Anticancer properties of copolymer nanoparticles loaded with Foeniculum vulgare derivatives in Hs578T and SUM159 cancer cell lines by Shima Bourang, Sodabeh Jahanbakhsh Godehkahriz, Mehran Noruzpour, Rasool Asghari Zakaria, Sergio Granados-Principal

“…Moreover, the drug release pattern illustrated a higher release rate from synthesized nanoparticles under acidic conditions (pH = 5). …”
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Peer perceptions of clinicians using generative AI in medical decision-making by Haiyang Yang, Tinglong Dai, Nestoras Mathioudakis, Amy M. Knight, Yuna Nakayasu, Risa M. Wolf

“…Participants also acknowledged GenAI’s value in improving accuracy (4.30, p < 0.002) and rated institutionally customized GenAI more favorably (4.96, p < 0.001). …”
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Global directions of change in moral norms: a test of the moral argument theory by Pontus Strimling, Kimmo Eriksson, Irina Vartanova, Joel Krueger, Isabela Hazin

“…We test this theory in a preregistered study of the arguments for both sides of 33 moral issues for which the global directions and rates of norm change were estimated in available longitudinal survey data from 94 societies. …”
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Respiratory Support with Limited Tidal Volume and Peak Pressure in Patients with Acute Respiratory Distress Syndrome by A. V. Vlasenko, D. A. Ostapchenko, G. N. Meshcheryakov, P. Yu. Osipov

“…The paper presents the results of a study, which prove the advantages of artificial ventilation with a descending air flow on inspiration, tidal volume 6 ml/kg body weight; P peak &lt; 30 cm H2O in showing its efficiency, by optimizing the parameters of the respiratory pattern, by improving gas exchange in the lung, by reducing the time of respiratory support, the length of stay in an intensive care unit, and mortality rates as compared with artificial square-wave air flow on inspiration, TV 12—15 ml/kg body weight; Ppeak tracheal &gt;35 cm H2°.…”
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Factors Affecting Aggressive Behavior Among Teenage Students: A Statistical Study by Kauser Shaheen, Majid Kaleem, Muhammad Abbas, Asim Iftikhar, Muhammad Ramzan

“…Aggressive behavior in the classroom was linked to low academic engagement ratings, good attitudes toward learning, friends in the classroom, and the perception of teacher support. …”
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Decentralized Immunization Monitoring: Lessons Learnt from a Pilot Implementation in Kumbotso LGA, Kano State, Nigeria by Adam Attahiru, Yahaya Mohammed, Fiyidi Mikailu, Hyelshilni Waziri, Ndadilnasiya Endie Waziri, Mustapha Tukur, Bashir Sunusi, Mohammed Nasir Mahmoud, Nancy Vollmer, William Vargas, Yusuf Yusufari, Gustavo Corrêa, Heidi W. Reynolds, Teemar Fisseha, Talatu Buba Bello, Moreen Kamateeka, Adefisoye Oluwaseun Adewole, Musa Bello, Imam Wada Bello, Sulaiman Etamesor, Joseph J. Valadez, Patrick Nguku

“…To enable a better understanding of contextual factors towards increasing uptake, we piloted a Decentralized Immunization Monitoring (DIM) approach in the Kumbotso local government area (LGA) of Kano state, Nigeria, to identify wards with low vaccination rates and understand why this is happening. The findings were used to improve routine immunization (RI) programs and reduce the number of unvaccinated children and children yet to receive their first dose of diphtheria–pertussis–tetanus (DPT) vaccine, referred to as Zero-Dose children (ZD). …”
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Integrating AI-generated content tools in higher education: a comparative analysis of interdisciplinary learning outcomes by Zhang Yan, Tang Qianjun

“…Findings revealed a 37% increase in interdisciplinary project outcomes (measured by collaborative problem-solving scores, cross-domain knowledge integration ratings, and peer evaluation metrics) when AIGC tools were strategically implemented, with significant variations in effectiveness based on implementation approach. …”
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Korean Translation of the GRADE Series Published in the BMJ, ‘Use of GRADE Grid to Reach Decisions on Clinical Practice Guidelines When Consensus Is Elusive’ (A Secondary Publicati... by Hyun Jin Jung, Eu Chang Hwang, Do Kyung Kim, Ho Won Kang, Ja Yoon Ku, Hong Wook Kim, Jae Hung Jung

“…This article is the last of a series providing guidance for the use of the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system for rating the quality of evidence and grading the strength of recommendations in systematic reviews and clinical practice guidelines. …”
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Incidence, prevalence, and burden of type 2 diabetes in China: Trend and projection from 1990 to 2050 by Haojie Zhang, Qingyi Jia, Peige Song, Yongze Li, Lihua Jiang, Xianghui Fu, Sheyu Li, Jinjiao Li

