The emerging role of next-generation sequencing in minimal residual disease assessment in acute lymphoblastic leukemia: a systematic review of current literature by Andreea-Iulia Ștefan, Andreea-Iulia Ștefan, Letiția-Elena Radu, Letiția-Elena Radu, Dumitru Jardan, Anca Coliță, Anca Coliță

“…Challenges such as high costs, complex bioinformatics analysis and the need for standardization remain. While its integration into clinical practice holds significant promise, further research is needed to establish standardized protocols, cost-effectiveness, and its optimal role in treatment decision-making. …”
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Determining mosquito age using surface-enhanced Raman spectroscopy and artificial neural networks: insights into the influence of origin and sex by Zili Gao, Yuzhen Zhang, Laura C. Harrington, Courtney C. Murdock, Elisabeth Martin, Dalton Manbeck-Mosig, Steve Vetrone, Nicolas Tremblay, Christopher M. Barker, John M. Clark, Lili He, Wei Zhu

“…However, traditional methods, such as tracheole morphology analysis, are labor-intensive and have limited scalability. …”
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Students’ motives for enrolling in the master of nursing program in Croatia despite degree recognition uncertainties: a cross-sectional study by Andrea Vuksa, Vesna Mijoc, Ivica Matic, Marta Civljak, Marin Cargo, Snježana Cukljek, Kata Ivanisevic, Mario Marendic, Zrinka Puharic, Natasa Skitarelic, Sanja Zoranic, Marijana Neuberg, Dijana Majstorovic, Alen Brecek, Ivana Barac, Livia Puljak

“…Most BN and MN students, while cognizant of the limited MN-recognized roles, were primarily motivated to enrol in MN programs to deepen knowledge (94%) and advance career opportunities. …”
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Predictors of long-term outcome of patients with schizophrenia in Africa: systematic review and meta-analysis by Mulualem Kelebie, Setegn Fentahun, Gebresilassie Tadesse, Girum Nakie, Girmaw medfu, Birtukan Fasil, Gidey Rtbey, Mulu Muche, Melese Gobezie, Abenet Alazar, Mamaru Melkam, Getasew Kibralew

“…Given the heterogeneity of outcomes, region-specific strategies are essential to optimize care.…”
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Independent and combined relationships between nighttime light exposure, air pollution, PM2.5 constituents, greenness and diabetes or high blood sugar: a national prospective cohor... by Siyu Qing, Ziyue Liang, Yifang Liang, Renfang Zhang, Xiaojie Chen, Wenqing Wang, Chunejie Xu, Fei Lin, Yongbin Wang

“…Methods Using data from the China Health and Retirement Longitudinal Study (CHARLS, 2011–2015), we included 11,865 participants aged ≥ 45 years without baseline D/HBS. …”
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Comparison of Factors Affecting Quality of Life in Patients with Acute Ischemic Stroke Across Different Stroke Severities by Yuxuan Lu, Weiping Sun, Yining Huang, Zhaoxia Wang, Zhiyuan Shen, Wei Sun, Ran Liu, Fan Li, Junlong Shu, Qing Peng, Jingjing Jia, Peng Sun, Yijun Song, Haiqiang Jin, CASTOR Investigators

“…The aim of this study was to address this critical issue, refining treatments to enhance long-term QoL and optimize resource use. Methods In this multicenter prospective study conducted in China, patients with AIS were assessed using the EuroQol-5 Dimension (EQ-5D) questionnaire at admission and 1 year later. …”
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Effectiveness of anabolic and anti-resorptive agents for preventing postmenopausal osteoporosis fractures: a systematic review and network meta-analysis by Peng Su, Maofu Li, Jian Xiao, Longbin Bai

“…We aimed to estimate anti-osteoporosis effect and compliance of different anabolic and anti-resorptive agents to explore the optimal cycling strategy. Methods PubMed, Embase, Web of Science, and Cochrane Library were searched for randomized controlled trials comparing anabolic or anti-resorptive agents with placebo or each other in postmenopausal women with osteoporosis or osteopenia, reporting outcomes on bone mineral density (BMD) change, fracture incidence, or treatment discontinuation from inception to February 1, 2024. …”
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From gaps to compliance: a 12-year retrospective cohort study of trends in mismatch repair protein testing and Lynch syndrome identification in colorectal cancer in Central Switzer... by Bettina Marturet Fendt, Celina Geiss, Muriel Elhai, Joachim Diebold, Alexander Vogetseder

