Perceived effects of accreditation on education quality and health-related job outcomes: scales validation and correlates in Lebanon by Deema Rahme, Daniele Saade, Hala Sacre, Chadia Haddad, Samah Tawil, Samar Merhi, Randa Aoun, Aline Hajj, Fouad Sakr, Jihan Safwan, Marwan Akel, Rony M. Zeenny, Pascale Salameh

“…Multivariate analysis of covariance (MANCOVA) adjusted for sociodemographic and university-related factors, while multiple regression explored predictors of time to employment for graduates. …”
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Dihydroartemisinin-sodium taurocholate-PLGA nanoparticles: a novel therapeutic approach against cystic echinococcosis by Aierpati Moheteer, Aierpati Moheteer, Jiang Zhu, Jiang Zhu, Dongming Pang, Dongming Pang, Xue Rao, Xue Rao, Nijiati Aini, Nijiati Aini, Kalibixiati Aimulajiang, Zhenping Zhang, Zhenping Zhang, Saifuding Abula, Saifuding Abula, Adelijiang Wusiman, Adelijiang Wusiman

“…To overcome these limitations and enhance hepatic targeting, the DHA was encapsulated in poly (lactic-co-glycolic acid) (PLGA) nanoparticles, and using sodium taurocholate (STC) as the surface modifier, a novel composite nanoparticle designated as DHA-STC-PLGA nanoparticles (DSP nanoparticles).MethodsThe formulation was optimized using response surface methodology, and its targeting efficiency was confirmed through in-vivo fluorescence imaging. …”
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Gender and sex differences in the outcomes of modern coronary surgery: the main results of the Coronary Revascularization Outcomes Within Necessary Sex And Gender Aspects (CROWN-SA... by S. Kh. Lilothia, R. N. Komarov, V. B. Arutyunyan, V. A. Belov

“…Predictor of long-term MACCE and death for women was use of composite grafts, while for men — ejection fraction (EF) £40%, age >70 years, and off-pump CABG. …”
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Effects of taurine on growth performance, body composition and physiological responses of western white shrimp, Litopenaeus vannamei broodstock by Vahid Morshedi, Mahmoud Nafisi Bahabadi, Mansour Torfi Mozanzadeh, Amin Oujifard, Naser Agh, Khalegh Maneii, Ahmad Qasemi, Nehzat Bakhshi, Hadi Ebrahimi, Rezvan Tamadoni, Shirin Hamedi, Reza Bagherpour, Fatemeh Solimani

“…The obtained results showed that hyaline cells in the haemolymph of T10 upraised, while semi-granular rate (%) decreased compared to the control group (p<0.05). …”
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Frequency and Prognostic Value of Acute Periprocedural Myocardial Injury in Elective Percutaneous Coronary Interventions by E. O. Nalesnik, A. N. Repin

“…PMI was diagnosed with an increase in the level of creatine phosphokinase MB fraction (CK-MB) or or cardiac troponin I (cTn I) &gt;1×99 percentile URL (Upper Reference Limit), while the level of increase in biomarkers &gt;1, 2, 3, 4 or &gt;5×99 percentile URL was recorded. …”
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Brain tumor segmentation using deep learning: high performance with minimized MRI data by Jacky Huang, Banu Yagmurlu, Powell Molleti, Richard Lee, Abigail VanderPloeg, Humaira Noor, Rohan Bareja, Yiheng Li, Michael Iv, Haruka Itakura

“…However, this data-intensive approach is time-consuming. We aimed to optimize the process by using a deep learning (DL) based model while minimizing the number of MRI sequences required to segment gliomas.MethodsWe trained a 3D U-Net DL model using the annotated 2018 MICCAI BraTS dataset (training dataset, n = 285), focusing on sub-segmenting enhancing tumor (ET) and tumor core (TC). …”
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Prediction of sinus rhythm maintenance after radiofrequency ablation in patients with atrial fibrillation using speckle tracking echocardiography and dynamics of left atrial struct... by T. I. Musin, Z. A. Bagmanova, D. A. Gareev, V. G. Rudenko, N. Sh. Zagidullin

“…To evaluate the dynamics of left atrial volume (LAV), strain (S) during the reservoir phase and strain rate (SR) in patients with paroxysmal and persistent atrial fibrillation (AF), scheduled for catheter radiofrequency ablation (RFA), as well as to compare the predictive value of S and SR as a marker of maintaining sinus rhythm.Material and methods. A total of 19 patients (men, 11; women, 8) aged 62±10,7 years with AF were included in the study, 13 (67%) of whom had persistent AF, while 6 patients (33%) had paroxysmal AF Two-dimensional and speckle tracking N. …”
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Immunohistochemical analysis of PD-L1, CD4, CD8, CD20, and PU.1 expression in a dedifferentiated chondrosarcoma: the clinical and prognostic value by Olga V. Kovaleva, Irena V. Boulytcheva, Dmitrii V. Rogozhin, Alexei N. Gratchev, Polina L. Prishchep, Nikolay E. Kushlinskii

