Venous thromboembolism in patients undergoing pancreatic cancer surgery (PaTR-VTE) with curative intent; protocol of a prospective observational study by Maria P. Ntalouka, Dimitrios Symeonidis, Paraskevi Kotsi, Efthymia Petinaki, Miltiadis Matsagkas, Konstantinos Tepetes, Dimitrios Zacharoulis, Eleni M. Arnaoutoglou

“…The results could lead to an optimization of perioperative care. Trial registration NCT05964621. …”
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Effectiveness of Stress Shielding Prevention Using a Low Young’s Modulus Ti-33.6Nb-4Sn Stem: A 7-Year Follow-Up Study by Kazuyoshi Baba, Yu Mori, Hidetatsu Tanaka, Ryuichi Kanabuchi, Yasuaki Kuriyama, Hiroaki Kurishima, Kentaro Ito, Masayuki Kamimura, Daisuke Chiba, Toshimi Aizawa

“…Background: Stress shielding (SS) after total hip arthroplasty (THA) leads to proximal femoral bone loss and increases the risk of complications such as implant loosening and periprosthetic fracture. While various low-stiffness stems have been developed to prevent SS, they often compromise mechanical stability. …”
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Systematic review and meta analysis of mechanical properties of 3D printed denture bases compared to milled and conventional materials by Amr Azab, Walid Awad Abdelhady, Enas Elwakeel, Mohamed Ashraf, Rim Wally, Amir Soliman, Maged Ahmed Mohamed, Dina Abozaid

“…Milled denture bases exhibited the highest FS (120–146 MPa), followed by conventional PMMA (95–119 MPa), while 3D-printed bases showed wider variability (28–128 MPa). …”
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Alginate-hydroxyapatite scaffolds: A comprehensive characterization study by Saanvi Gupta, Suganya Panneer Selvam, Ramya Ramadoss, Sandhya Sundar

“…Their porous architecture, combined with embedded HA, enhances mechanical stability while providing essential biochemical cues for cell proliferation and mineralization. …”
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MicroRNAs as regulators of NLRP3 inflammasome activation in herpes simplex virus type 2 infection by Debashree Dass, Debashree Dass, Anwesha Banerjee, Ashwini More, Anupam Mukherjee, Anupam Mukherjee, Anupam Mukherjee, Anupam Mukherjee

“…Future research should focus on in vivo validation and therapeutic optimization to develop miRNA-based interventions.…”
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Retrospective analysis of open reduction and locking plate fixation in three and four part proximal humeral fractures with efficacy and complications by Haiqiang Ma, Jianbin Sun, Xu Ma, Zhipeng Yang, Huanhuan Sun, Donghui Cao, Liangguo Si, Peijie Zhao, Zewen Qiao

“…Their occurrences were highly correlated with factors such as age, diabetes, osteoporosis, fracture healing time, rotator cuff repair, rehabilitation methods, medial cortical bone defect, calcar screw, calcar distance, calcar ratio, reduction quality, and so on. …”
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A Pragmatic Clinical Trial to Compare the Real-World Effectiveness of V-Go versus Standard Delivery of Insulin in Patients with Advanced Type 2 Diabetes by Mark J. Cziraky, Scott Abbott, Matt Nguyen, Kay Larholt, Elizabeth Apgar, Thomas Wasser, Poul Strange, Leon Shi, H. Courtenay Harrison, Beverly Everitt, Lynn Nowak

“…. # Methods Study sites, rather than individual patients, were randomized to V-Go or STO via cluster randomization. …”
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Auto-Segmentation and Auto-Planning in Automated Radiotherapy for Prostate Cancer by Sijuan Huang, Jingheng Wu, Xi Lin, Guangyu Wang, Ting Song, Li Chen, Lecheng Jia, Qian Cao, Ruiqi Liu, Yang Liu, Xin Yang, Xiaoyan Huang, Liru He

“…The auto-planning process required 1–3 optimization iterations for 50%, 40%, and 10% of cases, respectively, and exhibited significant better conformity (<i>p</i> ≤ 0.01) and OAR sparing (<i>p</i> ≤ 0.03) while maintaining comparable target coverage. …”
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Midterm outcomes of Bentall procedure versus isolated aortic valve replacement for bicuspid aortic valve with severe stenosis and ascending aortic dilation by LI Shijie, LI Tianbo, YANG Zhipeng

“…But, Bentall procedure offers advantages in hemodynamic optimization and aortic stability. …”
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Pre-pregnancy fertility guidance for women of childbearing age with epilepsy: A scoping review by Liu Siqin, Song Jia, Huang Shiming, Yuan Xiaoli, Peng Yan, Gu Congcai, Xu Zucai

“…Two researchers with evidence-based nursing backgrounds independently completed literature screening and quality evaluation while extracting and summarizing evidence based on themes. …”
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Surgical implants in animal models for male and female infertility: A translational approach by S. Bharath, A.S. Vickram, B. Bhavani Sowndharya, C. Prasanth, D. Jenila Rani, G. Gulothungan, Hitesh Chopra, Tabarak Malik

