Does change in neurotransmitter brain status affect the growth of transplantable melanoma? by O. I. Kit, E. M. Frantsiyants, V. A. Bandovkina, I. V. Kaplieva, E. I. Surikova, L. K. Trepitaki, N. D. Cheryarina, I. M. Kotieva

“…CNP in (+uPA) females resulted in the reduction of almost all studied biogenic amines (BA). …”
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Exploring the Shared Genetic Characteristics of Peri-Implantitis and Osteoporosis: A Transcriptomic Analysis Perspective by Churen Zhang, Feixiang Wang, Jianguo Ke, Cuihong Lin, Xiaohua Zeng, Qiuyan Yang, Qiaoling Cai

“…Potential drugs related to the hub genes were predicted using the Genecards database. Finally, the CIBERSORT core algorithm was used to calculate immune cell infiltration levels. …”
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Efficacy of Internet-based cognitive behavioral therapy for reducing perfectionistic strivings in the Republic of Korea: A randomized controlled trial by Sanghoon Oh, Jeong hee Cha, Jungwon Joo, Ji Hyung Lee, Yunna Lee, Hyung Jun Lee, Dong Uk Yoon, Jeonghwan Lee

“…Compared to the control group, the ICBT group showed significant reductions in perfectionistic strivings (FMPS Concern over Mistakes: d = −0.65, 95 % CI [−1.05, −0.25]), anxiety (GAD-7: d = −0.42, 95 % CI [−0.83, −0.01]), and increased life satisfaction (SWLS: d = 0.62, 95 % CI [0.20, 1.03]). …”
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Antioxidant, anti-glycation and hypoglycemic potentials of Acmella uliginosa: A probable candidate for the amelioration of diabetes mellitus by Mahfuza Akter, Faria Farzana Perveen, Noore Zannat Nuren, Nasim Ahmed, Md. Ataur Rahman, Md. Masum Billah, Md. Abdul Bari, Sabbir Ahmed, Md. Nurul Islam

“…In vivo studies confirmed the antidiabetic potential of both extracts, with significant reductions in blood glucose levels in OGTT and hypoglycemic tests. …”
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Genome-wide identification and integrated analysis of the WNK kinase gene family and expression analysis of PgWNK genes under methyl jasmonate treatment in Panax ginseng by Kexin Zhang, Aimin Wang, Lin Shi, Jiaqing Liu, Yu Zhang, Yang Jiang, Meiping Zhang, Yi Wang, Mingzhu Zhao, Kangyu Wang

“…In addition, 17 non-biological stress response components related to hormone response, growth, and development were predicted in the promoter area of the PgWNK gene. …”
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Proximal Effects of a Just-in-Time Adaptive Intervention for Smoking Cessation With Wearable Sensors: Microrandomized Trial by Christine Vinci, Steve K Sutton, Min-Jeong Yang, Sarah R Jones, Santosh Kumar, David W Wetter

“…Increases in abstinence self-efficacy significantly predicted abstinence. ConclusionsTo our knowledge, this is the first study to test the proximal impact of a mindfulness-based JITAI on key variables associated with smoking cessation. …”
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Experimental Study on Compressive Capacity Behavior of Helical Anchors in Aeolian Sand and Optimization of Design Methods by Qingsheng Chen, Wei Liu, Linhe Li, Yijin Wu, Yi Zhang, Songzhao Qu, Yue Zhang, Fei Liu, Yonghua Guo

“…The compressive capacity of helical anchors constitutes a pivotal performance parameter in geotechnical design. To precisely predict the compressive bearing behavior of helical anchors in aeolian sand, this study integrates in situ testing with finite element numerical analysis to systematically elucidate the non-linear evolution of its load-bearing mechanisms. …”
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Profiling disease experience in patients living with brain aneurysms by analyzing multimodal clinical data and quality of life measures by Sebastian R. Reder, Jochen Hardt, Marc A. Brockmann, Carolin Brockmann, Suam Kim, Melina Kawulycz, Marie Schulz, Sven Rainer Kantelhardt, Katja Petrowski, Sabine Fischbeck

“…In regression analyses, the DW was predictable by PH (β = 0.345) and MH (β=-0.646; R = 0.557; p < 0.001). …”
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Examining sleep health and its associations with technology use among older adults in Sweden: insights from a population-based study by Sarah Nauman Ghazi, Anders Behrens, Johan Sanmartin Berglund, Jessica Berner, Peter Anderberg

“…DSP was found to be a predictor of better satisfaction (OR: 1.32, $$p= 0.009$$ ), efficiency (OR: 1.16, $$p=0.026$$ ), and duration of sleep (OR:1.16, $$p= 0.042$$ ). Lower TA predicted better satisfaction (OR: 0.81, $$p=0.04$$ ), timing (OR: 0.74, $$p=0.04$$ ), and efficiency (OR:0.78, $$p=0.01$$ ) of sleep. …”
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Dehydroepiandrosterone and cognitive impairment and impact in cardiovascular mortality among men and women 55 years and older by S. A. Shalnova, N. A. Imaeva, A. E. Imaeva, V. A. Kutsenko, Yu. A. Balanova, A. V. Kapustina, O. M. Drapkina

