Long-term effects of orthognathic surgery on masticatory function in individuals with cleft lip and palate: A prospective study by Patricia Martins Bueno, Paulo Alceu Kiemle Trindade, Laís Hollara Medeiros, Leide Vilma Fidélis da Silva, Ivy Kiemle Trindade-Suedam

“…Objective: To prospectively evaluate the long-term effects of orthognathic surgery on masticatory function in individuals with repaired complete cleft lip and palate and to compare the results with a control group. Material and methods: A total of 40 individuals were prospectively analyzed before (PRE-ORTHOG) and approximately 12 months after orthognathic surgery (POST-ORTHOG). …”
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Global, regional, and national burden of Pediatric and adolescent thyroid cancer from 1990 to 2021: a statistical analysis of prevalence, incidence, and DALYs by Rui Zhang, Zhenxin Mei, Shan Feng, Zongcun Chen

“…In the 5 SDI regions, the prevalence and incidence are showing an upward trend, while DALYs rates showed divergent patterns: a marginal increase in low-middle SDI regions (EAPC=0.13, 95% UI: -0.07-0.32) contrasted with declining trends in other regions. …”
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Correcting Tibiotalar Alignment Correlates with FAO Changes after Total Ankle Replacement by Ricardo Villar MD, Emily Teehan MS, Kira Lu, Ranqing Lan MS, Patricia Friedmann MS, Jensen Henry MD, Constantine Demetracopoulos MD

“…Submission Type: Ankle Arthritis Research Type: Level 3 - Retrospective cohort study, Case-control study, Meta-analysis of Level 3 studies Introduction/Purpose: Re-establishing anatomic ankle and foot alignment is critical to optimize clinical outcomes and longevity of total ankle replacement (TAR). …”
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Effects of Stretching and Resistance Training on Psychophysical Awareness: A Pilot Study by Giovanni Esposito, Rosario Ceruso, Pietro Luigi Invernizzi, Vincenzo Manzi, Gaetano Raiola

“…Such findings offer practical implications for coaches seeking to optimize flexibility training by integrating alternative methods that promote both physical and perceptual adaptations.…”
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Neoadjuvant PD-1/PD-L1 inhibitors combined with chemotherapy in gastric cancer and gastroesophageal junction adenocarcinoma: a systematic review and meta-analysis of single-arm stu... by Jun Leng, Jun Leng, Min Liu, Min Liu, Qianwen Wang, Qianwen Wang, Huaiwu Jiang, Jin Chen

“…BackgroundNeoadjuvant chemotherapy, particularly neoadjuvant immunotherapy, has achieved significant progress in treating gastric cancer (GC) and gastroesophageal junction (GEJ) adenocarcinoma. While PD-1/PD-L1 inhibitors have improved survival outcomes in some patients, the efficacy of combining neoadjuvant chemotherapy with PD-1/PD-L1 inhibitors remains insufficiently validated.ObjectiveThis study aims to evaluate the efficacy and safety of neoadjuvant chemotherapy combined with PD-1/PD-L1 inhibitors in GC/GEJ adenocarcinoma and enhance statistical power through meta-analysis.MethodsWe systematically searched PubMed, Embase, Web of Science, and the Cochrane Library up to October 5, 2024, for original clinical studies on neoadjuvant PD-1/PD-L1 inhibitors combined with chemotherapy for GC/GEJ adenocarcinoma. …”
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Efficacy and safety of puerarin injection as an adjunctive therapy for chronic heart failure: a systematic review and meta-analysis by Hesong Fan, Jingrong Yang, Huaizhe Wang, Shuli Zong, Yiwei Qu, Kefei Wang, Fengyi Zhang, Xiao Li

