Safety, efficacy, and cost-effectiveness evaluation of systemic treatments for refractory colorectal cancer: a systematic review and modeling study by Mingye Zhao, Yunlin Jiang, Taihang Shao, Wenxi Tang

“…Abstract Objectives To conduct pooled estimates and comparative evaluations of safety and efficacy, alongside cost-effectiveness and value-based pricing analyses, for systemic treatments recommended by the National Comprehensive Cancer Network in refractory colorectal cancer. Methods A comprehensive search for related randomized controlled trials was conducted on PubMed, EMBASE, the Cochrane Library, and ClinicalTrials.gov. …”
Get full text

Temperature-based protection of biochemical and biomechanical characteristics during 25 kGy 60Co irradiation for allograft tendons by Yanlin Wan, Dayong Liu, Xiaolong Wang, Limin Wang, Rongxing Ma, Zhao Jiang, Wenjing Li, Bing Gao, Jingyu Zhang, Yongcheng Hu

“…Abstract Background While prior studies have investigated cryopreservation, cross-linkers, and radical scavengers for tendon irradiation protection, optimal implementation protocols remain underexplored. …”
Get full text

Calcium oxide nanoparticles from eggshell waste: A green nanotechnological strategy for microwave-assisted environmental clean up by Jannatun Zia, Amit Kumar Shringi, Ufana Riaz

“…XRD confirmed high crystallinity with an average crystallite size of 32 nm, while TEM revealed cubic nanoparticles in the range of 30–50 nm. …”
Get full text

Comparison of adverse events, prescription medication, and costs after hip, knee, and shoulder total joint arthroplasty: a retrospective cohort study by Maggie E. Horn, Steven Z. George, Anna Giczewska, Brooke Alhanti, Irene L. Tanner, Michael P. Bolognesi

“…Methods We conducted a retrospective cohort study of multi-payor claims data with patients (n = 2416) who underwent hip (n = 909), knee (n = 1250), or shoulder (n = 257) TJA within an academic health system. …”
Get full text

Development and Characterization of an Injectable Alginate/Chitosan Composite Hydrogel Reinforced with Cyclic-RGD Functionalized Graphene Oxide for Potential Tissue Regeneration Ap... by Mildred A. Sauce-Guevara, Sergio D. García-Schejtman, Emilio I. Alarcon, Sergio A. Bernal-Chavez, Miguel A. Mendez-Rojas

“…In vitro assays assessed fibroblast viability (MTT) and macrophage <i>TNF-α</i> secretion (ELISA), while ex-vivo injectability and retention were evaluated using chicken cardiac tissue. …”
Get full text

An Evolutionary Deep Reinforcement Learning-Based Framework for Efficient Anomaly Detection in Smart Power Distribution Grids by Mohammad Mehdi Sharifi Nevisi, Mehrdad Shoeibi, Francisco Hernando-Gallego, Diego Martín, Sarvenaz Sadat Khatami

“…Statistical <i>t</i>-tests confirm the superiority of DRL-NSABC over other algorithms, while achieving a variance of 0.00014. Moreover, DRL-NSABC demonstrates the fastest convergence, reaching near-optimal accuracy within the first 100 epochs. …”
Get full text

Analysis of RCCI engine characteristics with n-butanol/gasoline as low reactive fuel and biodiesel blend as high reactive fuel by Negasa Tesfaye Tefera, Ramesh Babu Nallamothu, Getachew Alemayehu

“…These findings provide important insights into fuel optimization and emission reduction methods for RCCI applications, advancing cleaner and more sustainable engine technologies.…”
Get full text

A novel framework for neutron-gamma density logging: semi-empirical modeling, directional neutron sources, and experimental benchmarking by Abolfazl Rafizade, Seyed Abolfazl Hosseini

“…This study proposes a novel NGD logging method that utilizes a directional neutron source to enhance measurement precision while reducing the number of required detectors. …”
Get full text

Radiomics features from the peritumoral region can be associated with the epilepsy status of glioblastoma patients by Yeong Chul Yun, Yeong Chul Yun, Yeong Chul Yun, Johann M. E. Jende, Johann M. E. Jende, Katharina Holz, Katharina Holz, Sabine Wolf, Sabine Wolf, Freya Garhöfer, Freya Garhöfer, Anja Hohmann, Philipp Vollmuth, Martin Bendszus, Heinz-Peter Schlemmer, Felix Sahm, Felix Sahm, Sabine Heiland, Wolfgang Wick, Varun Venkataramani, Varun Venkataramani, Felix T. Kurz, Felix T. Kurz, Felix T. Kurz

“…Three hundred thirty-six patients reported no epilepsy, while 115 patients were diagnosed with symptomatic epilepsy. …”
Get full text

Cell death pathway regulation by fatty acid metabolism-related genes in neuroblastoma: a multi-omics analysis identifying CHD5 as a novel biomarker by Yankun Chen, Junzhi Liu, Yubin Jia, Jiaxing Yang, Yan Jin, Yun Liu, Benfu Zhong, Qiang Zhao

