Evaluating and Forecasting the Probability of Lightning Occurrence in Rasht City by Afsaneh Ghasemi, Jamil Amanollahi

“…The main purpose of this study was to use recorded ground data from the occurrence and non-occurrence of lightning (binary data) and the effect of related meteorological parameters (temperature, relative humidity, cloudy, wind speed, wind direction, pressure air and previous day's lightning) to estimate the probability of lightning occurrence in future using data mining (trees and neural network models) and evaluate and determine the optimal model to reduce future damage. 2-Materials and Methods In this study, binary data of lightning and atmospheric parameters (temperature, relative humidity, cloudy, wind speed, wind direction, pressure air and previous day's lightning) were obtained from Rasht Meteorological Station during the years 2012-2018. …”
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Integration of Network Pharmacology, Transcriptomics, and Metabolomics Strategies to Uncover the Mechanism of Chaihuang Qingfu Pill in Treating Sepsis-Induced Liver Injury by Zhang C, Chen F, Jiang Y, Deng J, Yan X, Yin X, Su B, Liu W

“…This study aims to systematically investigate the molecular basis of CHQF in the mitigation of sepsis-associated liver damage.Purpose: To explore the mechanism of CHQF for the treatment of sepsis-induced liver injury.Methods: A sepsis mouse model was established via cecal ligation and puncture (CLP). …”
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The impact of early vs. delayed surgery on outcomes in cervical spinal cord injury without fracture or dislocation by Sirui Xiao, Hui Yan, Beixi Bao, Yuxuan Wu, Xiaokang Cheng, Chunyang Xu, Jiaguang Tang

“…ObjectiveThis study aims to retrospectively analyze 104 patients diagnosed with cervical spinal cord injury without fracture or dislocation (CSCIwoFD) who underwent surgical treatment, in order to compare the effects of early vs. delayed surgical intervention on neurological functional recovery.MethodsPatients diagnosed with CSCIwoFD and treated surgically at our institution between August 2020 and January 2023 were retrospectively reviewed. …”
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UMI-77 targets MCL-1 to activate mitophagy and ameliorate periodontitis in mice by Dalei Sun, Shu Ouyang, Xiaoxuan Xu, Jingjing Yan, Heqian Wang, Chenkai Lan, Wubin Ouyang, Liangjun Zhong, Jun Lin

“…Western blot confirmed downregulation of MCL-1 expression to near-normal levels in Group Ba, while TEM detected autolysosomes in both Group Ba and Group Ca, indicating mitophagy activation. …”
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A multi-dimensional performance evaluation of large language models in dental implantology: comparison of ChatGPT, DeepSeek, Grok, Gemini and Qwen across diverse clinical scenarios by Xing Wu, Guofei Cai, Bin Guo, Leizi Ma, Siqi Shao, Jun Yu, Yuchen Zheng, Linhong Wang, Fan Yang

“…Mixed-effects models showed Gemini-2.0-flash-thinking superiority over ChatGPT-o3-mini, while Qwen2.5-max exhibited a decline in performance. …”
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Risk factors of low bone mass in young patients with transfusion-dependent beta-thalassemia by Wei Zhang, Wei Zhang, Rongrong Liu, Rongrong Liu, Rongrong Liu, Siping He, Jihua Huang, Liting Wu, Cuifeng Huang, Yuzhen Liang, Yongrong Lai, Yongrong Lai, Yongrong Lai

“…ObjectiveTo determine the prevalence of low bone mass and associated risk factors among children and adolescents suffering from transfusion-dependent beta-thalassemia (TDT).MethodsIn this study, a total of 389 children and adolescents with TDT (236 males and 153 females), treated between January 2015 and December 2024 in the Department of Hematology at the First Affiliated Hospital of Guangxi Medical University, were selected. …”
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Conservation of Verbascum sinaiticum Benth using innovative tissue culture technique and DNA barcoding by Mohamed Abdel-Shakur Ali, Nora Rabee Gowda, Mai A. Allam, Sayed A. Fayed

“…We have devised flexible methods for large-scale micropropagation that offer a sustainable and quick production strategy, even in the face of resource constraints. …”
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Development and external validation of machine learning models for the early prediction of malnutrition in critically ill patients: a prospective observational study by Yi Liu, Yehua Xu, Lixia Guo, Zhongbin Chen, Xueqin Xia, Feng Chen, Li Tang, Hua Jiang, Caixia Xie

“…Hyperparameters were optimized via 5-fold cross-validation on the training set, eliminating the need for a separate validation set while ensuring internal validation. …”
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A nomogram for predicting early bacterial infection after liver transplantation: a retrospective study by Jie Yu, Jie Yu, Jichang Jiang, Jichang Jiang, Caili Fan, Caili Fan, Jinlong Huo, Jinlong Huo, Tingting Luo, Tingting Luo, Lijin Zhao, Lijin Zhao

“…It can effectively identify the high-risk group for bacterial infection in the early postoperative period after liver transplantation, while simultaneously helping the transplant team dynamically monitor the key indicators and optimize perioperative management.…”
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Cervical cerclage for prevention of preterm birth and adverse perinatal outcome in twin pregnancies with short cervical length or cervical dilatation: A systematic review and meta-... by Francesco D'Antonio, Nashwa Eltaweel, Smriti Prasad, Maria Elena Flacco, Lamberto Manzoli, Asma Khalil

