LAPAROSTOMY IN EMERGENCY SURGERY by Ярослав Миронович Лещишин, Андрей Игоревич Баранов, Константин Владимирович Потехин, Александр Анатольевич Мартынов, Сергей Александрович Ярощук

“…Laparostomy, as a technical method of completing the surgical manual has been used by surgeons for a long time. …”
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What is the best first-line combination regimen for advanced EGFR-mutated non-small cell lung cancer: a network meta-analysis and systemic review by Chuang Yang, Yunfei Wang, Yiyong Sun, Ying Sun, Rongyu Zhang, Chengjun Wang, Yanan Song, Wen Zhao, Jisheng Li

“…In patients with brain metastases, osimertinib plus chemotherapy appeared to offer clinical benefits over other treatment strategies, although statistical significance was only observed in comparison with osimertinib monotherapy.ConclusionThis network meta-analysis suggests osimertinib plus pemetrexed-based chemotherapy as the only regimen demonstrating PFS benefits in the whole cohort and almost all the subgroup analyses, making it the optimal treatment for patients with advanced EGFR-mutated NSCLC. …”
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Leveraging ultrasonic-derived phenotypes and estimated breeding value to improve abdominal fat weight prediction in chickens throughout the egg laying period by Penghao Li, Zhengda Li, Fan Ying, Dan Zhu, Dawei Liu, Xianyi Song, Jie Wen, Guiping Zhao, Bingxing An

“…Abdominal fat (AF) in hens impacts egg production and may reflect poor feed efficiency, meaning that dynamic monitor of AF changes facilitate to optimize feeding management and production efficiency. …”
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Multi-dimensional Exposure Characteristics and Health Benefits Differentiation of Green Spaces within Community Life Circle by Hailin HONG, Qing CHANG

“…Identifying the health benefits and differentiation of diverse urban green space exposure characteristics within community life circle can address relative evidence gaps while informing more precise, effective planning strategies for practical applications.MethodsThis research employs a case study of Beijing’s central urban area, utilizing random forest model integrated with Shapley additive explanation (SHAP) to quantify the relative contribution of multi-dimensional UGS exposure characteristics to health benefits. …”
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The application of PET/CT with 18F-FDG in the differential diagnosis of lung solitary lesions by G. V. Afonin, A. E. Glukhareva, E. I. Smolenov, I. V. Kolobaev, E. E. Beketov, L. O. Petrov, S. A. Ivanov

“…All patients underwent PET / CT with 18fluoro‑2deoxy-D-glucose in the "whole body" mode in accordance with the standard protocol. …”
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CT-based radiomics model to predict platinum sensitivity in epithelial ovarian carcinoma: a multicentre study by Mengge He, Rahul Singh, Mandi Wang, Grace Ho, Esther M. F. Wong, Keith W. H. Chiu, Anthony K. T. Leung, Ka Yu Tse, Philip P. C. Ip, Andy Hwang, Lujun Han, Elaine Y. P. Lee

“…The whole tumour volume was manually segmented on the baseline ceCT. …”
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Current status of nurses’ public health emergency response capacity for emerging infectious disease: a cross-sectional study by Qin Qiu, Qin Qiu, Yuntong Liu, Fanping Meng, Fanping Meng, Xinhua Wang, Chunxiang Su

“…ObjectivesThis study aimed to assess the current status of nurses’ public health emergency response capacity for emerging infectious diseases (EIDs) in tertiary hospitals in Beijing, explore the deficiencies of nurses’ emergency response capacity, and analyze the influencing factors in the post-epidemic era.MethodsA convenience sampling method was utilized to recruit registered nurses in 3 tertiary hospitals in Beijing from 27 August and 2 September 2024. …”
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Biomechanical comparison of three tibial tunnel positions for PCL reconstruction: a 3D finite element analysis by Siman Tian, Yi Zheng, Yubin Long, Yingzhen Niu, Zhikuan Li, Jiangtao Dong

“…Methods This is a study limited to computational simulation and based on data from a single anatomical model. …”
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Long-Range LiDAR Vehicle Detection Through Clustering and Classification for Autonomous Racing by Na-Young Lim, Tae-Hyoung Park

“…While some methods have been proposed to address this limitation, they often neglect real-time processing, making them unsuitable for racing environments. …”
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Design, Synthesis, Anticancer Evaluation and Molecular Docking of Pyrimidine, Pyrido[4,3-d]pyrimidine and 5,6,7,8-Tetrahydropyrido[3,4-d]pyrimidine Derivatives as Novel KRAS-G12D I... by Hailong Yang, Lu Gan, Huabei Zhang

