Recent advances of epilepsy associated with neurofibromatosis type 1 by Ying Ren, Ying Ren, Wandong Hu, Wandong Hu, Song Su, Song Su, Qi Zhang, Qi Zhang, Wenchao Zhang, Wenchao Zhang, Hongwei Zhang, Hongwei Zhang, Guangyu Wang, Guangyu Wang

“…Early identification and personalized therapy are critical for optimal management of this patient population. This review aims to synthesize published literature on the disease, thereby providing a comprehensive, detailed, and updated overview of its entire clinical spectrum.MethodsWe conducted a comprehensive literature search in PubMed, China National Knowledge Infrastructure, and Chinese Medical Association Journal Full-text Database for original research articles with available full-text manuscripts in English or Chinese, with a publication cutoff date of March 1, 2025. …”
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Prompt Framework for Extracting Scale-Related Knowledge Entities from Chinese Medical Literature: Development and Evaluation Study by Jie Hao, Zhenli Chen, Qinglong Peng, Liang Zhao, Wanqing Zhao, Shan Cong, Junlian Li, Jiao Li, Qing Qian, Haixia Sun

“…MethodsMedScaleNER incorporates demonstration retrieval within in-context learning, chain-of-thought prompting, and self-verification strategies to improve performance. …”
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Biomechanical stability and stress distribution before talus prosthesis design: effects of ligament removal and cartilage overlay thickness using finite element analysis by Gang Zeng, Yujun Sun, Min Liang, Wenzhou Liu, Yanbo Chen, Jionglin Wu, Jiayuan Zheng, Taolue Zhou, Huiying Zhao, Weidong Song, Yue Ding

“…Adjacent joint arthritis is the most common complication after total talar replacement (TTR). While intervention is rarely required, varying degrees of postoperative degenerative changes have been reported in surrounding joints. …”
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Predicting the Likelihood of Operational Risk Occurrence in the Banking Industry Using Machine Learning Algorithms by Hamed Naderi, Mohammad Ali Rastegar Sorkhe, Bakhtiar Ostadi, Mehrdad Kargari

“…Specifically, the RF algorithm achieved an accuracy of 0.9690, while the SVM algorithm attained an accuracy of 0.9587 in State 1, making them the most effective models in this setting. …”
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Purification and Functional Characterization of a New Endoglucanase from <i>Pleurotus djamor</i> PLO13 Produced by Solid-State Fermentation of Agro-Industrial Waste by Monizy da Costa Silva, Ricardo Bezerra Costa, Marta Maria Oliveira dos Santos Gomes, Josiel Santos do Nascimento, Andreza Heloiza da Silva Gonçalves, Jéssica Alves Nunes, Marta Angelo dos Santos, Francis Soares Gomes, José Maria Rodrigues da Luz, Luciano Aparecido Meireles Grillo, Hugo Juarez Vieira Pereira

“…The purified enzyme exhibited stability across a broad pH range and thermostability, with optimal activity at pH 5.0 and 50 °C. Furthermore, the enzyme was activated by EDTA, Mn²⁺, and Ca²⁺, while being inhibited by Mg²⁺. …”
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Role of High Serum Tenascin C Levels as Potential Biomarker of Persistent Inflammation in Patients with Ankylosing Spondylitis Despite Treatment with cs-DMARDS or Anti-TNF Agents by Alejandro Martelli-Garcia, Yussef Esparza-Guerrero, Heriberto Jacobo-Cuevas, Ana Miriam Saldaña-Cruz, Norma Guadalupe Gonzalez-Montoya, Cesar Arturo Nava-Valdivia, Eli Efrain Gomez-Ramirez, Maria Luisa Vazquez-Villegas, Juan Manuel Ponce-Guarneros, Melissa Ramirez-Villafaña, Norma Alejandra Rodriguez-Jimenez, Alberto Daniel Rocha-Muñoz, Ernesto German Cardona-Muñoz, Jaime Morales-Romero, Laura Gonzalez-Lopez, Jorge Ivan Gamez-Nava