“…For female infertility, ovarian implants have been shown to support follicular growth, while fallopian tube and uterine prostheses facilitate embryo transfer and implantation. …”
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Maternal health education and social support needs across the perinatal continuum of care: a thematic analysis of interviews with postpartum women in Punjab, India by Preetika Sharma, Rashmi Bagga, Maliha Khan, Mona Duggal, Darshan Hosapatna Basavarajappa, Alka Ahuja, Ankita Kankaria, Nadia Diamond-Smith, Vijay Kumar, Manju Kashyap, Pushpendra Singh, Jasmeet Kaur, Alison M. El Ayadi

“…Abstract Background Perinatal social support and maternal education throughout the antenatal, childbirth, and postpartum phases contribute to the optimization of health and well-being of mothers and infants. …”
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Research on the Pattern Evolution of Innovation Output Space in Guangzhou Metropolitan Area Based on Authorized Invention Patent Data by Shan Zhuoran, Liu Sisi, Yuan Man, Zhu Junqing

“…Based on the data of authorized invention patents in the Guangzhou metropolitan area, this study applied spatial research methods, such as spatial autocorrelation, kernel density analysis, and buffer analysis, to explore the overall evolution pattern of innovation output space in the metropolitan area as well as the evolution characteristics and influencing factors of the three types of innovation outputs, namely enterprises, scientific research institutions, and individuals, to provide a scientific basis for the development of innovation space and the optimization of innovation resources. …”
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Low Saturation Confidence Distribution-based Test-Time Adaptation for cross-domain remote sensing image classification by Yu Liang, Shilei Cao, Juepeng Zheng, Xiucheng Zhang, Jianxi Huang, Haohuan Fu

“…LSCD-TTA adapts a source-trained model on the fly using only the target test data encountered during inference, enabling immediate and efficient adaptation while maintaining high accuracy. Specifically, LSCD-TTA incorporates three optimization strategies tailored to the distribution characteristics of RS images. …”
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Overcoming challenges of developing a live-attenuated dengue vaccine and the path forward by Dr Walid Kandeil, Dr Mayuri Sharma

“…Results: Based on the single backbone of DENV-2 with chimeric DENV-1, -3, and -4 elements and three stable mutations in the 5′untranslated region and the NS genes (NS1 and NS3), TAK-003 demonstrated a balance between immunogenicity and reactogenicity while eliciting high rates of seroconversion in baseline (before vaccination) seronegative participants with low rates and levels of vaccine-induced viremia, indicating optimal attenuation. …”
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Factors influencing immunization record retrieval from immunization information systems among independent community pharmacies: A National Survey by Oluchukwu M. Ezeala, Nicholas P. McCormick, Christopher L. Meininger, Hannah Fish, John Beckner, David Ha, Rebecca Snead, Heather Vance, Salisa C. Westrick

“…Results: Approximately 65 % of the respondents were high IIS users (“frequently”/“always”) while 35 % were low IIS users (“never”/“rarely”/“occasionally”). …”
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General practitioners’ scanning competence following tailored ultrasound training: a hybrid effectiveness-implementation study by Camilla Aakjær Andersen, Søren Lundbye-Christensen, Allan Riis, Ulrike Mehnert, Thomas Løkkegaard, Troels Mengel-Jørgensen, Liv Dyre Rasmussen, Nicolai Soll, Bo Stork, Søren Kæseler Andersen, Louise Pil, Christian Stjernebjerg, Ole Graumann, Martin Bach Jensen

“…At follow-up, their scores had significantly increased for all POCUS applications, ranging from 80.9% to 92.6% of the maximum score. While completion of the educational elements varied between participants, all implemented POCUS in their daily practice during the educational program. …”
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Evaluating for learning and sustainability (ELS) framework: a realist synthesis by Marissa Bird, Maura MacPhee, James Shaw, Walter P. Wodchis, Lianne Jeffs, Tujuanna Austin, Frances Bruno, Balpreet Panesar, Élizabeth Côté Boileau, Robert J. Reid, Carolyn Steele Gray

“…Evaluation that catalyzes learning may contribute to health innovation implementation, refinement, and sustainability, however, there is little consensus as to why certain evaluations support learning, while others impede it. Methods Embedded in the implementation science literature, we conducted a realist synthesis to understand evaluative contextual factors and underlying mechanisms that best support health system learning and sustainable implementation of innovations. …”
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What’s Going On With Me and How Can I Better Manage My Health? The Potential of GPT-4 to Transform Discharge Letters Into Patient-Centered Letters to Enhance Patient Safety: Prospe... by Felix Eisinger, Friederike Holderried, Moritz Mahling, Christian Stegemann–Philipps, Anne Herrmann–Werner, Eric Nazarenus, Alessandra Sonanini, Martina Guthoff, Carsten Eickhoff, Martin Holderried

“…Further optimization of prompt engineering may help address this issue and improve the completeness of the transformation.…”
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The association of internet use and cognition among older adults: mediating roles of social networks and depressive symptoms by Xiuyuan Zhu, Zihan Ni, Xiaoying Zhu, Xiaoying Zhu, Yi Yang, Shiyu Xie, Xinguo Wang, Xiaoguang Yang

“…BackgroundTo explore the chain-mediated roles of social networks and depressive symptoms in the relationship between internet use and cognition among older adults.MethodsData were sourced from the 2018 China Longitudinal Aging Social Survey (CLASS). …”
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