Factors influencing clinical decision-making and health-related quality of life changes in colorectal cancer patients receiving targeted therapy: a multicenter study in China by Zeyang Li, Chengxi Feng, Hongwei Liu, Yin Liu, Huifang Xu, Yuqian Zhao, Xi Zhang, Yanqin Yu, Shaokai Zhang, Youlin Qiao

“…Abstract Objectives The aim of this paper is to assess the current clinical application of targeted therapy in colorectal cancer (CRC), identify factors influencing patients’ acceptance of targeted therapy, and evaluate its impact of targeted therapy on patients’ health-related quality of life (HRQoL). Methods This study was based on a national multi-center survey. …”
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Long-term straw return with moderate nitrogen levels reshapes soil bacterial communities in a vertisol by Zichun Guo, Rui Qian, Rui Qian, Rui Qian, Wei Li, Tianyu Ding, Tianyu Ding, Lei Gao, Lei Gao, Xinhua Peng

“…IntroductionIncorporating straw into the soil is a sustainable practice that can mitigate some of the adverse effects of excessive N fertilization on soil structure degradation and microbial diversity reduction.MethodsThis objective of this study was to determine the combined effects of straw management (straw return and straw removal) and N fertilization (0, 360, 450, 540, 630, and 720 kg N ha−1 yr.−1) on crop yields, soil properties, and soil microbial communities in a long-term wheat-maize cropping system.Results and discussionThe results showed that moderate N application (N450–N540) with straw return optimized wheat (283.5 kg ha−1) and maize (346.5 kg ha−1) yields, whereas higher N fertilization (N630, N720) led to soil acidification (pH decline of 0.51–1.67 units), irrespective of straw management. …”
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Dynamic control of upper limit for rainfall storing and effective use in rice paddies based on improved AquaCrop model by En Lin, Rangjian Qiu, Xinxin Li, Mengting Chen, Shizong Zheng, Fei Ren, Xiaoming Xiang, Chenglong Ji, Yuanlai Cui, Yufeng Luo

“…Yield losses across all scenarios remained below 3.00 %, confirming the strategy’s potential to optimize water management while minimizing adverse impacts on yield.…”
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Screening of Cellulase Producing Strains and Study on Their Enzymatic Properties by Shili WU, Yingying XIE, Xuening DUAN, Manshi YE, Weiqi XU, Guidong HUANG, Xianfeng ZHONG, Hong REN

“…The enzymatic properties of cellulase showed that: The optimal reaction temperature of extracellular cellulase was 50 ℃; the optimal pH was 5.5~6.5; the metal ions Cu2+, Ca2+, and Mg2+ had a promotional effect on the enzyme activity of three strains, of which Cu2+ had the strongest promotional effect, while Fe2+, Mn2+, Fe3+, and Ni+ had a different effect on the enzyme activity. …”
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Sistem Pendukung Keputusan untuk Penentuan Prioritas Pemberdayaan Masyarakat melalui Perilaku Hidup Bersih dan Sehat Menggunakan Metode Topsis by Alif Catur Murti, Ahmad Abdul Chamid

“…The TOPSIS method is used because it is able to find optimal alternatives based on ideal positive and negative distances. …”
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Enhanced Lightweight Quantum Key Distribution Protocol for Improved Efficiency and Security by Ashutosh Bhatia, Sainath Bitragunta, Kamlesh Tiwari

“…While the focus of this work is on the BB84 protocol, these optimizations are also directly applicable to a broader class of Discrete-Variable QKD (DV-QKD) protocols, such as six-state, B92, and E91, which share a fundamentally similar post-processing structure. …”
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Exploration on Cross-cultural Tolerance in Medical Care for Indigenous Tibetan Patients in Ultra-High-Altitude Areas by Feifei YU, Guangyong WANG, Jia WANG, LABUXIAGA, JIAYANGDUOJI, Yi XIE

“…Ultimately, it offered practical strategies to optimize the quality of medical services and provides insights and methods for healthcare support initiatives in ultra-high-altitude regions.…”
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Tracing Iridium Dissolution Pathways in Proton Exchange Membrane Water Electrolyzers at Relevant Current Densities in Real Time by Nico C. Röttcher, Jiahua Zhou, Lukas Löttert, Karl J. J. Mayrhofer, Dominik Dworschak

“…Discrepancies with so far reported findings from full‐cell and half‐cell experiments highlight a lack of understanding of catalyst dissolution and the transportation of dissolved species in different systems. The presented method offers unique insights which will help to study and optimize catalyst dissolution by means of various manufacturing and operation parameters to ultimately improve the stability of catalyst layers for water electrolysis.…”
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Economic Peaks and Value-at-Risk Analysis: A Novel Approach Using the Laplace Distribution for House Prices by Jondeep Das, Partha Jyoti Hazarika, Morad Alizadeh, Javier E. Contreras-Reyes, Hebatallah H. Mohammad, Haitham M. Yousof

“…The MO^<i>P</i> method aids in balancing the reliability goals while optimizing the performance in the face of uncertainty.…”
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Toward Low-Resource Languages Machine Translation: A Language-Specific Fine-Tuning With LoRA for Specialized Large Language Models by Xiao Liang, Yen-Min Jasmina Khaw, Soung-Yue Liew, Tien-Ping Tan, Donghong Qin

