A clinico-epidemiological study, assessing possible predictors of mortality and health-related quality of life for people living with visceral leishmaniasis – human immune virus (V... by Niyamat Ali Siddiqui, Dhruv Kumar Pandey, Ashish Kumar Singh, Sanjay Kumar Sinha, Mohd. Zahid Ansari, Rishikesh Kumar, Biplab Pal, Vidya Nand Rabi Das, Rajatashuvra Adhikary, Saurabh Jain, Krishna Pandey

“…These patients have a poor VL therapeutic success rate, more drug-related toxicity, and relapses resulting in high mortality. …”
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Clinical characteristics and outcomes of COVID-19 in kidney transplant recipients by R. O. Kantariya, Ya. G. Moysyuk, E. I. Prokopenko, A. R. Karapityan, A. A. Ammosov, A. V. Makevnina, A. A. Gaydarova

“…The comparison study of the clinical pattern, laboratory and instrumental test results, treatment features and outcomes was made.Results. …”
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Clinical profiles of SS-ILD compared with SS-NILD in a Chinese population: a retrospective analysis of 735 patients by Ting Guo, Yaomei Long, Qinxue Shen, Wei Guo, Wang Duan, Xiaoli Ouyang, Hong Peng

“…NSIP (56.3%) was the most frequent HRCT pattern. Compared with pSS patients with ILD (pSS-ILD) patients, sSS patients with ILD (sSS-ILD) patients had a higher incidence of proteinuria (p < .001) and hypercreatinaemia (p = .013), a higher level of erythrocyte sedimentation rate (ESR) (p = .003), low levels of complement 3 (C3) (p = .013), lymphocytes (p = .009) and leukocytes (p = .024), and worse DLCO (%Pred) (p = .035).Conclusions ILD is a common pulmonary involvement in both pSS patients and sSS patients. …”
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Supported Telemonitoring and Glycemic Control in People with Type 2 Diabetes: The Telescot Diabetes Pragmatic Multicenter Randomized Controlled Trial. by Sarah H Wild, Janet Hanley, Stephanie C Lewis, John A McKnight, Lucy B McCloughan, Paul L Padfield, Richard A Parker, Mary Paterson, Hilary Pinnock, Aziz Sheikh, Brian McKinstry

“…No significant differences were identified between groups in weight, treatment pattern, adherence to medication, or quality of life in secondary analyses. …”
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Immunological efficacy and tolerability of vaccination in patients with noncommunicable diseases by O. M. Drapkina, M. N. Mamedov, V. A. Kutsenko, L. N. Ryzhakova, A. V. Emelyanov, B. U. Mardanov, A. V. Kontsevaya

“…The following clinical and paraclinical investigations were carried out: saturation assessment, measurement of temperature, blood pressure and heart rate at rest, pharynx examination, auscultation of the heart and respiratory organs. …”
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The Role of Intestinal Translocation in the Pathogenesis of Pneumonia in Acute Poisoning and the Contribution of Intestinal Lavage to Its Prevention and Resolution by V. A. Matkevich, T. T. Tkeshelashvili, A. G. Vorobyova, N. E. Stolbova, M. M. Potskhveriya, Yu. S. Goldfarb

“…Mortality among the patients with PPD poisoning decreased by 7 times, and with M and CS poisoning, as well as with AlD, there were no deaths, while in the respective comparison groups, the mortality rate for pneumonia was 5.1, 7.4, and 17.4 %, respectively. …”
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An impact of neutrophil extracellular traps to the prothrombotic state and tumor progression in gynecological cancer patients by E. V. Slukhanchuk, V. O. Bitsadze, A. G. Solopova, J. Kh. Khizroeva, N. D. Degtyareva, D. V. Shcherbakov, J.-C. Gris, I. Elalamy, A. D. Makatsariya

