Association of dietary quality, biological aging, progression and mortality of cardiovascular-kidney-metabolic syndrome: insights from mediation and machine learning approaches by Junfeng Ge, Lin Zhu, Sijie Jiang, Wenyan Li, Rongzhan Lin, Jun Wu, Fengying Dong, Jin Deng, Yi Lu

“…Abstract Background To investigate the association between the Dietary Inflammatory Index (DII), biological aging, and the staging and mortality of cardiovascular-kidney-metabolic (CKM) syndrome. Methods Data of 7,918 participants were derived from the National Health and Nutrition Examination Survey 2005–2018. …”
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Changes in Respiratory Function Before and After Cardiopulmonary Bypass in Children with Congenital Heart Disease with Increased or Decreased Pulmonary Blood Flow by Liang L, Hou A, Xi H, Yang J, Liu C

“…The external diameter of the pulmonary artery among patients in Group A was significantly larger than that in Group B (2.50± 0.38 vs 1.31± 0.29 cm, p < 0.05), while the external diameter of the aorta was significantly smaller in those in Group A compared to Group B (1.60± 0.26 vs 1.91± 0.37, p < 0.05). …”
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Bridging Knowledge Gaps: The Influence of Structured Education on Parental Knowledge and Attitude towards the Right to Education in Community by Neha Anil Katakwar, Darshana Wankhede, Bibin Kurian, Archana Maurya

“…Education plays a major role in creating an optimal environment and encouraging openness and effective governance within an entity. …”
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Intrathecal hydromorphone vs. transversus abdominis plane block for upper abdominal surgery: a propensity score-matching study by Yue-xin Huang, Yu Chen, Wei Wang, Ting-ting Li, Lin Ding, Fang Gao, Xiao-chuan Zou, Fei Liu

“…Abstract Background Multimodal analgesia is vital for enhanced recovery after upper-abdominal surgery. While both Intrathecal hydromorphone (ITH) and transversus abdominis plane (TAP) block are widely applied in upper-abdominal surgery, evidence comparing the two techniques remains limited. …”
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Analysis of mitochondrial-targeted antioxidant SkQ1 effectiveness on myocardial ischemia-reperfusion injury in a rat model: Focus on morphological and ultrastructural tissue study by E. A. Senokosova, E. A. Velikanova, R. A. Mukhamadiyarov, O. D. Sidorova, E. O. Krivkina, L. V. Antonova, E. V. Grigoriev

“…The quantitative data were processed using GraphPad Prism 7 (Graph Pad Software, USA).Results. The optimal myocardial preservation was discovered while using 12 ng/mL of SkQ1: the lowest concentrations of MDA (49.5 [41.1; 58.9] mmol/g), Troponin-I (22.3 [20.3; 23.9] pg/mL) and H-FABP (0.8 [0.6; 16.0] ng/mL) were associated with extensive areas of tissues with preserved transverse dark and light bands and a moderate interstitial edema. …”
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Exploring the Impact of Backward and Forward Locomotor Treadmill Training in Chronic Stroke Survivors with Severe Post-Stroke Walking Impairment: A Single-Center Pilot Randomized C... by Saiprasad Naidu, Khwahish Singh, Tamiel Murray, Colin Drury, Erin Palermo, Heidi J. Sucharew, Changchun Xie, Pierce Boyne, Kari Dunning, Oluwole O. Awosika

“…Future well-powered dosing trials and mechanistically driven studies are needed to optimize and identify predictors of training response.…”
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Clinical management and analysis of immune-related adverse events in neoadjuvant immunotherapy for locally advanced rectal cancer by AN Yang, WANG Chentong, QIU Xiaoyuan, ZHOU Jiaolin, LIN Guole

“…This study aimed to investigate the characteristics, clinical management strategies, and outcomes of irAEs during neoadjuvant immunotherapy for rectal cancer, providing a basis for optimizing irAEs monitoring and intervention. Methods: We retrospectively analyzed clinical data from LARC patients who developed irAEs after receiving neoadjuvant immunotherapy at Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, between July 2022 and June 2024. …”
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Pharmacokinetic Properties and Therapeutic Effectiveness of Remimazolam in ICU Patients With Mechanical Ventilation: A Preliminary Study by Jing Hu, Yuhan Zhao, Litao Shao, Wenhui Zhang, Han Wang, Yun Liu, Mengxiang Su, Xiangrong Zuo

“…ABSTRACT The pharmacokinetic (PK) profile of remimazolam, a ultra‐short‐acting benzodiazepine, has been investigated for procedural sedation and anesthesia, but its pharmacokinetics, pharmacodynamics, and optimal dosing for ICU sedation are still unclear. …”
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Augmenting Naïve Bayes Classifiers with <i>k</i>-Tree Topology by Fereshteh R. Dastjerdi, Liming Cai

“…In such cases, however, the selection of the <i>k</i> parent features for each variable is often made through heuristic search methods (such as sorting), which do not guarantee an optimal approximation of network topology. …”
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Edge-Deployed Band-Split Rotary Position Encoding Transformer for Ultra-Low-Signal-to-Noise-Ratio Unmanned Aerial Vehicle Speech Enhancement by Feifan Liu, Muying Li, Luming Guo, Hao Guo, Jie Cao, Wei Zhao, Jun Wang