“…Background:. The epidemiological pattern and disease burden of type 2 diabetes have been shifting in China over the past decades. …”
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SPONTANEOUS SPAWNING OF BRAZILIAN SARDINE IN CAPTIVITY by Caio Cesar Franca MAGNOTTI, Fabio Carneiro STERZELECKI, Filipe Santos CIPRIANO, Fabiola Santiago PEDROTTI, Vanessa Martins ROCHA, Vinicius Ronzani CERQUEIRA

“…This is the first report for the genus Sardinella. Following the pattern found in the natural environment, the number of spawns, as well as fertilization and hatching rates were higher in spring, summer and fall than in winter. …”
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EQ-5D utility, response and drug survival in rheumatoid arthritis patients on biologic monotherapy: A prospective observational study of patients registered in the south Swedish SS... by Tanja Schjødt Jørgensen, Carl Turesson, Meliha Kapetanovic, Martin Englund, Aleksandra Turkiewicz, Robin Christensen, Henning Bliddal, Pierre Geborek, Lars Erik Kristensen

“…Overall, DAS28 defined remission and low disease activity were achieved in 20% and 43% of patients, respectively. Drug survival rates were statistically significantly different between bDMARDs (p = 0.01), with the highest rates observed for rituximab, followed by etanercept. …”
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Clinical Features of Liver Injury Induced by Immune Checkpoint Inhibitors in Japanese Patients by Koji Imoto, Motoyuki Kohjima, Tomonobu Hioki, Tomoyuki Kurashige, Miho Kurokawa, Shigeki Tashiro, Hideo Suzuki, Akifumi Kuwano, Masatake Tanaka, Seiji Okada, Masaki Kato, Yoshihiro Ogawa

“…Immune checkpoint inhibitors (ICIs) have improved the survival rate of patients carrying various malignant neoplasms. …”
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The Role of Intestinal Translocation in the Pathogenesis of Pneumonia in Acute Poisoning and the Contribution of Intestinal Lavage to Its Prevention and Resolution by V. A. Matkevich, T. T. Tkeshelashvili, A. G. Vorobyova, N. E. Stolbova, M. M. Potskhveriya, Yu. S. Goldfarb

“…Mortality among the patients with PPD poisoning decreased by 7 times, and with M and CS poisoning, as well as with AlD, there were no deaths, while in the respective comparison groups, the mortality rate for pneumonia was 5.1, 7.4, and 17.4 %, respectively. …”
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Melatonin regulated through GhTDC5 enhances tryptophan decarboxylase against drought stress in cotton by Xin Yu, Xiugui Chen, Ning Wang, Maohua Dai, Zhining Yang, Yapeng Fan, Yuping Sun, Xinrui Zhang, Ruize Song, Menghao Zhang, Hao Lan, Fange Wu, Hui Huang, Xiao Chen, Lidong Wang, Xuke Lu, Shuai Wang, Lixue Guo, Junjuan Wang, Lanjie Zhao, Keyun Feng, Jing Jiang, Wuwei Ye

“…Abstract Tryptophan decarboxylase (TDC) is the rate-limiting enzyme in the biosynthesis of melatonin and plays a crucial role in melatonin production in plants. …”
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Near-Unity Nitrate to Ammonia conversion via reactant enrichment at the solid-liquid interface by Wanru Liao, Jun Wang, Yao Tan, Xin Zi, Changxu Liu, Qiyou Wang, Li Zhu, Cheng-Wei Kao, Ting-Shan Chan, Hongmei Li, Yali Zhang, Kang Liu, Chao Cai, Junwei Fu, Beidou Xi, Emiliano Cortés, Liyuan Chai, Min Liu

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Language-Based Engineering Considering the Trade-off among Words in Design Reflecting User’s Emotion by Nobuhisa KATSUMATA, Sonosuke HARADA, So FUKUHARA, Masao ARAKAWA, Shogo NAKAO, Masahiko FUJIWARA

“…We analyzed the relationship between user ratings and design elements using Quantification Theory Type I and created a database of these relationships. …”
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Features of the functioning of regional airports in the context of the development of the Russian air transportation market by I. N. Rykova, A. A. Alaev, R. S. Gubanov

“…The applied methods of monographic and economic-statistical analysis, rating assessment provided the identification of patterns of changes in the results of airport operations. …”
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Association of cancer and outcomes of patients hospitalized for COVID-19 between 2020 and 2023 [version 2; peer review: 1 approved, 2 approved with reservations, 1 not approved] by Robert F Terry, Rugiatu Z Kamara, Robert J Samuels, Donald S Grant, Sulaiman Lakoh, Mustapha Kabba, Innocent Nuwagira, Yusuf Sheku Tejan, Sia Morenike Tengbe, Ibrahim Franklyn Kamara, Shermarke Hassan, Abdulai Tejan Jalloh, Divya Nair, Laura Merson

“…Conclusions This study's findings underscore the heightened vulnerability of hospitalized COVID-19 patients with cancer, revealing a higher mortality rate, longer hospital stays, and an unstructured pattern of care that reflects the complexity of managing severely ill patients during a public health crisis like the COVID-19 pandemic.…”
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