“…One of the leading causes in the mortality pattern of cancer patients is accounted for by thrombotic complications. …”
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A COMPREHENSIVE APPROACH TO THE TREATMENT OF PATIENTS WITH ALVEOLAR RIDGE ATROPHY IN PARODONTAL DISEASES: FROM THE USE OF BONE AUGMENTATION TO THE RESTORATION OF FUNCTIONAL OCCLUS... by Yu.O. Kinash, L.V. Kinash, K.V. Honcharov

“… The rate of atrophy is significantly lower with the included dentition defects than with the final ones, as the teeth that limit the newly formed defect are natural constraints for bone resorption. …”
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Near-Unity Nitrate to Ammonia conversion via reactant enrichment at the solid-liquid interface by Wanru Liao, Jun Wang, Yao Tan, Xin Zi, Changxu Liu, Qiyou Wang, Li Zhu, Cheng-Wei Kao, Ting-Shan Chan, Hongmei Li, Yali Zhang, Kang Liu, Chao Cai, Junwei Fu, Beidou Xi, Emiliano Cortés, Liyuan Chai, Min Liu

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Eradication of Helicobacter pylori for prevention of aspirin-associated peptic ulcer bleeding in adults over 65 years: the HEAT RCT by CJ Hawkey, Anthony J Avery, Carol AC Coupland, Colin J Crooks, Jennifer S Dumbleton, FD Richard Hobbs, Denise Kendrick, Michael Moore, Clive Morris, Gregory Rubin, Murray Smith, Diane Stevenson

“…Limitations and future work Studying subjects already established on aspirin probably contributed to the low event rate. A future study should investigate subjects starting on aspirin when the event rate is higher. …”
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Performance Assessment of the Concepta Automated ANA Detection System in Routine Clinical Samples by Kübra Evren, Ayşe Nur Ceylan, Mehmet Akif Durmuş

“…The sensitivity and specificity were found to be 99.08% and 97.61%, respectively, with positive and negative predictive values of 87.96% and 99.83%. High concordance rates were observed for homogeneous (95.7%), centromere (92.3%), and nucleolar (92.1%) patterns, while lower rates were noted for speckled (60%) and cytoplasmic (44.4%) patterns.Conclusion: The Concepta automated system demonstrated very high accuracy in ANA positive and negative discrimination, comparable to other automated systems. …”
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GPCR kinases phosphorylate GPCR C-terminal peptides in a hierarchical manner by Arnelle Löbbert, Nils Lorz, Edda S. F. Matthees, Philip Rößler, Carsten Hoffmann, Alvar D. Gossert

“…Our data reveal that the kinases are promiscuous with respect to the substrate peptide, but produce clearly defined phosphorylation patterns on each substrate. We found pronounced differences in the rates at which certain residues are phosphorylated, in particular in the PXPP motifs in rhodopsin and β1AR. …”
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Breastfeeding Supports and Services in Rural Hawaii: Perspectives of Community Healthcare Workers by Jeanie L. Flood

“…In the state of Hawaii, breastfeeding initiation rates are higher than the national average but fall below target rates for duration. …”
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A computational DNA methylation method to remove contaminated DNA from spent embryo culture medium for noninvasive preimplantation genetic testingResearch in context by Yidong Chen, Jin Huang, Fuchou Tang, Lu Wen, Jie Qiao

“…By testing simulated SECM samples, the method demonstrated a substantial reduction in the false-negative rate even with up to 75% cumulus cell contamination. …”
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Analysis of the molecular nature associated with microsatellite status in colon cancer identifies clinical implications for immunotherapy by Wei Wu, Qihan Fu, Lulu Liu, Yi Zheng, Hangyu Zhang, Peng Zhao, Weijia Fang, Xuanwen Bao, Shaobing Cheng, Xiaomeng Dai, Xudong Zhu, Zhou Tong, Fanglong Liu

