Integrated transcriptomics and metabolomics analysis reveal the regulatory mechanisms underlying the combined effects of heat and glucose starvation on carotenoid biosynthesis in R... by Xingyu Huang, Caina Guo, Xiaolan Huang, Meixia He, Jingdie Fan, Yuan Chen, Jingwen Qiu, Qi Zhang

“…The results of multiomics analysis revealed that the effects of heat stress and glucose starvation on promoting carotenoid biosynthesis appeared to be additive, with the combined stress leading to a further increase in reactive oxygen species (ROS) levels and a reduction in enzymatic antioxidant capacity, while carotenoid biosynthesis was prioritized simultaneously. …”
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Engineered Prx-LCA2 fusion protein restores oxidative skin damage via enhanced intracellular peroxidase delivery by Di Liu, Yafen Zhan, Jiaqi Qu, Hongping Qiao, Na Li, Yeli Zhang, Xiaoying Wu

“…In vitro, H2O2-induced oxidative stress in A431 cells was alleviated by Prx-LCA2 treatment, as evidenced by increased cell viability, reduced ROS levels, enhanced antioxidant enzyme activities, and decreased levels of MDA and PCG. …”
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Study on the Dilatancy Behavior of Coral Sand and Its Influence on Shear Strength Parameters by Yuanqi Shi, Zhenzhong Cao, Liping Jing, Xiangyu Zhu

“…A dilatancy equation for coral sand was proposed, incorporating the dilatancy index, relative density, and mean effective stress. The results indicate the following: (1) Within the confining pressure range of 25–400 kPa, the stress–strain curves exhibit varying degrees of strain softening. …”
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Development of Powerly, unguided mobile app intervention preventing postpartum depression and anxiety & study protocol of randomized clinical trial by Marta A. Marciniak, Judith Rohde, Kenneth S.L. Yuen, Harald Binder, Henrik Walter, Matthias J. Wieser, Raffael Kalisch, Karin Roelofs, Birgit Kleim

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The relationship between the indicators of spectral analysis of heart rate variability and sociopsychological adaptation to work load in people with disabilities by E. A. Nagovitsyna, N. N. Vasilyeva

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The RAE1-STOP1 module regulates ABA sensitivity in early seedlings of Arabidopsis by Yuqing Zhang, Min Huang, Yinyin Liu, Mengmeng Yang, Yuqi Hou, Chao-Feng Huang, Ning Ning Wang, Lei Li

“…This may suggest a bidirectional role of STOP1 in ABA sensitivity and highlights the critical importance of maintaining STOP1 homeostasis to balance growth and stress tolerance.…”
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Psychological conditions for the development of the communicative culture of students by Elena V. Goverdovskaya, Anna M. Dokhoyan, Ekaterina A. Tatarintseva

“…The importance of introducing active teaching methods in the learning process is stressed. The goal of the study is to describe and analyze the experience in the development of students’ communicative culture relevant for the system of higher pedagogical education. …”
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The pivotal regulatory role of the FEV-SLC7A11 axis in ferroptosis elucidates the anti-aging mechanism of β-sitosterol in a cross-species study by Zhihan Fang, Zhihan Fang, Liyao Xie, Jing Wang, Junyi Li, Yirui Pan, Lei Chen, Shuyi Cao, Qi Zhou, Shaobin Li, Chao Zhang, Li Li

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Coordination of abscisic acid and hydraulic signals in stomatal closure and yield of soybean genotypes with varying isohydry under different water conditions by Sanwei Yang, Haixia Zhang, Yi Jin, Neil C. Turner, Jiayin Pang, Yinglong Chen, Jin He

“…However, under severe drought stress, isohydric genotypes suffered less yield reduction (70 % and 72 % for isohydric cultivars vs. 79 % and 77 % for two anisohydric landraces) and increased more WUEg compared to anisohydric genotypes. …”
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Melatonin Enhances Tomato Salt Tolerance by Improving Water Use Efficiency, Photosynthesis, and Redox Homeostasis by Chen Ru, Yuxuan Liu, Xingjiao Yu, Chuanliu Xie, Xiaotao Hu

