Evaluation of three mechanisms of action (SGLT2 inhibitors, GLP-1 receptor agonists, and sulfonylureas) in treating type 2 diabetes with heart failure: a systematic review and netw... by Huize Gao, Qian Wei, Anqi Zou, Keying Yu, Da Song, Jian Li, Huize Han, Aidong Liu

“…GLIM (SMD = –0.64, 95% CI: –1.12 to –0.17) showed the strongest effect on lowering HbA1c, while DAPA (SMD = 0.34, 95% CI: –0.97 to 1.65) was the top-ranked agent for improving LVEF. …”
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Phase transformation and flow simulation of weld pools at the crack tips of elbows under pulsed current by Si ZHANG, Mingjiang ZHOU, Yuheng LIANG, Biwei FU

“…Consequently, a pulse interval greater than 0.008 seconds was identified as optimal to prevent adverse effects on the weld pool area during subsequent pulses, thereby enhancing repair performance. …”
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Distinct Roles of HHLA2 and PD-L1 in the Immune Cell and Prognosis of Hepatocellular Carcinoma by Wang CH, Chen SL, Yang X, Wu T, Liu LL, Yun JP

“…Hematoxylin and eosin (H&E) staining was utilized to quantify TILs (percentage/area), while IHC was used to measure the densities of CD3+, CD4+, and CD8+ TILs (cells/mm²).Results: HHLA2 and PD-L1 exhibited similar positivity rates. …”
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Evaluation of Self-Regulating Doped Ferrite Nanoparticles with Glucose, Chitosan, and Poly-Ethylene Glycol Coatings for Hyperthermia and Dual Imaging by Negri A, Conti A, Milan E, Forlin E, Gherlinzoni F, Morana G, Gottardi M, Matteazzi P, Speghini A, Bongers A, Marzola P

“…GM55, in particular, offers superior MFH efficacy and cellular uptake, while CM55 and PM55 may present unique advantages for alternative biomedical applications. …”
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Chronic disease comorbidities among middle-aged and elderly Chinese population with different depression levels: a network analysis on 2018 CHARLS data by Qiaofeng LI, Yilong YAN, Yuehan HE, Yongtai LI, Guowu DING

“…ObjectiveTo understand the chronic disease comorbidities among middle-aged and elderly Chinese population with different depression levels and provide a scientific basis for optimizing depression screening and chronic disease prevention and treatment. …”
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Improving AI-Based Clinical Decision Support Systems and Their Integration Into Care From the Perspective of Experts: Interview Study Among Different Stakeholders by Godwin Denk Giebel, Pascal Raszke, Hartmuth Nowak, Lars Palmowski, Michael Adamzik, Philipp Heinz, Marianne Tokic, Nina Timmesfeld, Frank Martin Brunkhorst, Jürgen Wasem, Nikola Blase

“… BackgroundArtificial intelligence (AI)–based systems are receiving increasing attention in the health care sector. While the use of AI is well advanced in some medical applications, such as image recognition, it is still in its infancy in others, such as clinical decision support systems (CDSS). …”
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A Monocyte-Driven Prognostic Model for Multiple Myeloma: Multi-Omics and Machine Learning Insights by Xie L, Gao M, Tan S, Zhou Y, Liu J, Wang L, Li X

“…Results indicated that low-risk patients are more likely to benefit from immunotherapy, while a high MGPS score reflects cellular functional impairment.Conclusion: Our findings reveal a complex interplay between immune cells and MM. …”
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Prognostic value of albumin-corrected anion gap in critically ill patients with sepsis-associated liver injury: a retrospective study by Jianjun Wang, Yonghai Peng, Zhaohui Hu, Xi Chen, Sirui Chen, Pei Yang, Xintao Zeng, Decai Wang

“…We explored the association between ACAG and patient prognosis in individuals diagnosed with SALI. Methods Data from patients with SALI admitted to the intensive care unit (ICU) between 2008 and 2022 were retrospectively analyzed. …”
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A real-world disproportionality analysis of FDA adverse event reporting system (FAERS) events for lecanemab by Linlin Yan, Linhai Zhang, Zucai Xu, Zhong Luo

“…A biweekly 10 mg/kg was identified as the optimal therapeutic dosage. ARIA emerged as frequent treatment-related AEs, with APOEɛ4 carriers demonstrating heightened susceptibility. …”
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Advancements in Hyaluronic Acid Effect in Alveolar Ridge Preservation: A Narrative Review by Paul Andrei Nistor, Andreea Cândea, Iulia Cristina Micu, Andrada Soancă, Carmen Silvia Caloian, Alina Bârdea, Alexandra Roman

“…The knowledge of HYA effects facilitates the selection of personalized ARP approaches tailored to optimize outcomes for subsequent interventions.…”
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SARS-CoV-2 Variant-Specific Antibodies in Vaccinated Inflammatory Bowel Disease Patients by Eva Ulla Lorentzen, Richard Vollenberg, Rieke Neddermeyer, Michael Schoefbaenker, Eike R. Hrincius, Stephan Ludwig, Phil-Robin Tepasse, Joachim Ewald Kuehn

