Left atrial stiffness index in the identification of heart failure with preserved ejection fraction by N. E. Shirokov, E. I. Yaroslavskaya, M. D. Kosterin, D. V. Krinochkin, E. A. Gorbatenko, T. N. Enina, N. A. Musikhina

“…To study the diagnostic value of the left atrial stiffness index (LASI) of heart failure with preserved ejection fraction (HFpEF) depending assessed by transthoracic echocardiography (TTE) in the diagnosis on diastolic stress test (DST) results.Material and methods. DST was performed in cases of insufficient criteria for increased left ventricular filling pressure assessed by TTE. …”
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Effects of opioid-free anesthesia combined with iliofascial nerve block on perioperative neurocognitive deficits in elderly patients undergoing hip fracture surgery: study protocol... by Tong Zhi, Shirong Wei, Jiao Kuang, Sitong Zhou, Danhong Yu, Tesheng Gao, Long Lei, Chengfei Xu, Liang Cheng, Qinghe Zhou, Ming Yao, Huadong Ni

“…Where emerging evidence suggests opioid-free anesthesia (OFA) strategies could maintain analgesic efficacy while potentially attenuating opioid-associated neuroinflammatory mechanisms implicated in PND pathogenesis. …”
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Using proximal sensor data for soil salinity management and mapping by Yan GUO, Yin ZHOU, Lian-qing ZHOU, Ting LIU, Lai-gang WANG, Yong-zheng CHENG, Jia HE, Guo-qing ZHENG

“…We concluded that two management zones are optimal to guide precision management. Zone A had an average salinity level of about 165 mS m−1, in which salt-tolerant crops, such as cotton and barley can grow normally, while crops such as soybean and cowpeas may be planted using leaching and increasing the mulching film methods to reduce the accumulation of salt in surface soil. …”
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Natural killer cell as a potential predictive biomarker for early immune checkpoint inhibitor-associated cardiovascular adverse events: a retrospective cohort study by Yujuan Wu, Diansa Gao, Li Tan, Zhulu Chen, Chuan Zhang, Min Mao, Yuxi Zhu, Yuxi Zhu, Yuxi Zhu, Yue Liu, Zhong Zuo

“…Receiver operating characteristic (ROC) curve analysis determined optimal cutoff values for potential biomarkers. Propensity score matching (PSM) was used to validate the predictive value of baseline NK cell proportion for CAVEs.ResultsScRNA-seq data revealed decreased CD8+ T and B cell proportions in the CVAEs group, while NK cell proportions increased. …”
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Standardization of indoor radon measurements based on rational criterion for conformity assessment by A. A. Tsapalov, S. M. Kiselev, K. L. Kovler, P. S. Miklyaev, T. B. Petrova, M. V. Zhukovsky, I. V. Yarmoshenko, A. M. Marennyy, O. E. Tutelyan, S. I. Kuvshinnikov

“…It also proposes a rationale for optimizing indoor radon monitoring through the participation of not only professional inspectors, but also the population itself due to the possibility of introducing simple methods and inexpensive radon devices within the rational criterion.…”
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A deep dive into the surgical and pharmacological considerations of obesity in chronic myeloid leukemia: a narrative review by Rola Ghasoub, Basant Elsayed, Maria Benkhadra, Giuseppe Saglio, Jorge Cortes, Mohamed Elmarasi, Engy Elsayed, Ahmed Adel Elsabagh, Ibrahim Elmakaty, Abdelrahman Elsayed, Mohamed Yassin, Mohamed Yassin

“…This review aims to summarize the existing literature regarding CML management in patients with obesity and related surgeries, providing novel recommendations for their medical and surgical management.MethodsA narrative review was performed, analyzing English-language articles published up to 2024. …”
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Artificial intelligence in nephrology education: a multicenter survey of fellowship trainees at Mayo Clinic by Mohammad S. Sheikh, Charat Thongprayoon, Iasmina M. Craici, Jing Miao, Fawad M. Qureshi, Michael A. Mao, Musab S. Hommos, Mary Prendergast, Sumi Nair, Kianoush B. Kashani, Wisit Cheungpasitporn

“…Interactive workshops emerged as the preferred modality for AI training (52%), with limited knowledge cited as the primary barrier to adoption. Optimism was especially high regarding AI applications in predictive modeling (86%) and diagnostic imaging (81%), while confidence in AI for direct clinical decision-making remained cautious.ConclusionThere is significant interest among nephrology fellows in AI, along with a critical need for formal education and training. …”
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Does transcutaneous auricular vagus nerve stimulation alter pupil dilation? A living Bayesian meta-analysis by Ipek Pervaz, Lilly Thurn, Cecilia Vezzani, Luisa Kaluza, Anne Kühnel, Nils B. Kroemer

“…Nevertheless, studies on the effectiveness of various tVNS protocols have produced heterogeneous results on pupil dilation to date. Methods: Here, we synthesize the existing evidence and compare conventional (“continuous”) and pulsed stimulation protocols using a Bayesian meta-analysis. …”
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Theaflavins enhances laying hen production performance and egg antioxidant capacity via improving antioxidant status and regulating lipid metabolism by Ling Zhou, Pinyao Zhao, Jinwei Zhang, Jie Zhong, Yulin Rao, Jia Tang, Longsheng Jiang, Fen Chen, Lijuan Chen, Keying Zhang, Weimin Ouyang, Jialong Peng

“…Based on the quadratic regression analysis, the optimal TF supplementation level was determined to be 500 mg/kg.…”
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Machine learning algorithms to predict epidural-related maternal fever: a retrospective study by Xiaohui Guo, Xiaohui Guo, Xiaohui Guo, Haixia Zhang, Haixia Zhang, Haixia Zhang, Hongliang Mei, Hongliang Mei, Hongliang Mei