“…The combination therapy demonstrated both a significantly increased total effectiveness rate (RR = 1.26, 95% CI [1.21, 1.31], P < 0.01) and improved hemodynamic parameters, along with favorable modulation of oxidative stress markers evidenced by elevated superoxide dismutase, glutathione peroxidase, and catalase levels concomitant with reduced lipid peroxidation and malondialdehyde concentrations.ConclusionThis meta-analysis suggests that adjunctive puerarin injection with conventional therapy may provide comprehensive benefits for chronic heart failure management, including improved clinical outcomes, enhanced cardiac function, attenuated ventricular remodeling, optimized hemodynamic performance, and reduced oxidative stress, while maintaining a safety profile comparable to conventional therapy. …”
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Global, regional, and national epidemiology of Intracerebral Hemorrhage among women of childbearing age (1990–2021): incidence, mortality, DALYs, and risk factor analysis by Yuan Li, Wei Yang, Jixiang Xu, Guoming Pu, Sujun Liu, Chunmei Chen, Xiufang Che, Hua Huang, Hongjiang Pu, Hongjiang Pu

“…The burden was linked to the Socio-Demographic Index (SDI), with lower SDI regions experiencing increasing burden, while higher SDI regions saw a decline. Regional disparities were observed, and certain factors like environmental particulate pollution showed an upward trend. …”
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Use of glycoprotein IIb/IIIa inhibitors in myocardial infarction in the Russian Federation, according to the Russian Registry of Acute Myocardial Infarction REGION-IM by N. S. Kostritca, R. M. Rabinovich, R. M. Shakhnovich, I. S. Yavelov, R. G. Gulyan, Yu. K. Rytova, S. N. Tereschenko, A. D. Erlikh, D. V. Pevzner

“…Further research is needed to develop an optimal protocol for glycoprotein IIb/IIIa inhibitors administration in AMI.…”
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Operation strategy simulation of the heating system for moderately deep geothermal resources by Yongzhe ZHAO, Baofeng ZHAO, Zhenyang HU, Li GOU, Dingshan DU, Chenglu LIU

“…It is necessary to prevent resource waste while utilizing geothermal energy. MethodsBased on a heating project using moderately deep geothermal resources in the Guanzhong Basin, Shaanxi Province, this study established a dynamic simulation model using the TRNSYS transient simulation software. …”
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Mutation-based, neoadjuvant treatment for advanced anaplastic thyroid carcinoma by Sabine Wächter, Detlef K. Bartsch, J. Riera Knorrenschild, Anika Pehl, Friederike Eilsberger, Andreas Pfestroff, Markus Luster, Katharina Holzer, Andreas Neubauer, Elisabeth Maurer

“…This study aimed to investigate whether mutation-based neoadjuvant therapy can convert an initially unresectable tumor into a resectable state, optimizing local tumor control and prolonging overall survival.MethodsPatients with stages IVB and limited IVC BRAFV600E-negative ATC received immediate combination therapy consisting of the multikinase inhibitor (mKI) lenvatinib and the immune checkpoint inhibitor (ICI) pembrolizumab upon diagnosis. …”
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The Impact of Protein and Amino Acid Supplementation on Muscular Strength and Endurance in Recreational Gym-Goers During 8-Week Resistance Training by Sandor-Richard Nagy, Magdalena Mititelu, Ruxandra-Cristina Marin, Violeta Popovici, Annamaria Pallag, Tünde Jurca

“…It also investigates the NS’s impact on resistance training (RT) performance. <b>Methods:</b> All participants (<i>n</i> = 218) were regular members of two gym centers in Oradea. …”
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Determinants of Digital Health Literacy: International Cross-Sectional Study by Connor S Qiu, Tetiana Lunova, Geva Greenfield, Gabriele Kerr, Ömrüm Ergüven, Thomas Beaney, Benedict Hayhoe, Erik Mayer, Azeem Majeed, Ana Luisa Neves

