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1121
The Association of OLFM4 with the Progression and Cisplatin Resistance of Head and Neck Squamous Carcinoma
Published 2025-05-01Get full text
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1122
The antioxidant and therapeutic effects of Malva sylvestris extract on testicular tissue and sperm quality in varicocele-induced adult Wistar rats
Published 2025-06-01“…Results Varicocele leads to the induction of apoptosis, the occurrence of DNA damage, a reduction in SIRT1 and FOXO1, and an increase in NRF2, TGF-β, and NF-κB gene expression. …”
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1123
Antioxidant Mechanisms of the Protective Action of Selenase in Experimental Chronic Generalized Periodontitis
Published 2025-03-01“…The CGP model led to the typical clinical signs of periodontitis, including hyperemia, edema, gingival pocket formation, bleeding, tooth mobility, as well as an increase in molecular–biochemical markers of nitrosative stress and a reduction of endogenous antioxidants in the blood. …”
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1124
Optimizing antihypertensive therapy in postmenopausal women with metabolic syndrome
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1125
Cerebellar Purkinje Cells and GABA Neurotransmission in the Diabetic Rodent Models: A Systematic Review
Published 2025-07-01“…Impaired GABAergic neurotransmission might result as parts of oxidative stress and inflammation induced by hyperglycemia in the cerebellar cells. …”
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1126
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1127
Exploring regulatory roles of putrescine-doped zinc oxide nanoentities on ethylene signaling, redox imbalance, and programmed cell death in drought-stressed rice (Oryza sativa L.)...
Published 2025-08-01“…These effects reduced DS-induced oxidative signaling through enhanced antioxidation. Oxidative stress under DS was mitigated, as indicated by a 41% reduction in H2O2 in the DS+PUT-nZnO treatment. …”
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1128
Through its genoprotective, mitochondrial bioenergetic modulation, and antioxidant effects, Fucoxanthin and its metabolite minimize Ochratoxin A-induced nephrotoxicity in HK-2 huma...
Published 2025-07-01“…A significant deregulation of normal cellular pathways including genotoxicity (DNA damage percentage), mitochondrial bioenergetics disruption (PDH, α-KG, MCI and MCIII complexes activities, ATP levels and mitochondrial membrane potential), downregulation of some mitochondrial genes (ND1, ND5, CO-1 and ATP6/8) expression, mitophagy inhibition (PARK1 and parkin), Oxidative stress induction (ROS and TBARS), oxidative stress genes downregulation (HO-1 and Nrf2), antioxidant enzymatic activity reduction (ROS and CAT), and apoptotic mediator markers elevation (Caspases- 3, 8 and 9, and Bax/Bcl-2 ratio) were observed in OTA mono-treated cells compared to untreated control cells. …”
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1129
Men of Color Health Awareness intervention: changes in adrenocortical activity assessed using fingernail cortisol
Published 2025-07-01“…IntroductionA randomized controlled trial (#NCT03745703) assessed the efficacy of a tailored stress reduction intervention (Men of Color Health Awareness; MOCHA) aimed at improving the health of middle-aged African-American men. …”
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1130
Hepatic restorative potential of Portulaca oleracea ethanolic extract and/or metformin in type II diabetes mellitus model induced by high-fat diet and STZ
Published 2025-07-01“…Consequently, this research sought to investigate the possibilities of purslane ethanolic extract in protecting against liver damage, oxidative stress, and the inflammatory response associated with diabetes. …”
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1131
Zinc toxicity induces intestinal cell death via inhibiting NAD+ synthesis in mice and IPEC-J2 cells
Published 2025-01-01“…We next determined the dynamics of oxidative stress and energy metabolism in Zn overload treatment IPEC-J2 cells. …”
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1133
An overview of molecular mechanisms and QTLs associated with arsenic tolerance in rice
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1134
<i>Origanum majorana</i> Extracts: A Preliminary Comparative Study on Phytochemical Profiles and Bioactive Properties of Valuable Fraction and By-Product
Published 2025-07-01“…Both extracts (20 µg/mL) fully restored oxidative balance in hemin-stressed AC16 cardiomyocytes, without altering the expression of catalase, heme-oxygenase 1, superoxide dismutase 2, or ferritin. …”
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1135
YOD1 regulates oxidative damage of dopamine neurons in Parkinson's disease by deubiquitinating PKM2
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A latent profile analysis of self-leadership associated with coping styles among general practice students
Published 2025-05-01“…Abstract General practice students are faced with greater stress and poorer career prospects than other medical students. …”
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1138
Relationships as determinants of substance use amongst street children in a local government area in south-western Nigeria
Published 2008-10-01“…On logistic regression, only low connectedness with mother (OR 2.4,95% C11.194.98) and friend (OR 3.1,95% C11.705.72) predicted current substance use. Conclusion: The study documented the important role of positive relationships between street children and their friends/mothers in preventing psychoactive substance use.…”
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Alterations in GSH/GSSG and CyS/CySS redox status in small cell lung cancer patients undergoing chemotherapy
Published 2025-07-01“…Abstract Background In small cell lung cancer (SCLC), oxidative stress disrupts redox balance and contributes to tumor progression and treatment resistance through DNA damage, inflammation, and tumorigenesis. …”
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1140