Phosphatidylethanol and ethyl glucuronide to categorize alcohol consumption in alcohol-related cirrhosis by Benedict T.K. Vanlerberghe, Catalina Dumitrascu, Nele Van den Eede, Hugo Neels, Hannah van Malenstein, Tom J.G. Gevers, Matthijs Kramer, Lukas Van Melkebeke, Ad A.M. Masclee, Douwe de Boer, Schalk van der Merwe, Frederik Nevens, Alexander L.N. van Nuijs, Jef Verbeek

“…Here, we assessed the diagnostic accuracy and optimal detection windows of whole-blood PEth, uEtG, hEtG, and the novel biomarker fingernail ethyl glucuronide (nEtG), for different levels of alcohol use in patients with alcohol-related cirrhosis. …”
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Enhanced cement properties through plasma-activated water: Exploring hydration kinetics and microstructural refinement by Sattaya Chaiwithee, Kittiphat Kochchapong, Thaloengsak Keereemasthong, Pornchai Rachtanapun, Kittisak Jantanasakulwong, Jonghwan Suhr, Choncharoen Sawangrat, Pitiwat Wattanachai

“…Unlike conventional methods, plasma treatment of mixing water produces stable H2O2 reservoirs (up to 12.05 ppm at an optimal 4 L/min flow), which, upon decomposition in the alkaline cement environment, facilitate deep water penetration and sustained oxygen release throughout the cement matrix. …”
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<i>Chlorella vulgaris</i> as a Livestock Supplement and Animal Feed: A Comprehensive Review by Ishaya Usman Gadzama, Saraswati Ray, René Méité, Isaac Maina Mugweru, Takudzwa Gondo, Md Atikur Rahman, Md Rahat Ahmad Redoy, Md Fazle Rohani, Ahmed Eid Kholif, Md Salahuddin, Andre F. Brito

“…Additionally, CLV has shown promise in aquaculture, improving feed utilization, immunity, and disease resistance in various fish species. While CLV shows considerable potential, the variability in animal responses and the need for optimized inclusion levels necessitate further species-specific research to elucidate the long-term implications of its inclusion in animal diets.…”
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Residual stress and deformation analysis considering adhesive material properties to enhance manufacturing of HBM by Jaejin Jeon, Jeonghoon Song, Jun Young Oh, Seok Hwan Lee, Younghun Kim, Yun Ho Kim, Sam-Jong Choi, Sang Won Yoon

“…A sequential die-stacking method, employing the ‘Birth and Death’ function, simulated the actual HBM manufacturing process. …”
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Outcomes and predictive factors after second stereotactic radiosurgery for refractory trigeminal neuralgia by Bailey A. Loving, Jacob F. Oyeniyi, Siddharth Ramanathan, Joseph S. Lee, Hong Ye, Yastira Ramdas, Inga S. Grills, James F. Fontanesi, Prakash Chinnaiyan, Daniel K. Fahim, Daniel B. Michael, Peter Y. Chen

“…Future research should aim at optimizing treatment parameters to maximize pain relief while minimizing toxicity for these patients.…”
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Rules of acupoint and parameter selection for electrostimulation in treatment of functional dyspepsia based on bibliometrics by Dan WANG, Pei-jing RONG

“…Objective: To analyze the electrostimulation parameters and acupoint prescriptions for treatment of functional dyspepsia (FD) based on bibliometric methods. Methods: The relevant papers were searched from PubMed, Web of Science, Embase, China National Knowledge Infrastructure(CNKI), Wanfang Data, China Science and Technology Journal Database(VIP) and China Biology Medicine disc(Sinomed), dated from January 1st, 2010 to May 31st, 2023. …”
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Effect of Green Synthesized Fe₃O₄NP Priming on Alfalfa Seed Germination Under Drought Stress by Xinyue Wang, Mengting Ge, Xueqing He

“…These findings highlight that Fe₃O₄NPs synthesized via Ginkgo leaf extracts and enzymatic ultrasonic methods exhibit promising agricultural potential. …”
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The PANEN nomogram: clinical decision support for patients with metastatic pancreatic neuroendocrine neoplasm referred for peptide receptor radionuclide therapy by Aviral Singh, Aviral Singh, Aviral Singh, Sebastian Sanduleanu, Harshad R. Kulkarni, Thomas Langbein, Philippe Lambin, Richard P. Baum

“…A random survival forests (RSF) method was used to construct a model with an optimal number of clinical variables. …”
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Prognostic value of peripheral blood neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in patients with gastric cancer by ZHANG Le, LI Wei, HUANG Zeping, WANG Wenjie, CHEN Xiao

“…The Cox proportional-hazards model was used to evaluate risk factors for overall survival (OS) and progression-free survival (PFS). Kaplan-Meier method was used to conduct survival analysis, while log-rank test was used to evaluated the differences. …”
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Personalized Treatment Response in Progressive MS: Can the Patient's Profile Influence the Outcome? by Francesca Bovis, Ludwig Kappos, Sophie Arnould, Goeril Karlsson, Maria Pia Sormani

“…Identifying factors that predict individual treatment response is crucial for optimizing patient care, and this study aimed to demonstrate the feasibility (proof of concept) of applying a statistical method to predict individual treatment response in MS trials. …”
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Lipid liquid-crystalline nanoparticles as a suitable platform for accommodating sensitive membrane proteins: monitoring the activity of HMG-CoA reductase by Michalina Zaborowska-Mazurkiewicz, Ewa Nazaruk, Renata Bilewicz

