Propionyl Carnitine Metabolic Profile: Optimizing the Newborn Screening Strategy Through Customized Cut-Offs by Maria Lucia Tommolini, Maria Concetta Cufaro, Silvia Valentinuzzi, Ilaria Cicalini, Mirco Zucchelli, Alberto Frisco, Simonetta Simonetti, Michela Perrone Donnorso, Sara Moccia, Ines Bucci, Maurizio Aricò, Vincenzo De Laurenzi, Luca Federici, Damiana Pieragostino, Claudia Rossi

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A hybrid renewable energy system for Hassi Messaoud region of Algeria: Modeling and optimal sizing by Yacine Bourek, El Mouatez Billah Messini, Chouaib Ammari, Mohamed Guenoune, Boulerbah Chabira, Bipul Krishna Saha

“…A hybrid system consisting of photovoltaic (PV) panels, wind turbines (WTs), fuel cells (FCs), and diesel generators (DGs) was modeled and optimized using a genetic algorithm (GA). The optimization process aims to minimize the annual cost of the system while ensuring high reliability, as measured by the loss of power supply probability, and maximizing the use of renewable energy. …”
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Sturge-Weber Syndrome: A comprehensive review of clinical features, optimized diagnosis and management strategies by Katarzyna Naja, Alicja Kapciak, Julia Górny, Adrianna Świerzyńska, Artur Hawajski, Natalia Jankowska, Oliwia Kamieniecka, Jakub Zwardoń, Weronika Mazur, Natalia Pawelec

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Optimizing equine standing sedation: continuous infusion of detomidine and butorphanol enhances stability but prolongs ataxia by Julia de Assis Arantes, Isabela Peixoto Rabelo, Lucas Bermudes, Milena Domingues Lacerenza, Rubens Peres Mendes, Rodrigo Romero Corrêa, Diego Iwao Yamada, Carlos Augusto de Araújo Valadão, Renata Gebara Sampaio Dória

“…Future studies should explore alternative drug combinations to optimize sedation quality while minimizing ataxia and cardiorespiratory effects.…”
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Optimizing Effects of Organic Farming and Moderately Low Nitrogen Levels on Soil Carbon and Nitrogen Pools by Guanghua Wang, Yu Yang, Yuqi Chen, Shilong Yu, Xiaomin Huang, Min Jiang, Zujian Zhang, Lifen Huang

“…Reasonable nitrogen fertilizer management and cultivation methods can enhance the nitrogen supply and carbon sequestration capabilities of soil, which is beneficial for meeting the growth requirements of crops and alleviating environmental issues. …”
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Delay margin analysis of FOTID controller for RES based EV system using MMGPE optimization by Adhit Roy, Susanta Dutta, Soumen Biswas, Anagha Bhattacharya, Sajjan Kumar, Soham Dutta, Provas Kumar Roy

“…Since the behaviour of solar and wind generation changes quickly with the environment and causes significant synchronizing imbalances between various units with system delays in large electrical grids, users face numerous challenges while shifting from conventional energy to renewable energy. …”
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Patterns of drug-related problems and the services provided to optimize drug therapy in the community pharmacy setting by Anan S. Jarab, Walid Al-Qerem, Karem H. Alzoubi, Mohammad Tharf, Shrouq Abu Heshmeh, Ahmad Al-Azayzih, Tareq L. Mukattash, Amal Akour, Yazid N Al Hamarneh

“…Objectives: To assess community pharmacists’ knowledge and practice regarding DRP-reduction services, as well as the barriers and factors associated with decreased provision of these services. Methods: This cross-sectional study utilized a validated questionnaire to assess pharmacists’ knowledge, practice, and barriers to the provision of DRP-reduction services in the community pharmacy setting. …”
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Solving 0-1 Knapsack and Bin Packing Problem Using Logical Social Group Optimization by Rhiddhi Prasad Das, Junali Jasmine Jena, Suresh Chandra Satapathy, Naeem M. S. Hannoon

“…In multiple knapsack problems, LSGO variants reach a profit of 1925 units, exceeding Particle Swarm Optimization (PSO) (1850 units). For bin packing problems, the binary splitting strategy optimally minimizes bin usage, achieving 5 bins on the P04 dataset, while maintaining solution quality. …”
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Optimizing Timing and Preparation for Allogeneic Hematopoietic Stem Cell Transplantation in Higher-Risk Myelodysplastic Syndromes by Geng L, Chen E, Ji Y, Liu H, Sun Z

“…Early HSCT emerged as the only significant factor influencing both OS (Hazard Ratio [HR] 2.84, p = 0.01) and TRM (HR 3.21, p = 0.01). While no significant differences were noted between sibling HSCT and unrelated cord blood transplantation (UCBT) for OS and TRM, UCBT demonstrated a lower incidence of chronic graft-versus-host disease (cGVHD) (19.0% vs 52.9%, p = 0.003).Discussion: Our findings suggest early allo-HSCT may optimize outcomes in higher-risk MDS. …”
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Study on the Response of Cotton Leaf Color to Plant Water Content Changes and Optimal Irrigation Thresholds by Binbin Mao, Lulu Wang, Junhui Cheng, Bing Chen, Jiandong Wang, Kai Zhang, Xiaowei Liu

