Increased thrombin generation in kidney transplant recipients with donor-specific antibodies directed against human leukocyte antigens by Linda Lóczi, Linda Lóczi, Réka P. Szabó, Rita Orbán-Kálmándi, Rebeka Hodossy-Takács, Anikó Szilvási, Zoltán Szalai, Gábor Nagy, Péter Antal-Szalmás, Balázs Nemes, Zsuzsa Bagoly, Zsuzsa Bagoly, Zsuzsa Bagoly

“…Patients and methods. In this observational cohort study, 27 kidney transplant recipients with DSAs (DSA+ group) and 16 without DSAs (DSA– group) were enrolled. …”
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Safety and efficacy of oral edible bird’s nest supplementation: Anti-inflammatory and immunomodulatory benefits for Arabian race stallions during exercise by Khalid Obaid AL-Khaldi, Khalid Hamed Al-Ruzaiqi, Abdul Salam Babji, Seng Joe Lim, Mohammed Babatunde Sadiq, Nurhusien Yimer

“…Key objectives included assessing EBN’s impact on hepatic and renal function, hematological profiles, and sialic acid (SA) levels. Materials and Methods: Two experiments were conducted on 18 Arabian stallions. …”
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P-18 ANTI-HBC POSITIVITY IS AN INDEPENDENT PREDICTIVE FACTOR FOR HCC DEVELOPMENT AND SHOULD BE INCORPORATED TO THE HCC RISK SCORE PREDICTION MODEL IN ADVANCED FIBROSIS by Marcus Vinicius de Acevedo Garcia Gomes, Diogo Delgado Dotta, Manuella Andrade Oliveira Sobral, Isabela Bodaczny Taliberti, Alexandre Belucci Trazzi, Eduardo Pombo Nascimento, Betania da Silva Rocha, Patricia Momoyo Yoshimura Zitelli, Rosa Maria Nascimento Marcusso, Mario Guimaraes Pessoa

“…Patients / Materials and Methods: This is a retrospective, observational, descriptive and analytic study in a series of cases in which 365 HCV patients were evaluated. …”
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Safety Profile, Toxicokinetic, and Intestinal Absorption Differences of a Naturally-Derived Anti-Rheumatic Drug, Sinomenine Hydrochloride, in Normal and Arthritic Rats by Yini He, Hong Huang, Gejing Li, Ye Zhang, Junjie He, Ye Lin, Feichi Wu, Jianye Yan, Xiong Cai, Liang Liu

“…This study evaluated SH’s safety profile, TK parameters, and intestinal absorption differences in adjuvant–induced arthritis (AIA) and normal rats. <b>Methods</b>: Safety assessments determined median lethal doses (LD₅₀) in female Sprague Dawley rats. …”
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Proactive Therapeutic Drug MONiToring to Guide Suppressive Antibiotic Therapy with DALBAvaNcin ( &gt; 12 weeks) in Osteoarticular Infections (MONTALBANO) by C. Mariani, C. Mariani, M. Passerini, M. Passerini, L. Galli, L. Galli, A. Covizzi, M. Colaneri, M. Colaneri, M. Offer, M. Faenzi, S. Merli, S. Landonio, M. Fusi, M. Fusi, A. Dolci, A. Dolci, A. Gori, A. Gori, A. Gori, D. Cattaneo

“…This study evaluated the pharmacological efficacy of proactive therapeutic drug monitoring (TDM) to optimize dalbavancin administration. <strong>Methods</strong>: This single-center, retrospective study included adult OAI patients treated with <span class="inline-formula">≥4</span> doses of dalbavancin from July 2022 to October 2024. …”
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[Artículo traducido] Revisión sistemática sobre suplementos dietéticos en la prevención y/o tratamiento de la queratosis actínica y el campo de cancerización by A. Rodríguez-Luna, A. Zamarrón, C. Longo, G. Pellacani, K. Peris, P. Calzavara-Pinton, M.V. de Galvez, Y. Gilaberte, M. de Troya, Á. Juarranz, S. González

