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6441
The Choice of Tactics for Surgical Treatment of Acute De Bakey Type I Aortic Dissection in a Multidisciplinary Surgical Hospital
Published 2023-04-01“…Hospital mortality of complicated forms of dissection remains significantly higher — 33.5% versus 18.5% of uncomplicated course. 2. The most optimal method of distal reconstruction in patients with the peracute stage of dissection is an open anastomosis with the aorta using the “hemi-arch” technique. 3. …”
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6442
Synthesis and application of fucoidan biological superabsorbent polymer
Published 2025-07-01“…The SEM analysis revealed a porous and loose network structure, while FT-IR confirmed the formation of a graft copolymer of fucoidan and AA. …”
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6443
Modulating TNFα activity allows transgenic IL15-Expressing CLL-1 CAR T cells to safely eliminate acute myeloid leukemia
Published 2020-10-01“…Background C-type lectin-like molecule 1 (CLL-1) is highly expressed in acute myeloid leukemia (AML) but is absent in primitive hematopoietic progenitors, making it an attractive target for a chimeric antigen receptor (CAR) T-cell therapy. Here, we optimized our CLL-1 CAR for anti-leukemic activity in mouse xenograft models of aggressive AML.Methods First, we optimized the CLL-1 CAR using different spacer, transmembrane and costimulatory sequences. …”
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6444
Fuzzy Hypothesis Testing for Radar Detection: A Statistical Approach for Reducing False Alarm and Miss Probabilities
Published 2025-07-01“…This enhances robustness, particularly in scenarios where rapid and accurate classification is essential. The proposed methods are validated through both real and synthetic simulations of radar measurements, demonstrating their ability to enhance detection reliability across diverse conditions. …”
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6445
A clinical data-driven machine learning approach for predicting the effectiveness of piperacillin-tazobactam in treating lower respiratory tract infections
Published 2025-03-01“…The success group comprised 995 patients (75.7%), while the failure group consisted of 319 patients (24.3%). …”
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6446
Sustainable Lightweight Concrete Using Candlenut Shell as Coarse Aggregate: The Impact of Water-Cement Ratios on Strength and Density
Published 2025-07-01“…Concrete mixes were prepared using the absolute volume method, with w/c ratios ranging from 0.65 to 0.30, to identify the optimal balance. …”
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6447
Flow topology and thermal mechanism in turbulent channel flow with tapered V-shaped baffles
Published 2025-09-01“…The simulations are performed using the finite volume method in conjunction with the SIMPLE algorithm, and the Generalized k-ω (GEKO) turbulence model is employed to capture the flow dynamics. …”
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6448
A novel high-performance supercapacitor based on the innovated ternary CeO2@CoWO4/N-doped graphene nanocomposites
Published 2025-09-01“…The present work used multiple steps method to fabrication the three component CeO2@CoWO4/N-doped graphene (CCNG) as active material for supercapacitor application for the first time. …”
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6449
Role of Post-Operative Rehabilitation in TM Joint Arthritis: Functional Outcomes of Interposition Trapeziectomy vs. Prosthesis
Published 2025-05-01“…However, the role of post-operative rehabilitation in optimizing outcomes for these procedures remains underexplored. …”
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6450
Neck dose-limiting rings reduce head and neck lymphedema in early nasopharyngeal carcinoma patients undergoing IMRT: a dosimetric-clinical validation
Published 2025-04-01“…Through dosimetric and clinical cohort verification studies, the optimal limiting dose for the cervical anterior and posterior dose limiting rings has been determined, hoping to provide a new design method of IMRT plans to reduce head and neck lymphedema after radiotherapy for early NPC.…”
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6451
A Novel QR Code–Based Solution for Secure Electronic Health Record Transfer in Venous Thromboembolism Home Rehabilitation Management: Algorithm Development and Validation
Published 2025-08-01“…Specifically, BPE tokenizes medical text, while Avro serializes JSON (JavaScript Object Notation) objects, contributing to data encryption. …”
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6452
The emerging role of next-generation sequencing in minimal residual disease assessment in acute lymphoblastic leukemia: a systematic review of current literature
