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5601
Risk Factors for Acute Exacerbation in Patients with COPD Group E in Ningbo: Risk Analysis of Irregular Review, Cardiovascular Complications, and Lung Function Decline
Published 2025-08-01“…These results may reduce medical resource utilization and AE frequency while improving quality of life, thereby informing evidence-based COPD management strategies and optimizing chronic disease care and resource allocation.Keywords: COPD, intervention management, risk factors, regular review, acute exacerbation, high risk…”
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5602
Unraveling the role of GPCR signaling in metabolic reprogramming and immune microenvironment of lung adenocarcinoma: a multi-omics study with experimental validation
Published 2025-06-01“…BackgroundLung adenocarcinoma (LUAD) is characterized by metabolic and immune heterogeneity, driving tumor progression and therapy resistance. While G protein-coupled receptors (GPCR) signaling is known to regulate metabolism and immunity in cancers, its role in LUAD remains poorly defined. …”
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5603
Impact of obesity on proteomic profiles of follicular fluid-derived small extracellular vesicles: A comparison between PCOS and non-PCOS women
Published 2025-06-01“…Correlation analysis revealed significant associations between specific differentially expressed proteins and IVF/ICSI outcomes, while a protective role for Heat Shock Protein 90 Beta Family Member 1 (HSP90B1) protein was observed in the non-PCOS group. …”
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5604
Performance evaluation of a medium axial field-of-view sparse PET system based on flat panels of monolithic LYSO detectors: a simulation study
Published 2025-05-01“…We simulate the performance of two flat-panel PET configurations: one with a fully populated 106 cm AFOV and another cost-efficient design featuring a reduced AFOV with axial gaps and vertical panel motion optimized for head and torso imaging. Methods Both configurations consist of two monolithic LYSO-based flat panels placed 50 cm apart. …”
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5605
Adjuvants and rebound pain following peripheral nerve block in adult surgical patients: a systematic review and network meta-analysis of randomized controlled trials
Published 2025-06-01“…Conclusion Current evidence, albeit of low quality, indicates that IV dexamethasone is the most effective adjuvant for the prevention of rebound pain, while PN dexamethasone is optimal for delaying its onset. …”
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5606
Identification of Th1-polarized Th17 cells: solving the problem
Published 2023-06-01“…However, the development of this direction is complicated by the weak comparability of data on the size of such a population. The analysis of methods for determining Th1-polarized Th17 in vivo and in vitro, carried out in this work, made it possible to resolve these contradictions and develop optimal approaches to identifying this population. …”
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5607
Improved clinical outcomes with a modified warming protocol in donor oocyte cycles
Published 2025-08-01“…Abstract Background Recent studies have attempted to improve laboratory efficiency while preserving clinical outcomes by shortening the time to warm cryopreserved embryos, though it is still unclear for oocytes. …”
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5608
The role of Pan-Immune inflammation value and systemic Immune-Inflammation index as potential biomarkers in predicting infectious complications following retrograde intrarenal surg...
Published 2025-07-01“…Abstract Background To predict postoperative infectious complications by utilizing hemogram parameters and derived inflammation indices and to analyze patient-related risk factors to propose a nomogram. Methods The data of patients who underwent retrograde intrarenal surgery were reviewed. …”
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5609
Is cooperation better than competition? Evidence from patient mobility before and after the COVID-19 pandemic in Tuscany, Italy
Published 2025-07-01“…Tuscan patients were more likely to escape to non-border regions for HS DRGs while for Musculoskeletal Diseases (in 2019 OR: 0.76; 95%CI: 0.68–0.84; in 2022 OR: 0.83; 95%CI: 0.72–0.89) they were less likely to be admitted to non-border regions for HS DRGs (p < 0.05).ConclusionThe findings highlight the need to implement interregional agreements to optimize patient mobility, avoid duplication of services, reduce costs and improve access to care.…”
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5610
Contribution of inflammation to heart failure development in human immunodeficiency virus-infected patients
Published 2022-03-01“…The first group included 37 HIV-infected patients with HF and blood CRP <15 mg/l, while the second group — 63 HIV-infected patients with HF and CRP concentration ≥15 mg/l. …”
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5611
Antibiotic treatment for 7 days versus 14 days in patients with uncomplicated bloodstream infections: a Systematic review and meta-analysis of randomized controlled trials and tria...
