Multi-Objective Optimization of Off-Grid E-Bikes Charging Stations Powered by PhotoVoltaics by Fabio Corti, Gabriele Maria Lozito, Davide Astolfi, Salvatore Dello Iacono, Antony Vasile, Marco Pasetti, Alberto Reatti, Alessandra Flammini

“…A Genetic Algorithm is employed to determine the most appropriate rated power of the installed PhotoVoltaic (PV) systems and of the energy storage, by incorporating statistical methods to estimate the daily number of e-bikes requiring charging, hence making the optimization process more reflective of actual usage patterns. …”
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Nutritional status, body indices, and somatotype in Aymara and Quechua children from high Andean areas of Peru by Lidia Sofia Caballero Gutiérrez, Rodolfo Adrian Núñez Postigo, Juber Chávez Dominguez, Vilma Lucrecia Tapia Aguirre, José Oscar Alberto Begazo Miranda

“…Infants born at high altitudes, such as in the Puno region, typically exhibit higher birthweights than those born at low altitudes; however, the influence of ethnicity on childhood anthropometric patterns in high-altitude settings remains poorly understood. …”
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Prevalence and associated factors of adherence to antihypertensive medication: a nationwide cross-sectional study by Muhammad Arshed, Mehwish Kiran, Muhammad Farooq Umer, Jamil Adnan Samkari, Syed Mehmood ul hassan, Shafqat Qamer, Ali Hassan Gillani, Sajid Hameed, Waseela Ashraf, Hasan Mujtaba, Muhammad Naseem Khan

“…Conclusion These findings highlight the complex interplay of demographics, medication patterns, and economic factors in medication adherence with very low adherence rates in Pakistan. …”
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Trends and disparities in tuberculosis burden in Kazakhstan and Mongolia (2017–2021): a comparative analysis using GBD metrics by Oyunzul Amartsengel, Malika Idayat, Alexander Rommel, Natalya Glushkova, Kairat Davletov, Malik Adenov, Naranzul Dambaa, Lkhagvasuren Khorolsuren, Elena von der Lippe

“…Research highlights the importance of assessing the impact of TB on global morbidity statistics, given its status as a prominent contributor to global morbidity rates and the cause of over a million deaths annually. …”
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A tale of two heatwaves: variable daily growth and a broad diet enable neustonic larval cabezon to thrive during warm oceanic conditions by Megan N. Wilson, Megan N. Wilson, Richard D. Brodeur, Toby D. Auth, G. Curtis Roegner, Cheryl A. Morgan, Samantha M. Zeman, Su Sponaugle

“…Findings include the first published measurement of larval cabezon daily growth rates. Mean growth rates were higher during MHWs, suggesting that elevated temperatures did not pose a major growth or survival challenge. …”
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Global burden of atrial fibrillation and atrial flutter due to high alcohol use from 1990 to 2021: estimates from the global burden of disease study 2021 by Xiaoming Wang, Changzheng Chen, Zhihua Yang, Yu Chen, Jun Fan, Renchun Tang, Yankun Shi, Lixia Yang

“…Methods We extracted GBD 2021 estimates on deaths, disability-adjusted life years (DALYs), and age-standardized rates (ASRs) for AF/AFL due to high alcohol use across 204 countries. …”
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Mutation Profiling of Premalignant Colorectal Neoplasia by Jakub Karczmarski, Krzysztof Goryca, Jacek Pachlewski, Michalina Dabrowska, Kazimiera Pysniak, Agnieszka Paziewska, Maria Kulecka, Malgorzata Lenarcik, Andrzej Mroz, Michal Mikula, Jerzy Ostrowski

“…HGD adenomas had significantly higher mutation rates than LGD adenomas, while LGD-H adenomas exhibited mutation frequencies similar to those of LGD adenomas. …”
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Intraspecific and Intracolonial Variation in the Profile of Venom Alkaloids and Cuticular Hydrocarbons of the Fire Ant Solenopsis saevissima Smith (Hymenoptera: Formicidae) by Eduardo Gonçalves Paterson Fox, Adriana Pianaro, Daniel Russ Solis, Jacques Hubert Charles Delabie, Bruno Cunha Vairo, Ednildo de Alcântara Machado, Odair Correa Bueno

“…Some fire ant species are top-rated pests spreading throughout the world by trade vessels. …”
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Unravelling molecular transformation of dissolved organic matter in the full quantization treatment of landfill leachate concentrate by ZHONG Quanfa, ZHONG Lin, XU Guohui, JIN Qinghai, YU Jin, XU Fei, HE Di

“…To investigate the removal and transformation patterns of dissolved organic matter(DOM) in the full quantization treatment of landfill leachate concentrate, this study centered on the landfill leachate concentrate derived from a waste transfer station in Shenzhen. …”
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Real-world effectiveness and safety of CDK4/6i in elderly and BIPOC patients with HR+/HER2- advanced/metastatic breast cancer: an updated systematic literature review by Nadia Harbeck, Adam Brufsky, Chloe Grace Rose, Beata Korytowsky, Connie Chen, Krista Tantakoun, Endri Jazexhi, Do Hoang Vien Nguyen, Meaghan Bartlett, Imtiaz A. Samjoo, Timothy Pluard

“…Key outcomes for synthesis were effectiveness, treatment patterns, and safety.ResultsThis review included 23 unique studies. …”
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Improvement of Oral Anticoagulant Prescription and Long‐Term Clinical Outcomes of Patients With Atrial Fibrillation After Implementation of a Clinical Decision Support System in Ou... by Po‐Tseng Lee, Mu‐Hsiang Huang, Ting‐Chun Huang, Pi‐Shan Sung, Chi‐Hui Hsu, Ya‐Ling Huang, Sheng‐Hsian Lin, Ping‐Yen Liu

