An adverse outcome pathway for cigarette smoke-mediated oxidative stress in plaque formation by Patrudu Makena, Linsey E. Haswell, Michael McEwan, Brian M. Keyser, David E. Smart, Robert Leverette, Kristen Jordan, Damien Breheny, Sarah Baxter-Wright

“…The AOP framework provides a system to make predictions and assessments while reducing the need for in vivo assessment. …”
Get full text

Molecular regulation of chronic stress responses in European sea bass, Dicentrarchus labrax by Athanasios Samaras, Spyridon Kollias, Spyridon Kollias, Michail Pavlidis

“…IntroductionThis study examines the effects of predictable repeated chronic stress on the stress response and cortisol metabolism in European sea bass.MethodsFish were exposed to daily stress for 11 days and sampled the next day before or after an additional stressor. …”
Get full text

Adaptive variation regulates the expression of the human SGK1 gene in response to stress. by Francesca Luca, Sonal Kashyap, Catherine Southard, Min Zou, David Witonsky, Anna Di Rienzo, Suzanne D Conzen

“…The Serum and Glucocorticoid-regulated Kinase1 (SGK1) gene is a target of the glucocorticoid receptor (GR) and is central to the stress response in many human tissues. Because environmental stress varies across habitats, we hypothesized that natural selection shaped the geographic distribution of genetic variants regulating the level of SGK1 expression following GR activation. …”
Get full text

Inversion of multiphase tectonic stress field and fracture evolution in shale gas reservoirs by WANG Jiawei, ZHANG Bohu, HU Yao, HE Zhengyi, HU Xinxin, CHEN Wei, LUO Chao

“…Additionally, neural network algorithms and geological mechanics modeling analysis have been used to invert the stress field of ancient geological structures across multiple stages within the study area and to predict the development of reservoir fractures influenced by stress. …”
Get full text

Investigating lightweight and interpretable machine learning models for efficient and explainable stress detection by Debasish Ghose, Ayan Chatterjee, Indika A. M. Balapuwaduge, Yuan Lin, Soumya P. Dash

“…Stress is a common human reaction to demanding circumstances, and prolonged and excessive stress can have detrimental effects on both mental and physical health. …”
Get full text

Identification of <i>SNAT</i> Gene Family and Their Response to Abiotic Stress in Citrus by Qian Yao, Mingzhou Gu, Chengyang Song, Lijuan Jiang, Lun Wang, Xiaoyong Xu

“…Additionally, the tissue-specific expression of trifoliate orange SNAT family members and their expression patterns under stress conditions were examined. This study identified 21 members of the <i>SNAT</i> gene family across five citrus genomes, distributed over five chromosomes, with the majority predicted to localize within chloroplasts. …”
Get full text

Distinguishing neural ensembles in the infralimbic cortex that regulate stress vulnerability and coping behavior by Jenna L. Laymon, Conner J. Whitten, Anna F. Radford, Alonnah R. Brewer, Yash S. Deo, Mackenzie K. Hooker, Akhil A. Geddati, Matthew A. Cooper

“…Overall, these findings suggest that activation of IL PV cells during social defeat predicts the development stress vulnerability in males, whereas activation of IL neurons is associated with a proactive response to social defeat exposure in females. …”
Get full text

Inversion model of stress state reconstruction for geological hazard pipelines based on digital twin by Xue Luning, Tian Mingliang, Zhao Juncheng

“…To improve the real-time and prediction accuracy of underground pipeline stress monitoring in the context of geohazards, the study constructs a dynamic closed-loop pipeline stress state reconstruction and inversion framework based on digital twin technology. …”
Get full text

Highland barley ELNs and physiological responses to different concentrations of Cr (VI) stress by Ajia Sha, Bingliang Liu, Changying Liu, Qizhong Sun, Mingxing Chen, Lianxin Peng, Liang Zou, Changsong Zhao, Qiang Li

“…Out of these, 25 were newly predicted miRNAs, and the remaining four were known miRNAs. …”
Get full text

Global projections of heat stress at high temporal resolution using machine learning by P. Georgiades, P. Georgiades, T. Economou, T. Economou, Y. Proestos, J. Araya, J. Lelieveld, J. Lelieveld, M. Neira

“…These high-resolution THI data provide an accurate quantification of heat stress in dairy cattle, enabling improved predictions and management strategies to mitigate the impacts of climate change on this vital agricultural sector. …”
Get full text

The intersection of stress, loneliness, and mental health attitudes in young multinational corporation employees by Thuy Thi Thanh LE, Ha-Chau TRAN-NGOC, Van-Nhi HO, Bao-Nhu NGUYEN-HOANG, Hoang-Anh Ngoc HO, Van-Anh TRAN-DO

“…PLS-SEM revealed that perceived stress significantly predicted dissatisfaction with social relationships (β = 0.408, p < 0.001), which was strongly associated with PIU (β = 0.407, p < 0.001), indicating a maladaptive coping mechanism. …”
Get full text

Peculiarities of Inflammation, Oxidative/Nitrosative Stress in L-Ornithine-Induced Acute Pancreatitis by Chooklin S., Chuklin S., Shershen G.