“…Median survival of the PD-L1 non-expressing patients was 68.6 months, while of those with the expression 7.7 months (p = 0.096). …”
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Impact of tumor diameter on post-radiofrequency ablation survival and local progression risk in patients with colorectal cancer lung metastasis by YING Leilei, LI Kening, CHEN Chao, WANG Ying, HUANG Haozhe, WANG Biao, LI Wentao, HE Xinhong

“…A tumor diameter of 3 cm can serve as a critical threshold for selecting RFA indications, and combining preoperative CEA levels can optimize patient stratification.…”
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Development and validation of a machine learning-based risk prediction model for stroke-associated pneumonia in older adult hemorrhagic stroke by Yi Cao, Yi Cao, Haipeng Deng, Shaoyun Liu, Xi Zeng, Yangyang Gou, Weiting Zhang, Yixinyuan Li, Hua Yang, Min Peng

“…Model performance was compared using Delong's test or Bootstrap test, while sensitivity, specificity, accuracy, precision, recall, and F1-score evaluated predictive efficacy. …”
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Inflammatory and Nutritional Biomarker in Different Subtypes of Early Stage Diffuse Large B-Cell Lymphoma: Towards a Diagnostic Model by Oehadian A, Gunadi SV, Mersiana L, Susandi E, Wijaya I, Martha JW, Supriyadi R, Prihatni D

“…Accurate subtyping is crucial due to differences in prognosis and treatment response. While gene expression profiling is the gold standard, it is often unavailable in low-resource settings. …”
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CPAP modulation of sleep microstructure (N2-SSD and REM-AHI) as predictors of neurological recovery in ischemic stroke patients with moderate-to-severe OSA by Tianyu Jing, Tianyu Jing, Tianyu Jing, Liwen Xu, Liwen Xu, Shutong Sun, Wenyi Yu, Wenyi Yu, Yixi Zheng, Yixi Zheng, Gang Xu, Xinhao Shen, Tieyu Tang, Cheng Chu, Cheng Chu

“…The findings are expected to optimize treatment strategies and improve overall patient outcomes.MethodsA total of 141 patients with IS combined with moderate-to-severe OSA admitted to the Affiliated Hospital of Yangzhou University from October 2022 to August 2024 were enrolled. …”
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Evaluation of the hypercholesterolemia care cascade and compliance with NCEP-ATP III guidelines in Iran based on the WHO STEPS survey by Shirin Djalalinia, Sepehr Khosravi, Moein Yoosefi, Sarvenaz Salahi, Zahra Shokri Varniab, Ali Golestani, Nazila Rezaei, Ameneh Kazemi, Arezou Dilmaghani-Marand, Negar Rezaei, Erfan Ghasemi, Naser Ahmadi, Mohammad-Mahdi Rashidi, Yosef Farzi, Kamyar Rezaee, Maryam Nasserinejad, Sina Azadnajafabad, Elham Abdolhamidi, Rosa Haghshenas, Arefeh Alipour Derouei, Azadeh Momen Nia Rankohi, Farshad Farzadfar

“…Of those receiving treatment, 52.85% (females) and 53.93% (males) achieved optimal LDL, while 76.98% (females) and 81.06% (males) attained total cholesterol < 200 mg/dL. …”
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Trends in inpatient antibiotic use in Indonesia and the Philippines during the COVID-19 pandemic by Amara Z. Fazal, Olivia L. McGovern, Garrett W. Mahon, Fernanda C. Lessa, Maria Tarcela Gler, Jemelyn Garcia, Mark John Festin, Kuntaman Kuntaman, Ida Parwati, Cherry Siregar, Jay Christian D. Muere, Gina De Guzman Betito, Maya Montemayor, Arleen De Leon, Emmeline Borillo, Mark Ramon Victor Llanes, Regina Berba, Musofa Rusli, Mariyatul Qibtiyah, Bambang Pujo Semedi, Rosantia Sarassari, Leonardus Widyatmoko, Basti Andriyoko, Adhi Kristianto Sugianli MD, Dewi Kartika Turbawaty, Ivo Dhanitri Ranita, Franciscus Ginting, Rahmadania Marita Joesoef, Made Ananda Krisna, Twisha S. Patel

