PHONETIC REHABILITATION FOR REMOVABLE DENTAL PROSTHETICS by M. Nidzelsky, V. Chikor, N. Tsvetkova

“…The appearance of improper pronunciation of sounds is considered as a result of motor and sensory disorders of the central or peripheral nature: changes in the structure of the articulation apparatus and violations of muscle inertia involved in articulation; reduction of peripheral hearing and violations of the auditory perception of the central character. …”
Get full text

A New Model of Bone Remodelling by Justyna MIODOWSKA, Jan BIELSKI, Magdalena KROMKA-SZYDEK

“…The created model is used to predict the stress-stimulated change in callus density. …”
Get full text

The elucidation of the dual role of Beclin-1 in ischemic stroke through systems biology modeling by Jun Seok Cha, Jinyoung Kim, Junyoung Cho, Jungho Lee, Jiyoon Kim, Dongwoo Chae

“…We developed a mathematical model incorporating the dual role of Beclin-1 to simulate Beclin-1-induced autophagy and apoptosis under varying ischemic stress conditions. The model predicts a critical threshold of Beclin-1 expression, beyond which apoptosis is triggered, with this threshold decreasing as stress severity increases. …”
Get full text

Ultimate load analysis of casings in slip-working sections of underground gas storage wells by Yuxian He, Haiyun Ma, Lin Chen, Hangming Liu, Jifang Wan, Xianzhong Yi

“…The results indicate that the Tresca criterion predicts a 15.7% lower ultimate load than the von Mises criterion, providing a safer UGS casing strength assessment. …”
Get full text

Finite Element Model-Based Weight-Over Process Philosophy for Bridge Loading Capacity Evaluation and Rating Factor Estimation by Ali Karimpour, Salam Rahmatalla, Hossein Bolboli Ghadikolaee

“…In these methods, uniaxial yielding stress is traditionally used to detect component capacity using either stress quantities or shear-moment actions to compute the capacity demand of the bridge. …”
Get full text

Investigation of Emotional Intelligence in Medical Students at Babol University of Medical Sciences Based on the Bar-On Questionnaire by Mohamad Vahdat-lasemi, Mahjoobeh Betyar, Maryam Ghaemi-Amiri

“…Background and Objective: Emotional skills and abilities, commonly known as emotional intelligence, predict individuals' success in life and their ability to cope with stress. …”
Get full text

Impaired DNAJB2 Response to Heat Shock in Fibroblasts from a Neuropathy Patient with <i>DNAJB2/HSJ1</i> Mutation: Cystamine as a Potential Therapeutic Intervention by Raj Kumar Pradhan, Nikolas G. Kinney, Brigid K. Jensen, Hristelina Ilieva

“…While homozygous mutations in DNAJB2/HSJ1 have been linked to early-onset neuropathy, a heterozygous DNAJB2 c.823+6C>T was discovered in an adult patient with severe sensory–motor polyneuropathy. This mutation is predicted to affect both isoforms of the protein. DNAJB2 (HSP40), a key member of the heat shock protein family, plays a critical role in cellular protection and stress, including response to heat shock. …”
Get full text

Autocrine interferon poisoning mediates ADAR1-dependent synthetic lethality in BRCA1/2-mutant cancers by Roman M. Chabanon, Liudmila Shcherbakova, Magali Lacroix-Triki, Marine Aglave, Jean Zeghondy, Victor Kriaa, Antoine Gougé, Marlène Garrido, Elodie Edmond, Ludovic Bigot, Dragomir B. Krastev, Rachel Brough, Stephen J. Pettitt, Thibault Thomas-Bonafos, Robert Samstein, Christophe Massard, Marc Deloger, Andrew NJ Tutt, Fabrice Barlesi, Yohann Loriot, Suzette Delaloge, Marcel Tawk, Cindy Degerny, Yea-Lih Lin, Barbara Pistilli, Philippe Pasero, Christopher J. Lord, Sophie Postel-Vinay

“…Abstract ADAR1 is an RNA editing enzyme which prevents autoimmunity by blocking interferon responses triggered by cytosolic RNA sensors, and is a potential target in immuno-oncology. However, predictive biomarkers for ADAR1 inhibition are lacking. …”
Get full text

Long-Term Settlement of High Concrete-Face Rockfill Dam by Field Monitoring and Numerical Simulation by Xinjie Zhou, Xinjian Sun, Junxing Zheng, Haoyuan Jiang, Yongye Li, Zhigang Li, Zhongxiang Ma, Peng Cao, Qibing Zhan, Yawei Zhao

“…The calibrated FEM model is used to predict stress and deformation behavior of the Xujixia high CFRD after three years of operation period. …”
Get full text

Hemodynamic assessment of rupture risk during growth stages in middle cerebral artery aneurysms treated with coiling by Rifaqat Ali, Hana Ihsan Hassan, Aman Sharma, Aashim Dhawan, P. Sharma, Waam Mohammed Taher, Mariem Alwan, Ali Fawzi Al-Hussainy, Mahmood Jasem Jawad, Hiba Mushtaq

“…In contrast, coiling consistently suppressed these metrics across all volumes: peak WSS fell below 100 Pa, average WSS remained under 5 Pa, and OSI was reduced to below 0.03. AWSS and OSI reductions indicated dampened flow oscillations and reduced biomechanical stress. …”
Get full text

Loudness Assessment of Musical Tones Equalized in A-weighted Level by Despina KLONARI, Konstantinos PASTIADIS, Georgios PAPADELIS, George PAPANIKOLAOU