“…These specific structural characteristics of the lipid nanoparticles were found optimal for enhancing the stability of HMGR. We characterized these hexosomes using dynamic light scattering (DLS), small-angle X-ray scattering (SAXS), and cryogenic electron microscopy (Cryo-TEM) methods, both with and without the encapsulated protein. …”
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Restoring Control: Real-World Success with Imipenem–Relebactam in Critical MDR Infections—A Multicenter Observational Study by Andrea Marino, Giuseppe Pipitone, Emmanuele Venanzi Rullo, Federica Cosentino, Rita Ippolito, Roberta Costa, Sara Bagarello, Ylenia Russotto, Chiara Iaria, Bruno Cacopardo, Giuseppe Nunnari

“…Statistical analysis involved descriptive methods and correlation analysis for mortality predictors. …”
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Global, regional, and national burden of maternal disorders, 1990–2021: a systematic analysis from the global burden of disease study 2021 by Jie Huang, Yuanyuan Man, Zan Shi, Xiaojie Fu, Wenhao Shi, Xiaoling Liang

“…The highest maternal mortality remained in low-SDI regions, with a substantial 63% decrease (51.85 to 19.44 per 100,000), while high-SDI regions showed minimal changes. Disease burden from hemorrhage, hypertensive disorders, and abortion declined significantly, while ectopic pregnancy saw stagnation. …”
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Blood Urea Nitrogen as a Predictor of Severe Acute Pancreatitis Based on the Revised Atlanta Criteria: Timing of Measurement and Cutoff Points by Suhan Lin, Wandong Hong, Zarrin Basharat, Qipin Wang, Jingye Pan, Mengtao Zhou

“…This study evaluated the prognostic accuracy of BUN for severe acute pancreatitis (SAP) and in-hospital mortality (IHM) in terms of the best timing for BUN measurement and the optimal BUN cutoff points. Methods. BUN determinants at the time of admission and 24 hrs after hospital admission were recorded and analyzed statistically. …”
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Joint Lagrangian Relaxation and Dynamic Programming Approach for a Multi-Period Multi-Product Location-Inventory Problem by Claudio Araya-Sassi, German Paredes-Belmar, Gabriel Gutierrez-Jarpa, Ricardo Gatica Escobar

“…Additionally, it involves setting order sizes and reorder points to minimize system costs while meeting service level conditions. This problem is structured as a non-convex mixed integer nonlinear programming model. …”
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Behavior and Analysis of Stainless Steel Wires Under Straight Bending by Erick-Alejandro González-Barbosa, Sergio-Alberto Hernández, José-Joel González-Barbosa, Héctor Castro-Mosqueda, Fernando Jurado-Pérez, José-Roberto Razo-Hernández

“…The study aimed to establish effective tools and methodologies for optimizing the bending process of metal wires, particularly focusing on the performance of SUS304 stainless steel in manufacturing torsion springs. …”
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Factors influencing clinical decision-making and health-related quality of life changes in colorectal cancer patients receiving targeted therapy: a multicenter study in China by Zeyang Li, Chengxi Feng, Hongwei Liu, Yin Liu, Huifang Xu, Yuqian Zhao, Xi Zhang, Yanqin Yu, Shaokai Zhang, Youlin Qiao

“…Abstract Objectives The aim of this paper is to assess the current clinical application of targeted therapy in colorectal cancer (CRC), identify factors influencing patients’ acceptance of targeted therapy, and evaluate its impact of targeted therapy on patients’ health-related quality of life (HRQoL). Methods This study was based on a national multi-center survey. …”
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Long-term straw return with moderate nitrogen levels reshapes soil bacterial communities in a vertisol by Zichun Guo, Rui Qian, Rui Qian, Rui Qian, Wei Li, Tianyu Ding, Tianyu Ding, Lei Gao, Lei Gao, Xinhua Peng

“…IntroductionIncorporating straw into the soil is a sustainable practice that can mitigate some of the adverse effects of excessive N fertilization on soil structure degradation and microbial diversity reduction.MethodsThis objective of this study was to determine the combined effects of straw management (straw return and straw removal) and N fertilization (0, 360, 450, 540, 630, and 720 kg N ha−1 yr.−1) on crop yields, soil properties, and soil microbial communities in a long-term wheat-maize cropping system.Results and discussionThe results showed that moderate N application (N450–N540) with straw return optimized wheat (283.5 kg ha−1) and maize (346.5 kg ha−1) yields, whereas higher N fertilization (N630, N720) led to soil acidification (pH decline of 0.51–1.67 units), irrespective of straw management. …”
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Dynamic control of upper limit for rainfall storing and effective use in rice paddies based on improved AquaCrop model by En Lin, Rangjian Qiu, Xinxin Li, Mengting Chen, Shizong Zheng, Fei Ren, Xiaoming Xiang, Chenglong Ji, Yuanlai Cui, Yufeng Luo

“…Yield losses across all scenarios remained below 3.00 %, confirming the strategy’s potential to optimize water management while minimizing adverse impacts on yield.…”
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Screening of Cellulase Producing Strains and Study on Their Enzymatic Properties by Shili WU, Yingying XIE, Xuening DUAN, Manshi YE, Weiqi XU, Guidong HUANG, Xianfeng ZHONG, Hong REN

“…The enzymatic properties of cellulase showed that: The optimal reaction temperature of extracellular cellulase was 50 ℃; the optimal pH was 5.5~6.5; the metal ions Cu2+, Ca2+, and Mg2+ had a promotional effect on the enzyme activity of three strains, of which Cu2+ had the strongest promotional effect, while Fe2+, Mn2+, Fe3+, and Ni+ had a different effect on the enzyme activity. …”
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