Efficacy and safety of zanubrutinib combined with chimeric antigen receptor T-cell therapy targeting CD19 in refractory or relapsed diffuse large B cell lymphoma: A retrospective a... by Jinhuan Xu, Xiaoying Zhang, Yun Li, Fankai Meng, Yicheng Zhang, Miao Zheng

“…Background: While chimeric antigen receptor T-cell (CAR T) therapy has shown promise in treating B-cell non-Hodgkin lymphoma, its efficacy is variable in patients with poor initial responses. …”
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Developing a Machine Learning Model for Predicting 30-Day Major Adverse Cardiac and Cerebrovascular Events in Patients Undergoing Noncardiac Surgery: Retrospective Study by Ju-Seung Kwun, Houng-Beom Ahn, Si-Hyuck Kang, Sooyoung Yoo, Seok Kim, Wongeun Song, Junho Hyun, Ji Seon Oh, Gakyoung Baek, Jung-Won Suh

“…Among 46,225 patients of the Seoul National University Bundang Hospital, MACCE occurred in 4.9% (2256/46,225), including myocardial infarction (907/46,225, 2%) and stroke (799/46,225, 1.7%), while in-hospital mortality was 0.9% (419/46,225). …”
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Stress state calculation and potential failure risk identification of LNG storage tank inlet pipeline by Yanbing WANG, Hong ZHANG, Mengying XIA, Hongyu ZHOU, Baisong LI, Qiyu HUANG, Xiaoben LIU

“…Identifying potential failure risks in the pipeline is essential for ensuring the safe operation of the LNG storage tank. MethodsTaking the inlet pipeline of a LNG terminal storage tank as an example, a numerical calculation model was developed for the temperature field of the pipeline. …”
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The contribution of personalized video feedback to robotic partial nephrectomy training in realistic 3D tumor kidney models: design, production and implementation by Ahmet Furkan Sarıkaya, Kayhan Tarım, Ersin Köseoğlu, Arif Özkan, İbrahim Can Aykanat, Baris Esen, Umut Can Karaarslan, Mustafa Müdüroğlu, Şevval Kanlı, Murat Can Kiremit, Yakup Kordan, Mevlana Derya Balbay, Tarık Esen, Serdar Aydın, Serdar Aydın, Abdullah Erdem Canda, Abdullah Erdem Canda

“…This study investigates the impact of 3D-printed renal models and video-based feedback on skill acquisition in robotic partial nephrectomy training.MethodsForty urology residents without prior robotic surgery experience participated in this study. …”
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Rapid Initiation of Antiretroviral Therapy Suppresses T Cell Pathological Proliferation and Improves Immune Recovery in People Living with HIV by Ji J, Guo C, Li Z, Cai M, Wang R, Chen X, Zhang Y, Wu H, Zhang T, Zhang Y

“…Additionally, CD8⁺ T cells in the rapid ART group exhibited an increased presence of TN cells while showing a decreased proportion of PD-1/HLA-DR/CD38 high-expressing cells. …”
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Trend analysis of pulmonary tuberculosis incidence among the elderly in Shanghai， 2014‒2023 by HUANG Yu, RAO Lixin, XU Biao, ZHAO Qi, SHEN Xin

“…ObjectiveTo describe the epidemiological characteristics and trend of pulmonary tuberculosis among the elderly in Shanghai from 2014 to 2023, to estimate the incidence between 2024‒2025, so as to provide references for optimizing the prevention and control strategies of pulmonary tuberculosis for elderly in Shanghai.MethodsData of pulmonary tuberculosis patients aged ≥60 years in Shanghai registered in the Tuberculosis Registration and Management System of Chinese Center for Disease Control and Prevention from 2014 to 2023 was derived to describe the demographic characteristics of the elderly patients with pulmonary tuberculosis, and to calculate the reported incidence rate and annual percentage change (APC) of pulmonary tuberculosis. …”
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Comparative effectiveness and safety of tenofovir alafenamide versus tenofovir disoproxil fumarate in patients with HBV-associated decompensated cirrhosis: insights from a retrospe... by Lu Chen, Hui-Fang Zhang, Yi-Jing Cai, Lei Zhang, Chao Cai, Ming-Qin Lu, Yue-Ying Zhu

