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7601
Emission Characteristics of Concrete Mixer Trucks Under Real-world Operating Conditions
Published 2025-03-01“…Most existing studies have primarily focused on heavy-duty freight vehicles, such as tractors, transport trucks, and dump trucks, while comparatively less attention has been given to concrete mixer trucks, which frequently operate in urban areas and pose potential threats to human health. …”
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7602
Evaluation of diabetes mellitus medication-taking behavior among first- and second-generation Australians of Chinese heritage: A nationwide cross-sectional study
Published 2025-06-01“…Conclusion: Medication beliefs play a role in sub-optimal medication-taking behavior among Chinese adults with T2DM. …”
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7603
Clinical decision support for pharmacologic management of treatment-resistant depression with augmented large language models
Published 2025-12-01“…A sample of community clinicians identified the optimal treatment choice for 12/91 vignettes (13.2 %, 95 % CI: 7.7–21.6 %; Cohen’s kappa = 0.10, 95 % CI 0.03–0.18), while an additional group of expert psychopharmacologists identified optimal treatment for 9/140 (6.4 %, 95 %CI: 3.4–11.8 %; Cohen’s kappa = 0.03, 95 % CI 0.01–0.08). …”
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7604
Silver nanoparticles as next-generation antimicrobial agents: mechanisms, challenges, and innovations against multidrug-resistant bacteria
Published 2025-08-01“…Despite their potent antibacterial activity, concerns regarding bacterial adaptation, cytotoxicity, and non-specific interactions have prompted extensive research into innovative delivery systems to enhance AgNP efficacy while minimizing adverse effects. This review comprehensively explores the synthesis methods and physical properties of AgNPs, emphasizing their antimicrobial mechanisms and emerging resistance patterns. …”
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7605
A machine learning approach to identifying key predictors of Peruvian school principals' job satisfaction
Published 2025-05-01“…SHAP analysis revealed that economic factors primarily influenced dissatisfied principals, while interpersonal factors were more important for highly satisfied principals, suggesting a hierarchical pattern of needs. …”
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7606
Micheliolide Alleviates Hepatic Fibrosis by Inhibiting Autophagy in Hepatic Stellate Cells via the TrxR1/2-Mediated ROS/MEK/ERK Pathway
Published 2025-02-01“…<b>Background</b>: Hepatic fibrosis is a major global health issue without an optimal drug treatment, highlighting the urgent need to find effective therapies. …”
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7607
Machine learning predicts improvement of functional outcomes in spinal cord injury patients after inpatient rehabilitation
Published 2025-08-01“…The ability to accurately predict functional outcomes for SCI patients is essential for optimizing rehabilitation strategies, guiding patient and family decision making, and improving patient care.MethodsWe conducted a retrospective analysis of 589 SCI patients admitted to a single acute rehabilitation facility and used the dataset to train advanced machine learning algorithms to predict patients' rehabilitation outcomes. …”
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7608
In how many patients urodynamics should be omitted? Data from a single-centre database on the basis of the upstream trial
Published 2025-06-01“…Results:: Among 212 patients analysed, 38.2% met all criteria for good surgical outcomes, while 61.8% exhibited at least one unfavourable criterion. …”
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7609
Research trends and hotspots of acupuncture for knee osteoarthritis from 2004 to 2024: a bibliometric analysis
Published 2025-06-01“…The journal Medicine published the most papers, while Osteoarthritis and Cartilage was the most cited (470 times). …”
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7610
Ultra-sensitive in situ detection of intracellular Mycobacterium tuberculosis with CRISPR/Cas12a
Published 2025-05-01“…The diagnostic performance was further validated using bronchoalveolar lavage fluid (BALF) samples from clinical participants, achieving a sensitivity of 94%, which surpassed conventional methods such as culture (67%) and Xpert (78%), while maintaining a specificity of 100%. …”
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7611
Cold storage of human precision-cut lung slices in TiProtec preserves cellular composition and transcriptional responses and enables on-demand mechanistic studies
