Outpatient acute kidney disease detection by national and institutional health data by Hsiu-Yin Chiang, Hung-Chieh Yeh, Zi-Han Lin, Bradley Chen, David Ray Chang, I-Wen Ting, Jie-Sian Wang, Yun-Lun Chang, Hung-Lin Chen, Yu-Chih Liu, Mei-Chuan Hsieh, Tzu-Ling Karen Tzeng, Chin-Chi Kuo

“…The criteria for AKDOPT were a >50% change in maximum and minimum serum creatinine levels or a >35% change in corresponding estimated glomerular filtration rate values within the 180 days before an appointed outpatient visit. …”
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Stomatal–Hydraulic Coordination Mechanisms of Wheat in Response to Atmospheric–Soil Drought and Rewatering by Lijuan Wang, Yanqun Zhang, Hao Li, Xinlong Hu, Pancen Feng, Yan Mo, Shihong Gong

“…We investigated wheat’s hydraulic transport (leaf hydraulic conductance, <i>K</i>_leaf) and gas exchange (stomatal conductance, <i>g_s</i>; photosynthetic rate, <i>A</i>_n) responses to combined drought stress from atmospheric and soil conditions at the heading stage, as well as rewatering 55 days after treatment initiation. …”
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The state of cancer care in Russia: breast cancer. Epidemiology and survival of patients. The impact of the SARS-CoV-2-beta-coronavirus epidemic (clinical and population study) by V. M. Merabishvili, V. F. Semiglazov, A. V. Komiakhov, T. Yu. Semiglazova, P. V. Krivorotko, А. M. Belyaev

“…The one-year and five-year survival rate of breast cancer patients continues to grow.…”
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Dual Task Interference in Young, Middle-Age and Older Adults During Different Functional Mobility Tasks: A Cross Sectional Study by Tamara R. L. P. Tolotti, Ana Paula O. Barbosa, João Vítor E. H. Szortyka, Adriana T. de Lemos, Felipe de S. Stigger

“…The time taken to complete the mobility tasks was measured, while performance on secondary tasks was assessed based on the CTT rate, number of errors (SCWT and DST), and rate of recalled words (SVFT). …”
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Efficacy of Tuina Versus the Proprioceptive Neuromuscular Facilitation (PNF) Technique in Patients With Nonspecific Chronic Neck Pain: Protocol for a Randomized Controlled Trial by Kaiqi Fan, Aicheng Wang, Hainan Gao, Ting Yu, Xiangyu Zhu

“… BackgroundNonspecific chronic neck pain (NCNP), characterized by a long course, a high recurrence rate, and a young age of onset, causes a huge economic burden. …”
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[Translated article] Fixation of adult femoral neck fractures: Retrospective comparison between cannulated screws and femoral neck system (FNS) by E. Guillén Botaya, Á. Soler García, J.L. Aparicio Martínez, A. Tejeda Gómez, F. Segura Llopis, A. Silvestre Muñoz

“…Results: No significant differences were found in age (p-value 0.32), fracture patterns (p-value 0.77), surgical delay (p-value 0.28), surgical time (p-value 0.226), length of hospital stay (p-value 0.921) and blood loss (p-value 0.086) between the two groups.A significantly higher overall complication rate was observed in the group treated with cannulated screws (p-value 0.004). …”
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Airway-microbiome-driven mechanisms of disease during optimised self-management: a lesson learned from mechanistic study of the Colour-COPD trial by Alice M Turner, Daniella Spittle, Karl Staples, David Cleary

“…Analysis of the microbial patterns, which would have been obtained from the respiratory microbiome, will be compared to antibiotic consumption for acute exacerbation of chronic obstructive pulmonary disease (days/year) steroid load (days/year and mg/year), acute exacerbation of chronic obstructive pulmonary disease rate, forced expiratory volume in 1 second and longitudinally within individuals to determine the impact of frequent courses of antibiotics at group and individual level. …”
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Glycogen depletion in astrocytes induces sex-dimorphic remodeling of astrocytic and synaptic structures with concomitant anxiety-like behaviors and maternal care deficits by Xiaotong Shi, Yuanyuan Zhu, Zhaoyichun Zhang, Ningcan Ma, Danyi He, You Wu, Ziyi Dai, Xinyan Qin, Yingyi Chen, Youyi Zhao, Haopeng Zhang, Jing Huang, Hui Zhang, Ze Fan

