Phase transformation and flow simulation of weld pools at the crack tips of elbows under pulsed current by Si ZHANG, Mingjiang ZHOU, Yuheng LIANG, Biwei FU

“…Consequently, a pulse interval greater than 0.008 seconds was identified as optimal to prevent adverse effects on the weld pool area during subsequent pulses, thereby enhancing repair performance. …”
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Distinct Roles of HHLA2 and PD-L1 in the Immune Cell and Prognosis of Hepatocellular Carcinoma by Wang CH, Chen SL, Yang X, Wu T, Liu LL, Yun JP

“…Hematoxylin and eosin (H&E) staining was utilized to quantify TILs (percentage/area), while IHC was used to measure the densities of CD3+, CD4+, and CD8+ TILs (cells/mm²).Results: HHLA2 and PD-L1 exhibited similar positivity rates. …”
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Evaluation of Self-Regulating Doped Ferrite Nanoparticles with Glucose, Chitosan, and Poly-Ethylene Glycol Coatings for Hyperthermia and Dual Imaging by Negri A, Conti A, Milan E, Forlin E, Gherlinzoni F, Morana G, Gottardi M, Matteazzi P, Speghini A, Bongers A, Marzola P

“…GM55, in particular, offers superior MFH efficacy and cellular uptake, while CM55 and PM55 may present unique advantages for alternative biomedical applications. …”
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Improving AI-Based Clinical Decision Support Systems and Their Integration Into Care From the Perspective of Experts: Interview Study Among Different Stakeholders by Godwin Denk Giebel, Pascal Raszke, Hartmuth Nowak, Lars Palmowski, Michael Adamzik, Philipp Heinz, Marianne Tokic, Nina Timmesfeld, Frank Martin Brunkhorst, Jürgen Wasem, Nikola Blase

“… BackgroundArtificial intelligence (AI)–based systems are receiving increasing attention in the health care sector. While the use of AI is well advanced in some medical applications, such as image recognition, it is still in its infancy in others, such as clinical decision support systems (CDSS). …”
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Prognostic value of albumin-corrected anion gap in critically ill patients with sepsis-associated liver injury: a retrospective study by Jianjun Wang, Yonghai Peng, Zhaohui Hu, Xi Chen, Sirui Chen, Pei Yang, Xintao Zeng, Decai Wang

“…We explored the association between ACAG and patient prognosis in individuals diagnosed with SALI. Methods Data from patients with SALI admitted to the intensive care unit (ICU) between 2008 and 2022 were retrospectively analyzed. …”
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A real-world disproportionality analysis of FDA adverse event reporting system (FAERS) events for lecanemab by Linlin Yan, Linhai Zhang, Zucai Xu, Zhong Luo

“…A biweekly 10 mg/kg was identified as the optimal therapeutic dosage. ARIA emerged as frequent treatment-related AEs, with APOEɛ4 carriers demonstrating heightened susceptibility. …”
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SARS-CoV-2 Variant-Specific Antibodies in Vaccinated Inflammatory Bowel Disease Patients by Eva Ulla Lorentzen, Richard Vollenberg, Rieke Neddermeyer, Michael Schoefbaenker, Eike R. Hrincius, Stephan Ludwig, Phil-Robin Tepasse, Joachim Ewald Kuehn

“…Anti-TNF-treated individuals with antibody levels below the optimized CMIA threshold should be considered for early booster vaccination and/or close immunological monitoring.…”
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Geriatric Nutritional Risk Index (GNRI) and Prognostic Nutritional Index (PNI) Before Treatment as the Predictive Indicators for Bone Metastasis in Prostate Cancer Patients by Chen L, Rao H, Chen N, Li R, Chen D, Jiang H

“…The levels of GNRI and PNI in patients with bone metastasis were significantly lower than those without, while NAR, PIV, SII, and SIRI were not statistically significant. …”
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Peer2Me - impact of peer support on self-efficacy in young adult cancer survivors (YA-CS): findings from a comprehensive cohort design by Hannah Brock, Sarah Dwinger, Michael Friedrich, Annekathrin Sender, Kristina Geue, Anja Mehnert-Theuerkauf, Corinna Bergelt, Diana Richter

“…Although interest in peer mentoring was high, the intervention showed no measurable benefit in comparison with standard care. While the need for support was evident, further research is required to optimize peer interventions for this group. …”
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Integrative habitat analysis and multi-instance deep learning for predictive model of PD-1/PD-L1 immunotherapy efficacy in NSCLC patients: a dual-center retrospective study by Xiaoxiao Huang, Xiaoxin Huang, Yurun Xie, Kui Wang, Housheng Bai, Ruiling Ning, Xiqi Zhu, Deyou Huang, Guanqiao Jin

“…This dual-center study aimed to integrate habitat radiomics and multi-instance deep learning to predict durable clinical benefits from immunotherapy. Methods We retrospectively collected 590 NSCLC patients from two medical centers who received PD-1/PD-L1 inhibitor immunotherapy. …”
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Atrial fibrillation and chronic kidney disease: main clinical characteristics of patients in selected subjects of the Russian Federation by M. A. Druzhilov, T. Yu. Kuznetsova, O. Yu. Druzhilova, U. D. Arustamova, D. V. Gavrilov, A. V. Gusev