“…Compared to participants from Germany, those from the United Kingdom (β=2.1; 95% CI 1.7-2.5; P<.001) and Sweden (β=2.9; 95% CI 2.4-3.4; P<.001) had higher digital health literacy scores, while there was no difference with Italian participants (P=.399). …”
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Efficacy of see-and-treat hysteroscopy versus traditional hysteroscopy in moderate-to-severe intrauterine adhesions by LI Qiurong, CAI Huifen, WANG Yanzhou

“…Conclusion‍　‍The see-and-treat approach is a safe, feasible, and highly efficient strategy for integrating the diagnosis and treatment of IUA, enabling maximal minimization of surgical trauma while optimizing time and cost efficiency. …”
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Population dynamics and monitoring applied to decision-making by M. J. Conroy, D. C. Lee

“…The results have important implications for managers, who may endeavor to cut costs by using index–based methods, while in the process incur these hidden costs of loss of decision utility. …”
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BSF maggot and Azolla pinnata based poultry feed processing to improve the economy ressilience by Andrew Setiawan Rusdianto, Fani Fahrurrijal Al Farizi, Erika Dwi Silawati, Nurul Aisyah, Alma Tsabita Kamilah, Maesarani Salsalina Sitepu, Tabah Aji Pamungkas, Rindi Mayang Sari, Aminatuz Zuhriyah, Susi Susanti, Lubna Rahman

“…Additionally, soybean waste in this village has not been optimally utilized. The Mahasiswa Berdesa program aims to develop poultry feed based on Black Soldier Fly (BSF) maggot, Azolla pinnata, and soybean meal with nutrients that meet poultry needs, while also improving the local economy through the sale of products derived from BSF maggot, Azolla pinnata, and soybean meal as poultry feed. …”
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Identification of green leafhoppers (cicadellidae) in vineyards through an automatic image acquisition system from yellow sticky traps associated with deep-learning by Proença Maria da Conceição, Rebelo Maria Teresa, Valent Riccardo, Mateus Rebeca, Gaspar Pedro Diniz, Lopes Carlos Manuel, Franco José Carlos

“…The results demonstrated the algorithm’s capability to accurately identify green leafhopper species, improving the speed of identification compared to conventional methods while maintaining a high level of precision (80%), and a harmonic mean of the precision and recall (F1) of 0.85. …”
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The Impact of Conservative Accounting on the Speed of Leverage Adjustment in Response to Stock Price Crash Risk by Abdullah Khaled Azeez, Akbar Zavari Rezaei, Mehdi Heidari

“…This study aimed to investigate whether accounting conservatism could enhance the speed of leverage adjustment in the context of stock price crash risk. Materials & MethodsThis study employed both experimental and statistical methods to test the hypotheses. …”
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Comparative study on fretting wear damage mechanisms of 316L steel in dry air and liquid lead-bismuth eutectic environments by Qi Sun, Yu Qin, Haowen Tang, Qian Yang, Pengfei Yang, Xiaoqiang Fan, Minhao Zhu

“…The results in this work are not only expected to better understand failure behavior of fretting wear in liquid LBE environment, but also provide a possible guide for selecting the optimal damage protection method.…”
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Selective Extraction of Zirconium from Sulfuric Acid Solutions at High Concentration with Trioctylamine (TOA) by Shuo Tian, Jing Song, Hongqian Sun, Congcong Zhao, Zhiyu Zhang, Mingming Han, Tao Qi

“…Under these conditions, the single-stage extraction rate of Zr is 61.23%, while the Hf is almost not extracted. The mechanism of Zr extraction by TOA was studied through the saturation capacity and slope methods. …”
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Variability in surgical treatment of metastatic colorectal cancer (literature review) by A. Yu. Dobrodeev, D. N. Kostromitsky, S. G. Afanasyev, A. S. Tarasova, N. N. Babyshkina, A. A. Ponomareva

“…Given the poor survival with currently approved methods, the development of the optimal treatment options is needed.The purpose of the study was to search for data on the development of surgical techniques for the treatment of patients with metastatic CRC (mCRC) with isolated liver metastasis.Material and Methods. …”
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