“…<h4>Background</h4>The optimal approach to prevent preterm birth (PTB) in twins has not been fully established yet. …”
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An assessment of the level of knowledge about diabetes mellitus among diabetic patients in a primary healthcare setting by Lushendran M. Moodley, Viren Rambiritch

“…Section A investigated basic patient history (demographics and disease state), while section B was a basic knowledge test on diabetes mellitus. …”
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Impact of Obesity on the Long-Term Outcomes of Advanced Therapies in IBD: A Real-World Study in Taiwan by Hsu WC, Lin SH, Kuo CJ, Chiu HY, Chen CM, Su MY, Chiu CT, Chang CW, Huang TY, Pan YB, Le PH

“…Future studies should explore optimal therapies for obese IBD patients.Keywords: inflammatory bowel disease, advanced therapies, drug persistence, overweight, obesity…”
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Cone-beam CT measurement of root canal diameter and taper for mandibular first molar by LI Wenmiao, XING Li, PAN Yingyu, HUANG Ying, YANG Guofang, LIU Deda

“…Objective·To analyze the root canal diameter and taper of mandibular first molars using cone-beam CT (CBCT), investigate age-related changes in these parameters, and propose optimized clinical protocols for root canal preparation.Methods·From October 2022 to October 2023, CBCT images of 240 healthy mandibular first molars (120 three-canal type cases and 120 four-canal type cases) were collected from patients aged 20‒59 years at the Stomatology Center, Haikou Affiliated Hospital of Central South University Xiangya School of Medicine. …”
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Effectiveness of Telemedicine Interventions on Motor and Nonmotor Outcomes in Parkinson Disease: Systematic Review and Network Meta-Analysis by Jiejie Dou, Junyu Wang, Xianqi Gao, Guotuan Wang, Ying Bai, Yixin Liang, Kunyi Yang, Yong Yang, Lin Zhang

“…ConclusionsTelemedicine is effective for improving motor and nonmotor outcomes in PD. e-Exercise is optimal for motor function and physical performance, while e-Cognitive is most effective for psychological and cognitive challenges. …”
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Novel triple-target panels utilizing methylation-sensitive restriction enzyme-based quantitative PCR for detecting advanced cervical precancers and cancers among high-risk HPV-posi... by Shimin Chen, Hongshuang Dai, Shangying Hu, Tangjie Gao, Ming Chen, Xinghua Zhou, Lizhong Dai, Xuelian Zhao, Fanghui Zhao

“…Abstract Background Optimal triage option for high-risk HPV-positive (hrHPV) women remains uncertain. …”
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Molecular subtype of recurrent implantation failure reveals distinct endometrial etiology of female infertility by Jing Yang, Lingtao Yang, Ying Zhou, Fengyang Cao, Hongkun Fang, Huan Ma, Jun Ren, Chunyu Huang, Lianghui Diao, Qiyuan Li, Qionghua Chen

“…Abstract Background Recurrent implantation failure (RIF) remains a significant barrier in assisted reproductive technology (ART), where multiple transfers of high-quality embryos fail to achieve pregnancy. While embryo-related factors have been extensively investigated, the contribution of endometrial dysfunction to RIF remains poorly characterized. …”
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National and subnational burden of brain and central nervous system cancers in China and global from 1990 to 2021: results from the global burden of disease study 2021 by Shifan Tu, Xiaolu Huang, Xiaoxuan Fan, Yi Zhang, Lan Huang, Kai Li, Xinyue Wang, Yunpeng Gao, Xiaoping Zhao, Zhaoqun Feng

“…These updated findings provide critical insights for optimizing resource allocation and informing tailored interventions. …”
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New mouse model based on adenocarcinoma 4T1 cells expressing HPV16 E6 and E7 applied to assess the efficacy of therapeutic and prophylactic E6/E7-based HPV16 vaccines by Juris Jansons, Daria Avdoshina, Alesja Dudorova, Elena Royo Rubio, Liba Sokolovska, Dmitry Perminov, Ilze Lindenberga, Hannes Nicolai, Svetlana Gebrila, Sona Chowdhury, Dace Skrastina, Jurijs Nazarovs, Joel M. Palefsky, Maria Isaguliants

“…E7 DNA was nonimmunogenic, while unstimulated T-cells produced TNF-α. In prophylactic settings, DNA-immunization with E6 and E7 suppressed formation of B2/H6 tumors. …”
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Grass hay mixed-in creep feed or separately-fed differentially affects digestive development in pre- and post-weaning piglets by Renjie Yao, Tetske G. Hulshof, Hubèrt M. J. van Hees, An Cools, Mattijs Merckx, Dominiek Maes, Geert P. J. Janssens

“…Following weaning, GH nursery group had a reduced average daily gain (226 vs. 183 g, P < 0.001) during d 0–14, while this group showed compensatory growth afterwards (P = 0.056). …”
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Effect of triple therapy on mortality and cardiovascular risk in patients with moderate to severe COPD: a meta-analysis of randomized controlled trials by Yubing Li, Jun Li, Hongxia Yang, Yong Zhang

“…Abstract Background Chronic obstructive pulmonary disease (COPD), the third leading cause of global mortality, remains a significant challenge in long-term management. While dual bronchodilators (LAMA/LABA) and inhaled corticosteroid combination therapies (ICS/LABA) alleviate symptoms, patients continue to face elevated risks of all-cause mortality and cardiovascular events. …”
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