“…We assessed changes in AU during the COVID-19 pandemic in Indonesia and the Philippines. Methods: We evaluated hospital-wide AU over 36 months in six hospitals, 3 in Indonesia and 3 in the Philippines. …”
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What Changes are Mandatory in Breast Surgery Training? An International Survey and Recommendations of the French Academy of Surgery and the Senologic International Society by Tolga Ozmen, Caroline Bouche, Megane Buttignol, Bolivar Arboleda-Osorio, Mauricio Magalhaes Costa, Henry Coudane, Darius Dian, Xishan Hao, Shigeru Imoto, Olivier Jardé, Hubert Johanet, Esther Meka, Alexander Mundinger, Ruben Orda, Vahit Ozmen, Tadeusz Pienkowski, Schlomo Schneebaum, Charlotte Vaysse, Susie Brousse, Atilla Soran, Carole Mathelin

“…Most respondents (66%) had over 15 years of experience, and 75% were male. While 50% reported that breast surgery fellowships were not mandatory, countries with requirements often stipulated a one or two-year experience and a minimum cases number. …”
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VENETOCLAX-BASED VERSUS 7+3 INDUCTION THERAPY IN FIT YOUNGER ADULTS WITH NEWLY DIAGNOSED NON-CBF AML by Dmitrii Zhogolev, Nikita Pastukhov, Bella Aybova, Anna Smirnova, Ivan Moiseev, Sergey Bondarenko, Alexander Kulagin

“…Survival analysis was conducted using the Kaplan-Meier method and log-rank test. Cumulative incidences of relapse and NRM were assessed using competing risk models with Gray’s test. …”
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Pembrolizumab-axitinib versus nivolumab-cabozantinib as first-line therapy in patients with metastatic renal cell carcinoma: a retrospective real-world comparison (ARON-1) by Matteo Santoni, Giandomenico Roviello, Enrique Grande, Ugo De Giorgi, Ondrej Fiala, Emmanuel Seront, Javier Molina-Cerrillo, Renate Pichler, Zin W. Myint, Jakub Kucharz, Ravindran Kanesvaran, Thomas Büttner, Martin Pichler, Umberto Basso, Jindrich Kopecky, Maria T. Bourlon, Linda Cerbone, Tomas Buchler, Alvaro Pinto, Alfonso Gómez de Liaño, Caterina Gianni, Anca Zgura, Pasquale Rescigno, Jawaher Ansari, Orazio Caffo, Zsófia Küronya, Maria Giuseppa Vitale, Dipen Bhuva, Martina Catalano, Nuno Vau, Ray Manneh Kopp, Sebastiano Buti, Aristotelis Bamias, Camillo Porta, Kaisa Sunela, Francesco Massari

“…Abstract Background The optimal first-line therapy for metastatic renal cell carcinoma (mRCC) remains uncertain, despite recent advancements in immune-based combinations. …”
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Efficacy test of a Mycoplasma hyorhinis mRNA-LNP vaccine candidate by Eszter Zsófia Nagy, Levente Szeredi, Hiromi Muramatsu, Noémi Nagy, Dénes Grózner, Zsuzsa Kreizinger, Kinga M. Sulyok, Bandana Pangabam, Lilla Tóth, Rachel H.J. Jun, Dorottya Földi, Enikő Wehmann, Miklós Tenk, Norbert Pardi, Miklós Gyuranecz

“…Therefore, the present study aimed to develop a M. hyorhinis mRNA-LNP vaccine candidate. Materials and methods: The selected antigens were highly conserved proteins involved in bacterial adhesion. …”
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Enhancing fermentation quality and fiber decomposition of Phragmites australis silage by introducing Bacillus subtilis and lactic acid bacteria consortia by Yong Liu, Songbai Zhang, Junrui Liao, Nazir Ahmad Khan, Shaoxun Tang, Chuanshe Zhou, Zhiliang Tan, Asmaa Elnagar, Ibrahim F. Rehan, Ibrahim F. Rehan, Ibrahim F. Rehan, František Zigo, Abdelfattah Z. M. Salem, Abdelfattah Z. M. Salem

“…Acetic and butyric acid concentrations were significantly reduced (p &lt; 0.05), while neutral detergent fiber (NDF) decreased by 5.9% compared to the Control. …”
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Expression characteristics and functional identification of PpD2 gene in peach (Prunus persica) by XIE Hefang, ZHANG Yajia, ZHANG Junjie, LIAN Xiaodong, ZHANG Haipeng, CHENG Jun, WANG Wei, HOU Nan, WANG Lei, ZHENG Xianbo, FENG Jiancan, WANG Xiaobei, TAN Bin

“…These challenges highlight the emergent need to optimize tree architecture and develop labor-saving cultivars to address the developmental bottlenecks in the peach industry. …”
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