Sildenafil’s effectiveness in the primary coronary slow flow phenomenon: a pilot randomised controlled clinical trial by Abbas Andishmand, Seyedmostafa Seyedhosseini, Seyedeh Mahdieh Namayandeh, Elnaz Adelzadeh, Amin Entezari, Seyed Reza Mirjalili

“…Nevertheless, there is not any agreement on the optimal treatment for primary CSFP, so we decided to examine the effectiveness of sildenafil in this context.Methods This pilot study is a 12-week, triple-blind, randomised, placebo-controlled trial for receiving either 50 mg daily oral sildenafil or placebo. …”
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Exploring the Utility of the Modified Hospitalized‐Patient One‐Year Mortality Risk Score to Trigger Referrals to Palliative Care for Inpatients With Cancer by A. Ghoshal, R. Prince, J. Downar, J. Lapenskie, S. Subramaniam, P. Wegier, L. W. Le, B. Hannon

“…However, the developer‐recommended mHOMR cut‐off of 0.21 failed to identify a statistically significant difference between patients with advanced cancer at low versus high scores. While mHOMR may be a useful tool to augment clinical judgment and identify inpatients with advanced cancer at high risk of death, who in turn may benefit from referral to palliative care, the optimal mHOMR cutoff may warrant adjustment for this population.…”
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A PROSPECTIVE OBSERVATIONAL STUDY ON TOTAL KNEE REPLACEMENT OUTCOMES IN OSTEOARTHRITIC KNEES WITH VARUS DEFORMITY. by Dr. Ch Ramesh Babu, Dr. Banna Kiran Kumar, Dr. Kiran Kumar Joshi, Dr. Pradeep Kumar, Dr. Manoj Kumar

“…Clinical and functional status were assessed using the Knee Society Score (KSS), while radiological evaluation confirmed prosthetic alignment. …”
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Practical Aspects of the Implementation of Screening for the Detection of Malignant Neoplasms of the Cervix during the Medical Examination by O. B. Kuleshova, E. A. Domonova, T. N. Romanuk, A. N. Gerasimov, E. M. Voronin, V. G. Akimkin

“…The study of the population structure of circulating human papillоmavirus (HPV) types, and evaluation of the effectiveness of the recommended diagnostic models will improve the direction of the fight against cervical cancer and introduce optimal preventive solutions.Aim. Retrospective analysis of screening effectiveness for the detection of malignant neoplasms of the cervix, carried out during the medical examination in one institution of Moscow.Materials and methods. …”
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MWB_Analyzer: An Automated Embedded System for Real-Time Quantitative Analysis of Morphine Withdrawal Behaviors in Rodents by Moran Zhang, Qianqian Li, Shunhang Li, Binxian Sun, Zhuli Wu, Jinxuan Liu, Xingchao Geng, Fangyi Chen

“…The goal is to enhance toxicological assessments of CNS-active substances through robust, scalable behavioral phenotyping. <b>Methods:</b> MWB_Analyzer integrates optimized multi-angle video capture, real-time signal processing, and machine learning-driven behavioral classification. …”
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Liver metastases in thyroid cancer: epidemiology, risk stratification and survival outcomes in the immunotherapy era by Ming-Lu Xu, Yang-Yang Wang, Li-Ping Xie, Ning Ding, Jia-Jun Hui

“…Logistic regression analyses were employed to identify the predictors for liver metastases, while survival determinants were determined using Cox regression models. …”
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Bibliometric Analysis of microRNA: A Comprehensive Evaluation of Its Contribution to Acute Coronary Syndromes by Gao Y, Li T, Mu X, Ren X, Wang J, Fan J, Zhu H, Wang X

“…Harbin Medical University was the most productive institution, while Thum Thomas emerged as the leading researcher. …”
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Engaging Victims: The Aceh KKR’s Communication Strategy in Data Acquisition by Zakirah Azman, Zurrafiqah Zurrafiqah, Nur Anisah, Nadia Muharman

“…KKR also relies heavily on conventional media, which limits its outreach. Optimizing digital media and refining engagement methods would strengthen its communication effectiveness in addressing victims' needs.   …”
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Evaluation of anthropometric parameters based on emotional eating by Martina Gažarová, Natalia Tobola

“…Background Emotions and moods are important regulators of food intake. While initially excessive intake, especially of unhealthy foods, was associated with negative emotions, now the emphasis is also on positive ones. …”
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The added value of quantitative contrast-enhanced CT parameters in distinguishing malignant from benign solid pulmonary nodules by Peng Yun, Zhencheng Zhan, Zijing Wu, Yutong Rao, Ke Sun, Lianggeng Gong

“…Abstract Purpose To explore the added value of quantitative parameters derived from routine chest contrast-enhanced computed tomography (CECT) in distinguishing malignant from benign solid pulmonary nodules (SPNs). Methods Eighty-one SPNs pathologically confirmed as benign or malignant with preoperative nonenhanced chest and CECT scans were retrospectively analyzed. …”
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Understanding External Peak Demands in Elite vs. Non-Elite Male Basketball Players by Yoel Antoranz, Enrique Alonso-Pérez-Chao, Carlos Mª Tejero-González, Hugo Salazar, Juan del Campo-Vecino, Sergio L. Jiménez-Sáiz

“…Background: Understanding the physical demands of basketball at different competitive levels is essential for optimizing training and performance. While elite players are often assumed to experience the highest physical loads, evidence comparing peak external demands (PDs) between elite and non-elite athletes using time-window analysis is limited. …”
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Innovative use of indigenous dadih probiotics to enhance feed intake, digestibility, growth performance, and health in heat-stressed Sapera goats by Nurzainah Ginting, Edhy Mirwandhono, Nurjama’yah Br. Ketaren, Yuan-Yu Lin