“…Maternal care was analyzed through pup retrieval assays and nest-building behavior, while offspring development was tracked via survival rates and ultrasonic vocalizations. Expression of hormonal receptors was identified via qPCR and immunofluorescence staining. …”
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Automatic mouse ultrasound detector (A-MUD): A new tool for processing rodent vocalizations. by Sarah M Zala, Doris Reitschmidt, Anton Noll, Peter Balazs, Dustin J Penn

“…We evaluated A-MUD error rates using manually segmented sound files as a 'gold standard' reference, and compared them to a commercially available program. …”
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Effect of transport stress on apoptosis and autophagy in goat lung cells by Yu Zhuo, Yunhai Hu, Yangshan Jin, Tian Ye, Yanzhen Yang, Ben Liu, Ben Liu, Ben Liu, Wenya Zheng, Wenya Zheng, Songlin Ding, Xue Yang, Xue Yang, Lucheng Zheng, Lucheng Zheng, Wei Hu, Wei Hu, Manxin Fang, Manxin Fang, Wanting Yi, Wenjing Xing

“…IntroductionRoad transportation exposes goats to thermal, mechanical, and microbial stressors that can compromise their welfare by triggering pulmonary apoptosis and autophagy processes associated with tissue damage and immunosuppression.MethodsTo explore potential biomarkers for transport-related welfare assessment, this study analyzed lung tissues from nine Ganxi goats (n = 9; 0 h control, 2 h/6 h transport groups) through an integrated experimental approach: TUNEL assays quantified apoptosis rates, immunohistochemistry mapped protein localization, Western blotting analyzed protein expression levels, and qPCR profiled gene expression of apoptotic regulators (Bax, Bcl-2) alongside autophagy-related markers (LC3B, p62, PINK1, Parkin).ResultsResults indicated time-dependent cellular stress patterns, where the 2 h group displayed elevated apoptosis rates, while the 6 h group exhibited upregulated Parkin expression (p &lt; 0.05) and altered regulation of apoptotic [Bcl-2-associated X-protein (Bax)/B-cell lymphoma-2 (Bcl-2)] and autophagy-related genes (Microtubule-associated protein 1 light chain 3B (LC3B), p62, PTEN-induced putative kinase 1 (PINK1)/Parkin). …”
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Chemoprevention of 4NQO-Induced Mouse Tongue Carcinogenesis by AKT Inhibitor through the MMP-9/RhoC Signaling Pathway and Autophagy by Panpan Yin, Jiahui Chen, Yanlin Wu, Feng Gao, Jinlin Wen, Wenbin Zhang, Ying Su, Xinyan Zhang

“…Oral cancer (OC), the most common cancer in the head and neck, which has a poor prognosis, histopathologically follows a stepwise pattern of hyperplasia, dysplasia, and cancer. Blocking the progression of OC in the precancer stage could greatly improve the survival and cure rates. …”
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Pod Production Dynamics and Pod Size Distribution of Theobroma cacao L. Clone CCN 51 in Full Sunlight by Ramón E. Jaimez, Luigy Barragan, Miguel Fernández-Niño, Oswaldo J. Larreal B, Byron Flores

“…During this period, 65% of the pods had lengths between 5 and 15 cm, which corresponds to the period of the highest pod growth rate. The average length values of the harvested pods were generally below 23 cm and rarely exceeded 7 pods/tree. …”
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SILENT MYOCARDIAL ISCHEMIA AND CARDIAC RHYTHM DISTURBANCES IN WOMEN WITH RHEUMATOID ARTHRITIS by D. S. Novikova, T. V. Popkova, A. N. Gerasimov, A. V. Volkov, E. I. Nasonov

“…Objective: to assess the rate of silent myocardial ischemia (SMI) and the pattern of cardiac rhythm disturbances in women with rheumatoidarthritis (RA), their association with traditional risk factors (TRF) for cardiovascular diseases (CVD), with subclinical structural and functionalchanges in the heart and vessels, with the activity and severity of rheumatoid inflammation.Subjects and methods. …”
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Relevance of Cellular Homeostasis-Related Gene Expression Signatures in Distinct Molecular Subtypes of Breast Cancer by Sharda P. Singh, Chathurika S. Dhanasekara, Michael W. Melkus, Chhanda Bose, Sonia Y. Khan, Flavia Sardela de Miranda, Maria F. Mahecha, Prrishti J. Gukhool, Sahil S. Tonk, Se-Ran Jun, Sahra Uygun, Rakhshanda Layeequr Rahman