“…Patients with AF and eGFR <60 ml/min/1,73 m2 are charac­terized by greater comorbidity, a higher incidence of IS, MI and ICH compared with patients with AF and eGFR ≥60 ml/min/1,73 m2, while ACT prescription rate as of 2016-2019 in some Russian subjects was unsatisfactory. …”
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Digital Health Intervention on Awareness of Vaccination Against Influenza Among Adults With Diabetes: Pragmatic Randomized Follow-Up Study by Yifat Fundoiano-Hershcovitz, Felix Lee, Catherine Stanger, Inbar Breuer Asher, David L Horwitz, Omar Manejwala, Jan Liska, David Kerr

“…Group B showed significantly higher awareness of influenza risks compared with the control group odds ratio (OR; OR 1.35, 95% CI 1.12-1.63; P=.001), while group A did not (OR 1.10, 95% CI 0.92-1.32; P=.27). …”
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Construction of a nomogram prediction model for the pathological complete response after neoadjuvant chemotherapy in breast cancer: a study based on ultrasound and clinicopathologi... by Pingjuan Ni, Yuan Li, Yu Wang, Xiuliang Wei, Wenhui Liu, Mei Wu, Lulu Zhang, Feixue Zhang

“…ObjectiveTo explore the application value of ultrasound in evaluating the efficacy of neoadjuvant chemotherapy (NAC) for breast cancer and construct a nomogram prediction model for pathological complete response (pCR) following different cycles of NAC based on ultrasound and clinicopathological features, and further investigate the optimal prediction cycle.MethodsA total of 249 breast cancer patients who received NAC were recruited. …”
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Research on the effectiveness of health information dissemination via the “Shanghai CDC” WeChat public account by GUO Ying, WANG Xiaoxuan, XIA Wen, HUANG Xiaoyan, HU Xuanmeng, SHEN Qi, DONG Chen

“…ObjectiveTo explore the effectiveness of health information dissemination and its influencing factors using the "Shanghai CDC" WeChat public account as a case study, providing references for public health institutions to optimize the use of official new media platforms for effective publicity.MethodsA total of 1 030 headline articles published on the "Shanghai CDC" WeChat public account between 2016 and 2019 were analyzed using content analysis and non-parametric tests to examine the impact of factors such as titles and content categories.ResultsFrom 2016 to 2019, the number of WeChat public account followers increased by 280 000, with the articles accumulating over 8.8 million views. …”
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Mass drug administration coverage and its determinants for the elimination of onchocerciasis in Ulanga District, Tanzania. by Ambakisye Kuyokwa Mhiche, Dinah Gasarasi, George Kabona, Ally Hussein, Upendo John Mwingira, Ahmed Mohamed Abade

“…<h4>Conclusion</h4>MDA coverage below the WHO optimally recommended coverage has been demonstrated in the villages studied. …”
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Unveiling PANoptosis in Acute Kidney Injury: An Integrative Multi-Dimensional Approach to Identify Key Biomarkers by Wang N, Zhang L, Xu Z, Xu Q, Lu Y, Niu P, Yan L, Wang L, Cao H, Shao F

“…PANoptosis, a highly regulated and complex form of programmed inflammatory cell death, integrates the molecular mechanisms of apoptosis, pyroptosis, and necroptosis. While this process has been implicated in various inflammatory conditions, its specific role in AKI remains unclear.Methods: The role of PANoptosis in AKI was investigated using single-cell RNA sequencing (scRNA-seq) and bulk transcriptomic data. …”
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Adjusting Aspergillus niger pellet diameter, population heterogeneity, and core architecture during shake flask cultivation by K. Engelbert, C. Deffur, T. C. Cairns, F. Zhang, T. Kheirkhah, H. Winter, S. Junne, P. Neubauer, H. Briesen, V. Meyer

“…These data identified optimal culture conditions which cause minimal macromorphological variation within individual flasks and between technical replicates. …”
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Design of AgI/BiVO4 heterostructures for photocatalytic antibiotic removal and antimicrobial action by Hanh Thi Truong, Tho Truong Pham, Nhi Dinh Bui, Ha Tien Le, Thuan Chi Nguyen

“…TEM revealed quasi-spherical nanocomposite particles (100–200 nm), while FE-SEM showed bright AgI nanoparticles distributed on the BiVO _4 surface. …”
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Ameliorating Effect of Cordyceps militaris on Antibiotic Intestinal Barrier Injury in Mice by Fengli YU, Jiani WANG, Siqing LIAO, Qi ZHANG, Shenghou WANG, Ze WANG

“…Objective: To investigate the protective effects of Cordyceps militaris on antibiotic-induced intestinal damage in mice, induced by the combined administration of cefuroxime axetil and levofloxacin hydrochloride. Methods: Mice were administered high (5×), medium (3×), and low (1×) doses of cefuroxime axetil and levofloxacin hydrochloride for 14 consecutive days. …”
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Deep learning assisted analysis of biomarker changes in refractory neovascular AMD after switch to faricimab by Michael Hafner, Franziska Eckardt, Jakob Siedlecki, Benedikt Schworm, Tina R. Herold, Ben Asani, Siegfried G. Priglinger, Johannes B. Schiefelbein

“…Faricimab demonstrated significant and sustained anatomical improvements, allowing for extended treatment intervals while maintaining disease stability. Future research should focus on refining AI models to improve predictive accuracy and assessing long-term outcomes to further optimize disease management. …”
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