“…Consequently, the use of elaborate computational prediction is stressed, in view of the necessity for thorough investigation of factors affecting the perception of loudness of musical sounds.…”
Get full text

Modelos de materiales hiperelásticos para el análisis de los elastómeros usando el MEF // Hyperelastic material models for the analysis of elastomers by using FEM. by R. A. González Carbonell, E. Álvarez García, J. L. Moya Rodríguez, K. Abreu González

“…</p><p>____________________________________________________________________________</p><p>Abstract<br />This researching deals with the material models used by Finite Elements software to predict the<br />behavior of the stress and strain of hyperelastic materials. …”
Get full text

60 Investigating sociodemographic influence on trauma exposure and neural alterations in young adults by Abigail Bossa, Claire Marino, Caitlin Sharp, Tanya Garg, Shreya Bavdekar, Mary Halvorsen, Benjamin Suzrez-Jimenez

“…Results/Anticipated Results: It is anticipated that sociodemographic factors such, race and ethnicity, and highest level of school completed may influence the likelihood of experiencing traumatic events. It is predicted that in the resting-state MRI analysis that there will be altered functional connectivity in trauma exposed young adults in regions such as the amygdala, hippocampus, and prefrontal cortex since those regions are implicated in emotional regulation and stress response. …”
Get full text

Modelling and Production of Injection Moulded Polyvinylchloride--Sawdust Composite by C.O. Aliyegbenoma, J.A. Apkobi, D.D. Olodu

“…The values obtained from the validation of these models were therefore found to be satisfactory, and shows good predictability of the model and its adequacy. Keywords: Composite, Modeling, Polyvinylchloride, Sawdust. …”
Get full text

Mechanical Effects of Lining Thinning in Shallow Four-Track High-Speed Railway Tunnels: Field Monitoring and Numerical Analysis by Shaohui He, Bo Jiang, Jianfei Ma

“…The actual rock pressure in the XBS Tunnel was significantly lower than theoretical predictions, and the tunnel primarily experienced genuine pressure rather than loosening pressure during construction, with the secondary lining serving as a safety reserve. …”
Get full text

Research on the influence of epoxy resin on the service life of bond wire in power devices by HUA Wenbo, DENG Erping, LIU Peng, NIU Hao, YANG Shaohua, DING Lijian

“…Then, for the 1 200 V, 25 A TO devices used in the experiment, a coupled finite element model of electrical-thermal-stress multiphysics was established using COMSOL simulation software to explore the different thermal expansion coefficients before and after the glass transition temperature (<italic>T</italic>_g) of epoxy resin and the influence of different thickness parameters of epoxy resin on the stress strain of bonding wire, and the service life of bonding wire was predicted by combining the fatigue model. …”
Get full text

An Exploratory Study Into the Effects of Regular Cold‐Water Sea Swimming on Daily Indices of Mental Health by Jill Forsten, Mark A. Wetherell

Get full text

Antibacterial Evaluation of Tricyclic Antidepressants Against <i>S. aureus</i> and the Possible Pathways of the Mechanism of Action by Vitória Pessoa de Farias Cabral, Daniel Sampaio Rodrigues, Lívia Gurgel do Amaral Valente Sá, Lara Elloyse Almeida Moreira, Cecília Rocha da Silva, João Batista de Andrade Neto, Érica Rayanne Mota da Costa, Thais Lima Ferreira, Leilson Carvalho de Oliveira, Beatriz Oliveira de Souza, Dávylla Rênnia Saldanha Pinheiro, Bruno Coêlho Cavalcanti, Islay Lima Magalhães, Manoel Odorico de Moraes, Hélio Vitoriano Nobre Júnior

“…The mechanism of TCAs, isolated and combined with OXA, was associated with a reduction in cell viability, resulting from their action on the bacterial genetic material and generation of oxidative stress. …”
Get full text

Overexpression of the STOX1B isoform of STOX1 triggers preeclampsia-like symptoms through HNF4α-dependent alterations of coagulation cascades in mice by Hélène Collinot, Louise Strubé, Ikram Benouda, Johan Castille, Sandrine Floriot, Nathalie Daniel-Carlier, Bruno Passet, Franck Lager, Isabelle Lagoutte, Gilles Renault, Benjamin Saintpierre, Maryline Favier, Djihane Djeridane, Céline Méhats, Francisco Miralles, Jean-Luc Vilotte, Daniel Vaiman

“…The two isoforms have opposite function on major genes involved in trophoblast syncytialization and oxidative stress management. Placenta-fetal overexpression of STOX1A induces preeclampsia in mice. …”
Get full text

Sphingosine 1-Phosphate Receptor 1 Is Required for MMP-2 Function in Bone Marrow Mesenchymal Stromal Cells: Implications for Cytoskeleton Assembly and Proliferation by Chiara Sassoli, Federica Pierucci, Alessia Tani, Alessia Frati, Flaminia Chellini, Francesca Matteini, Ambra Vestri, Giulia Anderloni, Daniele Nosi, Sandra Zecchi-Orlandini, Elisabetta Meacci

“…Notably, active S1PR1/MMP-2 signalling is required for F-actin structure assembly (lamellipodia, microspikes, and stress fibers) and, in turn, cell proliferation. Moreover, in experimental conditions resembling the damaged/regenerating tissue microenvironment (hypoxia), S1P/S1PR1 system is also required for HIF-1α expression and vinculin reduction. …”
Get full text