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    The anti-depressive role of the Pei Yuan Kai Yu formula in cerebral small vessel disease based on gut microbiota by Lixuan Yang, Lixuan Yang, Yutian Ao, Yannan Li, Baoan Dai, Junnan Li, Wenzhe Duan, Kaiqiang Dong, Zhenyun Han, Rongjuan Guo

    Published 2025-06-01
    “…Pseudo germ-free rats were colonized with gut microbiota from high-salt-fed rats exposed to CUMS, followed by PY administration.ResultsIn rats with CSVD and depression, PY significantly increased body weight; alleviated depression-like behaviors; and decreased the levels of inflammatory cytokines such as TNF-α, IL-1β, and IL-6 in both serum and hippocampus. …”
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    Antiviral Activity of Benzydamine Hydrochloride against SARS-CoV-2 in vitro Model by V. V. Lebedeva, I. T. Fedyakina, O. E. Latyshev, E. I. Burtseva, I. V. Kukes, D. V. Blinov, O. V. Eliseeva, V. F. Larichev, T. M. Garaev, T. V. Grebennikova

    Published 2021-07-01
    “…Antiviral properties of benzidamine hydrochloride were studied in vitro in non-toxic concentrations on monolayer of Vero-E6 cells infected with pandemic strain of SARS-CoV-2 coronavirus in treatment and prophylactic scheme of the compound and virus administration.Results. Benzidamine hydrochloride has antiviral activity (15,0 mcg/ml), the efficiency of its antiviral action is directly proportional to the concentration of the substance.Conclusions. …”
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