“…Supplementation with 4 cc dadih optimized performance without disrupting hematological homeostasis, while 8 cc effectively suppressed gut pathogens. …”
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Is restriction of intravenous fluid beneficial for septic shock in ICU patients? A meta-analysis of randomized controlled trials by Yushan Duan, Yue Yin, Jinxi Yue, Weihua Zhu, Xiumei Yang, Yiming Ma, Xiaohong Wan, Yuan Yang

“…The primary outcomes of our analysis included acute kidney injury incidence and ICU mortality, while the secondary outcomes encompassed mechanical ventilation requirement and ischemic event incidence. …”
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Errors in Differential Diagnosis of Burn Injury at the Prehospital Stage by O. S. Pankrateva, Yu. V. Yurova, P. K. Krylov, E. V. Zinoviev, D. O. Vagner, L. M. Likhonos

“…To study the structure of diagnostic errors at the prehospital stage of the EMS to optimize patient routing by improving the existing organizational and methodological standards.Material and methods. …”
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Can open source large language models be used for tumor documentation in Germany?—An evaluation on urological doctors’ notes by Stefan Lenz, Arsenij Ustjanzew, Marco Jeray, Meike Ressing, Torsten Panholzer

“…Models with less extensive training data or having fewer than 7 billion parameters showed notably lower performance, while larger models did not display performance gains. …”
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Experimental study of the temperature distribution in long tubular bones with a periossal arrangement of heaters by D. O. Pakhmurin, V. V. Pakhmurina, I. I. Anisenya, P. K. Sitnikov

“…To ensure reaching the required temperature (60°C) within a short time (15–20 min) while maintaining optimal temperature parameters, it was proposed to develop variable temperature modes that would combine the initial use of the maximum heating mode until reaching the desired temperature in medullary cavity, followed by switching to a constant temperature mode, which allowed maintaining the achieved temperature level during therapeutic exposure.…”
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Distribution and Antimicrobial Resistance Analysis of Blood Culture Isolates at a Chinese National Cardiovascular Regional Medical Center: A 7-Year Retrospective Study by Wang Q, Wu F, Li T

“…Qian Wang, Fan Wu, Tao Li Department of Medical Laboratory, Fuwai Central China Cardiovascular Hospital/Central China Fuwai Hospital of Zhengzhou University/Henan Provincial People’s Hospital, Zhengzhou, Henan, 451464, People’s Republic of ChinaCorrespondence: Tao Li, Department of Medical Laboratory, Fuwai Central China Cardiovascular Hospital/Central China Fuwai Hospital of Zhengzhou University/Henan Provincial People’s Hospital, Zhengzhou, Henan, 451464, People’s Republic of China, Email zzlitao@zzu.edu.cnPurpose: This study aimed to characterize the epidemiological patterns and antimicrobial resistance profiles of bloodstream infections (BSIs) in a cardiovascular specialty hospital and to identify region-specific pathogen distributions, resistance risks, and clinical implications for optimizing empirical therapy and infection control strategies.Patients and Methods: A retrospective analysis (2018– 2024) evaluated 1,055 non-duplicate BSI isolates from 37,576 blood cultures at the Fuwai Central China Cardiovascular Hospital. …”
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Diagnostic Performance of Serum Mac-2-Binding Protein Glycosylation Isomer as a Fibrosis Biomarker in Non-Obese and Obese Patients with MASLD by Prooksa Ananchuensook, Kamonchanok Moonlisarn, Bootsakorn Boonkaew, Chalermarat Bunchorntavakul, Pisit Tangkijvanich

“…The performance of M2BPGi was consistent among subgroups according to BMI, while the AUROCs of FIB-4, APRI, and NFS were remarkably decreased in patients with BMI ≥ 30 kg/m². …”
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Impact of arm position on low dose dual-source CT one-step aortic and cerebral-carotid artery angiography image quality and radiation dose by Meng Wang, Chao Zheng, Lin Yang, Juan Su, Jiexin Sheng, Xiaolong He, Bo Wang, GuangHang Wu

“…The impact of varying arm positions on radiation dose and image quality is unknown when optimizing the scan protocol. This study aims to determine the best scanning protocol to minimize radiation dose while maintaining image quality, as well as how arm position impacts radiation dose and image quality of low dose one-stop cerebral carotid aortic CTA. …”
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MHC class II-mediated spontaneous rejection of breast carcinomas expressing model neoantigens by James William Jenkins, Alvaro Peña, Sarah A Castro, Michael J Hansen, Virginia P Van Keulen, Sean T Foster, Pablo E Rios-Cruz, Joshua Yakubov, Destin T Hinson, Samuel M Olivier, Kevin D Pavelko, Sara J Felts, Aaron J Johnson, Larry R Pease

“…Background Cancers persist despite expression of immunogenic neoantigens and ongoing antitumor immune responses. While some occult tumors likely are cleared by effective antitumor immune responses, the targeted antigens are not easily identifiable as those tumors spontaneously disappear.Methods We used mouse models with a defined antigenic protein mimicking tumor-specific neoantigens to address the nature of these spontaneous anti-tumor immune responses.Results BALB/c (H-2d) mice challenged with BALB/c breast tumors expressing the rat-erbB2 oncoprotein succumb to their tumors despite ongoing immune responses targeting tumor-specific model antigens. …”
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