Fungus-targeted nanomicelles enable microRNA delivery for suppression of virulence in Aspergillus fumigatus as a novel antifungal approach by Tatsuya Inukai, Rikuto Watanabe, Yoshiki Murakami, Horacio Cabral, Masahiko Kuroda, Shigeki Nakamura

“…The protein amount of Alb1-HAp was reduced by one-third after the introduction of the miRNA. Moreover, the reduction in melanin after miRNA transfection promoted the killing of fungus by hydrogen peroxide-induced oxidative stress and sensitised the fungus to neutrophil attack. …”
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Effect of corrosion and sandblasting on the high cycle fatigue behavior of reinforcing B500C steel bars by Marina C. Vasco, P. Polydoropoulou, Apostolos N. Chamos, Spiros G. Pantelakis

“…Fatigue tests were performed at a stress ratio, R, of 0.1 and loading frequency of 20 Hz. …”
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A Discrete‐Element‐Based Pore‐Scale Hydromechanical Approach to Investigate the Hysteresis Effect on the Unsaturated At‐Rest Earth Pressure Coefficient by Hossein Ansari, Ghassem Habibagahi, Ehsan Nikooee

“…The results indicate that the earth pressure coefficient is highly dependent on the hydraulic path as well as the drying–wetting cycles, where a considerable reduction in the degree of hysteresis in K0 was observed during the second cycle of drying–wetting and this reduction is more prominent in the samples of lower density.…”
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Cardioprotective effect of perakine against myocardial ischemia-reperfusion injury of type-2 diabetic rat in Langendorff-perfused rat hearts: the role of TLR4/NF-κB signaling pathw... by Jinli Wang, Li Fan

“…The level of oxidative stress (MDA, SOD, and GSH) was also found to be lowered in IR rats, together with a reduction in the production of pro-inflammatory cytokines (IL-1b, IL-6, IL-17, and TNF-a). …”
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Multi-objective optimization of an origami inspired super-expandable scaffold for distraction osteogenesis by MA Bagheri, CE Aubin, ML Nault, I Villemure

“…A Bayesian machine learning platform was used to predict key structural and mechanical properties influencing bone regeneration, followed by multi-objective optimization. …”
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Function and firing of the Streptomyces coelicolor contractile injection system requires the membrane protein CisA by Bastien Casu, Joseph W Sallmen, Peter E Haas, Govind Chandra, Pavel Afanasyev, Jingwei Xu, Martin Pilhofer, Susan Schlimpert

“…CIS from Streptomyces coelicolor (CISSc) are localized in the cytoplasm. Under stress, they induce cell death and impact the Streptomyces life cycle. …”
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Mechanical Characteristics of Green Composites of Short Kenaf Bast Fiber Reinforced in Cardanol by Zahra Dashtizadeh, Abdan Khalina, Francisco Cardona, Ching Hao Lee

“…On the contrary, short kenaf fiber insertion creates a stress concentration spot at the fiber’s end causing slightly lower flexural properties. …”
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CDR clipping-induced heterodimerization: identification of a novel dimerization mechanism in a co-formulated antibody cocktail via a multifaceted mass spectrometry approach by Andrew J Heindel, Yang Shen, Timothy N Tiambeng, Yuetian Yan, Shunhai Wang, Ning Li

“…Additionally, by probing the disulfide bond susceptibility changes via limited reduction and middle-down analysis, the structural changes of the involved domains were studied. …”
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Experimental Study of Influence of Support Failures on Rockbursts under True-Triaxial Condition by Guoshao Su, Tianbin Li, Jianqing Jiang, Guoqing Chen, Jinghai Mo

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Thick-Anchored Dual-Layer Locking Supporting Technique in Gob-Side Entry Driving with the Narrow Pillar: A Case Study by Changliang Han, Yuxin Yuan, Nong Zhang, Yi Zhao, Qisheng Zhang, Kai Song, Min Wei, Yuxin Guo