“… STUDY AIM: Alongside an analysis of incidence trends in colorectal cancer and Lynch syndrome over time, the study sought to evaluate the implementation and trends of reflex testing for mismatch repair proteins and key mutations in relevant genes (BRAF, KRAS, NRAS) in colorectal cancer in Central Switzerland from 2011 to 2022, specifically assessing adherence to the Swiss Academy for Quality in Medicine (SAQM) guidelines, in order to identify any gaps or inconsistencies in testing practices that may hinder the diagnosis of Lynch syndrome or microsatellite instability, highlighting areas requiring improvements for optimal patient care. METHODS: This retrospective study enrolled 2602 patients with 2673 histologically confirmed colorectal cancers. …”
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Prediction of joint deformity after MIPPO with double reverse traction repositor based on Hounsfield units derived from CT scans by Guimiao Li, Kejia Shang, Shengnan Zhang, Zhongzheng Wang, Yanjiang Yang, Chunxu Fu, Chen Feng, Di Zhang, Yingze Zhang

“…Abstract Background Tibial plateau fractures (TPFs) account for approximately 1% of all fractures and notably 8% of fractures among the elderly. While both surgical and non-surgical interventions can yield promising short-term results, the long-term implications, particularly the risk of post-traumatic osteoarthritis (PTOA), necessitate further investigation. …”
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Vitamin D as a Key Mediator Between C-reactive Protein to Albumin Ratio and Congestive Heart Failure in an Elderly Population: An Innovative Exploration Using the NHANES Database by Yufeng Wei, Zhaofeng Zhang

“…Pearson correlation evaluated bivariate relationships between continuous variables (vitamin D, CAR), while Spearman correlation assessed associations between the dichotomous CHF status and continuous variables (vitamin D, CAR). …”
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Clinical course and approaches to therapy in kidney transplant recipients with the novel COVID-19 disease by O. N. Kotenko, L. Yu. Artyukhina, N. F. Frolova, E. S. Stolyarevich

“…Materials and methods. During the period from April 15, 2020 to June 15, 2020, 68 people (38 men and 30 women) were hospitalized at our clinic. …”
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Effectiveness of Radiomics-Based Machine Learning Models in Differentiating Pancreatitis and Pancreatic Ductal Adenocarcinoma: Systematic Review and Meta-Analysis by Lechang Zhang, Dewei Li, Tong Su, Tong Xiao, Shulei Zhao

“…MethodsPubMed, Embase, Cochrane, and Web of Science were searched for relevant studies up to June 29, 2024. …”
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IoT in urban development: insight into smart city applications, case studies, challenges, and future prospects by Sayeed Salih, Abdelzahir Abdelmaboud, Omayma Husain, Abdelwahed Motwakel, Hashim Elshafie, Mahir Sharif, Mosab Hamdan

“…Through the integration of sensors, cell phones, artificial intelligence (AI), data analytics, and cloud computing, smart cities worldwide are evolving to be more efficient, productive, and responsive to their residents’ needs. While the promise of smart cities has been marked over the past decade, notable challenges, especially in the realm of security, threaten their optimal realization. …”
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A Neural Network Model for Intelligent Classification of Distal Radius Fractures Using Statistical Shape Model Extraction Features by Xing‐bo Cai, Ze‐hui Lu, Zhi Peng, Yong‐qing Xu, Jun‐shen Huang, Hao‐tian Luo, Yu Zhao, Zhong‐qi Lou, Zi‐qi Shen, Zhang‐cong Chen, Xiong‐gang Yang, Ying Wu, Sheng Lu