“…However, despite the progress in understanding early events in AP, addi­ tional research is needed to quickly and accurately predict the severe course of the disease, as well as more specif­ ic and purposeful treatment. …”
Get full text

Strike at the root: exploring the transferability of heat stress tolerance in tomatoes by reciprocal grafting by Robin T. Biermann, Robin T. Biermann, Linh T. Bach, Christian M. Steuer, Christian M. Steuer, Julia J. Reimer, Dietmar Schwarz, Frederik Börnke, Frederik Börnke

“…However, more sophisticated screening techniques might be needed to successfully predict stress alleviation by grafting pair selection. …”
Get full text

Impact of Epidural Analgesia on Hemodynamics and Stress Markers in Children during Orthopedic Surgery by V. I. Ledyaikin, N. A. Pyatayev

“…Objective: to study the specific features of systemic hemodynamics and stress markers in young (1—5-year-old) and old (6—12-year-old) children during orthopedic surgery under intra- and postoperative epidural analgesia. …”
Get full text

Exploring the Anxiolytic, Antidepressant, and Immunomodulatory Effects of Cannabidiol in Acute Stress Rat Models by Hristina Zlatanova-Tenisheva, Maria Georgieva-Kotetarova, Natalia Vilmosh, Ilin Kandilarov, Delyan Delev, Tihomir Dermendzhiev, Ilia Dimitrov Kostadinov

“…However, existing data are inconsistent, likely due to variations in experimental designs, dosages, and stress models. This study sought to assess the impact of CBD on anxiety and depression-like behaviors in Wistar rats exposed to acute cold stress, as well as its impact on pro- and anti-inflammatory cytokines. …”
Get full text

DNA replication stress underpins the vulnerability to oxidative phosphorylation inhibition in colorectal cancer by Xiao Hong Zhao, Man Man Han, Qian Qian Yan, Yi Meng Yue, Kaihong Ye, Yuan Yuan Zhang, Liu Teng, Liang Xu, Xiao-Jing Shi, Ting La, Yu Chen Feng, Ran Xu, Vinod K. Narayana, David P. De Souza, Lake-Ee Quek, Jeff Holst, Tao Liu, Mark A. Baker, Rick F. Thorne, Xu Dong Zhang, Lei Jin

“…This shortage in aspartate, in turn, caused nucleotide deficiencies, leading to S phase cell cycle arrest, replication fork stalling, and enrichment of the p53 pathway, manifestations of replication stress. The addition of purine nucleobases adenine and guanine along with the pyrimidine nucleoside uridine restored replication fork progression and cell proliferation, whereas the supplementation of exogenous aspartate recovered the nucleotide pool, demonstrating a causal role of the aspartate shortage in OXPHOS inhibition-induced nucleotide deficiencies and consequently replication stress and reductions in proliferation. …”
Get full text

Economic stress from climate change on agriculture: a SAM-based assessment by Watchara Pechdin, Pongsun Bunditsakulchai

Get full text

Autonomic and physiological stress responses in navy divers: the protective role of diving experience by Yu-Ju Chen, Yuan-Sheng Tzeng, Yuan-Sheng Tzeng, Shih-En Tang, Shih-En Tang, Chi-Rong Li, Shu-Yu Wu, Kun-Lun Huang, Kun-Lun Huang

“…Heart rate variability (HRV), including linear (rMSSD, HF) and non-linear indices (SD1, SD1/SD2, sample entropy), was measured at four dive stages (pre-dive, bottom, decompression, and post-dive).ResultsAfter adjusting for age and perceived stress, experienced divers exhibited greater post-dive reductions in cortisol (p = 0.015) and amylase (p = 0.022). …”
Get full text

Genetic effects of physiological and morpho-agronomic traits in popcorn under water stress by Marcelo VIVAS, Lauro Jos&#x00E9; Moreira GUIMAR&#x00C3;ES, Monique DE SOUZA SANTOS, Eliemar CAMPOSTRINI, Fl&#x00E1;via Nic&#x00E1;cio VIANA, U&#x00E9;liton Alves DE OLIVEIRA, Carolina Macedo CARVALHO, Talles de Oliveira SANTOS, Rosimeire BARBOZA BISPO, Samuel Henrique KAMPHORST, Ant&#x00F4;nio Teixeira do AMARAL JUNIOR, Valter J&#x00E1;rio DE LIMA

“…Significant genetic variability was observed, with reductions in grain mass and popping expansion under water stress. …”
Get full text

Understanding the Impact of Salt Stress on Plant Pathogens Through Phenotypic and Transcriptomic Analysis by Hyejung Jung, Gil Han, Duyoung Lee, Hyun-Kyoung Jung, Young-Sam Kim, Hee Jeong Kong, Young-Ok Kim, Young-Su Seo, Jungwook Park

“…Phenotypic assays revealed that <i>B. gladioli</i> and <i>R. solanacearum</i> are highly sensitive to salt stress, exhibiting significant reductions in growth, motility, and enzyme production, whereas <i>Pcc</i> showed notable tolerance. …”
Get full text