“…Given the severity of decompensated cirrhosis, selecting the most appropriate first-line antiviral medication is crucial for optimizing treatment outcomes and providing the best possible disease control. …”
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How does social support influence autonomous physical learning in adolescents? Evidence from a chain mediation and latent profile analysis. by Jiamin Zhu, Ziyou Huang, Xiaoping Meng, Zhiyong Zhang, Xiaotong Yuan

“…The goal is to provide insights into how social support can enhance adolescents' engagement in physical activities and inform intervention strategies.<h4>Methods</h4>A total of 2,359 junior high school students (1,208 males and 1,151 females; mean age = 13.21 ± 0.96 years) from three public schools in Shandong Province were surveyed between October and December 2024. …”
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Comparison of efficacy of exosomes derived from human umbilical cord blood mesenchymal stem cells in treating mouse acute lung injury via different routes by Jing Chen, Jing Chen, Shuang Liu, Jizhen Zou, Yi Wang, Haiyan Ge, Yi Hui, Siyuan Huang, Wei Li, Weilan Na, Xiaolan Huang, Lin Bai, Yiying Huang, Dong Qu

“…ObjectiveTo investigate the therapeutic efficacy of human umbilical cord blood mesenchymal stem cell-derived exosomes (hUCMSC-Exo) in a lipopolysaccharide (LPS)-induced acute lung injury (ALI) mouse model and compare the effects of different administration routes.MethodsAn ALI mouse model was established through intratracheal LPS injection. …”
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Temporal evolution and factors influencing visual function and RNFL thickness in ethambutol-associated optic neuropathy by Taimin Guo, Yue Fu, Xiaoyu Xu, Xiaoning Liu, Yurong Zhang, Hui Yang

“…Abstract Purpose This study aimed to investigate the temporal evolution and influencing factors of visual function and optic nerve structure in ethambutol-associated optic neuropathy (EON). Methods In this single-center retrospective observational study, we analyzed data from 48 EON patients (26 males and 22 females) with a 12-month follow-up. …”
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Effects of Regulated Deficit Irrigation on Leaf Nutrients, Enzyme Activities, and Root Zone Soil Nutrients during Fruit Expansion and Coloration-Sugar Accumulation Stages of Citrus... by ZHONG Yun, HUANG Zhikun, ZHU Shijiang, HAO Kun, ZHU Zirong, ZHANG Wei, CHEN Hongde

“…The findings provide a theoretical basis for optimizing citrus irrigation practices and improving fruit quality.…”
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Effect of Probiotic Supplementation on Maternal Depression, Anxiety and Attachment in Gestational Diabetes by Improving Mediterranean Diet Quality: A Randomized Controlled Trial by Fatma Bengü Kuyulu Bozdoğan, Seray Kabaran, Aybala Tazeoğlu

“…Considering the impact of probiotics on mental health, our study aimed to answer the question of whether probiotic supplementation is effective on depression and anxiety in women with gestational diabetes. Methods: In this randomized controlled study with an allocation ratio of 1:1, the participants were divided into two groups: control group, received standard diet compatible with Mediterranean diet (MD) while the probiotic supplementation group received both the standard diet compatible with MD and probiotic supplementation (Lactobacillus acidophilus, Lactobacillus rhamnosus, Bifidobacterium bifidum, Bifidobacterium longum and Enterococcus faecium). …”
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Clinical Implications of Urinary C-Peptide Creatinine Ratio in Patients with Different Types of Diabetes by Yanai Wang, Ying Gao, Xiaoling Cai, Ling Chen, Lingli Zhou, Yumin Ma, Siqian Gong, Xueyao Han, Linong Ji

