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6541
Investigating the Relationship between Financialization and Long-Term Use of Short-Term Debt
Published 2025-09-01“…The statistical sample consists of 143 active firms listed on the Tehran Stock Exchange over a ten-year period, from 2013 to 2022. The regression method was employed to estimate the models and test the research hypotheses. …”
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6542
Multi-scenario simulation of LULC and carbon dynamics in karst regions using the PLUS model
Published 2025-07-01“…Studying the relationship between land use transition and carbon sources/sinks is of great significance for optimizing regional land use planning, achieving sustainable development, and the “double carbon” goals. …”
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6543
Enhanced transport in non-newtonian nano-level fluid flow over a rotating disk under radiation and soret–dufour effects: A numerical insight
Published 2025-09-01“…These ODEs are then solved numerically using the BVP4c collocation method in MATLAB, over the interval [0,7], with boundary conditions applied at the disk surface and far field. …”
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6544
Performance of Mushrooms in Fermented Beverages: A Narrative Review
Published 2025-01-01“…Fermentation significantly enhances the nutritional content and bioavailability of mushrooms, making it an ideal method to maximize the health benefits and sensory appeal of mushroom-based beverages. …”
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6545
Rapid and sensitive detection of bovine Theileria annulata parasite based on ERA-CRISPR/Cas12a technology
Published 2025-08-01“…Among three primer pairs and two CRISPR RNA (crRNA) candidates screened, the F3/R3 primer set combined with crRNA1 demonstrated the best performance. The optimized ERA protocol achieved complete amplification within 20 min at 37°C. …”
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6546
Development of a four autophagy-related gene signature for active tuberculosis diagnosis
Published 2025-05-01“…BackgroundTuberculosis (TB) diagnostics urgently require non-sputum biomarkers to address the limitations of conventional methods in distinguishing active TB (ATB) from latent infection (LTBI), healthy controls (HCs), and TB-mimicking diseases (ODs, other diseases).MethodsTranscriptomic data from GSE83456 and GSE152532 were combined to form the selection dataset. …”
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6547
Revolutionizing total hip arthroplasty: The role of artificial intelligence and machine learning
Published 2025-01-01“…Abstract Purpose There has been substantial growth in the literature describing the effectiveness of artificial intelligence (AI) and machine learning (ML) applications in total hip arthroplasty (THA); these models have shown the potential to predict post‐operative outcomes using algorithmic analysis of acquired data and can ultimately optimize clinical decision‐making while reducing time, cost and complexity. …”
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6548
Comparison of the application value of contrast-enhanced ultrasound and contrast-enhanced CT in puncture biopsy of peripheral pulmonary lesions
Published 2025-04-01“…The average number of pleural punctures, puncture time, satisfaction with the first puncture specimen, diagnostic accuracy and complication rate were compared between the two guidance methods.Results① Compared with the CECT group, the CEUS-guided group required fewer pleural punctures (2.5 vs. 4.1 times) and shorter puncture time (24 minutes vs. 42 minutes) on average, and the difference was statistically significant (P<0.001). ② In terms of complications, the incidence of pneumothorax (3.1% vs. 8%) was lower in the CEUS group, while the incidence of bleeding (1.5% vs. 3.1%) had no significant difference between the two groups ③ When the diameter of the lesion is <3 cm, the specimen satisfaction and diagnostic accuracy of the CEUS group are lower than those of the CECT group (71.0% vs. 88.3%, 64.5% vs. 86.7%). …”
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6549
Exploring Human Use of Monoclonal Antibodies Against Critical Bacteria: A Scoping Review of Clinical Trials
Published 2025-07-01“…This review evaluates the clinical efficacy, safety, and limitations of mAbs targeting critical bacterial pathogens, analyzing factors influencing therapeutic outcomes, and proposing strategies to optimize their clinical application. Methods A comprehensive analysis of clinical trials investigating antibacterial mAbs was conducted. …”
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6550
CircEPDR1 regulates proliferation and differentiation of goat skeletal muscle satellite cells through miR-345-3p/Akirin1 axis
Published 2025-08-01“…Objective Circular RNAs (circRNAs) play pivotal roles in regulating the growth and development of mammalian skeletal muscle This study aims to provide new insights into the molecular regulatory network that underlies skeletal muscle development, presenting valuable targets to enhance and optimize livestock production performance. Methods In this study, we anchored a novel circRNA from previous circRNA sequencing data from goat skeletal muscle and named it circEPDR1, which was confirmed through en-zymatic digestion and Sanger sequencing. …”
