Conservation of Verbascum sinaiticum Benth using innovative tissue culture technique and DNA barcoding by Mohamed Abdel-Shakur Ali, Nora Rabee Gowda, Mai A. Allam, Sayed A. Fayed

“…We have devised flexible methods for large-scale micropropagation that offer a sustainable and quick production strategy, even in the face of resource constraints. …”
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Development and external validation of machine learning models for the early prediction of malnutrition in critically ill patients: a prospective observational study by Yi Liu, Yehua Xu, Lixia Guo, Zhongbin Chen, Xueqin Xia, Feng Chen, Li Tang, Hua Jiang, Caixia Xie

“…Hyperparameters were optimized via 5-fold cross-validation on the training set, eliminating the need for a separate validation set while ensuring internal validation. …”
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A nomogram for predicting early bacterial infection after liver transplantation: a retrospective study by Jie Yu, Jie Yu, Jichang Jiang, Jichang Jiang, Caili Fan, Caili Fan, Jinlong Huo, Jinlong Huo, Tingting Luo, Tingting Luo, Lijin Zhao, Lijin Zhao

“…It can effectively identify the high-risk group for bacterial infection in the early postoperative period after liver transplantation, while simultaneously helping the transplant team dynamically monitor the key indicators and optimize perioperative management.…”
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Cervical cerclage for prevention of preterm birth and adverse perinatal outcome in twin pregnancies with short cervical length or cervical dilatation: A systematic review and meta-... by Francesco D'Antonio, Nashwa Eltaweel, Smriti Prasad, Maria Elena Flacco, Lamberto Manzoli, Asma Khalil

“…<h4>Background</h4>The optimal approach to prevent preterm birth (PTB) in twins has not been fully established yet. …”
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An assessment of the level of knowledge about diabetes mellitus among diabetic patients in a primary healthcare setting by Lushendran M. Moodley, Viren Rambiritch

“…Section A investigated basic patient history (demographics and disease state), while section B was a basic knowledge test on diabetes mellitus. …”
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Impact of Obesity on the Long-Term Outcomes of Advanced Therapies in IBD: A Real-World Study in Taiwan by Hsu WC, Lin SH, Kuo CJ, Chiu HY, Chen CM, Su MY, Chiu CT, Chang CW, Huang TY, Pan YB, Le PH

“…Future studies should explore optimal therapies for obese IBD patients.Keywords: inflammatory bowel disease, advanced therapies, drug persistence, overweight, obesity…”
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Cone-beam CT measurement of root canal diameter and taper for mandibular first molar by LI Wenmiao, XING Li, PAN Yingyu, HUANG Ying, YANG Guofang, LIU Deda

“…Objective·To analyze the root canal diameter and taper of mandibular first molars using cone-beam CT (CBCT), investigate age-related changes in these parameters, and propose optimized clinical protocols for root canal preparation.Methods·From October 2022 to October 2023, CBCT images of 240 healthy mandibular first molars (120 three-canal type cases and 120 four-canal type cases) were collected from patients aged 20‒59 years at the Stomatology Center, Haikou Affiliated Hospital of Central South University Xiangya School of Medicine. …”
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Effectiveness of Telemedicine Interventions on Motor and Nonmotor Outcomes in Parkinson Disease: Systematic Review and Network Meta-Analysis by Jiejie Dou, Junyu Wang, Xianqi Gao, Guotuan Wang, Ying Bai, Yixin Liang, Kunyi Yang, Yong Yang, Lin Zhang

“…ConclusionsTelemedicine is effective for improving motor and nonmotor outcomes in PD. e-Exercise is optimal for motor function and physical performance, while e-Cognitive is most effective for psychological and cognitive challenges. …”
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Novel triple-target panels utilizing methylation-sensitive restriction enzyme-based quantitative PCR for detecting advanced cervical precancers and cancers among high-risk HPV-posi... by Shimin Chen, Hongshuang Dai, Shangying Hu, Tangjie Gao, Ming Chen, Xinghua Zhou, Lizhong Dai, Xuelian Zhao, Fanghui Zhao

“…Abstract Background Optimal triage option for high-risk HPV-positive (hrHPV) women remains uncertain. …”
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Molecular subtype of recurrent implantation failure reveals distinct endometrial etiology of female infertility by Jing Yang, Lingtao Yang, Ying Zhou, Fengyang Cao, Hongkun Fang, Huan Ma, Jun Ren, Chunyu Huang, Lianghui Diao, Qiyuan Li, Qionghua Chen

“…Abstract Background Recurrent implantation failure (RIF) remains a significant barrier in assisted reproductive technology (ART), where multiple transfers of high-quality embryos fail to achieve pregnancy. While embryo-related factors have been extensively investigated, the contribution of endometrial dysfunction to RIF remains poorly characterized. …”
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National and subnational burden of brain and central nervous system cancers in China and global from 1990 to 2021: results from the global burden of disease study 2021 by Shifan Tu, Xiaolu Huang, Xiaoxuan Fan, Yi Zhang, Lan Huang, Kai Li, Xinyue Wang, Yunpeng Gao, Xiaoping Zhao, Zhaoqun Feng