“…Addressing the significant challenge of speech enhancement in ultra-low-Signal-to-Noise-Ratio (SNR) scenarios for Unmanned Aerial Vehicle (UAV) voice communication, particularly under edge deployment constraints, this study proposes the Edge-Deployed Band-Split Rotary Position Encoding Transformer (Edge-BS-RoFormer), a novel, lightweight band-split rotary position encoding transformer. While existing deep learning methods face limitations in dynamic UAV noise suppression under such constraints, including insufficient harmonic modeling and high computational complexity, the proposed Edge-BS-RoFormer distinctively synergizes a band-split strategy for fine-grained spectral processing, a dual-dimension Rotary Position Encoding (<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi>RoPE</mi></semantics></math></inline-formula>) mechanism for superior joint time–frequency modeling, and <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi>FlashAttention</mi></semantics></math></inline-formula> to optimize computational efficiency, pivotal for its lightweight nature and robust ultra-low-SNR performance. …”
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Dual Role of Quercetin in Promoting Early Wound Healing via Inhibiting Inflammatory Factors and Attenuating Scar Formation by Suppressing Myofibroblast Differentiation by Dan Wu, Mengyuan Jiang, Jing Zhang

“…Further efforts should focus on optimizing its bioavailability to enhance clinical translation.…”
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Randomized, controlled trial comparing the efficacy of intercostal nerve block in thoracoscopic surgery by timing: study protocol for a randomized clinical trial by Yasuharu Sekine, Hideo Ichimura, Sho Ueda, Shinsuke Kitazawa, Naohiro Kobayashi, Yuya Murata, Kumiko Yamada, Shinichi Inomata, Kazushi Maruo, Yukio Sato

“…Abstract Background Even minimally invasive thoracic surgeries carry a postoperative cost in pain. While regional anesthesia may alleviate this anticipated pain, especially intercostal nerve blocks (ICNB), the timing of block administration for optimal effect (at the beginning of surgery vs. before wound closure) remains controversial. …”
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Accuracy of 7 intraocular lens power calculation formulas in primary angle-closure glaucoma eyes, according to axial length and anterior chamber depth by Han Xu, Yuanjin Zheng, Xinlei Lu, Longyuan Liu, Rui Wan, Shaodan Zhang, Guoxing Li, Rongrong Le, Yuanbo Liang

“…Design Retrospective, consecutive case series. Methods Patients who underwent cataract surgery diagnosed with PACG or not were included. …”
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Intraoperative titration of positive end-expiratory pressure in urological patients undergoing laparoscopic procedures under lateral position: a randomized controlled trial by Lili Pan, Xing Wu, Lingling Gao, Zhanqi Zhao, Li Yang, Jun Zhang

“…Abstract Objective The study aimed to investigate the role of electrical impedance tomography (EIT)-guided individualized positive end-expiratory pressure (PEEP) in surgical patients under lateral position. Methods The urological patients undergoing elective laparoscopic surgery were randomly allocated to either the PEEPEIT (titrated with EIT) or PEEP5 (fixed PEEP = 5cmH₂O) groups. …”
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Direct comparison of cardioprotective effects of necroptosis inhibitors against global ischemia-reperfusion in the isolated rat heart by Yu. V. Dmitriev, S. M. Minasian, V. K. Bayrasheva, E. A. Demchenko, M. M. Galagudza

“…The study was aimed at comparative assessment of cardioprotective properties of various necroptosis inhibitors in the isolated perfused rat heart subjected to global ischemia-reperfusion.Materials and Methods. The study was performed on 38 male Wistar rats weighting 250–300 g. …”
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A nomogram for predicting malnutrition risk in patients with chronic heart failure and correlation study between GHRL, MSTN, CRP, Hs-CRP by Yuling Zha, Chengshuai Liu, Yuping Zhou, Miao Kong, Jinlei Liu, Lu Jing, Hailati Gulimila

“…Additionally, MSTN was positively correlated with CRP and Hs-CRP, while GHRL was negatively correlated with MSTN, CRP, and Hs-CRP. …”
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Perioperative temperature management and coagulation: effects of mild hypothermia in a prospective study by Alena Trčková, Tereza Bönischová, Tereza Bönischová, Hana Zelinková, Petr Štourač, Petr Štourač

“…The ROTEM results were abnormal in 18.7% of the patients, while the standard coagulation test showed abnormalities in 15.9% of the cases. …”
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Impact of SGLT2 inhibitors on survival in gastrointestinal cancer patients undergoing chemotherapy and/or radiotherapy: a real-world data retrospective cohort study by Lucas E. Flausino, Alexis Germán Murillo Carrasco, Tatiane Katsue Furuya, Wen-Jan Tuan, Roger Chammas

“…The intervention cohort consisted of Gl cancer patients who received SGLT2i, while the control cohort did not. A 5-year follow-up period was used, and baseline characteristics were balanced using a 1:1 propensity score matching technique. …”
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Intraoperative Intraluminal Endoscopy in the Surgical Treatment of Patients with Esophageal Diverticula of Various Localization by A. L. Shestakov, M. V. Khrustaleva, M. E. Shahbanov, N. A. Bulganina, T. T. Bitarov, I. A. Boeva, A. T. Tskhovrebov, I. A. Tarasova, O. V. Rykov, I. M. Selivanova, A. A. Bezaltynnykh

“…To improve the results of surgical treatment of patients with esophageal diverticulum of various localization using intraoperative intraluminal endoscopy. Materials and Methods: The Department of Surgery of the Esophagus and Stomach, the Petrovsky National Research Centre of Surgery, has accumulated a large experience in treating diverticulosis patients. …”
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AI-Driven Smart Agriculture: An Integrated Approach for Soil Analysis, Irrigation, and Crop-Fertilizer Recommendations by Ayesha Khaliq, Atif Khan, Salman Jan, Muhammad Umair, Asad Gulshair, Ahmad Ali, Usman Ali Shah

“…Modern agriculture faces critical challenges, including climate change induced water shortage, inefficient resource utilization, and reducing soil health which reduce sustainability and reduce crop yields. Traditional farming methods, dependent on manual observation and generalized practices, often lack the precision needed to address these growing issues. …”
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