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6551
Differences in neuronal ciliation rate and ciliary content revealed by systematic imaging-based analysis of hiPSC-derived models across protocols
Published 2025-04-01“…Interestingly, we found that while GPR161 signal almost completely disappeared from cilia upon Sonic hedgehog (SHH) stimulation in NSCs and immature neurons, this was not the case in more mature neurons, suggesting a possible developmental time window for cilia-dependent SHH signaling.ConclusionTaken together, our results provide a systematic description of cilia in hiPSC-derived neuronal cells generated with different protocols, underscoring the importance of selecting the optimal model system and controls for investigating primary cilia in hiPSC-derived neuronal cells.…”
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6552
Bevacizumab, tislelizumab and nab-paclitaxel for previously untreated metastatic triple-negative breast cancer: a phase II trial
Published 2025-04-01“…Background Optimal first-line therapy for metastatic triple-negative breast cancer (mTNBC) varied in different situations. …”
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6553
Adaptive Fast Refocusing for Ship Targets With Complex Motion in SAR Images
Published 2025-01-01“…Ships are subjected to complex movements by sea winds and waves while traveling, which can cause them to appear heavily defocusing in SAR images. …”
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6554
Reliable models for calculating the condensation heat transfer inside smooth helical tubes of different flow directions utilizing smart computational techniques
Published 2025-08-01“…Abstract Condensers with helical tubes have received much attention in diverse industries. The optimal design of the mentioned equipment necessitates predictive tools for calculating the condensation heat transfer coefficient (HTC). …”
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6555
Multimodal Feature-Driven Deep Learning for the Prediction of Duck Body Dimensions and Weight
Published 2025-05-01“…Accurate body dimension and weight measurements are critical for optimizing poultry management, health assessment, and economic efficiency. …”
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6556
Adoptively transferred macrophages for cancer immunotherapy
Published 2025-05-01“…Here, we demonstrate that adoptively transferred macrophages, with optimal activation prior to administration, act as a potent cellular cancer therapeutic platform against a murine melanoma model.Method The macrophage therapy was prepared from bone marrow-derived macrophages, pretreated ex vivo with an activation cocktail containing interferon-γ, tumor necrosis factor-α, polyinosinic:polycytidylic acid, and anti-CD40 antibody. …”
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6557
Explainable machine learning model for predicting the transarterial chemoembolization response and subtypes of hepatocellular carcinoma patients
Published 2025-07-01“…We developed a Machine Learning (ML)-based model integrating routine clinical variables to preoperatively predict TACE efficacy, enabling tailored TACE candidate selection and optimized therapeutic decision-making. Methods This retrospective multicentre study enrolled treatment-naive HCC patients undergoing initial TACE from two independent cohorts: the First Affiliated Hospital of Wenzhou Medical University (training cohort) and Wenzhou Central Hospital (external validation cohort). …”
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6558
Impacts of Ecological Restoration Projects on Ecosystem Carbon Storage of Tongluo Mountain Mining Area, Chongqing, in Southwest China
Published 2025-05-01“…The methodology quantified carbon storage variations among engineered restoration (ER), natural recovery (NR), and unmanaged sites (CWR) while identifying optimal vegetation configurations for karst ecosystems. …”
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6559
The Effectiveness of Teaching Spiritual Concepts Based on Mention and Prayer on Moral Intelligence and Quality of Attachment in Students
Published 2024-08-01“…The present study aimed to examine the effectiveness of spiritual concepts training centered around mention and prayer on moral intelligence and attachment quality of students. The research method was quasi-experimental with a pre-test, post-test, and follow-up design (for a period of 3 months) with a control group. …”
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6560
Three-dimensional finite element analysis of teeth displacement patterns under four anchorage designs for maxillary molar distalization using clear aligners: a real-case based simu...
Published 2025-07-01“…Abstract Objective To explore the three-dimensional (3D) displacement patterns of maxillary molar distalization using clear aligners (CA) under four anchorage designs and provide clinical guidelines for optimal traction methods. Materials and methods A 3D finite element model was constructed based on CBCT and digital models from an adult patient requiring maxillary molar distalization. …”
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