Published 2025-02-01“…Moreover, TiProtec downregulated pathways associated with cell death, inflammation, and hypoxia while activating pathways protective against oxidative stress. …”
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7612
Comparison of efficacy and adverse effects of CD19/20 CART versus CD19 single-target CART in R/R DLBCL: a single-center retrospective study
Published 2025-05-01“…However, a subset of patients fails to achieve optimal outcomes with CD19-targeted CAR T-cells alone. …”
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7613
Options for postoperative radiation therapy in patients with de novo metastatic breast cancer
Published 2025-08-01“…Background: Although meta-analyses have demonstrated survival benefits associated with primary tumor resection in MBC, guidelines lack consensus on the survival benefit of postoperative radiation therapy (RT). Methods: In this study, we included 1392 patients with de novo metastatic breast cancer (dnMBC) by integrating data from the SEER database (2010–2019) to systematically assess the efficacy of postoperative RT and develop a machine learning-driven prognostic tool. …”
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7614
Primary cardiac sarcoma: insights from two decades of multimodal management at LMU Munich
Published 2025-06-01“…Methods Thirty-three patients diagnosed with PCS between 2002 and 2024 were retrospectively reviewed. …”
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7615
Re-sperm collection with a short abstinence time: a strategy for successful cryopreservation in cryptozoospermia
Published 2025-06-01“…Conclusions: These findings indicate that short-interval sperm collection enhances cryopreservation feasibility for cryptozoospermic patients without compromising post-thaw viability, potentially reducing reliance on invasive testicular sperm extraction. While larger prospective studies are needed to confirm these reproductive outcome benefits, this dual-collection protocol offers a cost-effective strategy to optimize sperm availability for intracytoplasmic sperm injection cycles in cases of severe male factor infertility. …”
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7616
Machine learning for detection of diffusion abnormalities-related respiratory changes among normal, overweight, and obese individuals based on BMI and pulmonary ventilation paramet...
Published 2025-07-01“…We evaluated the effectiveness of various supervised ML algorithms and identified the optimal configurations for these applications. Methods We conducted a retrospective analysis of data from 440 individuals who underwent pulmonary function tests between January 1, 2021, and April 1, 2024. …”
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7617
Effects of resistance exercise on patients with post-stroke dysphagia based on ACSM recommendations: a systematic review of randomized controlled trials
Published 2025-08-01“…BackgroundResistance exercise shows potential for improving swallowing function in post-stroke dysphagia (PSD), though optimal dose-response parameters remain unclear. While the American College of Sports Medicine (ACSM) framework effectively guides exercise prescriptions in healthy populations, its application to PSD rehabilitation lacks meta-analytical validation. …”
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7618
Pathophysiological Significance of Urea in Glomerular Filtration Dysregulation in Hepatorenal Syndrome: An Integrative Review
Published 2025-08-01“…Elevated urea levels above 35 mmol/L associate with a 3.42-fold increased mortality risk, while reductions exceeding 30% correlate with improved clinical outcomes, emphasizing the need for randomized trials targeting urea correction in HRS. …”
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7619
Comparative pharmacogenetic study of disulfiram or cyanamide efficacy for alcohol dependence: the key role of dopamine neurotransmission gene polymorphisms
Published 2023-07-01“…Materials and methods. A pharmacogenetic study was conducted on the basis of a double-blind, randomized, comparative, placebo-controlled clinical study of the efficacy and tolerability of disulfiram and cyanamide in the treatment of alcohol dependence syndrome. …”
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7620
Construction and application of a drought classification model for tea plantations based on multi-source remote sensing
Published 2025-12-01“…In the backdrop of global climate change, drought is identified as a major natural hazard, posing a severe threat to tea production. Traditional methods for assessing drought stress in tea plants rely on manual investigation. …”
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