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  1. 18521

    Electroacupuncture and Parecoxib Reduce Inflammatory Injury in a Primary Dysmenorrhea Rat Model: Investigating the Role of the COX-2/NF-κB/NLRP3 Pathway by Xue X, Wang S, Li J, Yuan H, Pan S, Liu X, Yue Z, Liu Y

    Published 2025-07-01
    “…Furthermore, EA markedly improved pain symptoms and pathological damage in PDM rats and downregulated the expression of COX-2/NF-κB/NLRP3 signaling pathway proteins in uterine tissue.Conclusion: Our findings demonstrated superior anti-inflammatory effects of EA + parecoxib on COX-2/NF-κB/NLRP3 signaling pathway-related proteins compared with that of EA alone or single-drug administration.Keywords: anti-inflammatory treatment, cyclooxygenase-2, prostaglandin, nuclear transcription factor, nucleotide-binding oligomerization domain-like receptor 3…”
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