“…This study introduces Language-Specific Fine-Tuning with Low-rank adaptation (LSFTL), a method that enhances translation for low-resource languages by optimizing the multi-head attention and feed-forward networks of Transformer layers through low-rank matrix adaptation. …”
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Efficient high-resolution microscopic ghost imaging via sequenced speckle illumination and deep learning from a single noisy image by Sukyoon Oh, Sukyoon Oh, Tong Tian, Tong Tian, Zhe Sun, Christian Spielmann, Christian Spielmann

“…By utilizing sequenced random speckle patterns of optimized sizes, we reconstructed large noisy images with fewer patterns while successfully resolving fine details as small as 2.2 μm on a USAF resolution target. …”
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Tailored microstructure and enhanced bonding strength of in-situ surface modified Cu flakes via oxidation–reduction bonding by Siliang He, Xiangdong Liu, Zhiliang Pan, Sheng Gao, Yang Zuo, Hiroshi Nishikawa

“…The growth mechanism of oxide and its dominant diffusion method were detailed. The sintered Cu joint strength increases with increasing number of oxide grains, while excess oxides will cause coarsening of reduced Cu nanoparticles and degradation of joint strength. …”
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Influence of dry-wet cycles on the strength behavior of biopolymer and fiber composite modified loess by Zherui Liang, Changgen Yan, Yihan Cao, Yuling Shi, Han Bao, Huaixin Li

“…Frequent dry-wet cycles in the Loess Plateau region often trigger shallow slope instability and soil erosion, while conventional soil stabilizers face challenges of environmental pollution and insufficient durability. …”
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Fracture Resistance of Reattached Teeth: <i>In Vitro</i> Evaluation of Various Reattachment Techniques by Ankita Agrawal, Sandhya K Punia, Yogender Kumar, Shilpi Kushwaha, Deepak Sharma

“…Understanding the reattachment technique options helps clinicians provide the best care tailored to individual cases. Materials and methods: Thirty permanent maxillary central incisors were mounted in acrylic resin and divided into 3 groups (<i>n</i> = 10) based on reattachment methods: Group A (Control), group B (Chamfer), group C (Overcontouring). …”
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Hormonal, antioxidant, and body composition differences in national level male athletes: a comparative study of aerobic and anaerobic training by Manar Burhan Jaradat, Eyyad Maghayreh, Waqar Husain, Khaled Trabelsi, Khaled Trabelsi, Khaled Trabelsi, Adam Amawi, Haitham Jahrami, Haitham Jahrami, Hadeel Ali Ghazzawi

“…Ghrelin levels were significantly lower in the AS group (p &lt; 0.05), while leptin and GSH levels did not differ significantly between groups. …”
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Preventing Proximal Femur Pathologic Fractures Improves Outcomes in Patients with Metastatic Bone Disease: A Clinical Study Based on a Single Center Experience by Joana Páscoa Pinheiro, Mariana Nabais, André Spranger, Paulo Almeida, José Portela, Joaquim Soares do Brito

“…Twenty-nine patients presented pathologic fractures, while eight had an impending fracture. Twenty-six patients underwent osteosynthesis or conventional hemiarthroplasty/total hip arthroplasty, while an en bloc resection with megaprosthetic reconstruction was performed in the remaining 11 cases. …”
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A Segment Anything Model Approach for Rice Seedlings Detection Based on UAV Images by H. Rezvan, M. J. Valadan Zoej, F. Youssefi, F. Youssefi

“…Our findings reveal that the point prompt method emerges as the preferred choice for rice seedling detection, offering superior accuracy and reliability. …”
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Human–Seat–Vehicle Multibody Nonlinear Model of Biomechanical Response in Vehicle Vibration Environment by Margarita Prokopovič, Kristina Čižiūnienė, Jonas Matijošius, Marijonas Bogdevičius, Edgar Sokolovskij

“…Motion equations are derived using a second-order Lagrangian method; simulations are run using representative values of a typical car and human body segments. …”
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Application of numerical analysis and machine learning techniques to improve drying performance and energy consumption of microwave-assisted convective dryer by Hany S. El-Mesery, Ahmed H. ElMesiry, Mohammad Kaveh, Zicheng Hu, Abdallah Elshawadfy Elwakeel, Sara Elhadad

“…The combined microwave-hot air-drying technology is a modern okra drying method with significant research value and practical production potential. …”
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Numerical and Artificial Neural Network Analysis of Magnetohydrodynamic Natural Convection in a Nano-encapsulated Phase Change Suspension Filled Quadrantal Circular Enclosure by Mehdi Ghalambaz, Ioan Pop, Mikhail Sheremet, Mohammed Ali, Mohammad Ghalambaz

“…The governing equations for fluid flow and heat transfer of NEPCM suspension are introduced in the form of partial differential equations and were solved using the finite element method. The results showed that while an increase in the Rayleigh number augments heat transfer rates, a rise in the Hartmann number reduces it due to the Lorenz force's influence on fluid velocity. …”
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