Outcomes of Implementing a Multidimensional Antimicrobial Stewardship Program in a Medical Ward in a Third-Level University Hospital in Northern Italy by Maria Mazzitelli, Daniele Mengato, Gianmaria Barbato, Sara Lo Menzo, Fabio Dalla Valle, Margherita Boschetto, Paola Stano, Cristina Contessa, Daniele Donà, Vincenzo Scaglione, Giacomo Berti, Elisabetta Mariavittoria Giunco, Tiziano Martello, Francesca Venturini, Ignazio Castagliuolo, Michele Tessarin, Paolo Simioni, Annamaria Cattelan

“…<b>Background/Objectives</b>: Antimicrobial stewardship programs (ASPs) optimize antimicrobial use, improving outcomes and reducing resistance. …”
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Exploring the role of community pharmacists in addressing obesity: a Saudi Arabian perspective by Othman AlOmeir, Mansour Almuqbil, Hanaa Ali Alhabshi, Maha Mahrab Saiel Alenazy, Saleha Mafareh Al-Jaro Masaod Hagwi, Walaa F. Alsanie, Walaa F. Alsanie, Abdulhakeem S. Alamri, Abdulhakeem S. Alamri, Majid Alhomrani, Majid Alhomrani, Amal F. Alshammary, Rafiulla Gilkaramenthi, Syed Mohammed Basheeruddin Asdaq, Syed Mohammed Basheeruddin Asdaq

“…This study aimed to explore the beliefs, practices, and barriers encountered by community pharmacists in Saudi Arabia regarding weight management.MethodsA cross-sectional survey was conducted among community pharmacists to gather data on their perceptions, practices, and barriers related to obesity management. …”
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Gymnadenia conopsea orchid: a systematic review by Jing-Yi Wu, Jing-Yi Wu, Ruo-Nan Tang, Ruo-Nan Tang, Jia-Wen Wang, Jia-Wen Wang, Wan-Ying Chen, Wan-Ying Chen, Xing Liu, Ji-Wen Wang, Mei-Ya Li, Fu-Sheng Jiang, Fu-Sheng Jiang

“…For propagation, wild-simulated cultivation should be adopted for resource conservation, while optimizing symbiotic germination techniques is critical to overcome propagation bottlenecks, ultimately enabling sustainable utilization.…”
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The Extended Flexor Carpi Radialis Approach for Distal Radius Fracture Fixation: A Prospective Study by Sulaiman Alrefai, MD, Dionne Hsu, MD(c), Jonathan Persitz, MD, Atefeh Noori, PhD, Andrea Chan, MD, FRCSC, Ryan Paul, MD, FRCSC

“…This approach ensures optimal radial and dorsal exposure by releasing the radial septum and simplifies reduction by releasing deforming forces while providing access to the critical volar ulnar corner. …”
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Age-Onset-Related Particularities of Pediatric MS—Understanding the Spectrum: A Tertiary Center Experience by Alice Denisa Dică, Dana Craiu, Florentina Ionela Linca, Magdalena Budișteanu, Catrinel Iliescu, Carmen Sandu, Cristina Pomeran, Diana Bârcă, Niculina Butoianu, Carmen Burloiu, Ioana Minciu, Ina Ofelia Focșa, Dana Surlică, Oana Tarța-Arsene, Cristina Cazacu, Andreea Badea, Alexandru Stefan Niculae, Daniela Adriana Ion

“…Further multicenter studies with standardized imaging and cognitive assessment protocols are needed to optimize care for this vulnerable population.…”
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Galactomannan detection in sputum samples of patients with chronic obstructive pulmonary disease: A promising marker for diagnosis of chronic pulmonary aspergillosis? by Sabrieh Asadi Shahi Sarae, Masoud Aliyali, Vida Mortezaee, Hamidreza Jamaati, Hossein Asgarian Omran, Siavash Abedi, Hossein Mehravaran, Jamshid Yazdani Charati, Maryam Sadat Mirenayat, Mihan Pourabdollah, Kosar Najmi, Sabah Mayahi, Mona Ghazanfari, Ahmed Al-Harrasi, Mahdi Abastabar, Mohammad T. Hedayati, Abdullah M.S. Al Hatmi