“…Response was assessed with the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI); scores ≥ 4 indicate persistent disease activity, while scores < 4 indicate inactive disease. Serum TNC levels, C-reactive protein (CRP) levels, and Erythrocyte Sedimentation Rate (ESR) were determined through the ELISA technique, nephelometry, and the Westergren method, respectively. …”
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Comparative efficacy of acupuncture for chronic low back pain: A network meta-analysis by Feng Gao, Dongming Jia, Shengxia Xue

“…Background: Chronic non-specific low back pain (CNSLBP) is a globally prevalent condition that significantly impairs quality of life and imposes a substantial burden on healthcare systems. While acupuncture is widely recognized for its therapeutic benefits, a comprehensive comparison of its efficacy across different modalities remains lacking. …”
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Size-dependent aggregation of erythrocytes by low molecular weight hyaluronic acids of different sizes: bioactivity and quality control potential by Xinyue Ma, Xiao Wang, XiaoXiao Jia, Jessica H. Hui, Joshua H. Shofaro, Ran Tao, Mizhou Matthew Hui

“…LMW-HA samples were applied at varying concentrations to measure their binding affinity to erythrocytes, while CD44 antibodies were used to assess receptor involvement. …”
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Psychometric properties of the Persian version of the training needs assessment for critical care nurses by Amir Jalali, Mostafa Bafandeh Zendeh, Azam Sharifi, Amirhossein Naghibzadeh, Leila Moradi, Jalal Karimi, Nazanin Mardani Taghvostani, Khalil Moradi

“…Abstract Background Identifying the training needs of critical care nurses is crucial for enhancing their performance and optimizing patient outcomes. This process requires a comprehensive understanding of their specific knowledge gaps and skill deficiencies. …”
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Preliminary exploration of finite element biomechanical preoperative planning for complex tibial plateau fractures by Zhi Xu, Yuwan Li, Shoujin Tian, Xing Xu, Hao Zhou, Min Yang

“…Abstract The aim of this study was to compare the clinical outcomes, biomechanical performance, and cost-effectiveness of finite element planning (FEP) with those of traditional (Trad) methods in the treatment of complex tibial plateau fractures in middle-aged and elderly patients to ultimately optimize treatment protocols, improve surgical efficiency, and reduce the economic burden on patients. …”
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From access to reserve: antimicrobial resistance among etiological agents of central line-associated bloodstream infections in the view of WHO’s AWaRe antimicrobial spectrum by Anand, Gargee, Lahariya, Rijhul, Priyadarshi, Ketan, Sarfraz, Asim

“…Pseudomonas aeruginosa showed a drastic drop in Watch-category susceptibility, from 44.5% in 2021 to 0% in 2023, while Reserve-agents remained effective. These results underline the growing reliance on Reserve antimicrobials and the diminishing effectiveness of first-line agents. …”
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Clinical and epidemiologic characteristics of dengue and other etiologic agents among patients with acute febrile illness, Puerto Rico, 2012-2015. by Kay M Tomashek, Olga D Lorenzi, Doris A Andújar-Pérez, Brenda C Torres-Velásquez, Elizabeth A Hunsperger, Jorge Luis Munoz-Jordan, Janice Perez-Padilla, Aidsa Rivera, Gladys E Gonzalez-Zeno, Tyler M Sharp, Renee L Galloway, Mindy Glass Elrod, Demetrius L Mathis, M Steven Oberste, W Allan Nix, Elizabeth Henderson, Jennifer McQuiston, Joseph Singleton, Cecilia Kato, Carlos García Gubern, William Santiago-Rivera, Jesús Cruz-Correa, Robert Muns-Sosa, Juan D Ortiz-Rivera, Gerson Jiménez, Ivonne E Galarza, Kalanthe Horiuchi, Harold S Margolis, Luisa I Alvarado

“…Prospective AFI studies provide a methodology to describe the syndrome by age and etiology, findings that can be used to develop case definitions and multiplexed diagnostics to optimize management. We conducted a 3-year prospective AFI study in Puerto Rico. …”
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Association of dietary quality, biological aging, progression and mortality of cardiovascular-kidney-metabolic syndrome: insights from mediation and machine learning approaches by Junfeng Ge, Lin Zhu, Sijie Jiang, Wenyan Li, Rongzhan Lin, Jun Wu, Fengying Dong, Jin Deng, Yi Lu