“…These updated findings provide critical insights for optimizing resource allocation and informing tailored interventions. …”
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New mouse model based on adenocarcinoma 4T1 cells expressing HPV16 E6 and E7 applied to assess the efficacy of therapeutic and prophylactic E6/E7-based HPV16 vaccines by Juris Jansons, Daria Avdoshina, Alesja Dudorova, Elena Royo Rubio, Liba Sokolovska, Dmitry Perminov, Ilze Lindenberga, Hannes Nicolai, Svetlana Gebrila, Sona Chowdhury, Dace Skrastina, Jurijs Nazarovs, Joel M. Palefsky, Maria Isaguliants

“…E7 DNA was nonimmunogenic, while unstimulated T-cells produced TNF-α. In prophylactic settings, DNA-immunization with E6 and E7 suppressed formation of B2/H6 tumors. …”
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Grass hay mixed-in creep feed or separately-fed differentially affects digestive development in pre- and post-weaning piglets by Renjie Yao, Tetske G. Hulshof, Hubèrt M. J. van Hees, An Cools, Mattijs Merckx, Dominiek Maes, Geert P. J. Janssens

“…Following weaning, GH nursery group had a reduced average daily gain (226 vs. 183 g, P < 0.001) during d 0–14, while this group showed compensatory growth afterwards (P = 0.056). …”
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Effect of triple therapy on mortality and cardiovascular risk in patients with moderate to severe COPD: a meta-analysis of randomized controlled trials by Yubing Li, Jun Li, Hongxia Yang, Yong Zhang

“…Abstract Background Chronic obstructive pulmonary disease (COPD), the third leading cause of global mortality, remains a significant challenge in long-term management. While dual bronchodilators (LAMA/LABA) and inhaled corticosteroid combination therapies (ICS/LABA) alleviate symptoms, patients continue to face elevated risks of all-cause mortality and cardiovascular events. …”
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Risk factors and predictive thresholds for postoperative pleural effusion in children with neuroblastoma: a retrospective cohort study by Jing Hu, Ping Chu, Jun Feng, Xinran He, Lijing Li, Yi Ren, Zhe Su, Wei Yang, Jianmin Zhang, Fang Wang

“…Perioperative inflammation modulation might represent a potential target for risk reduction, while maintaining adequate albumin levels and optimizing preoperative nutrition could be considered as supportive strategies. …”
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Prevalence of CYP2C19 Variants in Patients with Cardiovascular Disease from the Yunnan-Guizhou Plateau in Southwestern China by Li XP, Wang JL, Lei SX, Chen BY, Ma X, He F, Yue CF, Liu HX, Hu JP, Xiong Q, Ji T, Zhang ZF, Sun Y, Li HW

“…Here, differences in CYP2C19 alleles, genotypes, and phenotypes in patients with cardiovascular disease from the Yunnan-Guizhou Plateau were systematically surveyed to provide a reference for appropriate treatment approaches.Methods: The CYP2C19&amp;ast;2, &amp;ast;3, and &amp;ast;17 variants were determined by RT-qPCR in 1934 patients with cardiovascular disease from 10 different areas of the Yunnan-Guizhou Plateau. …”
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The contribution of personalized video feedback to robotic partial nephrectomy training in realistic 3D tumor kidney models: design, production and implementation by Ahmet Furkan Sarıkaya, Kayhan Tarım, Ersin Köseoğlu, Arif Özkan, İbrahim Can Aykanat, Baris Esen, Umut Can Karaarslan, Mustafa Müdüroğlu, Şevval Kanlı, Murat Can Kiremit, Yakup Kordan, Mevlana Derya Balbay, Tarık Esen, Serdar Aydın, Serdar Aydın, Abdullah Erdem Canda, Abdullah Erdem Canda

“…This study investigates the impact of 3D-printed renal models and video-based feedback on skill acquisition in robotic partial nephrectomy training.MethodsForty urology residents without prior robotic surgery experience participated in this study. …”
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Rapid Initiation of Antiretroviral Therapy Suppresses T Cell Pathological Proliferation and Improves Immune Recovery in People Living with HIV by Ji J, Guo C, Li Z, Cai M, Wang R, Chen X, Zhang Y, Wu H, Zhang T, Zhang Y

“…Additionally, CD8⁺ T cells in the rapid ART group exhibited an increased presence of TN cells while showing a decreased proportion of PD-1/HLA-DR/CD38 high-expressing cells. …”
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Comparative effectiveness and safety of tenofovir alafenamide versus tenofovir disoproxil fumarate in patients with HBV-associated decompensated cirrhosis: insights from a retrospe... by Lu Chen, Hui-Fang Zhang, Yi-Jing Cai, Lei Zhang, Chao Cai, Ming-Qin Lu, Yue-Ying Zhu

“…Given the severity of decompensated cirrhosis, selecting the most appropriate first-line antiviral medication is crucial for optimizing treatment outcomes and providing the best possible disease control. …”
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How does social support influence autonomous physical learning in adolescents? Evidence from a chain mediation and latent profile analysis. by Jiamin Zhu, Ziyou Huang, Xiaoping Meng, Zhiyong Zhang, Xiaotong Yuan

“…The goal is to provide insights into how social support can enhance adolescents' engagement in physical activities and inform intervention strategies.<h4>Methods</h4>A total of 2,359 junior high school students (1,208 males and 1,151 females; mean age = 13.21 ± 0.96 years) from three public schools in Shandong Province were surveyed between October and December 2024. …”
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