Published 2025-04-01“…Challenges such as high costs, complex bioinformatics analysis and the need for standardization remain. While its integration into clinical practice holds significant promise, further research is needed to establish standardized protocols, cost-effectiveness, and its optimal role in treatment decision-making. …”
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6453
Determining mosquito age using surface-enhanced Raman spectroscopy and artificial neural networks: insights into the influence of origin and sex
Published 2025-06-01“…However, traditional methods, such as tracheole morphology analysis, are labor-intensive and have limited scalability. …”
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6454
Students’ motives for enrolling in the master of nursing program in Croatia despite degree recognition uncertainties: a cross-sectional study
Published 2025-05-01“…Most BN and MN students, while cognizant of the limited MN-recognized roles, were primarily motivated to enrol in MN programs to deepen knowledge (94%) and advance career opportunities. …”
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6455
Predictors of long-term outcome of patients with schizophrenia in Africa: systematic review and meta-analysis
Published 2025-02-01“…Given the heterogeneity of outcomes, region-specific strategies are essential to optimize care.…”
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6456
Independent and combined relationships between nighttime light exposure, air pollution, PM2.5 constituents, greenness and diabetes or high blood sugar: a national prospective cohor...
Published 2025-08-01“…Methods Using data from the China Health and Retirement Longitudinal Study (CHARLS, 2011–2015), we included 11,865 participants aged ≥ 45 years without baseline D/HBS. …”
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6457
Comparison of Factors Affecting Quality of Life in Patients with Acute Ischemic Stroke Across Different Stroke Severities
Published 2025-04-01“…The aim of this study was to address this critical issue, refining treatments to enhance long-term QoL and optimize resource use. Methods In this multicenter prospective study conducted in China, patients with AIS were assessed using the EuroQol-5 Dimension (EQ-5D) questionnaire at admission and 1 year later. …”
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6458
Effectiveness of anabolic and anti-resorptive agents for preventing postmenopausal osteoporosis fractures: a systematic review and network meta-analysis
Published 2025-07-01“…We aimed to estimate anti-osteoporosis effect and compliance of different anabolic and anti-resorptive agents to explore the optimal cycling strategy. Methods PubMed, Embase, Web of Science, and Cochrane Library were searched for randomized controlled trials comparing anabolic or anti-resorptive agents with placebo or each other in postmenopausal women with osteoporosis or osteopenia, reporting outcomes on bone mineral density (BMD) change, fracture incidence, or treatment discontinuation from inception to February 1, 2024. …”
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6459
From gaps to compliance: a 12-year retrospective cohort study of trends in mismatch repair protein testing and Lynch syndrome identification in colorectal cancer in Central Switzer...
Published 2025-07-01“… STUDY AIM: Alongside an analysis of incidence trends in colorectal cancer and Lynch syndrome over time, the study sought to evaluate the implementation and trends of reflex testing for mismatch repair proteins and key mutations in relevant genes (BRAF, KRAS, NRAS) in colorectal cancer in Central Switzerland from 2011 to 2022, specifically assessing adherence to the Swiss Academy for Quality in Medicine (SAQM) guidelines, in order to identify any gaps or inconsistencies in testing practices that may hinder the diagnosis of Lynch syndrome or microsatellite instability, highlighting areas requiring improvements for optimal patient care. METHODS: This retrospective study enrolled 2602 patients with 2673 histologically confirmed colorectal cancers. …”
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6460
Prediction of joint deformity after MIPPO with double reverse traction repositor based on Hounsfield units derived from CT scans
Published 2025-07-01“…Abstract Background Tibial plateau fractures (TPFs) account for approximately 1% of all fractures and notably 8% of fractures among the elderly. While both surgical and non-surgical interventions can yield promising short-term results, the long-term implications, particularly the risk of post-traumatic osteoarthritis (PTOA), necessitate further investigation. …”
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