“…Methods Identifying molecular subtypes influenced by fatty acid metabolism were built by consensus clustering analysis. …”
Get full text

Dietary supplement use in high-intensity functional training (HIFT) athletes by competition level by Jack Livingston, Sofea Smith, Kworweinski Lafontant, Claudia Gonzalez, Michelle Da Silva Barbera, Linh Nguyen, Susan Kampiyil, Jeffrey R. Stout, David H. Fukuda

“…High Intensity Functional Training (HIFT) is a unique sport with muscular strength/power/endurance, aerobic endurance, and rehydration concerns. While a multitude of DS may be beneficial for HIFT athletes, yet usage patterns unclear.Methods Forty-nine HIFT athletes (24 women, 25 men; Age = 37.8 ± 10.5 years; BMI = 25.7 ± 3.7 kg/m2) completed a supervised Qualtrics cross-sectional survey. …”
Get full text

Utilization of Benchtop Next Generation Sequencing Platforms Ion Torrent PGM and MiSeq in Noninvasive Prenatal Testing for Chromosome 21 Trisomy and Testing of Impact of In Silico... by Gabriel Minarik, Gabriela Repiska, Michaela Hyblova, Emilia Nagyova, Katarina Soltys, Jaroslav Budis, Frantisek Duris, Rastislav Sysak, Maria Gerykova Bujalkova, Barbora Vlkova-Izrael, Orsolya Biro, Balint Nagy, Tomas Szemes

“…<h4>Objectives</h4>The aims of this study were to test the utility of benchtop NGS platforms for NIPT for trisomy 21 using previously published z score calculation methods and to optimize the sample preparation and data analysis with use of in silico and physical size selection methods.…”
Get full text

Biofloc Technology (BFT) in Aquaculture: What Goes Right, What Goes Wrong? A Scientific-Based Snapshot by Mohammad Hossein Khanjani, Moslem Sharifinia, Maurício Gustavo Coelho Emerenciano

“…However, with further training, research, and innovation, these challenges can be overcome, and BFT can become a more widely understood and adopted technique, acting as an effective method for sustainable aquaculture. In summary, BFT offers a cleaner production option that promotes circularity practices while enhancing performance and economic benefits. …”
Get full text

Efficient federated graph aggregation for privacy-preserving GNN-based session recommendation by Jing Lou, Cheng Rong, Hanshen Chen, Daxue Liu

“…Results show that our method obtains state-of-the-art performance compared to existing adaptive FL methods while retaining the comparable performance of the centralized methods.…”
Get full text

Configuring adaptive PID-controllers of the automatic speed control system of the GTE by K. E. Chertilin, V. D. Ivchenko

“…This is conditioned by two factors: the complexity of solving the problem as a whole and the presence of a large number of technically diverse situations that need to be adapted and optimized. …”
Get full text

Mechanism of Influence of Spatial Perception on Residents’ Emotion in Child-Friendly Urban Streets of Fuzhou City by Shaofeng CHEN, Zhengyan CHEN, Yuhan XU, Zheng DING

“…Areas such as Academy Road in Gulou District are optimized for visual diversity and exhibit higher emotion scores. …”
Get full text

Factors associated with clinician adherence to guidelines for postpartum care: results from a California survey by Sylvia Guendelman, Serena Xinzi Wang, Maureen Lahiff, Hayley E. Miller, Lawrence Lurvey

“…Abstract Background In 2018, the American College of Obstetricians and Gynecologists (ACOG) issued multiple recommendations to optimize care within the first 12 weeks postpartum. …”
Get full text

Development status and key technologies of deep-sea towing autonomous underwater vehicles by Guanyu LU, Tiedong ZHANG, Zhenglin LI, Dapeng JIANG, Ming LEI, Wanzhen LUO

“…Modeling flexible bodies is key to accurate analysis, and combining multi-body dynamics, finite element method (FEM), and computational fluid dynamics (CFD) methods is a future trend. …”
Get full text

Analisis Penerimaan Pengguna Learning Management System (LMS) BRONE di Universitas Brawijaya berdasarkan Model Unified Theory of Acceptance and Use of Technology (UTAUT) by Lintang Trisnadi, Intan Sartika Eris Maghfiroh, Mochamad Chandra Saputra

“…Upaya sosialisasi dan pelatihan penggunaan LMS BRONE juga diperlukan agar adopsi sistem ini lebih optimal di kalangan pengguna.   Abstract In the era of information technology development, new learning methods have emerged, offering different perspectives on educational concepts. …”
Get full text

EEG microstate analysis in children with prolonged disorders of consciousness by Yi Zhang, Zhichong Hui, Yuwei Su, Weihang Qi, Guangyu Zhang, Liang Zhou, Jiamei Zhang, Kaili Shi, Yonghui Yang, Lei Yang, Gongxun Chen, Sansong Li, Mingmei Wang, Dengna Zhu

“…Abstract Prolonged disorders of consciousness (pDoC) in children lack objective and effective diagnostic methods to assess consciousness states, hindering targeted treatment selection and delaying recovery. …”
Get full text