“…Methods: A review plan was pre-registered in the PROSPERO database (CRD42023485985). …”
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Systematic Review on Dietary Supplements in the Prevention and/or Treatment of Actinic Keratosis and Field Cancerization by A. Rodríguez-Luna, A. Zamarrón, C. Longo, G. Pellacani, K. Peris, P. Calzavara-Pinton, M.V. de Galvez, Y. Gilaberte, M. de Troya, Á. Juarranz, S. González

“…Methods: A review plan was pre-registered in the PROSPERO database (CRD42023485985). …”
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Impact of COVID-19 on Corporate Cash Holdings and Speed of Adjustment by Abbas Aflatooni, Mohammad Khatiri, Farzad Eivani

“…The analysis used observations from 159 firms from 2008 to 2022, applying Generalized Least Squares (GLS) regression and the system Generalized Method of Moments (system-GMM) while controlling for industry and year effects. …”
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Microwave-dried black soldier fly larvae enhance growth, intestinal health, and humoral imm by Osfar Sjofjan, Ari Ardiantoro, Inaayah Novitri Cahyawati, Amalia Iffah Jihana, Muhammad Halim Natsir, Yuli Frita Nuningtyas, Danung Nur Adli

“…The high lauric acid content and bioactive compounds in MDBSFM may contribute to these beneficial effects. While IGF-1 upregulation trends warrant further molecular investigation, MDBSFM offers a viable alternative to antibiotic growth promoters in poultry diets. …”
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Intravenous immunoglobulin therapy: usage patterns and response to treatment in Qatar over ten years by Salma A. Taha, Sherin Thalappil, Ramzy M. Ali, Haajra Fatima, Asaad Omer A. Imameldin, Sami Aqel, Ahmed M. Abdelaal, Timo Siepmann, Timo Siepmann, Jessica Barlinn, Jessica Barlinn, Maryam A. Al-Nesf

“…Further research is warranted to inform local guidelines and optimize IVIg therapy outcomes.…”
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Tracheostomy Practice in the Italian Intensive Care Units: A Point-Prevalence Survey by Raffaele Merola, Maria Vargas, Filippo Sanfilippo, Marco Vergano, Giovanni Mistraletti, Luigi Vetrugno, Gennaro De Pascale, Elena Giovanna Bignami, Giuseppe Servillo, Denise Battaglini

“…<i>Materials and Methods</i>: We conducted an observational, cross-sectional, point-prevalence survey across eight ICUs in Italy. …”
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Comparative cardiovascular outcomes and safety of hypoglycemic drug classes in patients with type 2 diabetes and hypertension: a multicenter cohort analysis by Zhiyuan Wei, Wanqian Xu, Yu Wang, Yu Tian, Zhongmin Wang, Shenqi Jing, Weina Liu, Sipeng Shen, Chenlong Qin, Xin Zhang, Jingsong Li, Yun Liu

“…For safety outcomes, DPP4is were associated with a reduced risk of chronic kidney disease, while insulin use was associated with reduced risks of inflammatory polyarthritis and insomnia. …”
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Erector spinae plane block versus transversus abdominis plane block with rectus sheath block for postoperative analgesia in laparoscopic hepatectomy: a randomized clinical trial by Mengke Liu, Xuan Mo, Ruonan Zhan, Han Wang, Yangxi Zhao, Yi Zhang

“…Methods Sixty patients scheduled for laparoscopic hepatectomy were randomly divided into two groups: E group received ultrasound-guided ESPB, while the TR group received subcostal TAPB with RSB. …”
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Evaluation of Inflammatory Markers and Clinical Outcomes in COVID-19 Patients with Concurrent <i>Clostridioides difficile</i> Infection: A Comparative Cohort Analysis by Flavia Ignuta, Adrian Vlad, Teodor Cerbulescu, Stana Loredana, Felix Bratosin, Ovidiu Rosca, Lavinia Stelea, Daciana Nistor

