Double vulnerability of active-NRF2 lung squamous cell carcinoma to NRF2 and TRIM24 by Miriam Sánchez-Ortega, Antonio Garrido, Lorena Sanz, Rafael Torres-Pérez, Carmen Hernandez, Alvaro Gutierrez-Uzquiza, Ming Sound Tsao, Ana Clara Carrera

“…Although normal-NRF2 cells are more sensitive to oxidative stress, they do not require NRF2 for survival under non-stress conditions, in contrast, LUSC cells with active-NRF2 mutations depend on NRF2 for viability. …”
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A Dashboard for Managing an Ecosystem and People With Dementia: Protocol for a Healthy Ageing Ecosystem for People With Dementia (HAAL) International Feasibility Pilot Study by Giulio Amabili, Elvira Maranesi, Federico Barbarossa, Arianna Margaritini, Anna Rita Bonfigli, Fong-Chin Su, Chien-Ju Lin, Hsiao-Feng Chieh, Dianne Vasseur, Henk Herman Nap, Yeh-Liang Hsu, Dorothy Bai, Roberta Bevilacqua

“…ConclusionsThe HAAL pilot study was an innovative feasibility study whose primary objectives were to assess reduction in care load for FCs, stress relief for FCs and ICs, and improvement in the perceived quality of life for ICs and people with dementia. …”
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Nanoparticles from grape seed extract inhibit inflammatory cytokines and ameliorate CCl4-induced hepatotoxicity by Neveen Adel Madbouly, Doaa Mohammad Ali, Alyaa Ahmed Farid

“…Conversely, GS extract NPs supplementation potentially ameliorate hepatic functions by normalization of serum ALT, AST and ALP, reduced MDA level, improved antioxidant CAT, regulated liver inflammatory cytokines via maximal reduction of hepatic IL-1β, IL-4, IL-6 and TNF-α. Conclusion GS extract NPs augmented the antioxidant and anti-inflammatory properties of GS extract thereby protecting the liver against oxidative stress induced by CCl4 as hepatic xenobiotic. …”
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Mobile-Based Cognitive Behavioral Therapy for Health Care Workers’ Mental Health in Ecuador: Quasi-Experimental Study by Sandra Lorena Muñoz-Ortega, Rubén Vladimir Alvarado Muñoz, Daniela Santamaria Guayaquil, Jade Pluas-Borja, Marco Faytong-Haro

“… Abstract BackgroundMental health challenges, including depression, anxiety, and burnout, have become increasingly prevalent among health care workers, who face high-stress environments, limited resources, and long working hours. …”
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Full-scale fatigue test and properties of low shrinkage LUHPC-steel composite bridge deck by Xiaoting Song, Baichuan Li, Jun Fu, Zheshi Wang, Qingjun Ding

“…The results also showed that despite a marginal 2.56 % increase in weight and a 6.32 % rise in cost, the new pavement scheme experienced a significant reduction of 27.6 % in the peak tensile stress compared to the original pavement scheme, thereby improving the bridge deck’s fatigue performance. …”
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 Electrokinetic blood flow of Carreau ternary nanofluids in stenotic arteries with thermal reactions under CC heat flux for therapy by Saima Riasat, Saira Iqbal, Sadia Hina, Kaouther Ghachem, Aboulbaba Eladeb, Walid Hassen, Lioua Kolsi

“…The main results indicate that the increase of the zeta potential (electrokinetic effect) causes a substantial reduction of the wall shear stress, which lowers energy losses and improves overall blood flow efficiency. …”
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A software tool and strategy for peptidoglycomics, the high-resolution analysis of bacterial peptidoglycans via LC-MS/MS by Marcel G. Alamán-Zárate, Brooks J. Rady, Raphael Ledermann, Neil Shephard, Caroline A. Evans, Mark J. Dickman, Robert D. Turner, Aline Rifflet, Ankur V. Patel, Ivo Gomperts Boneca, Philip S. Poole, Marshall Bern, Stéphane Mesnage

“…Here we describe user-friendly open-source tools and a web interface for building peptidoglycan databases, performing MS searches, and predicting the MS/MS fragmentation of muropeptides. …”
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Drought adaptation index (DAI) based on BLUP as a selection approach for drought-resilient switchgrass germplasm by Shiva Om Makaju, Shiva Om Makaju, Shiva Om Makaju, Hari Bahadur Chhetri, Chanaka Roshan Abeyratne, Mirko Pavicic, Hari Poudel, Jazib Ali Irfan, Jazib Ali Irfan, Anita Giabardo, Katrien M. Devos, Katrien M. Devos, Katrien M. Devos, Daniel Jacobson, Ali Mekki Missaoui, Ali Mekki Missaoui, Ali Mekki Missaoui

“…This study introduces a Drought Adaptation Index (DAI), derived from Best Linear Unbiased Prediction (BLUP), as a method to assess drought resilience in switchgrass (Panicum virgatum L.). …”
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Numerical modelling of tsunami-induced scour around a coastal dike by Ravindra Jayaratne, Adewale Abimbola, Nilakshan Balasubramaniam, Mohammad Tabasi

