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7621
Does prioritization of COVID vaccine distribution to communities with the highest COVID burden reduce health inequity?
Published 2025-11-01“…We evaluated the impact of vaccine prioritization strategies on COVID-19 infections and mortality in New York City (NYC). Methods: We used a susceptible-exposed-infected-recovered COVID-19 transmission model calibrated to NYC neighborhood-level data to compare three vaccine distribution strategies: 1) uniform across neighborhoods (no prioritization); 2) prioritizing hardest-hit neighborhoods (exposure-based prioritization); and 3) prioritizing hardest-hit neighborhoods while maintaining mitigation measures in other neighborhoods (exposure-based prioritization plus mitigation). …”
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7622
ChatGPT-o1 Preview Outperforms ChatGPT-4 as a Diagnostic Support Tool for Ankle Pain Triage in Emergency Settings
Published 2025-04-01“… Introduction: ChatGPT, a general-purpose language model, is not specifically optimized for medical applications. This study aimed to assess the performance of ChatGPT-4 and o1-preview in generating differential diagnoses for common cases of ankle pain in emergency settings. …”
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7623
Implementing intranasal povidone-iodine in the orthopedic trauma surgery setting to prevent surgical site infections: a qualitative study of healthcare provider perspectives
Published 2025-02-01“…Before implementing the PVI intervention, we conducted a human factors task analysis to determine the optimal time and hospital location to perform PVI decolonization for patients receiving these orthopedic fixation procedures. …”
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7624
Comparative efficacy and safety of non-pharmacological interventions on treatment-induced xerostomia in head and neck cancer patients: a systematic review and network meta-analysis
Published 2025-07-01“…AimTo comprehensively evaluate the efficacy and safety of non-pharmacological interventions for radiotherapy-induced xerostomia in patients with head and neck cancer.MethodsA systematic literature search was conducted in PubMed, Embase, the Cochrane Library, and Web of Science for articles published up to March 1, 2025. …”
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7625
Distinct infectivity and neutralization antibody responses in the highly homologous AAV Go.1 and AAV5
Published 2025-04-01“…However, their therapeutic potential and biological properties remain underexplored.MethodsIn this study, we developed a recombinant AAV (rAAV) Go.1 by replacing the goat AAV rep gene with the standard AAV2-rep gene to improve packaging efficiency. …”
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7626
Hydrogel and scalp/skin conductivities impact dose from tumor treating fields
Published 2025-02-01“…GTV hotspots decreased by +17% in E5% at 1 S/m.ConclusionTTFields delivery can be modulated by the conductivity of hydrogel and scalp/skin at the transducer-scalp or transducer-skin interface. Optimizing this aspect of TTFields delivery may increase tumor control while minimizing toxicity at the scalp or skin.…”
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7627
Emerging Therapies in the Treatment of Prurigo Nodularis: Biological Therapy and Systematic Review of Literature
Published 2025-05-01“…Dupilumab and nemolizumab emerge as first-line therapies with favorable safety profiles, while JAK inhibitors provide rapid relief for refractory cases. …”
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7628
Time to replace the oral glucose tolerance test for cystic fibrosis related diabetes first-step screening? Establishing glycemic tools relevant to cystic fibrosis
Published 2025-12-01“…However, this is a cumbersome test with poor adherence, and emerging evidence suggests that HbA1c or serum fructosamine might be viable alternative screening tools.Research Design and Methods A multi-center study across four Canadian adult CF centers was conducted to determine the ability of HbA1c and serum fructosamine levels to predict screening OGTT results. …”
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7629
Study on Soil Nutrients and Microbial Community Diversity in Ancient Tea Plantations of China
Published 2025-06-01“…Sustained excess of AN and SOM may lead to over-proliferation of dominant microorganisms, inhibition of other functional microbial communities, and disruption of ecological balance. Therefore, optimizing nutrient input methods during fertilization is recommended.…”
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7630
Associations between exercise and university students’ depression during the COVID-19 pandemic and lockdown: the mediating role of relative deprivation and subjective exercise expe...