“…The results of numerical simulation and field industrial tests show that the TADL support technique can effectively control the deformation of surrounding rock and drive away tensile stress. Compared with the original support scheme, the roof displacement of the roadway is significantly reduced by more than 16% after TADL support. …”
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Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis by Amit U Joshi, Nay L Saw, Hannes Vogel, Anna D Cunnigham, Mehrdad Shamloo, Daria Mochly‐Rosen

“…Abstract Bioenergetic failure and oxidative stress are common pathological hallmarks of amyotrophic lateral sclerosis (ALS), but whether these could be targeted effectively for novel therapeutic intervention needs to be determined. …”
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Prevalence and Associated Factors of Access to Improve Sanitation Facilities Among Households in Ethiopia: Evidence From the 2016 Ethiopian Demographic and Health survey by Amare Wubishet Ayele

“…The prevalence of access to improved sanitation facilities is still low in Ethiopia; priority should be given to households who are rural residents, less-educated, and low-income groups. The study stresses the need for government and NGOs to adopt a multifaceted approach, including infrastructure development, income generation, hygiene education, and community engagement to enhance sanitation.…”
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How to promote the use of the target language in the classroom

“…Conclusion The issue stresses the need for pedagogical cohesion in a multilingual society. …”
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Repurposing Rafoxanide: From Parasite Killer to Cancer Fighter by Teresa Pacifico, Lorenzo Tomassini, Livia Biancone, Giovanni Monteleone, Carmine Stolfi, Federica Laudisi

“…Rafoxanide exerts its anticancer activity through multiple complementary mechanisms, including the induction of endoplasmic reticulum stress, cell cycle arrest, apoptosis, and immunogenic cell death. …”
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Nutrient Availability Alters the Effect of Autophagy on Sulindac Sulfide-Induced Colon Cancer Cell Apoptosis by Shiun-Kwei Chiou, Neil Hoa, Lisheng Ge, Martin R. Jadus

“…Induction of autophagy under various cellular stress stimuli can lead to either cell survival or cell death via apoptotic and/or autophagic (nonapoptotic) pathways. …”
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Comparative study: trimetazidine versus olanzapine on cognitive dysfunction and behavioral changes in ketamine-induced psychosis model in mice by Yosra Magdy, Sherif Kamar, Hoda Fansa, Sara Khedr, Amina Sedky

“…Abstract Background Mitochondrial dysfunction and oxidative stress may contribute to schizophrenia. Negative symptoms and cognitive dysfunction in individuals with schizophrenia are resistant to anti-psychotic medications, but physical exercise is an effective treatment. …”
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Frictional Experiments on Granitic Faults: New Insights into Continental Earthquakes and Micromechanical Mechanisms by Huiru Lei, Shimin Liu, Wenhao Dai

“…The velocity-weakening regime shifts to higher temperatures with increasing slip velocity or decreasing pore fluid pressure. Temperature, normal stress, pore fluid pressure, and slip velocity interact to modulate frictional stability. …”
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Age-Related Alterations in the Expression of Genes and Synaptic Plasticity Associated with Nitric Oxide Signaling in the Mouse Dorsal Striatum by Aisa N. Chepkova, Susanne Schönfeld, Olga A. Sergeeva

“…Corticostriatal NO-dependent LTD induced by pharmacological activation of group I metabotropic glutamate receptors underwent significant reduction with aging and could be restored by inhibition of cGMP hydrolysis indicating that its age-related deficit is caused by an altered NO-cGMP signaling cascade. …”
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Physical modeling of glacier contact with bedrock (experiment) by V. P. Epifanov, A. F. Glazovsky, N. I. Osokin

“…Influence of shear to normal stresses ratio on the adhesive ice/substrate strength has been shown. …”
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Effects of Integrating Music Therapy into Family Support System on Adolescent Depression by Jie Zhou, Liying Liu, Lipeng Zheng

“…The ASLEC score showed a greater reduction in aspects such as interpersonal relationships, academic stress, punishment, and loss (P < 0.05). …”
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