“…The UCPCR was lower in patients with T1DM compared with T2DM, monogenic diabetes, and healthy subjects, while the UCPCR was similar in T2DM and monogenic diabetes. …”
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Efficient Sleep, Enhanced Attention: Exploring the Interplay With RBC-Inflammation Mechanisms in Hypoxic High-Altitude Areas by Shi CY, Xue XJ, Li ZF, Huang XY, Su R, Wang NN, Zhu JG, Li H, Ma HL, Liu M, Zhang DL

“…Sleep quality was evaluated using the Pittsburgh Sleep Quality Index, while the Symptom Check-List-90 and a standard physical examination measured overall health status. …”
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Influence of Fermentation of Eurotium cristation on the Flavor Characteristics of Guizhou White Tea by Jinlong LUO, Zhongying LIU, Shimao FANG, Tuo ZHANG, Yuqiao DAI, Xiaowei YANG, Ting YANG, Mengzhen ZHU, Qiang SHEN

“…Specifically, the color of the tea deepened, while freshness diminished; conversely, sweetness and smoothness were enhanced. …”
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GPD2 inhibition impairs coagulation function via ROS/NF-κB/P2Y12 pathway by Jiajie Chen, Guifeng Xu, Zhipeng Xie, Shaoxia Xie, Wenwei Luo, Shilong Zhong, Weihua Lai

“…However, the therapeutic efficacy of ticagrelor is compromised by interindividual variability in bleeding risk. Notably, while inherited genetic variations account for part of this heterogeneity, the dynamic regulatory role of modifiable epigenetic mechanisms—particularly DNA methylation in mediating platelet reactivity—remains inadequately characterized, presenting a critical knowledge gap in optimizing precision antiplatelet strategies. …”
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Abstract 014: Beveled‐Tip Aspiration Catheters Reduce Stoke Procedure Time And Cost For Large And Medium Vessel Occlusions by Mohamad M. Ezzeldin, Riichi Ota, Eric Riha, Adam Delora, Bader Alenzi, Victoria Gordon, Himanshu Gupta, Rime Ezzeldin, Saif Bushnaq

“…The angled‐tip configuration is engineered to enhance device trackability and optimize clot engagement. Following promising initial results observed during our catheter evaluation, we integrated these novel catheters into the majority of thrombectomy procedures at our institution. …”
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Antifungal susceptibility and clinical efficacy of chlorhexidine combined with topical ophthalmic medications against Fusarium species isolated from corneal samples by Min Kang, Yuxuan Wu, Qingquan Shi, Zhiqun Wang, Yang Zhang, Kexin Chen, Xizhan Xu, Man Zhou, Qingfeng Liang, Xinxin Lu

“…And to explore the clinical feasibility of combination therapy in the treatment of corneal infections caused by F. solani, with the goal of optimizing the treatment regimen for fungal keratitis.MethodsA total of 194 strains of Fusarium were isolated from the corneas between 2013 and 2024 and identified to the species level using mass spectrometry. …”
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Research on the association of breast cancer patients’ prognosis with internal mammary sentinel lymph node biopsy by JIA Ruijie, SHI Zhiqiang, ZHANG Qi, LU Yongjin, ZHENG Junsheng, SUN Jing, BI Zhao, SUN Xiao, WANG Yongsheng, QIU Pengfei

“…The purpose of this study was to investigate the prognosis of IMSLNB in early breast cancer. Methods: In this study, a retrospective cohort of 7 949 patients with breast cancer from January 1, 2016 to December 31, 2021 was analyzed. …”
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Efficacy and Safety of Epi-On vs Epi-Off Corneal Cross-Linking in Corneal Ectasia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Nughays RO, Bazayd AS, Alshamekh LA, Alshammari RA, Alenezi MA, Dahlan HY, Alsubhi JA, Alshammri SG, AlQurashi NA, Aldajani AH, Alrammah AH, Alenezi MN, Almutairi AA, Alomayri AF, Alghamdi S

“…This review highlights the need for further studies to optimize CXL approaches and improve outcomes while minimizing complications.Keywords: corneal ectasia, corneal collagen cross-linking (CXL), epi-on, epi-off, keratoconus, maximal keratometry (Kmax), visual acuity, endothelial cell count (ECC)…”
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