“…The present study was carried out as part of the prospective cohort survey "Stress, aging and health" in Russia. 1876 men and women aged 55 years and older were examined. …”
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Planetary Gearbox Design and Development using Additive Manufacturing by Mohammed Amer, Chung-Cheng Lin, Hasan Ismail, Shin-Hung Wu, Bo-Rong Lu, Zhang-Yang Wu, Shih-Feng Chen, Chung-Wei Cheng

“…The printed model performed exceptionally well when it came to performance, and it can be used for both educational and industrial purposes, exhibiting the ability to withstand a high level of stress. …”
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Toward optimizing new nurse anaesthetist training: a qualitative study of perceptions, experiences, and systemic challenges by Tingting Yang, Xueyan Xing, Ying Sun, Jiale Hu, Jiamin Kang, Shumin Tu

“…Methods Semi-structured interviews were performed with a purposive sample of 14 participants, comprising junior nurse anaesthetists, anaesthesiologists educators, administrators, and anaesthesia nursing educators, administrators. …”
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Damage effect of combined noise and CO exposure on spermatogenesis in male rats by GUO Lulu, ZHANG Zhonghao, LIU Chang

“…Results‍　‍Compared with the negative control group, the combined exposure group exhibited significant reductions in sperm viability and count (P<0.05), and developmental arrest of immature germ cells in the testicular tissue, with obviously less spermatogonia, spermatocytes, and round/elongated spermatids (P<0.01). …”
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Ectomycorrhizal fungal community succession and fragmentation across forest edges nearly three decades postharvest by Olivia M. Rianhard, J. Marty Kranabetter, Latina V. Penkova, Daniel M. Durall, Melanie D. Jones

“…We tested this premise by examining ectomycorrhizal fungal communities across forest edges in 1‐ha openings at nearly three decades postharvest. We found reductions in species richness and shifts in community composition were still evident, illustrating how recovery was limited by the open canopies of younger trees. …”
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Pelvic Floor Health and Urinary Incontinence in Female Soccer Players: A Comparative Analysis Between Professionals and Physically Active Women: A Cross-Sectional Descriptive Proto... by Julia M. Sebastian-Rico, María Jesús Muñoz-Fernández, Luis Manuel Martínez-Aranda, África Calvo-Lluch, Manuel Ortega-Becerra

“…<b>Results:</b> UI affected 35.7% of physically active women and 50% of professional soccer players. Stress urinary incontinence (SUI) was the most common type, present in 100% of affected soccer players and 60% of affected active women. …”
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A brief history of high-stakes testing and its possible futures by María Jesús Gutiérrez Domínguez

“…Through a Systematic Literature Review (SLR), the present study develops a global examination of this mechanism, in order to understand its scope and influence on the educational system. The results reveal both adverse and beneficial outcomes of high-stakes testing and, while the literature highlights unintended consequences, it also stresses the importance of its function as an accountability mechanism in the current society, implying positive aspects. …”
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Nursing Shortage in Pakistan: A Looming Crisis by Fawad Mueen Arbi, Mahnoor Baloch, Shahid Ullah Khan

“…Overworked nurses are at risk of burnout, which can compromise patient safety and the quality of care provided.4 Longer working hours and increased stress levels among nurses also contribute to higher attrition rates, exacerbating the problem. …”
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Lactylation-mediated miRNA regulation in cancer therapy resistance by Yiyi Shou, Ruiqi Liu, Hao Xiong, Xiaoyan Chen, Luanluan Huang, Ran Huang, Hailong Sheng, Haibo Zhang, Yanwei Lu, Haiwei Guo

“…Based on these converging mechanisms, we highlight potential therapeutic strategies, including the co-targeting of LDHA and oncogenic miRNAs (e.g., nanoparticle-mediated delivery of anti-miR-21), as well as liquid biopsy-based monitoring of circulating H3K18la and miRNA signatures to predict emerging resistance. By integrating metabolic, epigenetic, and immunologic perspectives, we position lactylation-miRNA crosstalk as a central regulatory axis in cancer therapy resistance and offer a conceptual framework to inform the development of future mechanism-driven interventions.…”
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Gut microbiota remodeling exacerbates neuroinflammation and cognitive dysfunction via the microbiota-gut-brain axis in prenatal VPA-exposed C57BL/6 mice offspring by Zhaoming Liu, Zhaoming Liu, Caixia Wu, Caixia Wu, Zhaojian Sun, Zuoxian Lin, Yirong Sun, Nouman Amjad, Muhammad Majid, Rajesh Basnet, Zhiyuan Li, Zhiyuan Li, Zhiyuan Li

“…Gut microbiota profiles were analyzed via 16S rRNA sequencing, with functional pathway predictions using PICRUSt2 and KEGG databases.ResultsVPA-exposed mice exhibited ASD-like behaviors, including social deficits, repetitive stereotypic actions, and impaired spatial memory. …”
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A clinical case of diagnosis of autoimmune hepatitis at the stage of liver cirrhosis by O. A. Svitlytska, O. V. Riabokon, A. O. Svitlytskyі, N. H. Horbatkova, E. V. Kotliarevska

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