Validation of the EVendo score for assessing high-risk varices in Western European patients with cirrhosis by Julian Müller-Kühnle, Christian Benignus, Severin Schricker, Moritz Schanz, Julia Todoroff, Jörg Latus, Wolfram Zoller, Dominik Marschner

“…Background : Gastroesophageal varices (GEV) and associated bleeding are serious complications of cirrhosis, leading to considerable morbidity and mortality. While esophagogastroduodenoscopy (EGD) remains the gold standard for detecting GEV, it is an invasive procedure. …”
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Development and validation of an interpretable multi-task model to predict outcomes in patients with rhabdomyolysis: a multicenter retrospective cohort studyResearch in context by Chunli Liu, Jie Shi, Fengjuan Wang, Duo Li, Yu Luo, Bofan Yang, Yunlong Zhao, Li Zhang, Dingwei Yang, Heng Jin, Jie Song, Xiaoqin Guo, Haojun Fan, Qi Lv

“…Data from eICU-CRD and MIMIC-IV were combined to form the derivation cohort for model training and internal validation, while data from the Chinese hospitals served as the external validation cohort. …”
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Сombat wounds microflora in modern warfare by V. P. Kovalchuk, N. S. Fomina, V. M. Kondratiuk, О. О. Fomin, Y. V. Lazarenko, K. V. Gumenyuk

“…Analysis of the clonal characteristics and antibiotic resistance of the most prevalent wound pathogens among individuals injured in the Russian-Ukrainian war to support microbiota surveillance of combat wounds and optimize treatment strategies. Materials and Methods. …”
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Calculation Model of Multi-roll Straightening Process Based on Bilinear Hardening and Power Hardening by ZHU Xiaoyu, CHENG Zixing, WANG Xiaogang, HAN Peisheng

“…The goal is to support the development of straightening techniques for new materials and provide a theoretical basis for intelligent straightening and optimal design of straightening machines.MethodsThree material models—ideal elastic-plastic, bilinear hardening, and power hardening—were selected, and the curvature-moment (M‒K) relationships for these materials during bending were derived. …”
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MicroRNAs in anthracycline cardiotoxicity: biomarkers, mechanisms, and therapeutic advances by Hongyun Mao, Hongyun Mao, Jing Hu, Chenshuo Yu, Sicong Xie, Cheng Chang, Juanjuan Peng, Yang Zhang

“…MicroRNAs (miRNAs), as key post-transcriptional regulators of gene expression, play a pivotal role in the pathophysiology of cardiovascular disease, but their specific functions in anthracycline-induced cardiotoxicity (AIC) require systematic elucidation.PurposeThis review aims to systematically summarize current research on the key miRNAs, their molecular targets, and associated signaling pathways that regulate AIC, while also exploring their potential as biomarkers for early diagnosis and as therapeutic targets for intervention.MethodsA comprehensive literature search was conducted in PubMed, Web of Science, and Scopus databases for relevant studies published up to April 2025. …”
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Comparative Pharmacological Assessment of Amoxicillin in Five Cultured Fish Species: Implications for Off-Label Use in Aquaculture by Jun Sung Bae, Chae Won Lee, Chan Yeong Yang, Eun Ha Jeong, Bosung Kim, Kwan Ha Park, Jung Soo Seo, Mun-Gyeong Kwon, Ji-Hoon Lee

“…<b>Results</b>: AMOX, at 40 mg/kg, significantly reduced bacterial loads in olive flounder, rainbow trout, and Japanese eel (<i>p</i> < 0.05), while Israeli carp exhibited a limited response (<i>p</i> = 0.54). …”
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Discovery of Small Molecules Against Foot-and-Mouth Disease Virus Replication by Targeting 2C Helicase Activity by Saisai Zhou, Suyu Mu, Shuqi Yu, Yang Tian, Sijia Lu, Zhen Li, Hao Wu, Jiaying Zhao, Huanchun Chen, Shiqi Sun, Yunfeng Song

“…Background: The 2C protein of foot-and-mouth disease virus (FMDV), a member of helicase superfamily 3 (SF3), drives viral genome replication and serves as a critical target for antiviral drug development. Methods: A fluorescence resonance energy transfer (FRET)-based high-throughput screening (HTS) platform was developed to identify 2C helicase inhibitors. …”
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Risk Factors of Ankle Sprain in Soccer Players: A Systematic Review and Meta-Analysis by Amir Human Hoveidaei, Amir Reza Moradi, Amin Nakhostin-Ansari, Mohammad Mehdi Mousavi Nasab, Seyed Pouya Taghavi, Shayan Eghdami, Bijan Forogh, Masumeh Bagherzadeh Cham, Christopher J. Murdock

“…BMI emerged as a risk factor in three out of seven studies, while age and height were significant in one out of six studies each. …”
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The association between acute kidney injury and dysglycaemia in critically ill patients with and without diabetes mellitus: a retrospective single-center study by Chong Zhang, Meng Ning, Weiru Liang, Wei Su, Yi Chen, Tingting Guo, Kun Hu, Wenjin Peng, Yingwu Liu

“…Further research is needed to develop optimal glycemic control strategies for AKI patients.…”
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Characteristics of adenomyosis in secondary infertility patients on MRI and factors associated with fertility recovery after HIFU by Zhiyun Yang, Jinfeng Lin, Tao Tan, Yuan Li, Ying Chen, Meijie Yang, Zhibo Xiao, Jinyun Chen

