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16421
Efficacy of different acupuncture-related therapies for tension-type headache: a systematic review and network meta-analysis
Published 2024-12-01“…Compared to herbal medicine (HM), both MA + WM (SMD = −2.37, 95% CI: −4.20 to −0.55) and MA alone (SMD = −1.00, 95% CI: −1.75 to −0.24) significantly alleviated pain intensity.ConclusionThis comprehensive analysis of 21 acupuncture and related therapies demonstrates that EA is the most effective in reducing headache frequency and shortening headache duration, while EA + CT and MA + WM are the optimal therapies for enhancing responder rate and reducing pain intensity, respectively. …”
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16422
How repeatable is PAPE effect: the impact of in-season isometric squat activation on countermovement jump performance enhancement in national level soccer players
Published 2025-05-01“…Given this variability, individually monitoring PAPE responsiveness may be beneficial for optimizing its application.…”
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16423
Molecular subtype of recurrent implantation failure reveals distinct endometrial etiology of female infertility
Published 2025-07-01“…Abstract Background Recurrent implantation failure (RIF) remains a significant barrier in assisted reproductive technology (ART), where multiple transfers of high-quality embryos fail to achieve pregnancy. While embryo-related factors have been extensively investigated, the contribution of endometrial dysfunction to RIF remains poorly characterized. …”
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16424
National and subnational burden of brain and central nervous system cancers in China and global from 1990 to 2021: results from the global burden of disease study 2021
Published 2025-07-01“…These updated findings provide critical insights for optimizing resource allocation and informing tailored interventions. …”
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16425
Impact of differentiated service delivery models on quality of life among people living with HIV in Uganda– a quasi-experimental study
Published 2025-06-01“…Methods Records of 1,000 PLHIV enrolled in a 10-year cohort at the Infectious Diseases Institute (IDI) clinic in Kampala, Uganda were retrospectively analyzed. …”
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16426
Efficacy and safety of oxaliplatin-based chemotherapy as first-line treatment in elderly patients with metastatic colorectal cancer: a meta-analysis
Published 2025-04-01“…Future trials must integrate biomarker-driven approaches (e.g., ctDNA monitoring, RAS/RAF stratification) to optimize therapeutic precision in aging populations.…”
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16427
Midazolam infusions for therapeutic management of pediatric refractory status epilepticus: a systematic review
Published 2025-04-01“…Two authors independently conducted screening, full-text review, and data extraction. All methods followed PRISMA reporting guidelines. A narrative data synthesis was performed due to data heterogeneity.Data extraction and synthesisNineteen studies (448 patients) proved eligible; 3 were randomized control trials, while 16 were non-randomized studies. …”
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16428
New mouse model based on adenocarcinoma 4T1 cells expressing HPV16 E6 and E7 applied to assess the efficacy of therapeutic and prophylactic E6/E7-based HPV16 vaccines
Published 2025-07-01“…E7 DNA was nonimmunogenic, while unstimulated T-cells produced TNF-α. In prophylactic settings, DNA-immunization with E6 and E7 suppressed formation of B2/H6 tumors. …”
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16429
Grass hay mixed-in creep feed or separately-fed differentially affects digestive development in pre- and post-weaning piglets
Published 2025-07-01“…Following weaning, GH nursery group had a reduced average daily gain (226 vs. 183 g, P < 0.001) during d 0–14, while this group showed compensatory growth afterwards (P = 0.056). …”
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16430
Effect of triple therapy on mortality and cardiovascular risk in patients with moderate to severe COPD: a meta-analysis of randomized controlled trials
Published 2025-07-01“…Abstract Background Chronic obstructive pulmonary disease (COPD), the third leading cause of global mortality, remains a significant challenge in long-term management. While dual bronchodilators (LAMA/LABA) and inhaled corticosteroid combination therapies (ICS/LABA) alleviate symptoms, patients continue to face elevated risks of all-cause mortality and cardiovascular events. …”
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16431
Risk factors and predictive thresholds for postoperative pleural effusion in children with neuroblastoma: a retrospective cohort study
