Regularity and mechanisms of water-sand inrushes within mining-activated faults by Shichuan ZHANG, Pu HUANG, Yangyang LI, Chenggong WANG, Zhenhua WU

“…Small or large sand grain sizes were prone to cause system instability, while moderate grain sizes could balance permeability and system stability. …”
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Performance measures of the medical priority dispatch system in an urban basic life support system by Vittorio Nicoletta, Maxime Robitaille-Fortin, Valérie Bélanger, Éric Mercier, Jessica Harrisson

“…Abstract Background Accurate dispatch prioritization for emergency medical services (EMS) is essential for optimizing resource allocation and ensuring timely emergency response. …”
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Cost-effectiveness analysis of penpulimab plus carboplatin-paclitaxel as first-line treatment for metastatic squamous non-small-cell lung cancer in China by Luwei Wang, Jiasheng Chen, Lihui Lin, Xiaowei Huang

“…Clinical efficacy data were sourced from the AK105-302 trial, while drug costs were derived from national tender prices. …”
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Predicting Oncological and Functional Outcomes by Nephrectomy Type for T1 Renal Tumors Using Machine Learning Models by Dongrul Shin, Maisy Song, Jungyo Suh, Cheryn Song

“…Purpose Determining the optimal surgical approach for patients with T1 renal tumors requires balancing long-term oncological and renal functional outcomes. …”
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Auditory evoked potential wave VI as an objective indicator of sedation depth in neonates undergoing chloral hydrate sedation: a double-blind randomized controlled study by Zong Zheng, Shanpu Yang, Hongyan Liu, Zhimin Sheng

“…We aimed to determine whether wave VI could function as an objective indicator of sedation levels in neonates.MethodsThis prospective, double-blind, randomized trial enrolled 100 neonates requiring hearing screening. …”
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The PRIME model: a management solution in academic medicine by Gert J. van Zyl, Maria Nel

“…Methods: A descriptive, explanatory survey comprising a literature review, a questionnaire survey and a Delphi process was performed. …”
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Single-cell sequencing reveals tumor microenvironment features associated with the response to neoadjuvant immunochemotherapy in oral squamous cell carcinoma by Pu-Gen An, Wen-Jie Wu, Xiao Hu, Zi-Qi Zhang, Jie Zhang

“…This study aimed to analyze the impact of neoadjuvant chemoimmunotherapy (NACI) on the tumor microenvironment of OSCC via single-cell RNA sequencing, with the goal of optimizing treatment strategies. Methods We analyzed biopsy, primary tumor, matched metastatic lymph node, and normal lymph node samples from four patients with OSCC receiving two cycles of tislelizumab (200 mg), albumin-bound paclitaxel (260 mg/m2), and cisplatin (60–75 mg/m2), with 3-week intervals between each cycle. …”
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Economic Superiority of PIP Slip Joint Compared to Conventional Tubular Joints by Md Ariful Islam, Sajid Ali, Hongbae Park, Daeyong Lee

“…As PIP slip joints yield a higher net present value (NPV), a shorter payback period, and a lower LCOE, they can enhance profitability and reduce financial risk, and are suitable for streamlined implementation. While grouted and bolted flange joints exhibit similar financial performance, PIP slip joints’ minimal expenditure and consistent superiority make them the optimal choice for sustainable and economically viable offshore wind projects.…”
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Predictors of mothers’ home cord care, breastfeeding, and thermoregulation practices for newborns in a South-Eastern State, Nigeria by Chika Chioma Harriet Odira, Blessing Tochukwu Onyeje, Edith Anulika Udeogalanya, Oluwaseyi Isaiah Olabisi, Deborah Tolulope Esan

“…Results The majority (83.3%) of mothers practiced appropriate thermoregulation for their newborns, while only 23.8% and 41.3% practiced exclusive breastfeeding and proper cord care, respectively. …”
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Efficacy and safety of immune checkpoint inhibitors for brain metastases of non-small cell lung cancer: a systematic review and network meta-analysis by Bin Liu, Jie Chen, Mingqi Luo

“…SUCRA ranking identified pembrolizumab as the most effective agent for OS improvement (SUCRA 71%), while camrelizumab showed superior PFS benefits (SUCRA 92%). …”
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Switching from Dupilumab to Abrocitinib in Patients With Moderate-to-Severe Atopic Dermatitis: A Post Hoc Analysis of Efficacy After Treatment With Dupilumab in JADE DARE by Jonathan I. Silverberg, Eric L. Simpson, Andrew E. Pink, Stephan Weidinger, Gary Chan, Pinaki Biswas, Claire Clibborn, Erman Güler