“…Studies have shown that in emergency settings, the misdiagnosis rate of hand/wrist fractures can reach up to 29%, particularly among non‐specialist physicians due to a high workload and limited experience. While existing AI methods can detect fractures, they typically require large training datasets and are limited to fracture detection without type classification. …”
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Enhancing Youbike Redistribution System: A Study on Station Recommendation Using a Genetic Algorithm by Yang-Chou Juan, Yi-Chung Chen, Wei-Ting Chen, Chieh Yang, Chia-Tzu Liu, Yi-Ci Hou, Yi-Hsuan Tsai

“…A genetic algorithm then determined optimal station configurations and provided return station recommendations, considering user destinations and station dock ratios, while minimizing manual redistribution. …”
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Ultrasound-Assisted Enhancement of Gel Properties in <i>Hypomesus olidus</i> Surimi by Yuan Fu, Guochuan Jiang, Xing Sun, Shuibing Yang, Jiahang Yu, Xuejun Liu, Liyan Wang, Shuangjie Zhu

“…This study investigated the effects of ultrasonic power (100, 200, 400, 800 W) and time (5, 10, 15, and 20 min) on gel properties to establish optimal processing conditions. Results demonstrated that moderate ultrasonic treatment (200 W, 10 min) significantly enhanced gel quality, yielding a dense, uniform network with improved (<i>p</i> < 0.05) functionality: thr water-holding capacity increased by 35.88%, gel strength increased by 143.75%, and textural properties (hardness, cohesiveness, springiness, gumminess, chewiness) improved by 124.02%, 25%, 8.69%, 201.29%, 188.08% while maintaining color stability (1.59% whiteness increase). …”
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Sistem Pendukung Keputusan untuk Pemilihan Pupuk Padi Berbasis AHP dan Pembobotan ROC Dengan Pengujian User Validation by Mayang Anglingsari Putri, Risqy Siwi Pradini, Agung Setia Budi, Denisha Trihapningsari Trihapningsari

“…The goal of the research is to design and implement a DSS integrating AHP and ROC methods to provide optimal fertilizer recommendations based on the specific conditions of UD. …”
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Prediction of Rut Depth in Soil Caused by Wheels Using Artificial Neural Networks by N. Farhadi, A. Mardani, A. Hosainpour, B. Golanbari

“…The findings of this study hold significant practical implications, facilitating the development for the creation of more efficient agricultural practices, while simultaneously minimizing environmental impact. …”
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Vancomycin dosing in neonates: enhancing outcomes using population pharmacokinetics and simulation by Sílvia M. Illamola, Jiraganya (JJ) Bhongsatiern, Jiraganya (JJ) Bhongsatiern, Angela K. Birnbaum, Angela K. Birnbaum, Shaun S. Kumar, Joshua D. Courter, David B. Haslam, Karel Allegaert, Karel Allegaert, Karel Allegaert, David M. Reith, Pankaj B. Desai, Catherine M. Sherwin, Catherine M. Sherwin, Catherine M. Sherwin, Catherine M. Sherwin, Catherine M. Sherwin

“…Population pharmacokinetics (PopPK) models allow optimized dosing by incorporating neonatal-specific factors such as postmenstrual age (PMA), gestational age (GA), serum creatinine (SCr), and weight.ObjectiveTo develop optimized vancomycin dosing regimens for neonates that achieve an 80% probability of target attainment (PTA) for an AUC24/MIC ≥ 400 mg h/L across diverse clinical cohorts and simulated neonatal populations.MethodsReal-world data from three international centers (Belgium, New Zealand, USA), including 610 individuals and 2399 vancomycin concentrations, were used to externally evaluate a previously published PopPK model (NONMEM®). …”
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Topics of Study in Under-18 Padel Categories: A Scoping Review by Iván Martín-Miguel, Diego Muñoz, Rafael Conde-Ripoll, Álvaro Bustamante-Sánchez, Bernardino J. Sánchez-Alcaraz, Adrián Escudero-Tena

“…The findings suggest that a search-based teaching methodology enhances skill acquisition more effectively than traditional methods. Modifying the court dimensions (20 × 10 m to 10 × 6 m) and ball pressure optimizes learning in early training (~8–10 years). …”
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