“…Background and purpose: Diagnosing chronic pulmonary aspergillosis (CPA) is challenging due to nonspecific symptoms, variable radiological findings, and limited mycological evidences. While galactomannan (GM) testing has been validated in serum and bronchoalveolar lavage fluid (BAL) for invasive pulmonary aspergillosis (IPA), its usefulness in sputum samples for CPA remains unclear. …”
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Impact of Storage Conditions on Bronchoalveolar Lavage Fluid Analysis: A Human Study by Yu Shionoya, Kanae Maruyama, Takeshi Kawasaki, Mayumi Ono, Yushi Murai, Ryutaro Hirama, Dai Horiuchi, Noriko Sakuma, Shinsuke Kitahara, Shun Sato, Kohei Takahashi, Yoshihito Ozawa, Takuji Suzuki

“…This study aimed to evaluate how different storage conditions impact BALF cell counts and differentials to guide optimal sample handling practices. <b>Methods</b>: Forty patients who underwent BAL at Chiba University Hospital from June to December 2024 were included. …”
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Cost analysis of four surgical techniques for pediatric inguinal hernia repair in a Dutch hospital by Roxanne Eurlings, Merel L. Kimman, Lloyd Brandts, Ruben G.J. Visschers, Wim G. van Gemert

“…Introduction: Pediatric inguinal hernia repair (IHR) can be performed using open repair, laparoscopic approaches such as percutaneous internal ring suture (PIRS) or conventional laparoscopic IHR (LIHR) with N-/Z-suture, and robot-assisted IHR (RIHR). While extensive literature on clinical outcomes exists, cost data remain scarce. …”
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Factors influencing nutrition literacy in patients of colorectal cancer: a cross-sectional study by Jing Zhang, Jing Zhang, Dan Li, Dan Li, Dan Li, Jiai Yan, Jiai Yan, Ju Yang, Ju Yang, Jing Sun, Jing Sun, Jing Sun, Yiran Liu, Yiran Liu, Yanping Xia, Yanping Xia, Yanping Xia, Hong Cao, Hong Cao, Hong Cao, Jiao Hua, Feng Zhang, Feng Zhang, Feng Zhang, Yingyu Wang, Yingyu Wang

“…This study aims to evaluate the level of NL in colorectal cancer patients and identify key factors influencing NL.MethodsA total of 245 colorectal cancer patients participated in this study. …”
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The effects of clinical crown length on the sagittal movement of maxillary central incisor in clear aligner treatment: a finite element exploration by Chen Zhou, Zhicai Feng, Jianhan Ren, Haotian Luo, Hio Cheng Ieong, Runze Li, Yangqiao Qing, Yuqing Guo, Bingyan Guo, Zichun Huang, Yang Cao, Weicai Wang

“…Labio-lingual attachment had the optimal effect in tipping and translational movement. …”
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Lower body mass index is associated with the achievement of target LDL in patients using PCSK9 inhibitors in Taiwan by Kuan-Chieh Tu, Wei-Ting Chang, Hui-Wen Lin, Po-Lin Lin, Yen-Wen Wu, Chao-Feng Lin, Hung-I. Yeh, Min-Ji Charng, Po-Hsun Huang, Tsung-Hsien Lin, Wei-Wen Lin, I.-Chang Hsieh, Feng-Yu Kuo, Ching-Pei Chen, Sheng-Hsiang Lin, Yi-Heng Li

“…These findings support personalized strategies for optimizing cholesterol management in statin-intolerant patients while further investigations are required. …”
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Increased autophagy activity regulated by LC3B gene promoter DNA methylation is associated with progression to active pulmonary tuberculosis disease by Yung-Che Chen, Ying-Tang Fang, Chao-Chien Wu, Tung-Ying Chao, Yi-Hsi Wang, Chia-Cheng Tseng, Sum-Yee Leung, Chiu-Ping Lee, Ting-Ya Wang, Po-Yuan Hsu, Jen-Chieh Chang, Meng-Chih Lin, Chang-Chun Hsiao

“…Conclusions Increased LC3B expression and LC3B gene promoter hypermethylation may serve as biomarkers for progression of M. tb infection, while use of de-methylation agent may be a potential approach to host-directed immunotherapy in active TB disease.…”
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Atrial Fibrillation Termination Success During Ablation: Insights From Pooled Clinical Studies by Changjian He, Wenchang Zhang, Feng Li, Huaiqiang Wang, Xiongyi Han, Zihan Zhao, Guojie Ye, Tengfei Liu, Da Zhang, Haiyan Liu, Jie Liu, Jingning Zhao, Chunhua Ding