“…Most dupilumab responders for IGA, EASI, PP-NRS, and DLQI at DARE Week 26 maintained their responses 12 weeks after switching to abrocitinib, while a considerable proportion of IGA, EASI, PP-NRS, or DLQI dupilumab nonresponders gained response after switching to abrocitinib. …”
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Effects of progressive versus consistent dose of caffeine ingestion on volleyball players’ exercise performance adaptations following plyometric jump training by Ganfang Zhu, Keqi Fu, Yangzheng Xie

“…BackgroundThe consumption of caffeine (CAF) to enhance adaptations in athletes has been documented in prior studies; however, the identification of an optimal approach for CAF supplementation during short-term interventions remains unclear. …”
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Exogenous melatonin as a disease-modifying therapy for epilepsy by P. V. Moskaleva, N. A. Shnayder, N. G. Neznanov, D. V. Dmitrenko, V. A. Golokov, R. F. Nasyrova

“…In some forms of epilepsy, circadian dysrhythmias and sleep disorders can trigger the development of epileptic seizures, while in others - seizures develop from the REM-phase of sleep.The aim is to review and analyze studies on the efficacy and safety of exogenous melatonin as an additional medication for disease-modifying therapy in pediatric and adult patients with epilepsy.Materials and methods. …”
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Evolution of Research on Artificial Intelligence for Heart Failure: A Bibliometric and Visual Analysis by Meng L, Lian K, Zhang J, Li L, Hu Z

“…Moreover, Frontiers in Cardiovascular Medicine is the leading journal with the most articles published in this area, while Circulation ranks the highest in co-citations. …”
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Efficacy of daily versus alternate day oral iron supplementation for management of anaemia among general population: a systematic review and meta-analysis by Anupkumar D. Dhanvijay, Vipin Patidar, Jayvardhan Singh, Subodh Kumar, Shiv Kumar Mudgal, Seshadri Reddy Varikasuvu, Rajesh Kumar

“…Abstract Background Iron deficiency anemia (IDA) remains a prevalent global health issue. While oral iron therapy is the first-line treatment, the optimal dosing strategy—daily versus alternate-day—remains debated, especially for general population use. …”
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Metabolic, Inflammatory and Imaging Biomarkers in Evaluation of Coronary Arteries Anatomical Stenosis in Patients with Stable Coronary Artery Disease by O. A. Koshelskaya, T. E. Suslova, I. V. Kologrivova, N. Y. Margolis, O. A. Zhuravleva, O. A. Kharitonova, I. V. Vinnitskaya

“…To reveal the statistically significant determinants of the coronary artery (CA) stenosis ≥70% in patients with chronic stable CA disease receiving drug therapy.Material and methods. The study included 68 patients (aged 59.6±6.4 years) with stable CA disease and optimal cardioactive therapy. …”
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Mechanical behavior of hybrid custom implant abutments with various crown materials: a 3D finite element analysis by Pongsakorn Poovarodom, Guilherme Faria Moura, Fabio Antonio Piola Rizzante, Chaiy Rungsiyakull, Jarupol Suriyawanakul, Pimduen Rungsiyakull

“…PICN, Zirconia, Titanium, and Lithium Disilicate abutments showed peak principal stresses between 77 and 85 MPa, while PEEK variants reduced stress in the custom abutment (35–66 MPa) but increased it in the Ti-base (356–405 MPa). …”
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Simulation Analysis of Water Resource Scheduling in Nansu River Based on Coupled Water Quality-Quantity Model by HOU Xiang-dong, ZHAO Xiang-ling

“…Conducting research on water quality and quantity in rivers that flow through urban areas and serve functions such as water supply and irrigation, and implementing rational scheduling, is of significance for ensuring a healthy aquatic ecosystem and enhancing the well-being of local residents. [Methods] The Nansu River Basin was selected as the research area. …”
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Risk factors for anorectal and associated malformations in German children: A 10-year analysis by Melanie Kapapa, Nastassja Becker, Alexandre Serra

“…The aim of the study was to evaluate possible prenatal risk factors for ARM in a tertiary hospital. Methods: A case–control design was used to compare risk factors in ARM (n = 44) to a control group (CG; n = 26). …”
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The Carbon Reduction Contribution of Battery Electric Vehicles: Evidence from China by Ying Sun, Le Xiong, Rui Yan, Ruizhu Rao, Hongshuo Du

“…The ED measure primarily impacts the waste treatment process (WTP) stage, followed by the vehicle cycle, while the EEI measure only affects the WTP stage. …”
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