“…Abstract Background To investigate the association between the Dietary Inflammatory Index (DII), biological aging, and the staging and mortality of cardiovascular-kidney-metabolic (CKM) syndrome. Methods Data of 7,918 participants were derived from the National Health and Nutrition Examination Survey 2005–2018. …”
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Abstract 059: The Tenzing‐Dotter Technique for Endovascular Management of Atherosclerotic Cervical ICA Tandem Large Vessel Occlusions by Joey D English

“…Seven patients were treated with Tenzing 7 paired with a large bore catheter (6 with Medtronic React 71 and 1 with Route 92 Medical Hipoint 70), while 13 were treated with Tenzing 8 paired with a super‐large bore catheter (11 with Route 92 Medical Hipoint 88 catheter and 2 with Route 92 Medical Freeclimb 88 catheter). …”
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CNN–Transformer Hybrid Architecture for Underwater Sonar Image Segmentation by Juan Lei, Huigang Wang, Zelin Lei, Jiayuan Li, Shaowei Rong

“…FLSSNet is built upon a CNN and Transformer backbone network, integrating four core submodules to address various technical challenges: (1) The asymmetric dual encoder–decoder (ADED) is capable of simultaneously extracting features from different modalities and systematically modeling both local contextual information and global spatial structure. (2) The Transformer feature converter (TFC) module optimizes the multimodal feature fusion process through feature transformation and channel compression. (3) The long-range correlation attention (LRCA) module enhances CNN’s ability to model long-range dependencies through the collaborative use of convolutional kernels, selective sequential scanning, and attention mechanisms, while effectively suppressing noise interference. (4) The recursive contour refinement (RCR) model refines edge contour information through a layer-by-layer recursive mechanism, achieving greater precision in boundary details. …”
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Changes in Respiratory Function Before and After Cardiopulmonary Bypass in Children with Congenital Heart Disease with Increased or Decreased Pulmonary Blood Flow by Liang L, Hou A, Xi H, Yang J, Liu C

“…The external diameter of the pulmonary artery among patients in Group A was significantly larger than that in Group B (2.50± 0.38 vs 1.31± 0.29 cm, p &lt; 0.05), while the external diameter of the aorta was significantly smaller in those in Group A compared to Group B (1.60± 0.26 vs 1.91± 0.37, p &lt; 0.05). …”
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Bridging Knowledge Gaps: The Influence of Structured Education on Parental Knowledge and Attitude towards the Right to Education in Community by Neha Anil Katakwar, Darshana Wankhede, Bibin Kurian, Archana Maurya

“…Education plays a major role in creating an optimal environment and encouraging openness and effective governance within an entity. …”
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The application of PET/CT with 18F-FDG in the differential diagnosis of lung solitary lesions by G. V. Afonin, A. E. Glukhareva, E. I. Smolenov, I. V. Kolobaev, E. E. Beketov, L. O. Petrov, S. A. Ivanov

“…The study was aimed to investigate the effectiveness of PET / CT with 18 fluoro‑2 deoxy-D-glucose (18F-FDG) in the differential diagnosis of focal lung neoplasms.Materials and methods. Patients (n = 108) with newly diagnosed lung focal lesions were enrolled in the study. …”
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SPP1+ tumor-associated macrophages define a high-risk subgroup and inform personalized therapy in hepatocellular carcinoma by Wei-Xuan Xu, Ya-Mei Ye, Jia-Lin Chen, Xin-Ying Guo, Chen Li, Juan Luo, Lin-Bin Lu, Xiong Chen

“…However, their clinical and therapeutic implications remain unexplored.MethodsUtilizing a large-scale sc-RNA seq dataset, a landscape of HCC cellular ecosystem was depicted. …”
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Adapting the Germ Defence Web-Based Intervention to Improve Infection Prevention and Control in Care Homes: Interview Study Among Care Home Staff by Alex Hall, Johanna Aguilera-Muñoz, Lisa McGarrigle, Charlotte Eost-Telling, James Denison-Day, Christie Cabral, Merlin Willcox, Chris Todd

“…ObjectiveThis study aimed to evaluate how an evidence-based, digital behavior change intervention called Germ Defence can be rapidly adapted to meet the needs of care homes. MethodsThis study applied the person-based approach, which emphasizes iterative approaches to optimizing interventions via individual user feedback. …”
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