“…Results OAC prescription rates increased from 47.3% to 67.5% after CDSS implementation. …”
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Exploring mobility data for enhancing HIV care engagement in Black/African American and Hispanic/Latinx individuals: a longitudinal observational study protocol by Katherine P Theall, Lisa Hightow-Weidman, Xiaoming Li, Sean Young, Lidia Flores, Seungjun Kim, Maryam Hassani, Cristina De Haro, Mohamed Emish, Zeyad Kelani, Dominic Arjuna Ugarte, Amanda Castel

“…We seek to study the relationship between mobility patterns and HIV care engagement.Ethics and dissemination Ethical approval has been obtained from the Institutional Review Board of the University of California, Irvine (#20205923). …”
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Lignin Unlocks Stealth Carbon Sinks in Cold Seeps via Microbial Enzymatic Gatekeeping by Jialing Li, Jingchun Feng, Pandeng Wang, Mengzhuo Zhu, Yongji Huang, Ying Wu, Junning Fan, Junlin Hu, Xiyang Dong, Yingli Zhou, Xuanyu Tao, Si Zhang

“…Although direct methanogenesis was undetected, methylotrophic potential was evidenced through methane cycle gene expression patterns by lignin decomposers. Phylogenetic surveys further demonstrated the global prevalence of lignin decomposers across 12 major cold seep systems. …”
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Nutritional status, dietary inflammatory potential, and risk of osteosarcopenia: the Bushehr Elderly Health (BEH) program by Gita Shafiee, Mehrad Nasiri, Zhaleh Shadman, Mehdi Ebrahimi, Narges Zargar Balajam, Ramin Abdi Dezfouli, Iraj Nabipour, Ramin Heshmat

“…Abstract Background Osteosarcopenia is a growingly approved geriatric condition with a significant prevalence that contributes to higher rates of illness and death. Chronic inflammation and inadequate nutrition are key risk factors for numerous age-related diseases. …”
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Seven New Irbesartan Salts: Significantly Improved Dissolution, Excellent Hygrothermal Stability, and Characteristic Supramolecular Synthons by Junxiao Wang, Chuanhua Wu, Menglong Zhang, Lingli Hou, Wei Chen, Dingding Jing, Ying Bao

“…Their vitro dissolution, intrinsic dissolution rates (<i>IDR</i>s), thermal/hygroscopic stability (via thermal analysis, dynamic vapor sorption, and accelerated stability tests), and phase transition process (monitored by in situ Raman spectroscopy) were evaluated. …”
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Ultrasound-activated miR-195-5p/shikonin nanobubbles remodel immunosuppressive microenvironment via immunogenic cell death to potentiate PD-1/PD-L1 blockade in hepatocellular carci... by Yandi Tan, Qiao Xu, Yezi Chen, Yun Liu, Chaoqi Liu, Xinwu Cui, Yun Zhao

“…Despite the transformative clinical impact of programmed cell death ligand 1/programmed death 1 (PD-1/PD-L1) blockade in hepatocellular carcinoma (HCC), therapeutic efficacy remains limited by the tumor immunosuppressive microenvironment (TIME), with objective response rates persistently below 20 %. To address this critical clinical challenge, we engineered ultrasound (US)-responsive lipid nanobubbles (NBs) co-encapsulating microRNA (miR)-195-5p and shikonin (SK) (designated miR-195-5p/SK-NBs), a dual-functional platform designed to synergize PD-L1 suppression with immunogenic cell death (ICD). …”
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Machine Learning-Based Intrusion Detection Systems for the Internet of Drones: A Systematic Literature Review by Mostafa Ogab, Sofiane Zaidi, Abdelhabib Bourouis, Carlos T. Calafate

“…Existing Intrusion Detection Systems (IDS) for IoD face several limitations, including high false positive rates, resource constraints of drones, limited adaptability to evolving attack patterns, and a lack of standardized datasets for benchmarking, despite ongoing research efforts. …”
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Global collaboration and innovation in malignant cerebral edema research: a bibliometric perspective by Xinhua Peng, Xinhua Peng, Rongrong Zhu, Ke Zhang, Jianghong Ji, Chuanguo Lv, Feng Feng, Feng Feng

“…AimMalignant cerebral edema (MCE) is a life-threatening complication of acute brain injuries, with mortality rates exceeding 80% in the absence of treatment. …”
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Profiles and kinetics of PgRNA and clinical characteristics in pregnant, postpartum, and non-pregnant women with chronic HBV infection by Genju Wang, Yandan Wu, Ziyue Zhang, Qiuchen Wu, Juan Tang, Ying Ji, Yan Wang, Guanlun Zhou, Minmin Yu

“…Moreover, the detection rates of pgRNA, DNA, and HBeAg varied significantly across the three stages and different treatment regimens in CHB women. pgRNA was highly correlated with HBeAg, and a moderate correlation was found between pgRNA and HBV DNA levels. …”
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fNIRS evidence of abnormal frontotemporal cortex activation and functional connectivity in depressed patients after stroke: neuromodulatory mechanisms from mild to moderate depress... by Shanshan Zhou, Xiaodie Liu, Mengyuan Chen, Wenyi Chen, Yawen Pan, Yinghao Zhi

“…In contrast, the mild-PSD group displayed no notable connectivity differences between the two groups.ConclusionThis study presents distinct patterns of frontotemporal cortex activation and functional connectivity alterations associated with varying severity levels of PSD. …”
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