“…Objective To study the MRI characteristics of adenomyosis in secondary infertility patients, and to analyze the factors affecting pregnancy after High-intensity focused ultrasound (HIFU).Methods Clinical data of 388 patients with adenomyosis were selected from January 2014 to December 2019 treated with HIFU They were divided into the infertility group and the control group by the presence of secondary infertility. …”
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Determinants of patient satisfaction among outpatients with chronic illnesses in the region of medina, Saudi Arabia: a cross-sectional study by Mustafa S. Alhasan, Ibrahim M. Alahmadi, Hassan F. Alhilali, Nawaf M. Alyoubi, Nasser A. Alkhoriji, Ahmad M. Aljazairi, Basil M. Othman, Abdulrahim M. Alshehri, Mohammad O. Alhejaili, Baraa Alhejaili, Omar I. Alanazi, Ahmed Y. Azzam, Ayman S. Alhasan

“…Accessibility and convenience scored lowest (60% satisfaction), while interpersonal manner, communication, and financial aspects achieved highest scores (70% satisfaction). …”
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Efficacy of Low‐Dose Fluconazole for Primary Prophylaxis of Invasive Candida Infections in Patients With Acute Leukemia: A Double‐Blind Randomized Clinical Trial by Roghayeh Savary‐Kouzehkonan, Kourosh Sadeghi, Soroush Rad, Neda Alijani, Zohreh Baseri, Mohammad Vaezi, Seyed Asadollah Mousavi, Bita Shahrami

“…ABSTRACT Background Invasive fungal infections (IFIs), particularly Candida infections, are a significant cause of morbidity and mortality in patients with acute leukemia. While fluconazole is widely used for prophylaxis, the optimal dosing regimen remains uncertain. …”
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Influence of Amino Acids on Quorum Sensing-Related Pathways in <i>Pseudomonas aeruginosa</i> PAO1: Insights from the GEM iJD1249 by Javier Alejandro Delgado-Nungaray, Luis Joel Figueroa-Yáñez, Eire Reynaga-Delgado, Mario Alberto García-Ramírez, Karla Esperanza Aguilar-Corona, Orfil Gonzalez-Reynoso

“…Results: Among the tested AAs, D-Met was the only one that did not enhance the growth rate of <i>P. aeruginosa</i> PAO1, while L-Arg and L-Orn increased fluxes in the L-methionine biosynthesis pathway, influencing the <i>metH</i> gene. …”
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Trends and future burden of other musculoskeletal diseases in China (1990–2041): a comparative analysis with G20 countries using GBD data by Meifeng Lu, GuiHao Zheng, Xin Shen, Yulong Ouyang, Bei Hu, Shuilin Chen, Guicai Sun

“…Period effects showed a rising trend, while cohort effects revealed declining prevalence and YLDs rates. …”
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Comparative Analysis of SARS-CoV-2 Antibodies in Diabetic and Non-Diabetic Healthcare Workers Post-Infection and Vaccination by Mariya Rouf Tramboo1*, Anjum Farhana1, Danish Zahoor1, Ilhaam Iqbal1, Zahoor Mohuiddin1

“…Diabetic individuals had lower antibody titers, while age and gender differences also affected antibody responses. …”
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Explainable AI for Lightweight Network Traffic Classification Using Depthwise Separable Convolutions by Mustafa Ghaleb, Mosab Hamdan, Abdulaziz Y. Barnawi, Muhammad Gambo, Abubakar Danasabe, Saheed Bello, Aliyu Habib

“…With the rapid growth of internet usage and the increasing number of connected devices, there is a critical need for advanced Network Traffic Classification (NTC) solutions to ensure optimal performance and robust security. Traditional NTC methods, such as port-based analysis and deep packet inspection, struggle to cope with modern network complexities, particularly dynamic port allocation and encrypted traffic. …”
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Comparing Four Video Laryngoscopes and One Optical Laryngoscope with a Standard Macintosh Blade in a Simulated Trapped Car Accident Victim by Florian J. Raimann, Daniel M. Tepperis, Dirk Meininger, Kai Zacharowski, Richard Schalk, Christian Byhahn, Christian F. Weber, Haitham Mutlak

“…Methods. A mannequin with a cervical collar was placed on the driver’s seat. …”
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Bleomycin Electrosclerotherapy (BEST) for Slow-Flow Malformations of the Upper Aerodigestive Tract by Veronika Vielsmeier, Vanessa F. Schmidt, Florian Obereisenbuchner, Natascha Platz Batista da Silva, Walter A. Wohlgemuth, Daniel Puhr-Westerheide, Max Seidensticker, Jens Ricke, Thomas Kühnel, Christopher Bohr, Moritz Wildgruber, Caroline T. Seebauer

“…<b>Background/Objectives:</b> Bleomycin electrosclerotherapy (BEST), which combines intralesional bleomycin administration with electroporation, enhances drug uptake and has shown efficacy in treating vascular malformations resistant to conventional therapies. While BEST is increasingly used in various anatomical sites, its application in the upper aerodigestive tract remains underexplored. …”
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Development of reference intervals for serum biochemistry in female Hanwoo cattle with different reproductive status by Sung-Ho Kim, Tae-Gyun Kim, Sang-Yup Lee, Saet-Byul Kim, Young-Bum Son, Seung-Joon Kim, Won-Jae Lee

“…Methods: Blood samples were collected from female Hanwoo cattle, categorized as pregnant (n = 12), non-pregnant (n = 25), and fattening (n = 11). …”
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Predictors and Clinical Impacts of Impaired Heart Rate Variability in Women with Breast Cancer by İmran Ceren, Beyza Nur Çitir Durmuşoğlu, Yusuf Ziya Şener, Fadime Bozduman Habip, Sedat Köroğlu, Necla Demir, Öztürk Ateş, Elif Eroğlu Büyüköner

“…<i>Background and Objectives</i>: Breast cancer (BC) is the most prevalent cancer globally, with a significant mortality rate, especially among women. While advances in treatment have reduced BC mortality, cardiovascular complications resulting from anticancer therapies have become a major concern. …”
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