“…A receiver operating characteristic curve was used to evaluate the accuracy rate of neural network, reaching 100%.Conclusion Our analysis unraveled the difference in the molecular nature and genomic variance in MSI and MSS colon cancer. …”
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Examining the Spatial Disequilibrium and Driving Factors of Population Aging and Elderly Service Resource Allocation in Rural Areas: A Case Study of Wenzhou City by Xiang Xiaoye, Lin Liyue, Xu Shiyu, Huang Tao

“…The results can be summarized as follows: 1) As Wenzhou enters a deeply aging society, the spatial distribution of the elderly population, elderly population density, population aging coefficient, elderly population support ratio, and comprehensive aging index are basically the same, showing a gradually increasing spatial pattern from the municipal district to the peripheral streets of the municipal district to the remote towns; 2) Elderly care service resources in Wenzhou present an asymmetrical and unbalanced north-south spatial distribution pattern with the municipal districts as " diversified supply in municipal streets, basic guarantee in developed coastal towns, and shortage of supply in inland mountainous towns "; 3) The streets of the municipal district have rich elderly care service resources, including Grade 3 general hospitals and comprehensive nursing homes, to provide diversified elderly care services for the elderly in the municipal district; there are many old-age care facilities such as hospitals, clinics, and nursing homes in Ruian, Yueqing City, and central towns such as Hongqiao and Aojiang, which provide basic old-age security for the elderly in and around the area. …”
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Functional Connectivity Biomarker Extraction for Schizophrenia Based on Energy Landscape Machine Learning Techniques by Janerra D. Allen, Sravani Varanasi, Fei Han, L. Elliot Hong, Fow-Sen Choa

“…Schizophrenia is associated with impaired functional connectivity but characterizing the complex abnormality patterns has been challenging. In this work, we used resting-state functional magnetic resonance imaging (fMRI) data to measure functional connectivity between 55 schizophrenia patients and 63 healthy controls across 246 regions of interest (ROIs) and extracted the disease-related connectivity patterns using energy landscape (EL) analysis. …”
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Overweight and Helicobacter pylori infection: a correlation in metabolic dysfunction-associated fatty liver disease by Xu Chen, Jiayue Fu, Jiayue Fu, Kejia Jin, Kejia Jin, Zixuan Yang, Zixuan Yang, Yidan Qian, Yidan Qian, Kehan Mei, Yihan Wang, Jialei Min, Yilin Du, Zaisheng Zhu, Zaisheng Zhu, Shengcun Li, Shengcun Li

“…Therefore, eradication of H. pylori infection may have positive implications for reducing the incidence rate of overweight MAFLD.…”
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Epidemiology and genetic characterization of porcine reproductive and respiratory syndrome virus in Fujian Province, China, from 2023 to 2024 by Long-Bin Kang, Long-Bin Kang, Qiu-Yong Chen, Qiu-Yong Chen, Bing He, Bing He, Ren-Jie Wu, Ren-Jie Wu, Jing-Li Qiu, Jing-Li Qiu, Ru-Jing Chen, Ru-Jing Chen, Xue-Min Wu, Xue-Min Wu, Long-Bai Wang, Long-Bai Wang, Lun-Jiang Zhou, Lun-Jiang Zhou

“…The results revealed that the overall prevalence rate of PRRSV was 16.79% (44/262), PRRSV-1 and PRRSV-2 genotypes were co-prevalent in Fujian. …”
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CONCOMITANT CARDIOVASCULAR DISEASES AND ANTIHYPERTENSIVE TREATMENT IN OUTPATIENT PRACTICE (BY THE RECVASA REGISTRY DATA) by M. M. Loukianov, S. A. Boytsov, S. S. Yakushin, S. Yu. Martsevich, A. N. Vorobyev, A. V. Zagrebelnyy, N. N. Nikulina, K. G. Pereverzeva, E. A. Pravkina, A. D. Deev, E. V. Kudryashov, E. N. Belova

“…The mean number of prescribed AHDs was 1.73. The mean incidence rate of target blood pressure achievement was 26.1%. …”
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