“…The results indicated good agreement with the predicted scour depths which were associated with the hydraulic conditions, sediment characteristics, and structure geometry. …”
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Two-stage cultivation of microalga for sustainable biofuel production by Gyanendra Tripathi, Priyanka Dubey, Khwaja Osama, Suahil Ahmad, Irum, Veer Singh, Alvina Farooqui, Emanuel Vamanu, Sachchida Nand Rai, Vishal Mishra

“…A support vector regression (SVR) model was used to develop the predictive model to predict the cell biomass on a dry basis at different culture conditions. …”
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Comparison of Atmospheric O₃ Dose–Response Effects Under N Addition on Gas Exchange, Growth, and Biomass of <i>Raphanus sativus</i> L. by Li Li, Jinling Li

“…In conclusion, N addition can alleviate O₃-induced reductions in Pn and biomass via non-stomatal mechanisms, but it is ineffective in altering long-term O₃ dose–response relationships. …”
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Thought Beyond the Inkblots: One-Year Follow-Up in a Cohort of Italian Adolescents with Psychotic Symptoms by Adelaide Carrara, Marzia Di Girolamo, Melanie Iorio, Arianna Vecchio, Luciano Giromini, Renato Borgatti, Martina Maria Mensi, Marika Orlandi

“…Methods: We enrolled 151 patients to assess the potential of the Rorschach Performance Assessment System (R-PAS) in predicting the course of CHR-P and transitions to psychosis. …”
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Investigating the prevalence of halitosis and its associated factors amongst the general population of Karachi, Pakistan by Warisha Tul Islam, Anisa Azhar, Tehniat Faraz Ahmed, Amynah Charania Shaikh

“…Symptoms of gastroesophageal reflux disease, sinusitis, asthma, diabetes, hypertension and mental stress were associated with halitosis (p<0.05). Higher monthly household income and daily use of dental floss predicted lower odds of halitosis (p<0.05). …”
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Toxicological Effects of Combined Exposure of Cadmium and Enrofloxacin on Zebrafish by Lingfei Ren, Yu He, Chao Hou, Chaoxuan Liao, Miao Chen

“…Chronic exposure revealed that ENR enhanced Cd accumulation in the liver, intestine, and muscle tissues by 1.11–2.33-fold compared to single Cd exposure. Oxidative stress markers showed dynamic temporal changes, with superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), and catalase (CAT) activities initially increasing by 1.34–7.06-fold, 0.98–3.28-fold, and 1.53–3.65-fold at 8 d, respectively, followed by 9.9–48.98% reductions after 20 d of exposure. …”
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Finite element analysis of the modified intramedullary nail-II for managing reverse obliquity trochanteric fractures by Qian Wang, Yao Lu, Lu Liu, Teng Ma, Zhong Li, Kun Zhang, Qiang Huang

“…In comparison with the PFNA group, the MIN-II group showed a 30.0% reduction in 31-A3.1 ROT fracture and a 20.2% reduction in 31-A3.3 ROT fracture for this indicator, respectively. …”
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Combined Effects of Flood Disturbances and Nutrient Enrichment Prompt Aquatic Vegetation Expansion: Sediment Evidence from a Floodplain Lake by Zhuoxuan Gu, Yan Li, Jingxiang Li, Zixin Liu, Yingying Chen, Yajing Wang, Erik Jeppesen, Xuhui Dong

“…Therefore, understanding aquatic macrophyte responses to flood disturbances and nutrient enrichment is crucial for predicting future vegetation dynamics in lake ecosystems. …”
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FRACTALS IN GEOLOGY, GEOTECTONIC AND GEODYNAMIC ASPECTS by V. M. Kharchenko, D. V. Lapta

“…Conclusions: as a result of the conducted studies, it was revealed that SCTs are a clear example of geological fractals, the interpretation of which proved the possibility of searching for mineral deposits, including oil and gas, predicting natural anomalous phenomena, environmental conditions and seismicity of territories of different scales.…”
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To share or hide under performance pressure: the role of supervisor support in shaping subordinate knowledge management behaviors by Jia Xu, Jia Xu, Jingrong Chen, Qisi Lan, Man Zhao

“…Both methods assessed the interaction between performance pressure and perceived supervisor support in predicting knowledge sharing and hiding behaviors.ResultsFindings revealed two distinct paths. …”
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Impact of Tetrahydropyrido[2,1-b][1,3,5]thiadiazines on L-DOPA Effects in the Tail Suspension Test by E. Yu. Bibik, I. A. Nekrasa, A. V. Demenko, K. A. Frolov, V. V. Dotsenko, S. G. Krivokolysko, A. S. Startseva

“…Administration of levodopa at a dose of 150 mg/kg led to a reduction in rectal temperature and the total time of physical activity in rats in the tail suspension test. …”
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Insulin Therapy to Control Hyperglycemia in Diabetic Patients With Ischemic Stroke: A Comparative of Intravenous and Subcutaneous Injection by Seyyed Mahdi Zia Ziabari, Behrang Motamed, Babak Bakhshayesh Eghbali, Nazanin Noori Roodsari, Yasman Kamiar, Ashkan Asgari Gesht Rudkhani, Mohammad Ali Yazdanipour

“…Background The stress hyperglycemia is different from diabetes and is common after an acute illness such as stroke.  …”
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