“…The results showed that salt stress significantly reduced the leaf relative water content and root hydraulic conductivity, suppressed the photosynthetic rate, and ultimately caused significant reductions in the aboveground and root biomass. …”
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Enhancing care service utilization and reducing burden: the role of needs assessments for dementia caregivers in long-term care by Yung-Yu Su, Wen-Fu Wang, Kai-Ming Jhang, Lih-Wen Mau, Chun-Min Chen

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Investigation of the dynamics of lipid peroxidation products in the blood and liver of rats of different ages with experimentally induced dyslipoproteinemia on the background of me... by O. N. Pavlova, O. N. Tulaeva, O. N. Gulenko, D. S. Gromova, V. V. Leonov, E. V. Lukenyuk

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Hybrid molecule SA-10 and its PLGA nanosuspension protect human and rodent retinal ganglion cells against neuronal injury by Jennifer H. Pham, Wei Zhang, Kim-Tuyen T. Le, Bindu Kodati, Charles E. Amankwa, Biddut DebNath, Gretchen A. Johnson, Thien T. Bui, Rachel Y. Gitter, Jonah P. Gutierrez, Brendon R. Hatfield, Rojan Satyal, Ella R. Sinnott, Raghu R. Krishnamoorthy, Suchismita Acharya, Dorota L. Stankowska

“…SA-10 upregulated oxidative stress markers (NRF2 and HMOX1) and enhanced RGC survival in NF-deprived HREs. …”
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Peer delivered, emotion regulation-focused mental health prevention training for fire fighter trainees: Design and methodology of a randomized controlled trial by Eric C. Meyer, Todd Farchione, Nathan A. Kimbrel, Oi-Man Kwok, Michelle L. Pennington, Jessica Rostockyj, Suzy B. Gulliver

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Mapping the multidimensional factors of medical student resilience development: A scoping review by Syeda Rubaba Azim, Muhamad Saiful Bahri Yusoff, Nurhanis Syazni Roslan

“…Abstract Resilience plays a vital role in promoting mental wellbeing by facilitating recovery from stressful experiences. Medical students face intense academic and clinical requirements throughout their rigorous training. …”
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A time series analysis of monthly Holstein milk yield and composition in a hot environment by Irene Chavarría, Oscar Ángel-García, Alan S. Alvarado, Viridiana Contreras, Dalia I. Carrillo, Ulises Macías-Cruz, Leonel Avendaño-Reyes, Miguel Mellado

“…The mean predicted fat content was highest in January (3.60 %; CI= 3.48-3.71 %) and lowest in July (3.44%; CI= 3.29-3.59 %). …”
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Optimization of secondary flow path clearance in centrifugal blood pump: a combined numerical and experimental study by Chenying Zhu, Ping Ye, Zhaohua Chang

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Hemodynamic predictors of rupture in abdominal aortic aneurysms: a case series using computational fluid dynamics by Kiyoon Moon, Yosep Lee, Junseong Lee, Youngki Son, Youngje Woo, Eunju Jang, Sangseob Yun, Suncheol Park, Jangyong Kim

“…BackgroundAbdominal aortic aneurysm (AAA) rupture is a life-threatening event traditionally predicted by aneurysm diameter. However, many clinical observations have revealed that rupture can occur even in small aneurysms, suggesting the influence of additional biomechanical factors such as hemodynamics. …”
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The impact of the war in Ukraine on the well-being of German medical students: a mixed-methods study by Marie Stelter, Michaela Zupanic, Angelika Taetz-Harrer, Julia Nitsche, Arndt Büssing, Jan P. Ehlers

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Probiotics as Antioxidant Strategy for Managing Diabetes Mellitus and Its Complications by Max Denisson Maurício Viana, Sthefane Silva Santos, Anna Beatriz Oliveira Cruz, Maria Vitória Abreu Cardoso de Jesus, Pedro Santana Sales Lauria, Marvin Paulo Lins, Cristiane Flora Villarreal

“…Strains from the <i>Lactobacillus</i> and <i>Bifidobacterium</i> genera are the most extensively studied and have demonstrated hypoglycemic and antioxidant effects, including the enhancement of key antioxidant enzymes and reductions in lipid peroxidation and nitrosative stress markers. …”
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