“…Results demonstrated that the following: (1) plant water content initially declined during the day and subsequently showed slight recovery, indicating cotton’s particular susceptibility to water stress between 2:30 p.m. and 7:00 p.m.; (2) plant water content continuously decreased across five measurement periods following irrigation during the bud, flowering, and boll development stages, with R and G color values of the five functional leaves showing declining trends between 2:30 p.m. and 7:00 p.m., while B color values exhibited no consistent pattern; (3) correlation analysis revealed significant positive correlations between plant water content and R and G color values of the five functional leaves during the 2:30 p.m. to 5:00 p.m. period, with highly significant correlations observed for the third and fourth leaves from the apex; (4) univariate and bivariate linear regression models were successfully established between cotton water content and R and G color values of the third and fourth leaves from the top; and (5) under 72% plant water content conditions, cotton achieved the highest yield and Irrigation Water Use Efficiency, indicating that 72% represents the optimal irrigation threshold. …”
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Advanced Optimization of Flowshop Scheduling with Maintenance, Learning and Deteriorating Effects Leveraging Surrogate Modeling Approaches by Nesrine Touafek, Fatima Benbouzid-Si Tayeb, Asma Ladj, Riyadh Baghdadi

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Optimized fertilization strategies enhanced integrated benefits in nutrient management for open-field cabbage production by Mengjiao Liu, Xiya Wang, Binggeng Yang, Dali Song, Xinpeng Xu, Wencheng Ding, Ping He, Wei Zhou

“…These results highlight the multiple mechanisms of optimized fertilization methods in controlling yield and quality of cabbage. …”
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A Randomized Controlled Trial for the Optimal Implementation of Psoriasis Treatment by Integrating Chinese and Western Medicine by Yu Y, Sun X, Hu R, Xia P, Wei Y, Yang W, Huang N, Ding Y, Guo S, Yang C, Weng H, Zhang Y, Ding X, Huang Q, Zhou X, Li X, Li B

“…Currently, the prevalent guideline-recommended regimen is based on psoriasis severity; however, no corresponding studies have been conducted on the hierarchical selection of integrated Chinese and Western medicine treatments.Objective: To explore the optimal implementation of psoriasis treatment by integrating Chinese and Western medicine.Methods: We conducted a 16-week multicenter single-blind randomized controlled trial in China between December 2019 and July 2022. …”
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Optimized Yolov5s-Im for real-time apple flower detection in drone-based pollination by Shahram Hamza Manzoor, Zhao Zhang, Hongwen Li, Qu Zhang, Kuifan Chen, C. Igathinathane, Tianzhong Li, Wei Li, Muhammad Naveed Tahir, Nabil Mustafa, Mustafa Mhamed

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Effects of N management optimization practices on rice productivity and N loss: a meta-analysis by Yan Liu, Yan Liu, Yan Liu, Yan Liu, Yan Liu, Yan Liu, Zhaopeng Fu, Zhaopeng Fu, Zhaopeng Fu, Zhaopeng Fu, Zhaopeng Fu, Zhaopeng Fu, Weikang Wang, Weikang Wang, Weikang Wang, Weikang Wang, Weikang Wang, Weikang Wang, Jiayi Zhang, Jiayi Zhang, Jiayi Zhang, Jiayi Zhang, Jiayi Zhang, Jiayi Zhang, Qiang Cao, Qiang Cao, Qiang Cao, Qiang Cao, Qiang Cao, Qiang Cao, Yongchao Tian, Yongchao Tian, Yongchao Tian, Yongchao Tian, Yongchao Tian, Yongchao Tian, Yan Zhu, Yan Zhu, Yan Zhu, Yan Zhu, Yan Zhu, Yan Zhu, Weixing Cao, Weixing Cao, Weixing Cao, Weixing Cao, Weixing Cao, Weixing Cao, Xiaojun Liu, Xiaojun Liu, Xiaojun Liu, Xiaojun Liu, Xiaojun Liu, Xiaojun Liu, Xiaojun Liu

“…While current research has proposed various methods to minimize N losses, it often overlooks the need for integrated strategies that address both N losses and crop productivity. …”
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Multi-method evaluation of volatile flavor compounds in five kiwifruit varieties by ZENG Shuo, GUO Xinyu, NIU Dongsheng, LI Feng

“…In contrast, the W5C, W3C, and W2S sensors of Hongyang and Xuxiang kiwifruits showed strong responses, while the W1W sensor had relatively low response intensity across all varieties. …”
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A sequential-generation-based intelligent method for layout of pipeline supports by Jingjing Wu, Qichang He

“…Subsequently, a knowledge-driven variable-step-size sampling method introduces to optimize efficiency without compromising effectiveness. …”
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A modification design method for the angular misalignment of the spline drum shaping by YUAN Xichuan, LIU Qi, TANG Jinyuan, LI Yuan, SU Hui

“…Finite element simulation and test verification were subsequently conducted to validate the accuracy and effectiveness of this method.ResultsThe analytical results demonstrate that regarding computational efficiency, the proposed method reduces finite element simulations from 6-10 iterations required by traditional trial-and-error approaches to a single simulation for determining optimal modification, achieving over 80% efficiency improvement; in performance enhancement, the optimized modification demonstrates 30.22% reduction in contact stress and 50% decrease in maximum tooth wear volume under misalignment conditions, effectively eliminating edge contact while significantly extending service life.…”
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Evaluation method of shale reservoir fracability based on double sweet spots by SHI Can, LIN Botao, XIE Bobo, PAN Yuting, ZHANG Jiahao

“…There is an urgent need to clarify the connection between sweet spots and fracability while establishing a standardized evaluation method. …”
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Road-Adaptive Precise Path Tracking Based on Reinforcement Learning Method by Bingheng Han, Jinhong Sun

“…This paper proposes a speed-adaptive autonomous driving path-tracking framework based on the soft actor–critic (SAC) and pure pursuit (PP) methods, named the SACPP controller. The framework first analyzes the obstacles around the vehicle and plans an obstacle-free reference path with the minimum curvature using the hybrid A* algorithm. …”
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