Published 2025-08-01“…BackgroundThe optimal duration of antibiotic therapy for bloodstream infections (BSI) remains a topic of ongoing debate. …”
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5612
Reevaluating Backup Monitor Chamber Tolerances for Stereotactic Body Radiotherapy Treatments using Volumetric-modulated Arc Therapy
Published 2025-04-01“…In addition, minor variations in gantry angles (up to 0.2%) slightly affected MU2 readings, while field size had no significant impact. Conclusions: The current 2% constancy tolerance may not be optimal for SBRT treatments on the Elekta Infinity accelerator. …”
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5613
Multi-scenario dynamic analysis of demand for critical minerals in China’s new energy vehicles under “dual carbon” goals
Published 2025-07-01“…Under identical “dual carbon” policy scenarios, new energy vehicles adopting high-nickel and nickel-cobalt-aluminum battery technologies had higher demand for nickel, while those using low-nickel alternatives had higher demand for cobalt. …”
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5614
Effects of adding dietary bakery waste to corn on broiler growth performance, carcass traits, and feed costs
Published 2025-02-01“…Future research should optimize bakery waste inclusion levels to ensure economic feasibility while maintaining meat quality.…”
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5615
Binder Jetting for Functional Testing of Ceramic Sanitaryware
Published 2025-05-01“…The results indicate that compositions containing calcined alumina exhibited lower pyroplastic deformation, while optimized gelling agent concentrations improved green strength and dimensional accuracy. …”
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5616
Electrochemical performance and behavior of nickel pig Iron anodic electrolysis for enhanced sulfuric acid leaching
Published 2025-08-01“…This study presents an innovative electrochemical method for producing ultra-fine Nickel Pig Iron (NPI) powders through anodically induced overpotential electrolysis, achieving a significantly high surface area and exceptional sulfuric acid leaching efficiency. …”
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5617
Effect of Temperature on the Physiological Response of Enhalus acoroides Seedlings
Published 2023-09-01“…The highest anatomical size of leaf tissue in the upper and lower epidermis was observed at 31°C, while the most extensive mesophyll tissue was observed at 35°C. …”
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5618
Analysis of surface roughness and machining performance of AZ91 magnesium alloy cut by WEDM
Published 2025-07-01“…For this purpose, an analysis of variance (ANOVA) and Grey Relational Analysis (GRA) were performed to find the optimal settings. Findings indicate that pulse-on time (Ton) significantly affects both MRR and SR: higher Ton increases MRR but worsens SR, while shorter Ton improves SR but reduces MRR. …”
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5619
3D-printed copper-containing tailored titanium alloys with corrosion resistance, biocompatibility, and anti-inflammatory properties for enhanced guided bone regeneration
Published 2025-08-01“…Titanium mesh, widely utilized in GBR procedures, faces a high exposure rate that leads to infections and compromised clinical outcomes. While 3D-printed personalized meshes have reduced exposure rates, infection risks persist, necessitating the development of bioactive solutions.MethodsIn this study, selective laser melting (SLM) was employed to fabricate copper-bearing titanium meshes using Ti-xCu powders (x=0, 4, 6, 8 wt%). …”
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5620
Influence of Mud Content on Mechanical Properties and Microstructure of Cemented Sand and Gravel
Published 2025-06-01“…When the mud content increased to 6.97%, the elastic modulus decreased by 46.3% compared to the optimal group. Strength was age-dependent: compressive strength increased continuously (with an increase of >20% in each stage), while the growth rate of splitting tensile strength slowed after 28 days, stabilizing at 8%-11% of the compressive strength. 2. …”
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