Published 2025-07-01“…Perioperative inflammation modulation might represent a potential target for risk reduction, while maintaining adequate albumin levels and optimizing preoperative nutrition could be considered as supportive strategies. …”
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16432
Assessment of prostate cancer aggressiveness through the combined analysis of prostate MRI and 2.5D deep learning models
Published 2025-06-01“…Subsequently, radiomic features were extracted using pyradiomics tool, while deep learning features from each cross-section were derived using the Inception_v3 neural network. …”
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16433
Automatic segmentation and volume measurement of anterior visual pathway in brain 3D-T1WI using deep learning
Published 2025-04-01“…We aim to explore the feasibility of automatic AVP segmentation and volume measurement in brain T1-weighted imaging (T1WI) using the 3D UX-Net deep-learning model.MethodsClinical data and brain 3D T1WI from 119 adults were retrospectively collected. …”
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16434
Prevalence of CYP2C19 Variants in Patients with Cardiovascular Disease from the Yunnan-Guizhou Plateau in Southwestern China
Published 2025-05-01“…Here, differences in CYP2C19 alleles, genotypes, and phenotypes in patients with cardiovascular disease from the Yunnan-Guizhou Plateau were systematically surveyed to provide a reference for appropriate treatment approaches.Methods: The CYP2C19&ast;2, &ast;3, and &ast;17 variants were determined by RT-qPCR in 1934 patients with cardiovascular disease from 10 different areas of the Yunnan-Guizhou Plateau. …”
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16435
Efficacy and safety of zanubrutinib combined with chimeric antigen receptor T-cell therapy targeting CD19 in refractory or relapsed diffuse large B cell lymphoma: A retrospective a...
Published 2025-01-01“…Background: While chimeric antigen receptor T-cell (CAR T) therapy has shown promise in treating B-cell non-Hodgkin lymphoma, its efficacy is variable in patients with poor initial responses. …”
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16436
Developing a Machine Learning Model for Predicting 30-Day Major Adverse Cardiac and Cerebrovascular Events in Patients Undergoing Noncardiac Surgery: Retrospective Study
Published 2025-04-01“…Among 46,225 patients of the Seoul National University Bundang Hospital, MACCE occurred in 4.9% (2256/46,225), including myocardial infarction (907/46,225, 2%) and stroke (799/46,225, 1.7%), while in-hospital mortality was 0.9% (419/46,225). …”
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16437
Stress state calculation and potential failure risk identification of LNG storage tank inlet pipeline
Published 2025-05-01“…Identifying potential failure risks in the pipeline is essential for ensuring the safe operation of the LNG storage tank. MethodsTaking the inlet pipeline of a LNG terminal storage tank as an example, a numerical calculation model was developed for the temperature field of the pipeline. …”
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16438
The contribution of personalized video feedback to robotic partial nephrectomy training in realistic 3D tumor kidney models: design, production and implementation
Published 2025-07-01“…This study investigates the impact of 3D-printed renal models and video-based feedback on skill acquisition in robotic partial nephrectomy training.MethodsForty urology residents without prior robotic surgery experience participated in this study. …”
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16439
Rapid Initiation of Antiretroviral Therapy Suppresses T Cell Pathological Proliferation and Improves Immune Recovery in People Living with HIV
Published 2025-07-01“…Additionally, CD8⁺ T cells in the rapid ART group exhibited an increased presence of TN cells while showing a decreased proportion of PD-1/HLA-DR/CD38 high-expressing cells. …”
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16440
Trend analysis of pulmonary tuberculosis incidence among the elderly in Shanghai, 2014‒2023
Published 2025-03-01“…ObjectiveTo describe the epidemiological characteristics and trend of pulmonary tuberculosis among the elderly in Shanghai from 2014 to 2023, to estimate the incidence between 2024‒2025, so as to provide references for optimizing the prevention and control strategies of pulmonary tuberculosis for elderly in Shanghai.MethodsData of pulmonary tuberculosis patients aged ≥60 years in Shanghai registered in the Tuberculosis Registration and Management System of Chinese Center for Disease Control and Prevention from 2014 to 2023 was derived to describe the demographic characteristics of the elderly patients with pulmonary tuberculosis, and to calculate the reported incidence rate and annual percentage change (APC) of pulmonary tuberculosis. …”
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