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    Vancomycin wound penetration in open-heart surgery patients receiving negative pressure wound therapy for deep sternal wound infection by Martin Kolek, Jana Ďuricová, Hana Brozmanová, Pavel Šištík, Jan Juřica, Klára Kaňková, Oldřich Motyka, Ivana Kacířová

    Published 2025-12-01
    “…On the following three consecutive days, additional samples were collected, only before vancomycin administration.Results The ratio of average vancomycin concentration in wound exudate to in serum was higher for free (unbound) (1.51 ± 0.53) than for total (bound + unbound) (0.91 ± 0.29) concentration (p = 0.049). …”
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