“…<b>Background</b>: KRAS-G12D mutations drive 20–50% of pancreatic/biliary cancers yet remain challenging to target due to GTP-pocket conservation and high cellular GTP levels. While allosteric inhibitors targeting the SWII pocket (e.g., MRTX1133) show promise, limited chemical diversity and paradoxical cellular/enzymatic activity relationships necessitate the exploration of novel scaffolds. …”
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Factors influencing the cure of pseudolithiasis: a retrospective study of 264 patients by Leijiao Deng, Jie Deng

“…Abstract Objective To identify independent predictors of complete resolution in patients with pseudobiliary calculi and evaluate the effectiveness of different therapeutic strategies. Methods Clinical data were retrospectively analyzed from 264 patients with pseudobiliary calculi admitted to The First Hospital of Lanzhou University between January 2018 and December 2019. …”
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In Vivo pharmacokinetic interactions of ribociclib with rivaroxaban and apixaban in rats: implications for increased drug exposure and dose adjustments by Zihan Liu, Zihan Liu, Wenyu Du, Wenyu Du, Qimin Wang, Zhi Wang, Jing An, Yinling Ma, Zhanjun Dong, Ying Li

“…This study aimed to evaluate the extent of DDIs between ribociclib and rivaroxaban or apixaban in rats and to explore the optimization of drug dosing strategies.MethodsMale Sprague-Dawley rats were divided into 9 groups (n = 6), receiving ribociclib, apixaban, rivaroxaban, ribociclib with rivaroxaban, ribociclib with apixaban, and combinations with reduced doses and time intervals. …”
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Advantages, applications, and future directions of in vivo aptamer SELEX: A review by Minchuan Lyu, Chi Ho Chan, Ziqi Chen, Yumeng Liu, Yuanyuan Yu

“…Unlike traditional in vitro methods that often fail to capture the complexity of biological interactions in physiological environments, in vivo SELEX leverages whole living organisms as selection targets. …”
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Alzheimer's disease recognition via long-range state space model using multi-modal brain images by Ziyin Ren, Meng Zhou, Sadia Shakil, Raymond Kai-Yu Tong

“…The FF-LSSM can extract whole-volume features at every scale and effectively decide their global dependencies via adopted 3D Mamba encoders. …”
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Angular Stabilization of a Multirotor Aircraft in Venus’ Atmosphere by Vladislav V. Ryzhkov

“…A PID controller is used for attitude stabilization, with its parameters optimized using the Nelder-Mead method in combination with numerical integration of the equations of motion. …”
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Circular economy impact on global sustainable growth in international industrial business by Olesia Suntsova

“…The proposed recommendations for improving the efficiency of implementing circular models can be used by industrial enterprises to optimize their production processes. Implementing circular models not only contributes to the economic growth of international enterprises but also improves the environmental situation, positively impacting society as a whole. …”
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Influencing Factors on Oyster Recruitment and Performance Evaluation for Oyster Reef Restoration in Tianjin Coastal Zones by Yuxuan Zhao, Chen Yang, Bo Zhang, Yanping Li, Jianbo Tu, Fuxin Niu, Wenliang Kong, Zhiyun Wang, Xianhua Liu

“…Our results demonstrated that the shell string method was the most effective in the Dashentang subtidal zone, while the mesh bag method with oyster seeding was optimal in the Bagua Shoal intertidal zone. …”
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Thermo-hydro-mechanical coupling mechanisms and sensitivity analysis of abandoned mine thermal energy storage systems by Liyuan LIU, Yaohui LI, Tao WANG, Tongbin ZHAO, Qiang KOU, Zerui MI, Le ZHANG

“…Given the extensive abandonment of mines in China, the abundant non-mineral resources exposed in derelict mine workings pose challenges in addressing idle mine risks while also presenting opportunities for improving energy infrastructure. …”
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Pitfalls in the diagnosis of apparent homozygous mutations: two cases of IL10RA deficiency inflammatory bowel disease and a literature review by Xiu Shi, Ziqing Ye, Lai Qian, Wenhui Hu, Ye Yang, Chunmeng He, Zhiheng Huang, Bingbing Wu, Ying Huang

“…This report emphasizes the importance of optimizing the genetic analysis workflow, especially when there is doubt about the initial whole exome sequencing results.…”
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Decoding the Dynamics of the Distribution of Blood Components in a Tertiary Care Rural Hospital by Tanvi Ramakant Sambhus, Vijaykumar B. Powar, Mangala Nagare, Sarangi Wankhade, Smita Bhide

“…Deliberation on the various methods of optimizing blood component usage and formulation of a management plan according to the trends and future forecasts is warranted. …”
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