“…Background and Objectives: Co-infection with <i>Clostridioides difficile</i> (<i>C. difficile</i>) in COVID-19 patients has emerged as a clinical challenge associated with increased morbidity and mortality. While both infections elicit systemic inflammation, the interplay between inflammatory markers, disease severity, and outcomes in patients with COVID-19 and concurrent <i>C. difficile</i> infection remains poorly characterized. …”
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Fosaprepitant Use as an Antiemetic to Prevent Postoperative Nausea and Vomiting in Pediatric Spinal Fusion Patients May Be Associated With More Rapid Transition to Oral Pain Medica... by Jennifer Busse, Aaron Louie, Jennifer Crotty, Albert Lin, Zarema Muratova, Matan Malka, Ritt Givens, Benjamin Roye, Michael Vitale, William Schechter

“…Future studies are needed to elucidate the optimal dose and timing needed to treat PONV in pediatrics. …”
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Preferences for HIV pre‐exposure prophylaxis among men who have sex with men and trans women in 15 countries and territories in Asia and Australia: a discrete choice experiment by Warittha Tieosapjaroen, Benjamin R. Bavinton, Heather‐Marie A. Schmidt, Curtis Chan, Kim E. Green, Nittaya Phanuphak, Midnight Poonkasetwattana, Nicky S. Suwandi, Doug Fraser, Hua Boonyapisomparn, Michael Cassell, Lei Zhang, Weiming Tang, Jason J. Ong

“…Compared to those at lower risk of HIV, free access was more preferred by MSM at a higher risk of HIV, while telehealth was more preferred by TGW at a substantial risk of HIV. …”
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Essential newborn care practices at health facilities and homes in Ethiopia: a cross-sectional study by Tadesse Guadu, Kassahun Alemu, Joanna Schellenberg, Della Berhanu, Seblewengel Lemma, Atkure Defar, Theodros Getachew, Girum Taye, Solomon Shiferaw, Zewditu Abdissa, Amare Tariku, Meseret Zelalem, Lars Åke Persson

“…Thermal care, cord care, and provision of vaccines at birth were relatively more common in Addis Ababa, while first-hour breastfeeding initiation was higher in the Oromia region. …”
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Synthesis and Evaluation of ^99mTc(CO)₃ Complexes with Ciprofloxacin Dithiocarbamate for Infection Imaging by Afroditi Papasavva, Nektarios N. Pirmettis, Antonio Shegani, Eleni Papadopoulou, Christos Kiritsis, Maria Georgoutsou-Spyridonos, Dimitrios C. Mastellos, Aristeidis Chiotellis, Patricia Kyprianidou, Maria Pelecanou, Minas Papadopoulos, Ioannis Pirmettis

“…Future studies will focus on optimizing molecular weight, lipophilicity, and stability to further enhance the diagnostic specificity and clinical utility of these radiopharmaceuticals.…”
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A Prospective Analysis of the Burden of Multi-Drug-Resistant Pathogens in Acute Appendicitis and Their Implication for Clinical Management by Faruk Koca, Sara Fatima Faqar-Uz-Zaman, Claudia Reinheimer, Michael Hogardt, Volkhard A. J. Kempf, Paul Ziegler, Andreas A. Schnitzbauer, Armin Wiegering, Wolf Otto Bechstein, Patrizia Malkomes

“…However, prospective data on the microbial spectrum and its clinical impact remain limited. <b>Methods</b>: Adults with acute appendicitis undergoing surgery between April 2022 and July 2023 were prospectively enrolled at a single university-affiliated institution. …”
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Analysis of Disease Burden and Attributable Risk Factors of Early-onset Female Breast Cancer in China and Globally from 1990 to 2021 by HUANG Danqi, YANG Min, XIONG Wei, LIU Jingyi, CHEN Wanqing, ZHAI Jingbo, LI Jiang

“…ObjectiveTo analyze the disease burden, temporal trends, and attributable risk factors of early-onset female breast cancer (EOBC) in China and globally from 1990 to 2021.MethodsData on the absolute numbers and crude rates of incidence, mortality, and disability-adjusted life years (DALYs) for EOBC (diagnosis age < 50 years) in China and globally were extracted from the Global Burden of Disease (GBD) 2021 database. …”
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