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2841
Epidemiological characterization of chronic myeloid leukaemia patients at an oncologic centre: A retrospective observational study
Published 2025-07-01“…Background: The chronic myeloid leukaemia population, treatment patterns and responses in Portugal are unknown. The aim of this study is to describe these features in a Portuguese reference centre. …”
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2842
Multi-omics analysis of Taiwanofungus gaoligongensis: effects of different cultivation methods on secondary metabolites
Published 2025-08-01“…This study compared the metabolite profiles and gene expression patterns of the fruiting bodies of T. gaoligongensis with those of three types of cultivated mycelia. …”
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2843
Outcomes of different steroid dosing regimens in critical Covid-19 pneumonia at a Kenyan hospital: A retrospective cohort study.
Published 2024-01-01“…Our study aimed to determine the pattern of steroid dosing and outcomes in terms of critical care mortality, occurrence of dysglycaemias, and occurrence of superadded infections in patients with critical COVID-19.…”
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2844
Impact of Dietary Glutamate on Growth Performance and Flesh Quality of Largemouth Bass
Published 2025-03-01“…The FBW, percent weight gain (PWG), specific growth rate (SGR), feed efficiency (FE), and protein efficiency ratio (PER) initially increased and then decreased with elevating dietary Glu levels. …”
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2845
Fine-scale variability in iceberg velocity fields and implications for an ice-associated pinniped
Published 2025-06-01“…Iceberg velocities typically followed a similar diurnal pattern: flow was weak and variable in the morning and strong and unidirectional in the afternoon. …”
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2846
Kinetics of silicon extraction into alloy from a mixture of amorphous rocks
Published 2025-06-01“…It was established that when the melting the amorphous rocks, with an increase in the degree of silicon extraction into the alloy, the apparent activation energy decreases, that is a manifestation of diffusion processes, obviously associated with the formation of a silicon carbide layer on the coke surface. The rate of silicon extraction into the alloy when the melting the amorphous rocks is higher than when the melting quartzite. …”
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2847
Early Dynamics of Circulating Tumor DNA Following Curative Hypofractionated Radiotherapy Related to Disease Control in Lung Cancer
Published 2025-05-01“…The Dmax showed better disease control rate with marginal significance (<i>p</i> = 0.081). …”
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2848
Breaking barriers: targeted delivery of resveratrol in lung cancer using folate-integrated and pH-responsive hybrid nanocarriers
Published 2025-07-01“…Finally, in vivo targeting and anticancer studies demonstrated that FOL-RSV-LPHNCs selectively internalized to the cancerous region and suppressed the tumor volume with an 8.66-fold higher rate in the xenograft mouse model. The folate receptor-mediated uptake mainly facilitates this superior therapeutic response which was further confirmed by in silico molecular docking and dynamic simulation. …”
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2849
Physiological insights into the responses of tea plants to aluminum through an integrated transcriptomic and metabolomic analysis
Published 2025-07-01“…Compared to 0 mM Al treatment, low Al concentrations (0.4 mM) enhanced root vitality by 8.91%, while higher Al concentrations (10 and 100 mM) reduced root vigor by 19.31% and 76.81%, respectively. In a similar pattern, the electron transfer rate in leaves remained stable under low Al levels but significantly decreased under high Al conditions. …”
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2850
Impact of Malaria Diagnostic Technologies on the Disease Burden in the Sub-Saharan Africa
Published 2022-01-01“…However, in certain areas, the rate of decline has slowed or even reversed the gains made so far. …”
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2851
Identification of endothelial INSR as an osteosarcoma-related biomarker and therapeutic target based on weighted gene co-expression network analysis
Published 2025-08-01“…Abstract Background Osteosarcoma (OS) is the most common primary malignant bone tumor characterized by a high rate of metastasis. The clinical efficacy of current targeted drugs for OS is limited, highlighting the urgent need to identify novel therapeutic targets. …”
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2852
Evaluation and optimization simulation of land suitability for village construction in the urban rural integration zone empirical test based on 49 administrative villages in Chuzho...
Published 2025-04-01“…The results show that: (1) the village collective income and land use intensity have a great impact on the potential of village construction land, the proportion of permanent basic farmland, the distance from the organized town and the population loss rate have a great impact on the binding force of village construction land; (2) The proportion of suitable, unsuitable and suitable areas of village construction land is 38.63%, 27.56% and 15.60% respectively, the overall distribution pattern of suitability is “high in the east and southwest, South-Northeast Low”; (3) The eastern high-suitable area adopts the rural urbanization mode and optimizes the layout in a “group” style, The central low suitable area adopts the mode of “teng village and land reduction” and continuously improves the level of intensive land use, In the southwest, it is suitable for villages to form a “central village” layout mode based on location and economic development. …”
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2853
Effects of Bt Rice Straw Extract on Seed Germination and Plant Growth of Pakchoi: Novel Variables of Cropping System
Published 2025-06-01“…The 40 g·L<sup>−1</sup> heterozygous Bt extract increased leaf and root POD activity but inhibited germination rate and leaf SOD activity. The 10 g·L<sup>−1</sup> extract promoted root length and seedling POD activity but suppressed leaf POD activity. …”
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2854
Dr Papineau Meets Dr Masquelet—Management of Open Calcaneal Fractures, Combining Two Techniques: A Case Report
Published 2025-06-01“…Aim and background: Open fractures of the calcaneum are often the source of significant morbidity due to the high rate of wound infection and significant morbidity, ranging from malunion to amputation. …”
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2855
Fluid–solid coupling productivity analysis of multi-stage fractured horizontal wells in shale reservoirs
Published 2025-05-01“…The simulation results of the model align with actual field data, showing that gas production follows an “L-shaped” decline pattern with a coincidence rate exceeding 70%, verifying the model’s accuracy.…”
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2856
Safety and efficacy of prone position ventilation in patients with severe pneumonia in neurosurgical intensive care units
Published 2025-08-01“…PaO2 values followed a similar pattern:(79.63±4.81)mmHg,(89.90±6.83)mmHg,(106.98±12.26)mmHg,(130.40±12.03)mmHg and(135.68±13.95)mmHg,also demonstrating a significant increase(F=219.963,P<0.01). …”
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2857
Clinical characteristics and outcomes of non-tuberculous mycobacterial pulmonary infections after hematopoietic stem cell transplantation: A retrospective cohort study
Published 2025-07-01“…The most common radiologic pattern was nodular infiltrates in 15 (29.4%) patients. …”
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2858
Phytol nanoemulsions encapsulated alginate hydrogel beads for the protection and management of alcohol-induced gastric ulcer via nitric oxide synthase and NF-κB/IL-6/TGF-β modulati...
Published 2025-01-01“…Alginate beads showed a pH-dependent release pattern. The release behavior showed a higher release rate at pH 6.8 than at pH 1.2. …”
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2859
Cutis verticis gyrata in a Patient with Familial presenile sebaceous hyperplasia Presenting as &ldquo;Leonine facies&rdquo;: A Rare Case
Published 2025-06-01“…Familial presenile sebaceous hyperplasia (FPSH), a rare variant of sebaceous hyperplasia, follows an autosomal dominant inheritance pattern with incomplete penetrance and variable severity among family members. …”
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2860
Isokinetic knee strength as a predictor of cardiorespiratory responses during loaded aerobic capacity test in elite athletes
Published 2025-07-01“…Cardiorespiratory parameters—average breath volume (ABV), average breath frequency (ABF), auxiliary oxygen density (AOD), and heart rate (HR)—were recorded during the Bruce Protocol conducted under two conditions: unloaded and with a 10 kg loaded vest. …”
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