“…Background: The optimal endpoint for ablation in persistent atrial fibrillation (pers-AF) remains unclear. …”
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Contribution of Human Resources for Health competence and skill mix on compliance with healthcare quality standards among Primary Healthcare Facilities in Tanzania: evidence from d... by Syabo M. Mwaisengela, Patricia A. Materu, Chrisogone J. German, Issa I. Mmbaga, Danny J. Temba, Raymond R. Kiwesa, Martin S. Mapunda, Erick S. Kinyenje, Nathanael Sirili, Pankras W. Luoga, Simon P. Ernest, Joseph M. Burra, Joseph C. Hokororo, Godfrey Kacholi, Ntuli A. Kapologwe, Mackfallen G. Anasel, Claud J. Kumalija, Michael Habtu, Grace E. Saguti, Janeth S. Masuma, Talhiya A. Yahya, Eliudi S. Eliakimu

“…Proportions of skill mix status and compliance with HCQS were compared by chi square test while Prevalence Ratios were estimated by Multivariable Poisson Regression with 95% Confidence Interval. …”
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Comparative Analysis of Gut Microbiota Diversity Across Different Digestive Tract Sites in Ningxiang Pigs by Wangchang Li, Xianglin Zeng, Lu Wang, Lanmei Yin, Qiye Wang, Huansheng Yang

“…Understanding the structure and function of tissue-specific microbial communities in Ningxiang pigs is essential for optimizing their growth, development, and nutritional efficiency. …”
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Impacts of Traditional Warm-Up and Post-Activation Potentiation on Muscle Endurance During the Back Squat: Response of Blood Lactate, Perceived Effort, and Time Under Tension by Taianda M. Amorim, Alexandre V. Gurgel, Viviane Faleiro, Thiago T. Guimarães, Estêvão R. Monteiro, Felipe G. Teixeira, Bruno Jotta, Tiago C. Figueiredo, Raquel C. Castiglione, Silvio R. Marques-Neto

“…Background: Warm-up strategies are essential for optimizing strength-training performance. Traditional warm-ups improve neuromuscular readiness, whereas post-activation potentiation (PAP) has been proposed to acutely enhance muscular output. …”
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Evaluating Maize Residue Cover Using Machine Learning and Remote Sensing in the Meadow Soil Region of Northeast China by Zhengwei Liang, Jia Du, Weilin Yu, Kaizeng Zhuo, Kewen Shao, Weijian Zhang, Cangming Zhang, Jie Qin, Yu Han, Bingrun Sui, Kaishan Song

“…By comparing the accuracy of these methods, the most accurate model was determined and applied to subsequent CRC estimation. …”
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Multi-omics dissection of metabolic dysregulation associated with immune recovery in people living with HIV-1 by Lin-Yu Wan, Sin Man Lam, Hui-Huang Huang, Wen-Jing Cao, Xiang-Yi Cao, Xue-Meng Li, Li-Ping Zhang, Jia-Min Gao, Chao Zhang, Xing Fan, Yan-Mei Jiao, Guanghou Shui, Fu-Sheng Wang, Jin-Wen Song

“…Abstract Background Despite the success of antiretroviral therapy (ART) in suppressing HIV-1 replication, some people living with HIV-1 (PLWH) fail to achieve an optimal recovery of CD4 T cells, and precise metabolic regulation underlying immune recovery remained poorly understood. …”
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Assessment of salt tolerance in peas using machine learning and multi-sensor data by Zehao Liu, Qiyan Jiang, Yishan Ji, Rong Liu, Hongquan Liu, Xiuxiu Ya, Zhenxing Liu, Zhirui Wang, Xiuliang Jin, Tao Yang

“…The results show that: 1) multi-source data fusion significantly improved the accuracy of AGB and SPAD estimation; 2) the CatBoost algorithm achieved the highest performance for AGB estimation (R² = 0.70, RMSE = 1.59 t/hm2, NRMSE = 13.94 %), while the LightGBM algorithm performed best for SPAD estimation (R² = 0.60, RMSE = 2.33, NRMSE = 14.53 %); and 3) The PSTS established based on the optimal estimation data exhibits a strong consistency with the ground-measured data. …”
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Clinical features of non-compaction cardiomyopathy across age groups: a retrospective study of 415 patients by Ying Li, Jimei Chen, Min Qiu, Miao Tian, Ziqin Zhou, Ruyue Zhang, Jiazichao Tu, Linjiang Han, Shuheng Zhou, Xinming Li, Jian Zhuang, Shusheng Wen

“…Notably, heart failure was most prevalent in adult patients (54.6%, n=53), while cardiac murmur was the primary presenting symptom in both infant and child/adolescent groups (19.5%, n=33 and 17.4%, n=26, respectively). …”
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