“…Demographic factors such as age, race/ethnicity, menopausal status, and body mass index have been correlated with variations in incidence, mortality, and survival rates. Over the past decade, comprehensive genomic profiling has been widely used to identify molecular biomarkers and signatures to develop novel therapeutic strategies for patients. …”
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Multi-omics derivation of a core gene signature for predicting therapeutic response and characterizing immune dysregulation in inflammatory bowel disease by Mingming Wang, Liping Liang, Zibo Tang, Jimin Han, Lele Wu, Le Liu, Le Liu, Ye Chen, Ye Chen

“…Nomogram-based risk stratification effectively predicted biologic treatment responses across multiple therapeutic classes using four independent treatment datasets (GSE16879, GSE92415, GSE73661, GSE206285): low-risk patients demonstrated superior response rates to golimumab (63.3%), infliximab (54.8%), and vedolizumab (29% vs. 15% in high-risk group). …”
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End-of-Line Quality Control Based on Mel-Frequency Spectrogram Analysis and Deep Learning by Jernej Mlinarič, Boštjan Pregelj, Gregor Dolanc

“…This study presents a novel approach to the end-of-line (EoL) quality inspection of brushless DC (BLDC) motors by implementing a deep learning model that combines MEL diagrams, convolutional neural networks (CNNs) and bidirectional gated recurrent units (BiGRUs). The suggested system utilizes raw vibration and sound signals, recorded during the EoL quality inspection process at the end of an industrial manufacturing line. …”
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Multimodal analysis of cell-free DNA enhances differentiation of early-stage breast cancer from benign lesions and healthy individuals by Thi Tuong Vi Van, Trung Hieu Tran, Thi Hue Hanh Nguyen, Van Thien Chi Nguyen, Dac Ho Vo, Giang Thi Huong Nguyen, Trong Hieu Nguyen, Kim Sang To, Anh Luan Nguyen, Cao Hong An Tran, Thanh Xuan Jasmine, Thi Loan Vo, Thi Huong Thoang Nai, Thuy Trang Tran, My Hoang Truong, Ngan Chau Tran, Thi Loc Le, Thi Hong Nhung Nguyen, Ngoc Hieu Tu, Thanh Son Tran, Bao Toan Le, Van Phong Tang, Pham Thanh Nhan Nguyen, Khac Tien Nguyen, Van Chien Ho, Xuan Vinh Nguyen, Nhu Nhat Tan Doan, Thi Trang Tran, Thi Minh Thu Tran, Vu Uyen Tran, Minh Phong Le, Thi Luyen Vu, Ba Linh Tieu, Huu Tam Phuc Nguyen, Luu Hong Dang Nguyen, Ngoc Minh Phan, Thi Van Phan, Thi Thanh Thuy Do, Thi Huyen Dao, Hung Sang Tang, Duy Sinh Nguyen, Hoa Giang, Minh Duy Phan, Hoai-Nghia Nguyen, Duc Hieu Vo, Le Son Tran

“…Conclusions These findings underscore the potential of cfDNA biomarkers to enhance BC detection and reduce the rate of unnecessary biopsies.…”
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Brain-based gene expression and corresponding behavioural relevance of risk genes for broad antisocial behaviour by Jaroslav Rokicki, Megan L. Campbell, Dennis van der Meer, Alina I. Sartorius, Natalia Tesli, Piotr Jahołkowski, Alexey Shadrin, Ole Andreassen, Lars T. Westlye, Daniel S. Quintana, Unn K. Haukvik

“…Certain genes like NTN1, SMAD5, NCAM2, and CDC42EP3 displayed specificity for cognitive terms including chronic pain, heart rate, and aphasia. These expression patterns aligned with neurocognitive domains related to thinking, and learning, distress, motor skills, as determined by fMRI analysis. …”
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GROWTH PERFORMANCE AND PRODUCTIVITY OF RUBBER & PLASTIC PRODUCTS INDUSTRY IN PUNJAB by GULSHAN KUMAR

“…The growth of industry has been gauged in terms of variables - number of units, fixed investment, employment and production. Yearly growth rates have been computed to catch year- to- year fluctuations in growth and compound annual growth rates (CAGRs) have been worked out to ascertain the impact of the policies of liberalized regime on growth of this industry. …”
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An influence of a modulating signal starting phase on the modulation detection by A. P. SĘK, E. B. SKRODZKA

“…Data shown in this paper are consistent with predictions of models based on excitation pattern changes and with a concept according to which AM/FM detection at low modulation rates depends mainly on maximum and minimum values of signal amplitude/frequency. …”
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