“…Anti-TNF-treated individuals with antibody levels below the optimized CMIA threshold should be considered for early booster vaccination and/or close immunological monitoring.…”
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Geriatric Nutritional Risk Index (GNRI) and Prognostic Nutritional Index (PNI) Before Treatment as the Predictive Indicators for Bone Metastasis in Prostate Cancer Patients by Chen L, Rao H, Chen N, Li R, Chen D, Jiang H

“…The levels of GNRI and PNI in patients with bone metastasis were significantly lower than those without, while NAR, PIV, SII, and SIRI were not statistically significant. …”
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Peer2Me - impact of peer support on self-efficacy in young adult cancer survivors (YA-CS): findings from a comprehensive cohort design by Hannah Brock, Sarah Dwinger, Michael Friedrich, Annekathrin Sender, Kristina Geue, Anja Mehnert-Theuerkauf, Corinna Bergelt, Diana Richter

“…Although interest in peer mentoring was high, the intervention showed no measurable benefit in comparison with standard care. While the need for support was evident, further research is required to optimize peer interventions for this group. …”
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Lytic bacteriophages targeting multidrug-resistant Pseudomonas aeruginosa in Moschus berezovskii: isolation, characterization, and therapeutic efficacy against bacteremia by Qingxia Hu, Yanjie Zhang, Ni Lv, Yahao Kang, Saba Nasir, Ruiqing Wang, Jiahao Qu, Jiadeng Jiang, Xiao Li, Xinglong Wang

“…The safety and practicality of the two phages were analyzed through methods such as biological characteristic assessment, whole genome sequencing analysis, and animal experiments. …”
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Twice against thrice-weekly hemodialysis (TATH): a multicenter nonrandomized trial by Mabel Aoun, Serge Finianos, Chadia Beaini, Ghassan Sleilaty, Rita Ghaleb, Nicole Nourie, Sami Kais, Joseph El Hajal, Rachad Alameddine, Celine Boueri, Balsam El Ghoul, Sandy Zeidan, Hiba Azar, Antoine Dfouni, Jenny Hawi, Zeina Mechref, Valerie Hage, Dania Chelala

“…Abstract Background The optimal frequency of maintenance hemodialysis remains a subject of debate. …”
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Impacts of the hydrochemical characteristics of coal seam water on the structures and metabolic functions of microbial communities by Gaohao WANG, Shengjie DUAN, Bei WANG, Guobin NIU, Yongping LIANG, Feilong YU, Kai MA, Weizhong ZHAO

“…The results of this study reveal the mechanisms behind the impacts of the hydrochemical characteristics of coal seam water on microbial communities while also laying a scientific basis for optimizing the formulation of bio-fracturing fluids in CBM bioengineering. …”
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Comparison of four MRI diffusion models to differentiate benign from metastatic retropharyngeal lymph nodes by Jun Liu, Li Hua, Fei Wang, Ming Chen, Yinan Sun, Zhi Hu, Luqing Shu, Andong He, Mengxiao Liu, Qing Yang, Juan Zhu, Yinfeng Qian

“…Benign RLNs exhibited higher ADC, DDCSEM, DFROC, and DCTRW, while metastatic RLNs had higher αSEM, βFROC, μFROC, and βCTRW. …”
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Integrative habitat analysis and multi-instance deep learning for predictive model of PD-1/PD-L1 immunotherapy efficacy in NSCLC patients: a dual-center retrospective study by Xiaoxiao Huang, Xiaoxin Huang, Yurun Xie, Kui Wang, Housheng Bai, Ruiling Ning, Xiqi Zhu, Deyou Huang, Guanqiao Jin

“…This dual-center study aimed to integrate habitat radiomics and multi-instance deep learning to predict durable clinical benefits from immunotherapy. Methods We retrospectively collected 590 NSCLC patients from two medical centers who received PD-1/PD-L1 inhibitor immunotherapy. …”
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Atrial fibrillation and chronic kidney disease: main clinical characteristics of patients in selected subjects of the Russian Federation by M. A. Druzhilov, T. Yu. Kuznetsova, O. Yu. Druzhilova, U. D. Arustamova, D. V. Gavrilov, A. V. Gusev

“…Patients with AF and eGFR <60 ml/min/1,73 m2 are charac­terized by greater comorbidity, a higher incidence of IS, MI and ICH compared with patients with AF and eGFR ≥60 ml/min/1,73 m2, while ACT prescription rate as of 2016-2019 in some Russian subjects was unsatisfactory. …”
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Compact Multi-Channel Long-Wave Wideband Direction-Finding System and Direction-Finding Analysis for Different Modulation Signals by Hangyu Lu, Shun Wang, Xin Xu, Yicai Ji, Xiaojun Liu

“…This paper presents an optimized long-wave (10–300 kHz) wideband direction-finding system for scientific research. …”
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