genetic characterization of a presumptive sporadic hypothalamic hamartoma in a standard Schnauzer dog by Theofanis Liatis, Elizabeth Attree, Laura Ruiz De Alejos Blanco, Patrick Santens, Alberta De Stefani, Androniki Psifidi

“…These episodes could increase with stress or interaction, and the dog could not be distracted out of it. …”
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