Published 2025-08-01“…Exercise frequency demonstrates a significant association with RD, which appears to alleviate depressive symptoms. To optimize the depression-alleviating benefits of exercise, students should engage in moderate exercise to avoid excessive fatigue while maintaining positive exercise experiences.…”
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7631
Analysis of Acupoint Selection and Combinations in Acupuncture Treatment of Trigeminal Neuralgia: A Protocol for Data Mining
Published 2025-07-01“…It severely impairs patients’ quality of life, disrupting daily activities with intense facial pain. While acupuncture has proven effective in treating it, there’s no consensus on acupoint selection. …”
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7632
Evaluating the potential of graphene oxide to promote skeletal muscle complex regeneration
Published 2025-07-01“…Additionally, the effects of exosomes derived from GO-treated C2C12 myoblasts on osteoblasts were explored.MethodsC2C12 cells were cultured with different concentrations (0.1, 0.5, 2.5, 12.5, and 62.5 μg/mL) and particle sizes (>500 and <500 nm) of GO. …”
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7633
Machine learning-based diagnostic and prognostic models for breast cancer: a new frontier on the clinical application of natural killer cell-related gene signatures in precision me...
Published 2025-05-01“…With the advent of machine learning (ML) techniques, predictive modeling based on NRGs may offer a new avenue for precision oncology.MethodsWe collected transcriptomic and clinical data from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. …”
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7634
Changes in heart rate variability induced by E-sports activities
Published 2025-04-01“…Within this context, an in-depth exploration of E-sports from an exercise science perspective not only aids in optimizing players’ training and performance but also contributes important theoretical and practical value to the advancement of exercise science. …”
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7635
Geostatistics Precision Agriculture Modeling on Moisture Root Zone Profiles in Clay Loam and Clay Soils, Using Time Domain Reflectometry Multisensors and Soil Analysis
Published 2025-07-01“…Modeling results revealed that the best-fitted semi-variogram models for the granular attributes were circular, exponential, pentaspherical, and spherical, while for hydraulic attributes were found to be exponential, circular, and spherical models. …”
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7636
Effectiveness Of The Core Activation And Rehabilitation Exercises For Knee Osteoarthritis - Program (CARE -KOA©) Among Patients Diagnosed With Knee Osteoarthritis. [version 4; peer...
Published 2025-07-01“…Muscle strength gains were significant in flexors of the unaffected knee and extensors of the affected knee (p < 0.05), while other muscle groups showed no significant change. …”
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7637
Assessing eligibility for lung cancer screening using parsimonious ensemble machine learning models: A development and validation study.
Published 2023-10-01“…<h4>Background</h4>Risk-based screening for lung cancer is currently being considered in several countries; however, the optimal approach to determine eligibility remains unclear. …”
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7638
Nurses’ Perspectives on the Sleep Quality of Hospitalized Patients in Al Ahsa, Saudi Arabia
Published 2025-02-01“…Background: Sleep quality is crucial for patient recovery and well-being, yet hospitalized patients often suffer from poor sleep due to environmental disruptions, clinical routines, and psychosocial stressors. While these challenges are well-documented, qualitative insights into nurses’ perspectives—essential frontline providers shaping the sleep environment—are scarce, especially within rapidly evolving healthcare systems like Saudi Arabia’s. …”
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7639
Three-dimensional assessment of maxillary arch changes in infants with bilateral cleft lip and palate using vacuum-formed nasoalveolar molding with active screw versus conventional...
Published 2025-08-01“…Abstract Objectives This study aimed to compare the 3D changes of maxillary arches in infants with bilateral cleft lip and palate (BCLP) undergoing vacuum formed nasoalveolar molding appliance with active screw (VF-NAM) to those who received conventional Grayson (G-NAM). Methods A total of 24 BCLP infants were randomly allocated into, group 1 (n = 12) who received V-NAM and Group 2 (n = 12) underwent G-NAM appliances. …”
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7640
Clinical characteristics, adherence to anticoagulation therapy and prognosis in patients with atrial fibrillation: a real-life study
Published 2025-04-01“…Methods Data from AF patients were collected in 2013, 2018, and 2023. …”
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