“…The AUC ratios between the logistic regression (LR) model and the stochastic gradient descent (SGD) models showed statistical significance (p < 0.05), while the differences between the other models were not statistically significant. …”
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Interfacial oxygen nanobubble for mitigating the methane emissions from aquatic ecosystems: A review by Qingnan Chu, Xiangyu Liu, Detian Li, Shuai Yin, Ping He, Wenjuan Li, Chengrong Chen, Zhimin Sha

“…Despite their potential, challenges remain in optimizing oxygen-loading capacity, assessing long-term ecological impacts, and scaling up production. …”
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Insight into the management of patients with melanoma in times of the COVID-19 pandemic: A single-center experience by Nikolić Jelena, Marinković Marija, Jovanović Mladen, Mijatov Ivana, Leković-Stojanov Dragana, Kecman Stefan

“…Thin melanoma percentage as a measurement of successful screening programs decreased significantly during the COVID-19 pandemic (11.57% vs. 24.01%), while median Breslow thickness remained stable. The distribution of different histological types was consistent across both periods. …”
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Effect of Head Rotation on Cerebral Blood Velocity in the Prone Position by Jakob Højlund, Marie Sandmand, Morten Sonne, Teit Mantoni, Henrik L. Jørgensen, Bo Belhage, Johannes J. van Lieshout, Frank C. Pott

“…Prone positioning with rotated head affects both CBF and cerebrovenous drainage indicating that optimal brain perfusion requires head centering.…”
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Simulation-free cone beam CT-based online adaptive radiotherapy for metastatic spinal cord compression by Lisette Sandt, Evangelos Giannoulis, Laura Ann Rechner, Lina Åström, Anna Mann Nielsen, Jens Morgenthaler Edmund, Gitte Fredberg Persson

“…Patient/material and methods: Diagnostic CT scans from patients diagnosed with MSCC were used for treatment planning, while CBCT scans from their first treatment session were retrospectively used to emulate the treatments. …”
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Management of immune-related adverse events under PD-1/PD-L1 inhibitors: Insights from a Moroccan real-world experience by Inès Cherradi, Mohamed Ichou, Mohammed Squalli Houssaini, Nabil Ismaili

“…Most toxicities were grade 1-2, while 2 patients developed severe grade 3 pneumonitis and colitis, requiring hospitalization. …”
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Enhancing Specificity in Predicting Axillary Lymph Node Metastasis in Breast Cancer through an Interpretable Machine Learning Model with CEM and Ultrasound Integration by Weimin Xu PhD, Bowen Zheng MS, Chanjuan Wen PhD, Hui Zeng MS, Sina Wang MS, Zilong He PhD, Xin Liao MS, Weiguo Chen MS, Yingjia Li PhD, Genggeng Qin PhD

“…Among these, the LightGBM achieved the highest AUC (0.762) and specificity (86.67%, while the ensemble model using RF as the meta-model had an AUC (0.754) and specificity (83.33%. …”
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Machine learning-based integration develops relapse related signature for predicting prognosis and indicating immune microenvironment infiltration in breast cancer by Junyi Li, Shixin Li, Dongpo Zhang, Yibing Zhu, Yue Wang, Xiaoxiao Xing, Juefei Mo, Yong Zhang, Daixiang Liao, Jun Li

“…Abstract Breast cancer is the most common type of cancer in women, and while current treatments can cure the majority of early-stage primary BC cases, recurrence remains a significant challenge. …”
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Platelet response following dexamethasone in obese vs nonobese patients with primary, acute immune-mediated thrombocytopenia by Tyler Everhardt, Kelley Julian, Russell Benefield, Aaron Wilson, Nathan Wilson, Charles J. Parker, Anna Parks, Jeffrey A. Gilreath

“…Objectives: We aimed to evaluate if body weight altered the response rates to dexamethasone (DEX) in the treatment of ITP. Methods: We conducted a retrospective review to evaluate the effects of body weight on response to DEX in ITP. …”
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A newly modified nerve-sparing radical hysterectomy technique with analysis of short-term oncologic, surgical, and functional outcomes by Shichao Han, Shichao Han, Xinyou Wang, Xinyou Wang, Jinming Zhu, Ya Li, Ya Li, Jing Na, Jing Na, Jun Wang, Jun Wang

“…In clinical practice, utilizing the three-plane structure of the paracolpium and medially lifting the vascular plane facilitated safe, reliable dissection, exposure, and preservation of pelvic autonomic nerve function.Through clinical practice, follow-up, and analysis of 55 cases, it was observed that combining the concept of membrane anatomy with the three-plane anatomical structure of the paracolpium not only enables nerve-sparing radical hysterectomy as a bloodless surgical procedure but also ensures optimal nerve preservation, favorable oncological outcomes, and a significant reduction in perioperative complications.ConclusionGuided by the principles of membrane anatomy and the three-plane theory of the paracolpium, nerve-sparing radical hysterectomy facilitates precise preservation of pelvic autonomic nerve function in a bloodless manner, while achieving favorable oncological outcomes.…”
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Updating the Brazilian clinical practice guidelines for sickle cell disease: Recommendations and development process by Ludmila Peres Gargano, Mariana Millan Fachi, Layssa Andrade Oliveira, Clarisse Lobo, Katharina Nelly Tobos Melnikoff, Selma Soriano, Marta da Cunha Lobo Souto Maior, Meline Rossetto Kron-Rodrigues, Dalila Fernandes Gomes, Haliton Alves Oliveira Junior, Rosa Camila Lucchetta

“…Dissemination and integration aim to enhance healthcare delivery, while future assessments should optimize real-world implementation.…”
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